• Title/Summary/Keyword: Activity Support

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Programs of Activities and Services of the Adult Day Care Center for the Elderly with Alzheimer's Disease and Dementia in the U.S.A (치매나 알츠하이머 환자를 위한 주간보호시설의 프로그램에 관한 미국사례 연구)

  • 곽인숙
    • Journal of the Korean Home Economics Association
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    • v.40 no.10
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    • pp.123-139
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    • 2002
  • The purpose of this study was to understand the adult day care center as a place for the elders and adults and to develop an initial understanding of the services and activity programs for adult day care for the cognitively-impaired in the U.S.A. The data were collected from 12 Adult Day Care Centers(ADC) from 2001 to 2002 by personal interview and the documents about the programs. ADC programs provided primarily social, recreational, and health activities and services in a group setting. Centers offered participants to socialize, enjoy peer support, and receive health and social services in a stimulating and supportive environment that promotes better physical and mental health. For this purpose those centers offered not only professional health care, occupational.speech.physical therapies but also socio-recreation and therapeutic-recreation services.

A Research on the Korea Interoperability Management Model Independent of Interoperability Levels (상호운용성 수준에 독립적인 한국형 상호운용성 관리 모델 연구)

  • Cheon, Jae-Young
    • Journal of the Korea Institute of Military Science and Technology
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    • v.15 no.4
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    • pp.467-474
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    • 2012
  • One of the interoperability management activity in Korean military is interoperability level assessment. The concept of interoperability levels causes the assessed result to be uncertain and unreliable, despite the activity contributes to secure interoperability requirements of systems consistently. In this paper, I suggest Korea Interoperability Management(KIM) model which is independent of interoperability levels especially specified in LISI model, in order to support more practical and reliable interoperability management.

Inhibitory Effects of the Korean Red Ginseng Extract on the Content of Neurotransmitter-Related Components of the Mouse Brain in Convulsion-induced Model

  • Choi, Jong-Won;Yoo, Yeong-Min;Park, Hee-Juhn
    • Natural Product Sciences
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    • v.13 no.4
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    • pp.384-389
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    • 2007
  • Treatment of mice with Korean Red Ginseng (KRG) changed glutamic acid and GABA content in the mouse brain tissue with pentylenetetrazole (PTZ)-induced convulsion. KRG were orally administered at a dose of 50, 100 mg/kg for two weeks. The electroconvulsions (MES) and PTZ-induced convulsion were reduced but those induced by strychnine, bicuculine and picrotoxin were not. PTZ-induced convulsion decreased the $\~{a}$-aminobutyric acid (GABA) content in brain compared to control group while the content was increased in KRG-treated group compared to PTZ group. In the PTZ-treated group, the GABA-transaminase (GABA-T) activity was increased by 59.6%, while no effect was observed on glutamate decarboxylase (GAD) activity. These results support that the KRG decreased the GABA contents and modulated the glutamic acid contents in the brain.

Modulation of Anticarcinogenic Enzyme and Plasma Testosterone Level in Male Mouse Fed Leek-Supplemented Diet (부추 첨가 식이가 수컷 생쥐의 암예방 효소계 및 혈중 웅성호르몬 농도에 미치는 영향)

  • 김정상;곽연주;전희정;이민자;권태완
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.5
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    • pp.968-972
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    • 1998
  • Allium tuberosum Rotter(Liliaceae) is a perennial herb of which leaves are used for food. Leek has been reported to have pharmacological effects including alleviations of abdominal pain, diarrhea, hematemesis, snakebite, and asthma. To investigate the effect of dietary leek supplementation on the drug-metaboizing enzymes, quinone reductase(QR) and arylhydrocarbon hydroxylase(AHH) activities in the liver, stomach, small intestine and lung, and on the plasma testosterone and dihydrosterone hormone levels, mice were fed 2% and 5% leek diets for 8 weeks. Quinone reductase, an anticarcinogenic enzyme, was significantly induced in stomach, small intestine, and lung but slightly lowered in hepatic tissue in the experimental groups compared to control group. Arylhydrocarbon hydroxylase activity, involved in bioactivation of procarcinogens, was significantly decreased in liver and lung. Leek feeding led to the reduction in the plasma level of dihydrotestosterone which is associated with the incidence of prostate cancer. These findings support the potential chemopreventive activity of leek supplementation.

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A Structure-Based Activation Model of Phenol-Receptor Protein Interactions

  • 이경희
    • Bulletin of the Korean Chemical Society
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    • v.18 no.1
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    • pp.18-23
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    • 1997
  • Data from structure/activity studies in vir gene induction system have led to evaluate the working hypothesis of interaction between phenolic inducers and phenol binding proteins. The primary specificity in the association of a phenolic inducer with its receptor in our system is hypothesized to be the hydrogen bonding interactions through the ortho methoxy substituents as well as the proton transfer between the inducer and the binding protein. In this paper the proposed working model for phenol-mediating signal transduction was evaluated in several ways. The importance of the general acid-base catalysis was first addressed by the presence of an acidic residue and a basic residue in the phenol binding protein. Series of compounds were tested for vir gene expression activity to confirm the generation of a strong nucleophile by an acidic residue and an involvement of a basic residue as a proton acceptor. An attempt was made to correlate the pKa values of the phenolic compounds with vir gene induction activities as inducers to further support the proposed proton transfer mechanism. Finally, it was also observed that the regioselectively attached methoxy group on phenol compounds is required as the proper hydrogen bond acceptor.

$Ni/\gamma -Al_2O_3$ Catalyst Prepared by Liquid Phase Oxidation for Carbon Dioxide Reforming of Methane

  • 정경수;조병율;이호인
    • Bulletin of the Korean Chemical Society
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    • v.20 no.1
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    • pp.89-94
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    • 1999
  • Carbon dioxide reforming of methane on Ni/γ-Al2O3 catalyst was studied. A new 10 wt% Ni/γ-Al2O3 catalyst prepared by the liquid phase oxidation method (L10O) exhibited much higher activity as well as resistances to both sintering and coke formation during the reaction than the catalyst prepared by the conventional impregnation method (D10). The electrically strong attractive interaction between nickel and support during the liquid phase oxidation process and the resultant high nickel dispersion made the L10 have superior activity and stability to the D10. To elucidate the results, the experiments with nickel catalysts on the other supports as well as 7-AI203 were performed. The effect of sodium as a promoter was also studied.

Cyclohexane Oxidations by an Iron-Palladium Bicatalytic System; Soluble Catalysts and Polymer Supported Catalysts

  • Jun, Gi Won;Sim, Eun Gyeong;Park, Sang Eon;Lee, Gyu Wan
    • Bulletin of the Korean Chemical Society
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    • v.16 no.5
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    • pp.398-400
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    • 1995
  • Selective oxidation of cyclohexane in acetone solution has been studied using iron catalysts with hydrogen peroxide in-situ produced by palladium catalyst. Iron tetraphenylporphyrin chloride shows the highest activity among the tested chlorides and porphyrin complexes of some metals of the first transiton series. Iron chloride and iron tetraphenylporphyrin chloride were supported on four kinds of 4-vinylpyridine copolymer with styrene or divinyl-benzene. Nitrogen 1s photoelectron spectra give the evidence that pyridyl nitrogens of the 4-vinyl pyridine copolymer act as ligands to bind iron species. The copolymer with styrene is the most efficient support for the binding because its solubility in catalyst preparation solvent (methylene chloride) gives the pyridyl group advantage to contact with the iron catalysts. However, better catalytic activity per iron atom could be obtained with a rigid crosslinked polymer due to active site isolation.

The Effect of SNS Prosumer Activity Characteristics and Relationship Quality on User Satisfaction and Loyalty Intention (SNS 프로슈머활동 특성과 관계품질이 이용자만족과 충성의도에 미치는 영향)

  • Kwon, Do-Hee;Cho, Chul-Ho
    • Journal of Korean Society for Quality Management
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    • v.47 no.1
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    • pp.125-138
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    • 2019
  • Purpose: The present research was designed to explore a causal relationship among SNS prosumer characteristics, relationship quality, user satisfaction, and loyalty intention, and we intended to explore mediating role of relationship quality in the causal relationship. Methods: As survey tool, questionnaire that had obtained validity and reliability through literature survey and pretest survey, and sample 214 was analyzed using SEM analysis method. Results: All theoretical relationships, except the relationship between information provision and relational quality, proved to be significant. The relationship quality plays an important intermediary role in the research model. Conclusion: The characteristics of SNS prosumer activity can be summarized by interaction and informational provision. To increase user satisfaction and loyalty, it is necessary to support these characteristics and strengthen relationships with customers.

Inositol 1,4,5-Trisphosphate-induced Increase in $Ca^{2+}-ATPase$ Activity in the Microsomes of Tracheal Epithelial Cells

  • Cho, Hyoung-Jin;Park, Sung-Shin;Kim, Young-Kee
    • The Korean Journal of Physiology
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    • v.29 no.2
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    • pp.269-277
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    • 1995
  • Membrane vesicles were prepared by differential centrifugation from epithelial cells of porcine trachea. Total activity of microsomal ATPases was measured spectrophotometrically by a coupled enzyme assay. The steady-state activity of the enzyme was $329{\pm}10$ nmol/min mg protein. Thapsigargin, a specific antagonist of intracellular $Ca^{2+}-ATPase$, inhibited about 50% of the activity, leaving $178{\pm}18\;nmol/min .mg$ protein (n=6), indicating that the $Ca^{2+}-ATPase$ is one of the major microsomal ATPases. The microsomes used in this study appeared to be tight-sealed vesicles since they showed saturation in $^{45}Ca^{2+}$ uptake experiments. Inositol 1,4,5-trisphosphate $InsP_{3}, 4\;{\mu}M$, an agonist of $InsP_{3}$-sensitive $Ca^{2+}$ release channel ($InsP_{3}$, receptor), and Ca-ionophore A23187 $(10\;{\mu}M)$ induced $^{45}Ca^{2+}$ releases of 20% and 50% of stored $^{45}Ca^{2+}$, respectively. The addition of $(10\;{\mu}M\;InsP_{3}$ also increased the microsomal ATPase activity from $282{\pm}8$ nmol/min mg protein to $334{\pm}21$ nmol/min . mg protein in the intact vesicles. Similar increase in the activity was observed by making microsomes leaky (uncoupling) using the Ca-ionophore A23187. ;$InsP_{3}-induced$ effects were blocked by either thapsigargin or heparin suggesting that: 1) the $InsP_{3}-induced$ increase in ATPase activity is mediated by microsomal $Ca^{2+}-ATPase$, and 2) dissipation of $Ca^{2+}$ gradient across the microsomal membrane is responsible for the $InsP_{3}-induced$ effect. In order to test the dependence of the $Ca^{2+}-ATPase$ activity on the activity of $InsP_{3}-induced$ the activity of ATPases was monitored in various concentrations of free $Ca^{2+}$ using $EGTA-Ca^{2+}$ buffers. The $Ca^{2+}$-dependent biphasic change is the well-known character of $InsP_{3} receptor but not of microsomal $Ca^{2+}-ATPase$ in non-excitable cells; however, the activity of microsomal ATPase appeared biphasic and a maxim진 activity of $397{\pm}36nmol/min\;.mg$ protein was obtained in the solution containing 100 nM free $Ca^{2+}$. Below or above this concentration, the activity of ATPases was lower. These results strongly support a positive correlation of microsomal $Ca^{2+}-ATPase$ to the $InsP_{3}$ receptors in epithelial microsomes.

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