• The Journal of Pediatrics of Korean Medicine
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• v.18 no.1
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• pp.179-191
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• 2004

Objective: The aim of this study was to investigate enuretic children attending oriental hospital and classify subtypes and evaluate possible factors that enhance or hamper of continence. Methods: Children attending kyeongju dongguk oriental hospital pediatrics between January 2000 and December 2003 with chief complaint of nocturnal enuresis were enrolled. The data of present symptoms and improvement progress was collected via telephone interviews with their parents. Results: The total number of children was 61. 32 of them were male and 29 female. Sex ratio was 1.1:1. Patient under 6 years of age was 68.8%. Using acupuncture, acupressure or chimsband with herb medicine, treatment frequency was increased. Patients with nocturnal enuresis(NE) was 48, and primary nocturnal enuresis(PNE) 39, secondary (SNE) 9. 13 was impossible to diagnose. The ratio of male to female was 1:1.09. PNE was 4 times as many as SNE. Male was predominent in PNE, and female in SNE. In the progress of PNE, male and female were similiar. but SNE, male was all cured, female remained 50%. And elapsed time of male to improve was longer than that of female. In the progress of improvement, many parents mentioned that their child was improved spontaneously regardless of subtype. Conclusion: We consider age, sex distinction, subtype, bladder symptoms, frequency, time of progress as influencing factor of prognosis, but failed to verify significance. To develop guideline of NE and find influencing factor of prognosis, more prospective study through taking history carefully and using questionnaire is needed.

• The Journal of Pediatrics of Korean Medicine
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• v.18 no.1
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• pp.273-288
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• 2004

Objective: The purpose of this study was to investigate the oriental cause and treatment of the polyhidrosis of hands and feet. Methods: It was studied 47 kinds of Oriental Medical literature for polyhidrosis of hands and feet Results: Polyhidrosis of hands and feet due to lowered superficial resistance brought on by deficiency of qi. Main pathogenesis(病因病機) is the heat in the middle energizer(中焦熱) such as heat in the stomach(胃熱) and the spleen and stomach heat stagnation(脾胃積熱), deficient in Yin and Yang, qi and blood(陰陽氣血), and retention of undigested food(食積) due to improper diet(飮食不能). Treating method(治法) is eliminating dampness and regulating the stomach(淸熱燥瀑和中), invigorating, replenishing spleen qi(補益脾氣), and nourishing the stomach Yin(滋養胃陰). Treating prescription(治方) is presented as Palmultang with Additional Ingredients Rhi.zoma Pinelliae, Pona for principle drug Rhi.zorm Typfwnii Radix Aconiti for adjuvant and messenger drug(八物湯加半夏 茯笭君 白附子 川烏爲在使), Daeshihotang(大柴胡湯), Cheongbisan(淸脾散), Moryeosan(牡蠣散) etc. The external treatments(外用法) are described as ways of washing hand and foot after steaming with boiled Decoction(牡蠣散) of AJurnen(白礬); Radix Puerariae(乾葛), Radix Astragali(黃?); Radix Puerariae(乾葛), Herba Schiwnepetae(荊芥); Radix Saposhnikoviae (防風), 白礬(AIumen). The acupuncture recipes (鍼治療法) are the toninfication(補) of Buryu(KI 7)(復溜) ; Eumgeuk(HT 6)(陰?), tonification(補) methods of Buryu(KI 7)(復溜) ; Gihae(CC 6)(氣海) and reduction(潟) of Hapgok(LI 4)(合谷), the reduction(潟) of Hapgok(LI 4)(合谷), tonification of Buryu(Kl 7)(復溜), reduction(潟) of Jigu(TE 6)(支溝) ; Taechung(LR 3)(太衝) ; Yangneungcheon (GB 34)(陽陸泉). and selection of points of Hapgok(Li 4) (合谷) and Nogung(PC 8)(勞宮). The Tui-na therapies (推拿療法) are removing heat from the stomach meridian(淸胃經O) and so on.

• The Journal of Pediatrics of Korean Medicine
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• v.18 no.1
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• pp.1-9
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• 2004

Objectives: The purpose of this study was clinical review of pediatric patients with fracture that visited oriental medicine center. Methods: In retrospective study, the pediatric patients, who were visited to oriental medicine center due to fracture, were classified by sex, age, fracture site, date of accident, injury mechanism, time of treatment, kind of treatment. Results and Conclusion: Total 32 patients were visited due to fracture from April 2001 to March 2004. Male Patients were 27, female were 5. In distribution of age, 10 year-old and 11 year-old were 40.7% of totality. In distribution of month, May was 10(31.3%), June was 6(18.8%), and March was 4(12.5%). There are more patients with fracture in spring than other season. In distribution of fracture site, foot was 15(46.9%), hand was 7(21.9%), ankle was 4(12.5%), upper extremity was 3(9.4%), clavicle was 2(6.3%), tibia was 1(3.1%). In distribution of injury mechanism, slip down was 23(71.9%), impaction 5(15.6%), fall down 3(19.4%), crushing injury 1(13.1%). In distribution of injury motive, soccer was 8(25.0%), basketball 4(12.5%), skating 3(9.4%), cycling 2(6.3%), sliding 1(3.1%), Tae-kwon-do 1(3.1%), other sports 5(15.6%), collision 1(3.1%), walking 2(6.3%), hit 3(9.4%), etc. 2(6.3%). In distribution of treatment account, one time was 23(71.9%), twice 3(9.4%), three times 2(6.3%), four times 2(6.3%), five times 2(6.3%). In distribution of treatment time, 1 week was 26(81.3%), 2 weeks 4(12.5%), 3 weeks 2(6.3%). In distribution of treatment kind, acupuncture treatment was 18(56.3%), negative cupping 7(21.9%), splint 13(40.6%), and other treatment(coban taping, medical patch, and so on) 5(15.6%), transfer 14(43.8%).

• The Journal of Internal Korean Medicine
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• v.25 no.2
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• pp.335-343
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• 2004

The two case reports here presented are based on an inpatient with lateral medullary infarction, known as Wallenberg's syndrome with chief complains of central dizziness and cerebellar ataxia, and an inpatient with infarctions of cerebellar, pontine, and lacunar thalamic region. QSCCII was performed while the patient was hospitalized and, by consultation with the Dept. of Sasang Constitutional Medicine, the patient was diagnosed with Taeumin. Thus, an oriental medical therapy of Cheongsimyeonjatang, acupuncture, and moxibustion was carried out. As a result the degree of dizziness decreased noticeably while other symptoms improved as well. Before leaving the hospital, the degree of cerebellar ataxia also improved and the patient was able to go on foot by himself. In conclusion, significant improvements were observed in cerebellar and a pontine infarction patients who suffered central dizziness and cerebellar ataxia through Sasang medical therapy.

• The Journal of Internal Korean Medicine
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• v.32 no.3
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• pp.435-443
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• 2011

Fahr disease (FD) is a rare neurological disorder characterized by presence of abnormal and associated cell loss in certain areas of the brain, mostly in basal ganglia, thalamus, cerebellum and subcortical areas. Approximately two-thirds of the patients are symptomatic. The most common neurological manifestations include movement disorders, cognitive impairment, cerebellar signs and speech disorders. We report one case of estimated FD through brain computed tomography (bilateral calcifications of basal ganglia, thalamus, centrum semiovale, subcortical white matter of occipital lobes, cerebellum). At the first time of treatment, he complained of tremors in his upper limbs. We diagnosed the patient as deficiency of qi (氣) and movement of phlegm-heat-wind (痰熱風動) type according to symptoms and treated by herbs and acupuncture of oriental medicine. During treatments, we evaluated how well the oriental medical treatments were working using visual analogue scale (VAS) and amplitude of hands. After the oriental medical treatments about tremor, VAS dropped from 10 to 2 and amplitude of hands from 20 mm to 2 mm, but the ratio of brain calcifications was not changed. This study suggests that oriental medical treatments can be applicable to improve FD.

• The Journal of Internal Korean Medicine
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• v.30 no.4
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• pp.732-745
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• 2009

Objectives : This study analyzed the contents of research papers of complementary and alternative medicine (CAM) concerning chronic obstructive pulmonary disease (COPD) published in PubMed during the last 5 years. This study was conducted to help clinical studies for treating COPD with Oriental medicine. Materials and Methods : We inspected 31 theses and scrutinized their objectives, periods, participants, materials and methods, methods of assessment, results and Jadad score. Results : The treatments in the studies were supplements, physical training, acupuncture, acu-TENS, Bojungikgi-tang (Buzhongyiqi-tang), counseling, breathing training, osteopathic manipulative treatment, reflexology, and distractive auditory stimuli. The aims of treatment were improvement of exercise capacity, lung function, quality of life, oxidative status, nutrient status, systemic inflammation, and cessation of smoking. The median for treatment period of study was 8 weeks, the median number of participants was 35 and the differences between mean $FEV_1$ from groups were less than 10% in 22 studies. The methods of assessment were lung function test, exercise capacity test, muscle strength test, questionnaire of QoL, laboratory studies, and measurement of nutrient state. The mean of Jadad score was $2.4\;{\pm}\;1.03$, and 24 treatment were assessed as effective. Conclusion : Recent CAM studies of COPD have focused on various topics in alternative and complementary medicine, and it is necessary to provide objective studies for treatment of this disease with Oriental medicines.

• The Journal of Internal Korean Medicine
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• v.35 no.2
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• pp.195-207
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• 2014

Objectives : The purpose of this study was to investigate how Rhei Radix et Rhizoma affects on insulin resistance and adipose tissue inflammatory response in high fat diet induced obese C57BL/6 mice. Methods : Obesity was induced in C57BL/6 mice by high fat diet for 12 weeks. Models were divided into 3 groups (n=6) of normal diet, high fat diet (HFD), and high fat diet with Rhei Radix et Rhizoma and investigated for 12 weeks. We measured body weight, FBS and oral glucose tolerance test (OGTT), serum insulin, homeostatic model assessment-insulin resistance (HOMA-IR), weight of liver and epididymal fat pad. Inflammatory markers such as adipose tissue macrophage (ATM), tumor necrosis factor-${\alpha}$ and interlukin-10 and CD68 of epididymal adipocyte were determined to evaluate the effect of Rhei Radix et Rhizoma on adipose tissue inflammation. Results : Compared with the HFD group, we observed loss of body weight and epididymal fat pad weight, improvement of glucose level and HOMA-IR, reduction of ATM and gene expression of TNF-${\alpha}$, CD68 in the high fat diet with Rhei Radix et Rhizoma group. Conclusions : This study suggests that Rhei Radix et Rhizoma has effects on insulin resistance and adipose tissue inflammatory response in high fat diet induced obese mice.

• The Journal of Internal Korean Medicine
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• v.39 no.3
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• pp.293-301
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• 2018

Objective: The purpose of this clinical trial is to examine the efficacy and safety of electroacupuncture on liver cirrhosis patients suffering from muscle cramps. Methods: A total of 14 liver cirrhosis patients with muscle cramps were treated by electroacupuncture three times a week for four weeks (12 times total). The electrical stimulation was a frequency of 100 Hz. Evaluation of the muscle cramps was measured by a questionnaire of subjective symptoms. The patients' condition was evaluated four times over a period of eight weeks. We also assessed the deterioration of liver disease using the Child-Pugh score and blood tests. Results: This study proves that four weeks of electroacupuncture treatment is effective in reducing the frequency of muscle cramps and that the effects of electroacupuncture treatment lasted during another four-week follow-up period after treatment. Conclusions: This study suggests that electroacupuncture treatment is beneficial for improving muscle cramps in liver cirrhosis patients (p=0.000). Electroacupuncture is thought to be a safe treatment for liver cirrhosis patients with muscle cramps without contributing to the worsening of liver function. Further study with a larger sample size is needed to confirm our findings.

• Journal of Oriental Neuropsychiatry
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• v.20 no.4
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• pp.79-89
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• 2009

Objectives : To address suitable method for designing clinical trial intervening Traditional Korean Herbal Medicine on General anxiety disorder through the recent clinical research in Chinese Herbal Medicine. Methods : Randomized, controlled trials(RCTs) of treatment of general anxiety disorder intervening herbal medicine were searched through CNKI databases. We examined several item of studies and evaluated using Jadad scale. We searched articles in CNKI with the key word "General anxiety disorder or 廣範性焦慮症", among them we selected the clinical trial studies related with herbal medicine except for case reports, studies of acupuncture therapy or west medicines. Results : 11 RCT studies of herbal medicine met inclusion criteria. The Studies used CCMD-3, HAMA as inclusion tool and mainly HAMA as a evaluation tool. Studies were progressed for 2-8 weeks, mostly used various positive control. Experiment medicine were mainly 理氣劑, 安神劑. In most studies, experiment group made similar or higher efficacy in comparison with control group. Mean Jadad score of studies was $1.3{\pm}0.67$, and only one study was double-blinded among 11 studies. Conclusions : RCT studies on general anxiety disorder of chinese herbal medicine tend to focus on investigating effect of herbal medicine through setting positive control group with CCMD-3 and HAMA. But, most studies had low quality of trial, for lack of pattern identification, evaluation and inclusion tool of chinese medicine. Clinical trials of general anxiety disorder should provide good quality by randomization, double-blinding, and multi-site trial.

• Journal of Oriental Neuropsychiatry
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• v.24 no.3
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• pp.211-228
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• 2013

Objectives : This report describes the diagnostic and therapeutic procedures of Collaborative Practice between Korean Traditional Medicine and Western Medicine for two dementia patients. Furthermore, through these cases, we suggest a model of collaborative practice between Korean traditional medicine and western medicine for the treatment of dementia. Methods : Two patients suffering from several symptoms related to dementia received collaborative practice between Korean traditional medicine and western medicine. Physicians of deparment which paient first visit interviewed patient and patient's guardians, discussed the symptoms and the status of the patient. Since then, the medical team made a differential diagnosis based on the results of brain imaging, hematology, urine test. and apprehended the status of dementia by the neuropsychological test. Korean traditional physicians examined the physical symptoms and identified the pattern of dementia in Korean traditional medicine. Following this, they decided on the method of acupuncture, moxibustion, cupping and herbal treatment. Western physicians decided on the type of medication after consideration of the patient's other medical conditions. Every intervention was decided by both Korean traditional physicians and western physicians after discussion. The medical team provided education on dementia and counseled the guardians. They also wrote the paper for using the long-term care insurance for the aged. Results : Two patients showed no improvement on the neuropsychologic and activity of daily living tests. However, the patients' subjective physical symptoms were improved. The collaborative practice between Korean traditional medicine and western medicine improved the patients' and guardians' satisfaction. Conclusions : Through these cases, we propose a model of collaborative practice between Korean traditional medicine and western medicine for dementia categorized diagnosis-test, treatment, prevention, management. More specifically, we supplement qigong and psychotherapy which was inadequate in these cases.