• Journal of Digital Convergence
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• v.5 no.1
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• pp.55-68
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• 2007

It soaks but 2001 July information communication base step law enforcement and the Enforcement Ordinance are published to follow, in order to support the establishment of evaluation and protective measure in order the vulnerability analysis against the facility of the agency which manages an important information communication base hour opinion to designate information protection specialty enterprise. As information protection specialty enterprise being revealed evacuation laboratory back 12 enterprises from information communication department become designation as the consulting enterprise and they do an enterprise activity actively. It follows in diffusion of the IT and information reconciliation level the other side where our country belongs in the world-wide first group, the research against the disfunction plan of preparation comparison the fact that law it is come negligently all actuality. The network as it will give management coat fatal effect even at obstacle occurrence hour of instant for of case and IT facility of the cyber transactions which leads, in the future there to be to corporate management, there is a possibility the stable civil official of information Facilities for communications very seeing in the portion which is important. Present condition and important propulsion contents of information communication base step law enforcement after, against a vulnerability analysis of information protection relation field and evaluation consulting methodological application situation to sleep it researches from the dissertation which it sees consequently and it does.

• Journal of Haehwa Medicine
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• v.12 no.1
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• pp.11-26
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• 2003

Alzheimer's disease (AD) is characterized by amyloid deposition and associated loss of neunons in brain regions involved in learning and memory processes. Several causes of evidence support that the congnitive disturbance is closed associated with the deficit of cerebral acetylcholine neurotransmission, and the effect of carboxyl terminal 105 amino acid fragment (CT105) of the amyloid precursor protein (APP) on the gene expression of proinflammatory cytokines. We tested it on the scopolamine-induced amnesia model of the ICR mouse using the Morris water maze with repeated orally administration of 1st Green-Tea extract (200 mg/kg) and 2nd Green-Tea extract (200 mg/kg). The Green-Tea prevents impairment of learning and memory and neuronal loss in mouse models of cognitive disturbance and it demonstrated selectivity for inhibition of acetylcholinesterase (AChE). Furthermore, the repeated administration of Green-Tea, CT105-induced alzheimer's mouse model showed central cholinergic activity by ameliorates learning and memory impairment, and isolation of CD14 microglia showed significantly decreases intracellular release of the proinflammatory cytokines tumor necrosis factor-${\alpha}$, interleukin-$1{\beta}$ and reactive oxygen species (ROS). Because of its composite profile, oral therapeutic index and a prophylactic, Green-Tea is considered the better therapeutic candidate for the treatment of Alzheimer's disease.

• BMB Reports
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• v.35 no.2
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• pp.178-185
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• 2002

The Arabidopsis thaliana S-Adenosylmethionine decarboxylase (AdoMetDC) cDNA ($GenBank^{TM}$ U63633) was cloned. Site-specific mutagenesis was performed to introduce mutations at the conserved cysteine $Cys^{50}$, $Cys^{83}$, and $Cys^{230}$, and $lys^{81}$ residues. In accordance with the human AdoMetDC, the C50A and C230A mutagenesis had minimal effect on catalytic activity, which was further supported by DTNB-mediated inactivation and reactivation. However, unlike the human AdoMetDC, the $Cys^{50}$ and $Cys^{230}$ mutants were much more thermally unstable than the wild type and other mutant AdoMetDC, suggesting the structural significance of cysteines. Furthermore, according to a circular dichroism spectrum analysis, the $Cys^{50}$ and $Cys^{230}$ mutants show a higher a-helix content and lower coiled-coil content when compared to that of wild type and the other mutant AdoMetDC. Also, the three-dimensional structure of Arabidopsis thaliana AdoMetDC could further support all of the data presented here. Summarily, we suggest that the $Cys^{50}$ and $Cys^{230}$ residues are structurally important.

• Women's Health Nursing
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• v.19 no.4
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• pp.242-253
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• 2013

Purpose: The purpose of this study was to develop a scale to assess immigrant women's needs for pregnancy and postpartum adaptation and to test the reliability and validity of the scale. Methods: To construct scale items, critical issues and difficulties associated with pregnancy and postpartum adaptation of immigrant women were identified and categorized through a literature review. Fifty-two scale items were constructed, and data for validity and reliability testing was collected with a questionnaire survey from 367 immigrant women. Data were analyzed with descriptive statistics, factor analysis, and reliability coefficients. Results: The final measurement scale to assess immigrant women's pregnancy and postpartum adaptation consisted of 48 items and 7 factors (adaptation to daily activity during pregnancy, cross-cultural understanding and personal respect, understanding of the process of pregnancy and delivery, baby rearing and family support, physical and emotional adaptation after childbirth, nutrition during pregnancy, and sexual life adaptation). The seven factors accounted for 64.26% of the variance, and Cronbach's ${\alpha}$ was .96. Conclusion: The scale developed by this study is a reliable and valid instrument and can be used to assess needs of pregnancy and postpartum adaptation and can be utilized in providing nursing interventions for immigrant women.

• YAKHAK HOEJI
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• v.39 no.6
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• pp.585-592
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• 1995

Soil microorganisms producing immunomoduators that can restore ultraviolet B (UVB) radiation-induced suppression of the immune response were screened in vitro. Exposure of freshly isolated murine epidermal cells (EC) to $180{\;}J/m^{2}$ of UVB radiation resulted in approximately 90% impairtnent of accessory cell function, as measured by their ability to support anti-CD3 monoclonal antibody-induced T-cell mitogenesis. When the culture supenmtants of 150 actinomycete strains were exanuned for their capacity to prevent or repair the UVB-induced impairment of accessory cell function, 4 of them were identified to contain immunomodulators that can restore the decreased accessory cell finiction. The soil isolate that showed the most effective restorative activity, G40025. was selected and fturther characters Addition of 10.mu.l of the culture supernatant of G40025 grown in G-media to cultures of UVB-irradiated EC right after UVB-irradiation restored the decreased accessory cell function by 58%. The immunomodtdator produced by G40025 appeared to be stable at 100.deg. C for 10 min. Taxonomical studies by cultural, morphological, and physiological characterization showed that the soil isolate, G40025, belongs to the genus Streptomyces.

• Journal of The Korean Association of Information Education
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• v.14 no.1
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• pp.13-23
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• 2010

In recent creativity becomes a new request in the knowledge and information age. Robot programming education is an effective teaching method for improvement of creativity. Existing robot programming tools includes text-based or GUI-based development environment. Most of programming tools provide a simple tutorial system without interactive activity for beginners. In this paper, we propose an online robot programming education system based on web2.0, which embedded collaborative code creating tool, interactive tutorial chat and video conference tool to support collaborative code creating via web 2.0. Knowledge sharing tool allows users to share their collaborative source code. Besides, it makes users gained the experience and knowledge of program designing efficiently.

• Journal of Korean Academy of Nursing Administration
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• v.17 no.3
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• pp.315-326
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• 2011

Purpose: Purposes of this study were to identify non-value-added nursing activities (NVANAs) and to estimate the amount of time spent on NVANAs among total nursing activities. Methods: Non-value-added nursing activities were identified though the use of a focus group. The nurses in the focus group were nurses working in a tertiary hospital. They discussed possible activities that could be NVANAs. Based on the focus group discussion, a pilot study was done to examine the actual occurrence of NVANAs in clinical settings. Results: The focus group discussion showed that NVANAs occurred in ten categories of nursing performances including communication with physicians, communication with other departments, medications, equipment/supplies, nursing records, tests, admission, discharge, and transfer. Direct nursing activities accounted for 35.5% of total nursing activities while indirect nursing activities accounted for 64.5%. Of indirect nursing activities, 16% were NVANAs. Most NVANAs were related to communication and equipment/supplies. Conclusions: To improve the quality and efficiency of nursing activities, it is necessary to identify NVANAs and their causes. Results of this study suggest that improvement in the work process and nursing unit structure, support for equipment/supplies, and effective communication are needed to reduce NVANAs in tertiary hospitals in Korea.

• Journal of Korean Academy of Nursing
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• v.13 no.3
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• pp.119-126
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• 1983

Early extra-uterine development of the newborn infant has the potential for clarifying important questions of nature and care taking environment. In this study, tactile and auditory stimulation is used on .a group of infants to determine the effects of their response. Infants were tested by EKG at 24∼48 hrs after birth ana all they are free from complication. Stimuli presented were-touch and sound (40dB, 70dB and 40∼70dB). The result of the study were as follows: 1) The heart rate was seen to depend on their sleep-wake state. (light sleep ; 125/min, eyes: open & motor activity increase ； 151/min crying ; 185/min). 2) The heart rate affected by tactile & auditory stimulus. The heart rate response was acceleration above the prestimulus level. (tactile, 231min increase, auditory ; 16∼21/min increase), and heart rate change was seen to depend on prestimulus rate. (γ=.73) 3) There was a decrease in heart rate when they were soothe. (touch ; 24.8sec, 21/min decrease, pacifier ; 14.5sec, 26/min decrease) and significant difference in time between touch and pacifier (t= 1.76, p<0.05). This result support the evaluation of newborn infant's sensory abilitics, and has even begin to influence changes in nursing care. But systemic monitoring of newborn infants response would. further define.

• PNF and Movement
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• v.7 no.1
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• pp.33-46
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• 2009

Purpose : N.A.P.(Neuromuscular Skeletal Plasticity) an integrative neuro-orthopedic concept to facilitate motor strategies in daily life. The primary thesis is, that treatment of body functions and structural impairments should be integrated within goal-oriented activities. The purpose of this article is to demonstrate that the functional activity itself, determines the structure. Material and Methods : A case report of a dentist with brachial plexus lesion after a motor vehicle accident is presented. The necessity for training body functions within relevant tasks is undermined by references which emphasize the importance of training realistic activities to enhance long-term changes in neural representation. Results : The treatment methods presented in this case show significant effects for the patient's ability to participate in his profession within less than a year's time after his motor vehicle accident. Conclusions : Current evidence supports the treatment methods of this concept. The inability to flex his elbow and supinate his forearm placed a considerable doubt to his ability to ever be able to participate in his profession again. Structural reorganization is possible and depends on functional demands, which need to be trained task-specifically. Single case reports may serve as the basis for further randomized controlled studies to support the efficacy of the treatment methods within the N.A.P. concept.

• Speech Sciences
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• v.8 no.3
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• pp.15-30
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• 2001

Lateralization, the change of a coronal nasal into a lateral in an l-n sequence, has been considered to be prosodically unrestricted, e.g. an utterance-span rule, in Korean (Han 1993, Park 1990). However, aerodynamic data of the nasal do not corroborate their claims. In the paper, I look at how lateralization can best be characterized. Specifically, I ask whether its domain is best treated via a syntax-based (Nespor & Vogel 1986, Selkirk 1984) or an intonation-based approach (Pierrehumbert 1980, Jun 1993) to prosodic structure. Based on nasal airflow data as a means of monitoring velum activity coincident with a nasal stop in an l-n sequence, combined with pitch tracks to define an accentual phrase, I argue that lateralization is neither an utterance-span rule nor a syntax-based rule. Sentences recorded with a potential environment for lateralization show that lateralization occurs within an accentural phrase but is blocked between accentual phrase boundaries. When intonation-based and syntax-based models disagree about phrase boundaries, lateralization only occurs where the intonation-based model predicts it will. This indicates that lateralization is best defined as an accentual pheonomenon, being sensitive to the accentual phrase. This finding lends further support to an intonation-based model for Korean prosodic structure (Jun 1993).