Purpose: These experiments were undertaken to evaluate the effect of Onpoeum on ovarian functions and differential gene expressions related with cell viabilities caspase-3, MAPK and MPG in female mice. Methods: We administered the Onpoeum to 6-week-old female ICR mice for 4, 8, or 12 days. With different concentration of Onpoeum, the female mice were injected PMSG and hCG for ovarian hyperstimulation. The mice divided into 3 different groups for each experiment. We chose the Caspase-3 for cell apoptosis, MAPK and MPG genes for cell viability and DNA repair. Results: In case of 4, 8, 12 day of Onpoeum, we were examined the mean number of total ovulated oocytes and the number of morphologically normal oocytes. We were also examined the embryonic developmental competence in vitro. In addition we were examined the differential expression of cell apoptosis, viability and DNA repair related genes, Caspase-3, MAPK and MPG according to concentration and duration of Onpoeum. From these results showed that the administration of Onpoeum played a role of prevention of cell apoptosis and DNA damages and also increased cell proliferation resulted in ovarian functions. Conclusions: It is suggested that the medication of Onpoeum may have beneficial effect on reproductive functions of female mice via prevention of cell apoptosis and DNA damaging and promotion of cell proliferation.
According to herbalogical bibligraphy and literature, therapeutic effects of Achyranthis Radix on arthritis was as follows, 1. Achyranthis Radix of Amaranthaceae is divided into five species-Achyranthes japonica, A. bidentata, A. longifolia, A. fauriei, Cyathula capitata, C. officialis and the characteristic, taste, channel entry, effects and main treatments were alike. 2. Winefrying stood for repairing treatement method for Achyranthis Radix Before repairing treatment method, Achyranthis Radix had three tastes(bitter, sour, and sweet) and calm and not poisoning characteristic. After repairing treatment method, the bitter taste was disappeared, and calm and not poisoning characteristic was changed into warm characteristic. 3. Effects of Achyranthis Radix were quicking the blood and dispelling stasis, liver-kidney supplement and strengthening musculo-skeletal system. Main treatments were relief of lumbar and knee joint pain, static menstrural block and wind-cold- damp impediment. 4. Contraindication of Achyranthis Radix was sympthom caused by spleen-kidney yang vacuity, upper burner disease and lower burner hemorrhage etc. Being used in pregnant woman, it could incur abortion. 5. Contraindication of Achyranthis Radix was beef, milk and mutton. It's fear was Radix Cynanchi Stauntonii and Semen Plantaginis. It's aversion was the firefly. Herba Taraxaci, Carapax Amydae, Carapax Testudinis and Radix Cynanchi Stauntonii. From above results, I suppose Achyranthis Radix has enough herbalogical foundation and could be used to treat arthritis and it is necessary to make a profound study of it.
This study has been carried out to investigate the cause, pathological mechanism and treatment of CVA in Youmunsachin(儒門事親), written by Changjongjung(張從政) The results were follows : 1. The cause of CVA in Youmunsachin(儒門事親) was quotated from the theory of Naekyung(內經), Guel-eum-pung-mok(厥陰風木) and exogenous wind evil(外感風邪) on weakness of human body. 2. The pathological mechenism of CVA was that flows of Ki(氣) were obstructive, or executive heart(心) suppress lung(肺) and weakened lung(金) did not control liver(肝), executive liver brought to Gan-pung-nae-dong(肝風內動), and he thought that onset of CVA was frequent in 3nd, 4th, 9th. 10th, 12th lunar month. 3. In treatment of CVA, Han-to-ha-bub(汗吐不法, sweating vomiting passing stool method to remove evil) was used. His treatment was divided into ten sweating vomiting passing stool method by medication for internal use, one vomiting method by medication for external use and one sweating method by using acupuncture. 4. In treatment of CVA, when emergency time, vomiting and passing stool method were used, and then, method of Yangheulgeopung(養血祛風), Chungeulgeodam(淸熱去痰), Pyorissanghae(表裏雙解), Whalheultonglak(活血通絡) was used. 5. In the form of prescription, he used the form of Hwan, San(丸, 散), and he used toxic agent frequently.
Chest pain is classified into two major categories of cardiac chest pain and non-cardiac chest pain. Cardiac chest pain is caused by cardiovascular disease, for example, myocardial infarction, angina pectoris, valvular heart disease, cardiac enlargement or hypertrophy, dissecting aortic aneurysm, pericarditis, myocarditis, etc. When the chest pain is not attributed to heart disease, it is termed non-cardiac chest pain. Non-cardiac chest pain is caused by pulmonary, gastrointestinal, musculoskeletal disease, psychiatric factor, etc. In tills case, we treated a 54-year old female patient who was diagnosed with dilated cardiomyopathy and suspicious sick sinus syndrome. She complained of chest pain, exertional dyspnea, dizziness and headache. For treatment, we made use of Yugultangami(六鬱湯加味) and Daejobwan(大造丸). Before and after treatment, we measured Heart rate variability(HRV). In result, the clinical symptoms were improved and there was a significant increase in assessmeut by Heart rate variability(HRV). Tills result suggests that Yugultaugami aud Daejowhan have a good effect on cardiac chest pain.
This study carried out to investigate consciousness level and situation of treatment by acupuntury (the most important part of oriental medicine) and analyze factors affection to the praetice of exercise. The main purpose of the study was to give basic and necessery data in formulating a policy related to Oriental Medical Treatment. The study was conducted by trained surveyers, for dueller in three cities (Seoul, Busan and Taegu) during 1990. 1. 4 -1990. 1. 23. The result of this study can be summerized as follows. 1. The subject of criticism an investigation for general charactristic be conducted in seoul, Busan and Taegu city area an objective 417 person, 423 person, and 366 person was among those comparatively little more by male was higher rate than female. Those in classification age group evaluation was adopted by age group 10, 20 years old adult 41.3% of most higher rate, next rank was adopted by age group 40 years old (24.9%). 2. An objective of investigation survery was made to personnel were comparative an educated level significantly higher such as college graduated 48.8%, high school graduated 30.1%. And the native comes from urban area, rural, midium and small city rate were shown as 29.6%, 28.4% and 19.9% each other. There by classification of occupational job was shown by students has 27.4% are most higher significantly also there sales and servive field job appearanced 15.1% and expert technical job is 9.0%. Religion is buddist, Christianity, Catholicism all them each other shown 33.6%, 16.7% and 12.4%. An evaluation in economic situation value rate was appearanced by middle class is 61.7% and upper and lower classes are 14.4% and 23.9% with each other and married were 59.2% 3. The people resident in cities area has experience of acupuncture were 70.4% There by classification of an area was shown by Seoul, Busan and Taegu all them other shown 59.7%, 85.2%, 68.1%. According as sex was shown by male 71.7% was more higher than female. According as age was shown by 40 years 85.0% 50 years 77% 20 years old was more higher than 30, 60 years old.
$\ll$Yongchu(靈樞)$\gg$ is completed as a result of gathering several treatises about oriental medicine in B.C. 3c ~ A.D. 1c, and esteemed as a bible of oriental medicine, especially very much quoted in acupuncture fields. But the name of $\ll$Yongchu(靈樞)$\gg$ wasn't in existence at that time. Until A.D. 3c, it had been named after $\ll$Guguen(九券)$\gg$, given it's number of volumes, and since then mainly named after $\ll$Chimgueng(針經)$\gg$, given a word of the first volume. After A.D. 6c, under the influence of Taoism(道家), it was titled $\ll$Yongchu(靈樞)$\gg$, $\ll$Guhe(九墟)$\gg$, $\ll$Gureong(九靈)$\gg$ etc. Yongchu(靈樞), guhe(九墟), gureong(九靈) are words which is connected with Taoism(道家). In 1155, Sung Sa(史崧) published $\ll$Yongchu(靈樞)$\gg$, whim became a textbook of oriental medicine, so other titles disappeared since then. $\ll$Yongchu(靈樞)$\gg$, $\ll$Guhe(九墟)$\gg$, $\ll$Gureong(九靈)$\gg$, $\ll$Guguen(九卷)$\gg$, $\ll$Chimgueng(針經)$\gg$ are not the same book, but the contents are almost similar, and some letters are different. Especially the textbook, pubished by Sasung(史崧), had been related to the $\ll$Chimgyeng(針經)$\gg$, delivered to North-Song(北宋) dynasty by Jong-Gag Haung(黃宗慤), an envoy of an ancient Korean state(918-1392). So I expect to progress the study of medical exchange about it in the future.
This book was completed in the 33rd year of Gang-hui-gapsul(康熙 甲戌) in the Cheong(淸) dynasty(1694), and was first inscribed in the 55th year of Geonryung(乾隆). In this first edition named 'Daechudangbon(大雅堂本)', his descendant Jinbonghui(陳鳳輝) wrote the postscript. There are also other editions such as 'Ga-gyeong-ganchwihyeondangbon(嘉慶間聚賢堂本)', 'Wimundanggeonsangbon(緯文堂巾箱本)' and 'Guangseo-ganseonseongdangbon(光緒間善成堂本)' Second, this book was called "Oe-gwabirok(外科秘錄)" and used the pen name 'Gibaekchunsasojeon(岐伯天師所傳)'. There are 16 volumes in total. The beginning of volume one, is a drawing of the 14 meridians. Volumes 1$\sim$4 are on the symptoms and treatment of abscesses and sores and ulcers[癰疽瘡瘍]. Volumes 5$\sim$13 are on surgery, dermatology and 156 diseases such as wounds by contusion, sharp objects and insects and beasts[跌撲, 金刃, 蟲獸傷]. Volumes 14$\sim$16 list the internal treatments, external medicine, acupuncture and moxibustion and surgery of sores and ulcers. Third, the book stressed early detection and treatment of diseases, emphasized inner resolving[內消] being cautious about using medicine, and further deepened the syndrome differentiation and treatment[辨證施治] of sores and ulcers[瘡瘍] by dividing fire toxin(火毒) into Eumhwa and Yanghwa(陰火/陽火). Also, it established the cause of sores and ulcers development as the deficiency of Gi(氣) and blood[血] and focused especially on the liver and kidney's involvement in the process. It also asserted that the pathogen[邪] is the tip[標], so one should eliminate and reinforce[攻補] to balance it out. The sore and ulcer surgery[瘡瘍外科] part is mostly based on detoxifying[解毒] and resolving[消散]. Although the meridians were mentioned, they were not emphasized, while moxibustion treatment of sores and ulcers[瘡瘍] were thoroughly analyzed. Also, of all 550 formulas in this book, 90% are experience-based which frequently use Geum-eunhwa(金銀花), Pogong-yeong(蒲公英) and Jahwajijeong(紫花地丁). The usages are unique, and the formulas have good adaptability. The symptoms of the diseases are explained first, followed by according main and sub treatments.
Objectives : The comparison of symptoms of hypoadrenocorticism with symptoms according to spleen and kidney show how many points of similarity they are. And by analysis of symptoms of hypoadrenocorticism it was examined that Kidney Jeonggyeok help to cure many different symptoms including symptoms of hypoadrenocorticism. Methods : The symptoms of hypoadrenocorticism were compared and analyzed according to standards of the book of korean traditional medical pathology. First, this study was designed to show to found out how many symptoms of hypoadrenocorticism belong to symptoms of kidney qi-deficiency and slpeen qi-deficiency and how similar they are. Second, the symptoms of kidney qi deficiency were compared with the indicant of kidney Jeonggyeok suggested by two of korean traditional doctors to find out kidney Jeonggyeok can help to cure symptoms of kidney qi deficiency. And then on the basis of those, the symptoms of hypoadrenocorticism were compared with the symptoms of kidney qi deficiency. Results : The hypoadrenocorticism seems to be kidney yang(陽) deficiency. But because hypoadrenocorticism doesn't have body temperature decline, symptoms of hypoadrenocorticism are more similar symptoms of kidney qi deficiency than symptoms of kidney yang deficiency. The symptoms of hypoadrenocorticism seems to be correlated with the functions of spleen. But because of vomiting and pigmentation(skin and mucous membrane), they seem to have less to do with the functions of spleen than the functions of kidney. The comparison analysis of indicant of Kidney Jeonggyeok and symptoms of kidney qi deficiency shows that acupuncture stimulation help to cure kidney qi deficiency and hypoadrenocorticism. Conclusions : Symptoms of hypoadrenocorticism are expected to be more similar symptoms of kidney qi deficiency. And Kidney Jeonggyeok is helpful for treatment of Kidney qi deficiency and hypoadrenocorticism.
Objectives : In order to apply useful data to clinical practice, we undertook this study and tried to find factors related with sequelae of facial palsy in relation with patients' age and gender distribution, past history with the disease, condition before onset, duration of recovery time, existence of remaining sequelae, types of the sequelae, and duration for sequelae to disappear. Methods : We evaluated patients' condition (fatigue, stress, chills, cold and so on), past history (diabetes mellitus, hypertension, stroke, herpes zoster, cancer and so on), duration of recovery time, types of the sequelae, age and sequelae distribution as to when the treatments were started as we examined 473 patients who were diagnosed with facial palsy, and visited the Out-patient Department of Acupuncture and Moxibustion of Bundang Oriental Medicine Hospital of Dongguk University through 2003 and 2004. Results : The sequelae of facial palsy were not significantly relevant to the signs found before facial palsy occurred(fatigue, stress, chills, and cold), or to patients' past history (hypertension, diabetes mellitus, facial palsy, herpes zoster). The duration of recovery time was within 30 days for 45.3% of the patients examined in this study, and within 90 days for 72.6%. Evaluating the existence of sequelae in relation to age, we found more in the group comprised of patients aged 50 and over than under 50. We found more sequelae in the group which is consisted of patients who had not been treated until 6 days after than within 5 days from the onset. Conclusion: Attention to sequelae will be needed for patients aged 50 and over and who were not treated until 6 days after the onset, as they had more sequelae.
Objectives: This study aimed to investigate the opinions of Korean medical doctors on how to elucidate possible remedial measures for expanding the health insurance benefits coverage item of Korean medicine (KM). Methods: An online survey was conducted to all members who had registered e-mail address in the association of Korean medicine from 1 to 17 November, 2016. Statistical analysis was performed and odds ratio with 95% confidence interval were calculated by each subgroup. Results: A total of 743 members answered the questions and the response rate was 4.1%. The priorities for expanding health insurance benefits were as follows: thermographic imaging, Sasang constitution typing test, and pulse wave among examinations; pharamacopuncture, embedding acupuncture, and acupotomy among procedures; Chuna manual therapy, manual therapy for meridian muscle, and Daoyin exercise therapy among manual therapies; low-frequency electrical therapy, traction, paraffin bath, and light therapy among physical therapies; and aromatherapy, enema therapy, and color therapy among activities of KM. Conclusions: It should be covered by the national health insurance (NHI) of KM that thermographic imaging, pharmacoacupuncture, Chuna manual therapy, low-frequency electrical therapy, aromatherapy as a top priority. We also suggest that basic medical tests, such as blood, urine, or imaging, should be included in the coverage of the NHI of KM. It is necessary to review the expertise and public opinions about the plans and priorities for the conversion of the desired medical services to be covered by the NHI.
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