• Title/Summary/Keyword: Activity Support

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Synthesis of 7$\alpha$-Hydroxycephalosporin C by Immobilized Enzyme (고정화 효소를 이용한 7$\alpha$-hydroxycephalosporin C의 합성)

  • 김정근;강희일;박영훈;최용진;이종욱
    • Korean Journal of Microbiology
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    • v.37 no.2
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    • pp.164-169
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    • 2001
  • The conversion of cephalosporin C to 7$\alpha$-hydroxycephalosporin C was examined with the cell-free extract of several cephamycin producing strains. Streptomyces clavuligerus ATCC 27064 was the most potent strain for the activity of cephalosporin 7$\alpha$-hydroxylase. Partially purified and immobilized cephalosporin 7$\alpha$-hydroxylase with resins were used to synthesize 7$\alpha$-hydroxycephalosporin C from the substrate, cephalosporin C. The molecular weight of the product isolated from the reaction mixture were determined to be 431 by ESI-Mass. $^1H$ NMR also support the conversion of cephalosporin C to 7$\alpha$-hydroxycephalosporin C by immobilized enzyme.

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Design of Nanocluster Based Material with Catalytic Properties

  • Tadachika Nakayama;Kim, Chang-Yeoul;Tohru Sekino;Choa, Yong-Ho;Takafumi Kusunose;Yamato Hayashi;Koichi Niibara
    • Journal of Powder Materials
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    • v.8 no.3
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    • pp.197-200
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    • 2001
  • Modified inert gas condensation method was used to produce the nanocluster composites of $CuO/CeO_2$. High-resolution TEM, SEM and catalytic measurements have been used to characterize the samples and study the synergistic effect between the CuO phase and $CeO_2$(ceria) support. By varying the He pressure, the heating temperature and configuration of the heating boats inside the modified gas condensation chamber, nanoclusters of varying sizes, shapes and composition can be produced. The composition and nanostructured morphology were shown to influence the catalytic properties of the system. A copper content around 10 at% with a morphology that favors high-energy surfaces of ceria is shown to be beneficial for a high catalytic activity.

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Comparative Study on the Fine Structure of Small Cells in the Space of Disse of Various Animal Livers (각종 동물 간소엽내 Disse강의 소세포에 관한 미세구조적 비교 연구)

  • Hwang, Seung-Jun;Shin, Young-Chul
    • Applied Microscopy
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    • v.22 no.1
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    • pp.15-32
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    • 1992
  • This study was an attempt to investigate and compare the fine structure of small cells in the space of Disse of various animal livers. All animal livers contained small cells with or without lipid droplets and the one with lipid droplet seemed to be more developed and show an abundance of activity in function. The fine structure of the small cells observed in the nonmammals was similar to that of Ito cell in the mammal. The electron density of the small cells was similar to that of other cell types in the same animal liver. The cisternal dilation of rough endoplasmic reticulum and Golgi apparatus was more predominant in the mammalian Ito cells. In the nonmammalian, aquatic vertebrates, however, lysosomes and filaments are much more abundant in the Ito cell and its abundant cytoplasmic processes rich in filaments were usually extended between the parenchymal cells. The disparity in size of organelles and numbers of lipid droplets in the small cells showed a tendency similar to those of other cell types in the same animal. From these results, it is considered that the small cells in the space of Disse is a Ito cell and the Ito cell without lipid droplets differentiates into the one containing lipid droplets according to the characteristics of the different animals respectively, and that the Ito cells in the mammals are more active in metabolic function, while those in the nonmammalian aquatic vertebrates are abundant in support of parenchyme.

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Improving Performance of Remote TCP in Cognitive Radio Networks

  • Yang, Hyun;Cho, Sungrae;Park, Chang Yun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.6 no.9
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    • pp.2323-2340
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    • 2012
  • Recent advances in cognitive radio technology have drawn immense attention to higher layer protocols above medium access control, such as transmission control protocol (TCP). Most proposals to improve the TCP performance in cognitive radio (CR) networks have assumed that either all nodes are in CR networks or the TCP sender side is in CR links. In those proposals, lower layer information such as the CR link status could be easily exploited to adjust the congestion window and improve throughput. In this paper, we consider a TCP network in which the TCP sender is located remotely over the Internet while the TCP receiver is connected by a CR link. This topology is more realistic than the earlier proposals, but the lower layer information cannot be exploited. Under this assumption, we propose an enhanced TCP protocol for CR networks called TCP for cognitive radio (TCP-CR) to improve the existing TCP by (1) detection of primary user (PU) interference by a remote sender without support from lower layers, (2) delayed congestion control (DCC) based on PU detection when the retransmission timeout (RTO) expires, and (3) exploitation of two separate scales of the congestion window adapted for PU activity. Performance evaluation demonstrated that the proposed TCP-CR achieves up to 255% improvement of the end-to-end throughput. Furthermore, we verified that the proposed TCP does not deteriorate the fairness of existing TCP flows and does not cause congestions.

Knowledge, Satisfaction, and Education Needs in Sexual Rehabilitation of Male Patients with Spinal Cord-Injury (척수장애 남자 환자의 성재활 지식, 성생활 만족 및 성재활 교육 요구)

  • Kim, Sun-Joung;Lim, Ji-Young;Cho, In-Sook;Ham, Ok-Kyung
    • Journal of Home Health Care Nursing
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    • v.15 no.2
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    • pp.91-98
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    • 2008
  • Purpose: We measured the knowledge, satisfaction, and education needs in sexual rehabilitation of male patients diagnosed with a spinal cord injury. Methods: We recruited 104 patients from a general rehabilitation hospital. Data were collected between April 4 and May 9, 2008. Knowledge of sexual rehabilitation, satisfaction, and educational needs were measured using self-report questionnaires. Results: Points for knowledge of sexual rehabilitation were 6.75 out of 20, sexual satisfaction was 3.02 out of 5, and demand for sexual rehabilitation education were 3.54 out of 5. Most (93.27%) of the patients wanted to have a sex life, and many (75%)were willing to participate in sexual rehabilitation education. There were no differences in knowledge or satisfaction based on general characteristics. However, sexual satisfaction of the university graduates was higher than the lower education group. Conclusion: Male patients with spinal cord disorders are interested in a sex life and demand sexual rehabilitation education. These findings should support the development of sexual rehabilitation programs.

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Current Status and Prospects of Quality Evaluation in Sesame (참깨의 품질평가 현황과 전망)

  • 류수노;김관수;이은정
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.47
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    • pp.140-149
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    • 2002
  • Sesame (Sesamum indicum L.) is probably the most ancient oilseed crop known in the world. Sesame seed is known for its high nutritional value and for having oil (51%) and protein (20%) content. The fatty acid composition of sesame oil is palmitic acid (7.8%), stearic acid (3.6%), oleic acid (45.3%), and linoleic acid (37.7%). Sesame oil is characterized by a very high oxidative stability compared with other vegetable oils. Two lignan-type compounds, sesamin and sesamolin, are the major constituents of sesame oil unsaponifiables. Sesamol (a sesamolin derivative) can be present in sesame seeds and oils in very small amount. Other lignans and sesamol are also present in sesame seeds and oils in very small amount as aglycones. Lipid oxidation activity was significantly lower in the sesamolin-fed rats, which suggests that sesamolin and its metabolites contribute to the antioxidative properties of sesame seeds and oil and support that sesame lignans reduce susceptibility to oxidative stress. Sesaminols strongly inhibit lipid peroxidation related to their ability to scavenge free radical. The sesame seed lignan act synergistically with vitamin I in rats fed a low $\alpha$-tocopherol diet and cause a marked increase in a u-tocopherol concentration in the blood and tissue of rats fed an $\alpha$-tocopherol containing diet with sesame seed or its lignan. The authors are reviewed and discussed for present status and prospects of quality evaluation and researched in sesame seeds to provide and refers the condensed informations on their quality.

An Approach to Composite Techniques and Application of EJB Component using Adapter Pattern (Adapter패턴을 이용한 EJB 컴포넌트 조립 기법 및 응용)

  • Jeong Hwa-Young
    • Journal of Internet Computing and Services
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    • v.4 no.1
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    • pp.67-74
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    • 2003
  • According to change of software development technique as design pattern, component based development etc.., web server development part is applied activity to fit in various user requirement. Especially, EJB as sewer side component model much researches and introduce by easy and various development support. Also, component composing techniques is receiving many interests by easy and efficient application way that architecture based C2 style architecture with message handling. But, in case of EJB component that can not cail thread, C2 framework modification is unavoidable for component composition by C2 style architeccture. For this, we propose techniques to use Adapter pattern to be one of structure pattern among pattern. That is, did so that component composition by C2 style architecture may can consist changing to be able to call thread function in EJB by Adapter pattern.

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A thought on Korea food culture and collectivity+ (한국인의 공동체의식과 식문화에 대한 소고(小考)+)

  • Oh, Se-Young;Lee, Hun
    • Journal of the Korean Society of Food Culture
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    • v.19 no.5
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    • pp.556-565
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    • 2004
  • This study examined dietary culture in Korea regarding collectivism through literature review. Based on the evidence from the origin of lineage and traditional customs, the Koreans' traditional collectivity appeared to have been grounded upon the northen nomadic culture emphasizing sentimental collectivity and harmonized with the characteristics of southern agrarian society related to mutual support and sociability. The inseparable relationship between collectivity and food was well revealed in the occasions such as rice-planting, kimchi and jang makings in which pooled labor was common as well as the gathering of mutual aid association. In these occasions, foods were offered and shared among members. Food sharing was a main activity and almost play a central role regarding the promotion of friendly relations among each other. In sacrificial memorials, food sharing was extended not only to the live persons but also to the passing spirits. Collectivity was also disclosed in the eating or table manners of Koreans. Koreans quite literally share food at every meal since the side dishes placed centrally on the table. The taste of Korean foods is completed inside the mouth by mixing foods with various combination, which let people create their own choice of taste. Therefore, the collectivity manners at the table appeared to be harmonized with individual freedom of creating his/her own taste of foods. The collectivity is still a very important concept in modem Korean dietary culture, as reflected by an increase of restaurants sewed shared dishes.

Apolar growth of Neurospora crassa leads to increased secretion of extracellular proteins

  • Lee, In-Hyung;Rodney G. Walline;Michael Plamann
    • Proceedings of the Korean Society for Applied Microbiology Conference
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    • 2000.04a
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    • pp.78-89
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    • 2000
  • Protein secretion in filamentous fungi has been shown to be restricted to actively growing hyphal tips. To determine whether an increase in the amount of growing surface area of a fungus can lead to an increase in the amount of protein secretion, we examined secretion in a temperature-sensitive Neurospora crassa mcb mutant that shows a loss of growth polarity when incubated at restrictive-temperature. Incubation of the mcb mutant at restrictive-temperature results in a three- to five-fold increase in the level of extracellular protein and a 20- fold increase in carboxymethyl cellulase activity relative to a wild-type strain. A mutation in the cr-l gene has been shown previously to suppress the apolar growth phenotype of the mcb mutant, and we find that the level of extracellular protein produced by a mcb; cr-l double mutant was reduced to that of the wild-type control. Immunolocalization of a secreted endoglucanase revealed that proteins are secreted mainly at hyphal tips in hyphae exhibiting polar growth and over the entire surface area of bulbous regions of hyphae that are produced following a shift of the mcb mutant to restrictive-temperature. These results support the hypothesis that secretion of extracellular protein by a filamentous fungus can be significantly increased by mutations that alter growth polarity.

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A Study on the Development of the School Readiness Inventory for Preschoolers (취학 전 유아의 학교준비도 검사 개발 연구)

  • Bang, So Young;Hwang, Hye Jung
    • Human Ecology Research
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    • v.53 no.1
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    • pp.29-47
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    • 2015
  • The purpose of this study is to conceptualize the definition of school readiness specific to the context of the Republic of Korea. The school readiness test can be used as basic data to enable early childhood educational institutes to determine the general readiness of preschoolers and provide support to fit individual characteristics. For this purpose, six stages of the school readiness development process were considered, that is, draft development, primary preliminary survey, primary expert verification, secondary expert verification, secondary preliminary survey, and main survey. In the main survey, tests were conducted using the school readiness final draft targeting 344 preschoolers living in Seoul and Gyeonggi-do. The item discrimination power analysis and factor analysis for the examination area and question area were also conducted. Consequently, a test tool was developed on the basic of the results obtained, consisting of 129 items in the five areas of knowledge, function, adaptation, tendency, and attitude. The knowledge area was divided into general, linguistic, and mathematical knowledge, and the function area into fine motor function, basic living ability, expressive function, and gross motor function. The adaptation area was classified into adaptation activity, separation anxiety, maladaptive behavior, and environment adaptation; the tendency area into learning tendency; others understanding, and individual tendency, and the attitude area into rule compliance and life habits.