• Microbiology and Biotechnology Letters
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• v.27 no.5
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• pp.354-358
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• 1999

In order to know the antifungal characteristics of saturated fatty acids having 6 to 12 carbons, their minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) were estimated against Saccharomyces cerevisiae. Fatty acids from C6 to C11 exhibited increasing activity with chain length, but C12 fatty acid did not show activity at all. In relation to antifungal modes of actions, fatty acids investigated showed on inhibitory activity toward the plasma membrane H+-ATPase of Saccharomyces cerevisiae. Their inhibitions to the glucose-induced acidification and ATP hydrolysis caused by the proton pump were found to be in common wiht antifungal activities. At the test concentration of 1mM, hexanoic acid (C6) showed the lowest inhibition of about 30%, while undecanoic acid(C11) showed the strongest inhibition of over 90%. In addition, as seen with antifungal activity, the inhibitory activity of dodecanoic acid (C12) was suddenly reduced to less than 50%.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.18 no.1
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• pp.97-106
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• 2011

Purpose: The purpose of this study was to identify social support and health status based on characteristics of leisure activity in middle-aged women. Methods: Participants were 148 middle-aged women living in the capital area. Data were collected through self-report questionnaires which were constructed to include leisure activity characteristics, social support and Brodman's CMI. Data were analyzed using t-test, and ANOVA, with SPSS/WIN 14.0. Results: Social support was different depending on leisure type, leisure partner, length of participation in present activity, regularity, and motivation to start activity. Health status was different depending on the length of participation in present activity, and regularity. Conclusion: Because social support and health status depend on characteristics of leisure activity, further study in nursing one how to resolve the physical, psychological, social and health problems that middle-aged women might experience through various leisure activities.

• Journal of Forest and Environmental Science
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• v.34 no.6
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• pp.490-496
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• 2018

The present study aimed to identify the importance of forest experience activity by examining what effects forest experience activity has on primary school students. The study population consisted of 108 students enrolled as fourth graders in primary schools in Chuncheon as of November 2017. The study measured the changes in their attitude toward forest and personality from before and after forest experience activity. The results indicated that the primary school students who participated in forest experience activity showed statistically significant increase in attitude toward forest and personality. In other words, the study identified the positive effects of forest experience activity on recognizing the importance of nature and personality building. The present study aimed to test the importance and effects of forest experience through forest experience activity outside of the classroom, as well as to present the validity of promoting forest experience activity.

• Physical Therapy Korea
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• v.23 no.1
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• pp.11-19
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• 2016

Background: Investigation in gender differences of kinetics and kinematics for individuals with patellar femoral pain syndrome (PFPS) was not sufficiently performed. Objects: The purpose of this study is that whether there is a difference depending on gender from muscle activity and strength and knee valgus angle during controlled single-leg squat which is widely used as clinical movement test for the patient with PFPS. Methods: 20 young adults (10 men, $20.0\pm}2.1$years; 10 women, $20.4{\pm}2.1$years) with PFPS were voluntarily recruited in this study. Muscle activity and strength and knee valgus angle were collected during single-leg squat. Independent t-test and Mann-Whitney test were used to compare the differences between groups of male and female. Results: Rectus femoris (t=-2.204, p=.041) and vastus medialis oblique (t=-2.151, p=.045) muscle activity of women were significantly higher than male group. Normalized muscle strength of hip and knee muscles showed a significant difference between men and women (p<.05). Valgus angle of the knee in women (t=-2.450, p=.025) were increased significantly than men. Conclusion: The therapist would consider the characteristics of these gender differences during performing movement test, exercise, and education for the individuals with PFPS.

• Natural Product Sciences
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• v.4 no.2
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• pp.105-114
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• 1998

The antimutagenic activity of a methanol extract of Ecklonia stolonifera (Laminariaceae) against aflatoxin $B_1\;(AFB_1)$ was demonstrated with the Salmonella typhimurium assay. The numbers of revertants per plate decreased significantly when this extract was added to the assay system using S. Salmonella typhimurium TA100. The methanol extract also exhibited significant inhibitory effects on the micronuclei formation in mouse peripheral blood reticulocytes and the DNA damage in mouse spleen lymphocytes induced by N-methyl-N-nitrosourea (MMU) and benzo(a)pyrene (B(a)P). The MeOH extract was then sequentially partitioned with $CH_2Cl_2,\;CH_2Cl_2$ insoluble intermediate, EtOAc, n-BuOH, and $H_2O$. All fractions possessed antimutagenic activity but the $H_2O$ fraction was inactive. Among active fractions, the EtOAc and $CH_2Cl_2$ insoluble intermediate fractions showed the highest activity. Column chromatography using $SiO_2$ and Sephadex LH-20 yielded phloroglucinol from the EtOAc fraction. Phloroglucinol also demonstrated significant antimutagenic activity, and inhibitory effects on the micronuclei formation in mouse peripheral blood reticulocytes and DNA damage in mouse spleen lymphocytes induced by MMU and B(a)P.

• Journal of Korean society of Dental Hygiene
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• v.17 no.2
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• pp.283-294
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• 2017

Objectives: The purpose of the study was to investigate the effect of calcium concentration in saliva on dental caries activity after consuming calcium. Methods: A total of 59 adult women aged 20 to 40 years were surveyed for calcium intake. The daily average calcium intake was analyzed through dietary records of the subjects. The subjects were divided into two groups based on daily average calcium intake. Salivary pH and concentrations of minerals in the saliva were obtained from A group and B group. Calcium ($Ca^{2+}$) and magnesium ($Mg^{2+}$) concentrations in saliva were measured by HPLC-Ion chromatography using 15 mM sulfuric acid. The dental caries activity test was quantified by salivary buffer capacity test and plaque pH test. Results: The mean $Ca^{2+}$ concentrations of A group was $12.75{\mu}g/m$, the mean $Ca^{2+}$ concentrations in the B group was $16.30{\mu}g/mL$ (p<0.05) and respectively, $Mg^{2+}$ concentrations were found to be $0.48{\mu}g/mL$ and $0.51{\mu}g/mL$. Calcium intake and calcium concentration in saliva showed a significant correlation (r=0.380). Conclusions: The mean $Ca^{2+}$ concentrations in saliva was higher in the high calcium intake group. Therefore, calcium intake in saliva was correlated with dental caries.

• Journal of the Korean Society of Earth Science Education
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• v.5 no.1
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• pp.95-104
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• 2012

The purpose of this study is to examine what effects the experiment class to stress discussion of small groups in scientific experiment class of the elementary school has on scientific achievement and attitude on the science of the students comparing to the usual scientific experiment class. For that purpose, this study has divided 49 students at the 6th grade of the M elementary school in P City into test groups of 24 students and control groups of 25 students. Classes have been progressed by giving sufficient time to the test groups for discussion by each small groups after experiment while by allowing the control groups to finish the experiment with arrangement of the experiment results. Conclusions of this study include: First, the more familiar the experiment materials are and the easier the experiment procedures are to be operated by the students, the more actively the small group discussion activities have been deployed. It shows that the students need a certain level of background knowledge before experiment for vital discussing activities. Second, it is appeared that the test groups given the scientific experiment class stressing small group discussing activity have significantly high scores comparing to the control groups given the existing scientific experiment class. It shows that the small group discussing activities have effects on promoting understanding of the students on the scientific achievement for the scientific experiment class. Third, it is appeared that the test groups given the scientific experiment class stressing small group discussing activity significantly high scores on attitude about the science comparing to the control groups given the existing scientific experiment class. It is considered that the students could have opportunities to compare their own thoughts with others and to have reflective thought to change their thoughts through the small group discussing activity. As shown above, it shows that the experiment class to stress discussing activities is more effective to increase scientific achievement and attitude about the science than the scientific experiment class to get and arrange the experiment results from the existing experiment classes.

• Korean Journal of Human Ecology
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• v.1 no.1
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• pp.103-112
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• 1998

Cotton fabric was treated with chitosan by pad-dry(-cure) method to impart antimicrobial properties. Four chitosans of different degree of deacetylation (DAC: 65~95%) with similar molecular weight(MW: ca. 50, 000) and one chitosan oligomer(MW 1, 800, DAC 86%) were used. In order to improve the durability to laundering of antimicrobial activity for the fabrics treated with chitosan oligomer, crosslinker or binder was included in the finishing formulation. Antimicrobial activity against Staphylococcus aureus and Proteus vulgaris was evaluated by the Shake Flask Method. The treated fabrics were laundered up to 20 times according to AATCC Test Method 60-1986 or JIS 0217-104 and antimicrobial activity of the laundered fabrics was evaluated. The antimicrobial activity was increased with the increase of concentration and degree of deacetylation of chitosan. And the cured fabrics showed better durability to laundering than the not-cured fabrics according to AATCC Test Method 60-1986. Crosslinker and binder decreased antimicrobial according of the fabrics treated with chitosan oligomer and were not effective to improve the durability to laundering according to JIS 0217-104. (Korean J Human Ecology 1(1) : 103~112, 1998)

• Journal of the Korean Home Economics Association
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• v.42 no.3
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• pp.145-158
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• 2004

Experimental conditions for evaluating chitosan antibacterial activities were established. The chitosan antibacterial activities were measured against the Staphylococcus aureus and evaluated for their application to antibacterial textile finishing. The strain of Staphylococcus aureus used in this experiments was KCTC 1916. The chitosan antibacterial activities were estimated from the bacterial densities or ％reduction of bacteria in chitosan solutions and bacterial culture mixtures after incubation under specific conditions. Six parameters as follows were evaluated to optimize the experimental conditions for measuring antibacterial activities. The different combinations of mixtures according to the different ratios of chitosan solutions to the bacterial cultures showed different antibacterial activities. However, the chitosan antibacterial activities could be evaluated by comparing the data obtained from the same combinations of mixtures. The solvent influence on the chitosan solution antibacterial activities could be eliminated using control solution containing the same concentration of acetic acid. The initial pH of the chitosan -bacterial mixtures also affected the chitosan antibacterial activity; at a higher pH, higher activity in terms of ％reduction of bacteria was observed. In case of the bacterial solution without either the acetic acid or chitosan, the initial pH of the solution did not significantly affect bacterial growth. The ％ reduction of bacteria increased when contact times of bacteria with chitosan in the chitosan -bacterial mixture were expended upto 24 hours. However, the chitosan antibacterial activities could be successfully evaluated at contact time 0 where the chitosan-bacterial mixture was plated immediately after mixing and incubated to measure the bacterial number to 24 hours. Evaluating ％reduction of bacteria in the test mixtures after incubation were not changed when the inoculated bacterial concentrations were 2.3${\times}$10$\^$0/ml to 2.3${\times}$10$\^$6/ml. The optimal range of incubation time of the petri-Dish after plating the chitosan-bacterial mixture was 24 to 72 hours depending on the antibacterial activities of the test solutions.

• Journal of The Korean Association For Science Education
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• v.43 no.1
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• pp.29-36
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• 2023

This study investigates the effects of the operation of science activity program on scientific literacy focusing on science cultural literacy and core competencies for pre-service teachers. 255 pre-service teachers of K University participated, and the effects of the program were examined through a paired-sample t-test with one group pretest-posttest design for science cultural literacy. Only the post-test was conducted on core competency growth perception, and differences in growth perceptions by competency were compared using ANOVA. As a result of the study, the average of pre-service teachers was higher than the pre-test for science culture literacy, and this difference was statistically significant (p<.05). In the core competency growth perception, 70.6% of pre-service teachers reported growth in scientific communication ability, and as a result of the post-hoc test using LSD, it shows statistically significant growth compared to other competencies (p<.05). Through this, it was possible to confirm the educational value of the science activity program as a way to develop pre-service teachers' scientific literacy.