• 한방안이비인후피부과학회지
• /
• 제30권3호
• /
• pp.31-45
• /
• 2017

Objectives : Adenophorae Radix(AR) is the dried root of Adenphora triphylla var. japonica HARA. AR has the efficacy of clarifying lung, emitting pus, expelling wind, stopping pruitus and so on. Recently, various studies are being done about anti-oxidative, immunomodulatory and anti-inflammatory effects of AR. So, we expected AR has an availability that can improve symptoms of atopic dermatitis(AD). Methods : In this study, we measured body weight, weight of ear, thickness of ear skin and dorsum skin, symptom score, reproduction rate of splenocytes in vivo and in vitro of mouse with AD induced by DNCB. We experimented with five groups of 9 mice, such as normal group, control group, AR spread(ARS) group, AR feeding(ARF) group, AR spread&feeding(ARSF) group. Results : Control group of body weight significantly reduced and APSF group significantly increased in the first and second week. In weight of ear and thickness of ear skin and dorsum skin, control group significantly increased and ARSF group significantly decreased. In macrophotography viewpoint of dorsal skin, ARS group, ARF group and ARSF group decreased severe pigmented skin lesion, erythema and desquamation as compared with control group. Especially ARSF group showed significant drop. ARS group, ARF group and ARSF group compared to control group were improved in histopathology observation. In vitro and in vivo, treatment group of AR increased proliferation rate of splenocytes, specially in vitro significantly. Conclusions : This experiment indicates Adenophorae Radix extracts is effective on AD induced by DNCB in mice.

• 혜화의학회지
• /
• 제10권1호
• /
• pp.395-415
• /
• 2001

A general concept of Geun includes the soft organizations such as a muscle, a myofascia, a tendon and a ligament, cartilages and nerves that surround it. The main function of it is a movement of the body such as a flextion and a extension, a connection of the joints, and a construction of the body shape. Lately, we consider Geun important little by little, develop a variety of the therapeutic measures which make use of it, and apply it to the treatment in the oriental medicine, And the therapeutic measures which utilize Geun will be developed from now on. Therefore, this study reviewed and analyzed the direction of the research referred to Geun in the oriental medicine and the tendency to the experiment to grow the study referred to Geun in oriental medicine continuously and developed the new direction. This study collected 44's theses reported in the oriental medical journal and analyzed in accordance with the journal, time, form and topics. The following results were obtained in this study; 1. In the theses referred to Geun, the journal of Korean acupuncture & moxibustion society and of Korean oriental medicine have the most of them(11's theses) and at the next the journal of oriental rehabilitation medicine has 9's theses. 2. By analyzing the form of the theses, these were classified into the theoretical, experimental and clinical studies. The theoretical these occupied 39%, the experimental theses 54%, and the clinical theses 7%. 3. By analyzing the theses referred to Geun, these were classified into the muscular abnormality - such as a powerlessness, a injury, a atrophy, a disorder, and a pain - the theory of muscles along the regular meridians, the muscular organization, the therapeutic measures, the manipulation and so on. 4. The theses of the muscular abnormality occupied 30% of them referred to Geun and the theory of muscles along the regular meridians 20%, the muscular organization 12%, the therapeutic measures 12%, and the manipulation 8%. According to the above results, the study of the new field referred to Geun and the clinical report are indispensable since the field is limited and the tendency is theoretical and experimental.

• The Korean Journal of Physiology and Pharmacology
• /
• 제21권6호
• /
• pp.625-632
• /
• 2017

Familial Parkinson's disease (PD) has been linked to point mutations and duplication of the ${\alpha}$-synuclein (${\alpha}$-syn) gene. Mutant ${\alpha}$-syn expression increases the vulnerability of neurons to exogenous insults. In this study, we developed a new PD model in the transgenic mice expressing mutant hemizygous (hemi) or homozygous (homo) A53T ${\alpha}$-synuclein (${\alpha}$-syn Tg) and their wildtype (WT) littermates by treatment with sub-toxic (10 mg/kg, i.p., daily for 5 days) or toxic (30 mg/kg, i.p., daily for 5 days) dose of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Tyrosine hydroxylase and Bcl-2 levels were reduced in the ${\alpha}$-syn Tg but not WT mice by sub-toxic MPTP injection. In the adhesive removal test, time to remove paper was significantly increased only in the homo ${\alpha}$-syn Tg mice. In the challenging beam test, the hemi and homo ${\alpha}$-syn Tg mice spent significantly longer time to traverse as compared to that of WT group. In order to find out responsible proteins related with vulnerability of mutant ${\alpha}$-syn expressed neurons, DJ-1 and ubiquitin enzyme expressions were examined. In the SN, DJ-1 and ubiquitin conjugating enzyme, UBE2N, levels were significantly decreased in the ${\alpha}$-syn Tg mice. Moreover, A53T ${\alpha}$-syn overexpression decreased DJ-1 expression in SH-SY5Y cells. These findings suggest that the vulnerability to oxidative injury such as MPTP of A53T ${\alpha}$-syn mice can be explained by downregulation of DJ-1.

• Tuberculosis and Respiratory Diseases
• /
• 제63권5호
• /
• pp.444-448
• /
• 2007

저자 등은 대학 병원 응급실을 내원한 2명의 환자에서 근육내 자극 요법 후 부작용으로 발생한 의인성 기흉의 증례를 경험하였기에 보고하는 바이다.

• 한국한의학연구원논문집
• /
• 제15권2호
• /
• pp.101-109
• /
• 2009

The Pulse diagnosis is in the boundary of the Four Examinations, and it is called 切診, or palpation. It has a great impact on people in reminding of the Traditional Medicine that it is probably the first thing that people think of when they hear about Traditional Medicine. Hu-Jun quoted in the Treasured Mirror of Eastern Medicine "東醫寶鑑" that the doctor finds out the deficiency and the excess of the meridian of the patiant through the pulse, and that it is of the utmost necessity to know the "deficiency and the excess" of the meridian to decide the formula (君臣佐使) of the herbal medicine and the acupuncture/moxibustion treatment. The research on the studies of pulse diagnosis have been concentrated on the origin, history, and the theory of the pulse diagnosis throughout the years; however, the number of research on the image from the classics on pulse diagnosis have been less. With this in mind, this paper was written to study more on the origin and the history of the pulse diagnosis as well as to study on the image of pulse diagnosis shown on the classics on Traditional Medicine in China and Korea. The history of the pulse diagnosis has its root on the attempt to find out what is happening inside the body through the indication of the small changes of the pulse that is shown on the outer boundaries of the body. There were various kinds of pulse diagnosis including "Three positions and nine indicators method" and "Carotid pulsation and wrist pulse method" in the ancient period, and wrist pulse-taking method became the most popular since the completion of studying on palpation by 初보. The image of the palpation helps the rudimentary practitioners of Traditional Medicine. They are divided into two large categories, which are the area of diagnosis and the shape of the pulse itself. The historical classics including the image of the pulse diagnosis can be found since the Song Dynasty of China. There are various kinds of image of pulse diagnosis in the classic such as "The picture of the hand meridian" from "脈訣指掌病式圖說", "The picture of the image of meridian" from "察病指南", "The picture of the Seven exterior and Eight interior" from "校正圖注脈訣", and "The picture of the six parts of meridian" from Treasured Mirror of Eastern Medicine "東醫寶鑑". The Treasured Mirror of Eastern Medicine "東醫寶鑑" have analyzed the basic theories and made up the standards of pulse diagnosis by establishing "The picture of the six parts of meridian" based on "The method of placing the viscera and bowels corresponding to cun-guan-qi, or the meridian".

• 혜화의학회지
• /
• 제19권1호
• /
• pp.143-151
• /
• 2010

The purpose of this study is to survey the current status of the oriental medical service satisfaction and needs that the people who utilizing the medical services and suggest the primary factors of consumption and satisfaction in the oriental medical services the city of Asan. We analyze the use and satisfaction of the customers for the oriental medical services with using the questionnaires to the citizens of Asan. The method of this study is that the participants of the survey was 556 people of Asan City. The survey was conducted from August 15th, 2009 to September 15th, 2009(during 30 days) with disease index that specially developed as oriental medicine. The results of this study are as follows: 556 people were responded the survey. 471(84.7%) of respondents were who have ever been treated with oriental medical service and 85(15.3%) of respondents were who have never been treated with oriental medical service. 25(4.7%) of respondents were who doesn't believe the treat of oriental medicine. 76(13.6%) of respondents prefered the oriental medical service. 413(50.1%) of respondents prefered the acupuncture and moxa treatment and 280(33.9%) prefered the herbs. 227(39.6%) of respondents were treated for musculoskeletal disorders The conclusions from this study are as follows: Firstly, it was found that the people who prefer to use oriental medical services usually have one or more of these following diseases: musculoskeletal disorders, paralysis, unclear diseases or injuries. Secondly, the main factor of customers' satisfaction with oriental medical services lies in the age of the user. The more aged, the more high in customers' satisfaction with oriental medical services was found through the survey. The results of this study can be used to develop marketing strategies for oriental medical institutions in the city of Asan.

• 척추신경추나의학회지
• /
• 제8권2호
• /
• pp.67-78
• /
• 2013

Objectives : The present study examines the domestic trend of Osteoporosis studies in Korea. Method : We reviewed oriental medicine papers published in last ten years (2003-2012). Korean literature search was used for domestic Internet search portal. 'Naver specialized information retrieval', 'Korea Traditional Knowledge Portal', 'Korea Medical Information Portal (OASIS)',' Scientific and Technological Information Integration Services (NDSL)',' Academic Research Information Service (RISS)'as the primary destination of the search were. Since 2003 until 2012, the thesis o'f osteoporosis'and found 92 papers with the search term '(golwi)' to the search terms found in 3 papers Korean medical target of on going research trends in osteoporosis about investigated. Results : 1. We researched 95 papers in 15 journals and patterns of study were as follows : experimental studies were 79(83%), clinical studies were 12(13%), reviewed studies were 3(3%) and etc. were 1(1%). 2. The experimental studies(79) were divided into papers on efficiency testing of herbal medications(67) and herbal acupuncture(12). 3. The clinical studies(12) showed that research has been carried out in the fields of follow up surveys for the herbal medication efficiency testing, basic research, case report, the relativity of osteoporosis to age and sex, and the perception about osteoporosis and korean medicine treatment. 4. The reviewed studies showed that research has been carried out in the fields of osteoporosis about acient literature and domestic studies about herbal medication of osteoporosis. Conclusion : Reviewing the domestic trend of Osteoporosis studies and examining the strong and weak points of those treatments are essential for the future studies. It is anticipated that this review benefits the future in-depth study on the treatments for osteoporosis in Korean medicine.

• 근관절건강학회지
• /
• 제4권1호
• /
• pp.48-60
• /
• 1997

This study was undertaken to identify the musculotendinous problems and contributing factors to those problems In students majoring in musical instruments in Korea. The data were collected from March 2, 1996 to March 31, 1996 from 261 music students in various geographical areas. The data were analyzed for descriptive statistics, t-test, chi-square using SPSS $PC^+$ program. The results of this study were as follows : 1. In a questionnaire survey of 261 music students, one hundred twenty five(47.9%) reported having had various musculotendinous symptoms. Twenty seven students among the those who had previous symptoms(21.9%) reported the present symptoms. 2. The experience rates of musculotendinous problems in keyboard players, string players and woodwind players were 50.3%, 48.2%, 33.3% respectively. 3. Most of the students practiced most intensively during their high school years and the musculotendinous symptoms began at the same period. 4. Pain, tenderness and stiffness were the most common symptoms, while paresthesia and motor dysfunction were rare. This indicates that most players had muscle tendinous overuse, while small number had nerve entrapment and motor dysfunction. 5. In past and present symptoms, string players experienced musculotendinous symptoms mainly in both sides of shoulders, lumbar area, left finger, and left wrist, while keyboard players experienced more symptoms in the right wrist, shoulder, fingers than left side. 6. The major contributing factors to the symptoms were weight of instrument, types of instruments, types of daily activities, duration of practice, and playing technique. 7 The most frequent treatment modalities for the symptoms were acupuncture or moxibustion, other alternative therapy such as heat compress and massage. Through this study it was found that the musculotendinous problems might be increased along with their career, due to lack of knowledge about preventive measures and patterns of health behavior seeking alternative modalities rather than professional consultation. Therefore, preventive measures that focus on playing habits such as duration of practice, frequency of rest and position while playing should be developed and taught to the students, their parents, and music educators. Doctors who are interested in this area should attempt to correct the position and posture while playing of the posture. And measures for reduction of loading of instrument weight should also be developed.

• 한방재활의학과학회지
• /
• 제20권2호
• /
• pp.63-77
• /
• 2010

Objectives : It is known that abdominal obesity increases the possibility of cardiovascular diseases, early death, and metabolic syndrome including dyslipidemia and insulin resistance. Clinical trials have been under way to verify the effectiveness of treatment for abdominal obesity. The objective of this study is to set criteria about how effective oriental medicine and acupuncture are in abdominal obesity. Methods : I manually search "www.clinicaltrial.gov", 4 Korean medical databases and 4 Korean medical journals of abdominal obesity. Search terms used were "abdominal obesity" or "visceral obesity". In order to see detail review, searching was performed from 01, 01, 2005 to 11, 31, 2009. And I classified all the searched studies into design, intervention, purpose, end point, diseases, condition and etc. Results : 1. I could search total 67 trials in "www.clinicaltrial.gov". I found 9, 10, 13, 8, 6 clinical trial from 2005 to 2009 every year. 2. Test on both gender and adult or adult and senior have been most frequent. 3. Randomization clinical trial is 51 cases that occupied 96.2%. 38 cases use control group. 4. Body mass index(BMI) and waist circunference(WC) are major criteria of abdominal obesity clincal trial. WC, BMI, abdominal fat mass, body weight are measured at end point of abdominal obesity clincal trial. 5. I could search total 86 cases in domestic study. I found 15, 23, 23, 20, 5 cases from 2005 to 2009 every year. 6. Test on female and adult have been most frequent in domestic study. 7. Randomization clincal trial is only 2 cases that occupied 2.3%. 62 cases use control group in domestic study. 8. BMI, body fat percent, WC, visceral-subcutaneous fat ratio(VSR), waist-hip ratio(WHR) are criteria of abdominal obesity clincal trial in domestic study. WC, BMI, abdominal fat mass, body weight are measured at end point of abdominal obesity clincal trial in domestic study. Conclusions : To improve abdominal obesity study in traditional korean medicine, it is need to activate clinical trial, meta analysis, develope of clinical practice guidelines, co-works with conventional medicine and etc.

• Journal of Chest Surgery
• /
• 제42권6호
• /
• pp.744-748
• /
• 2009

배경: 이 연구를 통해 침습적인 시술이 증가 함에 따른 의인성 기흉의 원인과 그에 따른 이환율을 알고자 한다. 대상 및 방법: 2005년 1월부터 2008년 12월까지 의인성 기흉의 진단으로 입원치료를 받은 112명의 환자(20세부터 90세까지의 연령분포를 보인 65명의 남자 환자와 47명의 여자 환자)에게서 후향적으로 의무기록을 조사하였다. 결과: 의인성 기흉의 호발 원인은 경피적 폐생검(50), 중심정맥관 삽입(29), 침술(14), 흉수천자(8), 양압환기(7)의 순서였다. 60명의 환자에서 흉관삽관술을 통해 치료하였다. 평균 치료 기간은 5.8 $({\pm}4.0)$일이었다. 24명의 환자에서 재원 기간이 길어졌으며, 의인성 기흉으로 인한 사망은 없었다. 결론: 이 연구에서는 의인성 기흉의 가장 흔한 원인은 경피적 폐생검이었다. 이에 따른 사망률이나 이환율은 미미한 수준이었다. 의인성 기흉의 진단에 있어 침습적인 시술 이후의 신중한 검사 및 그에 따른 치료가 중요할 것으로 생각된다.