• Title/Summary/Keyword: Activity Pattern

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Induction of Oscillatory Firing Activity by TTX in Rat Cerebellar Purkinje Cells

  • Seo, Wha-Sook
    • The Korean Journal of Physiology
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    • v.29 no.1
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    • pp.103-111
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    • 1995
  • Intracellular recordings were obtained from Purkinje cells in rat cerebellar slices maintained in vitro. Adding tetrodotoxin to the superfusion solution produced a typical pattern of repetitive burst firing consisting of a cluster of action potentials followed by a long hyperpolarization. TTX-induced oscillatory activity was not due to modulation of membrane potential although underlying mechanisms for maintenance of oscillatory activity were influenced by membrane voltage. The mechanism of TTX-induced oscillation was not related to the presence or amplitude of $I_h$ and could still induce the oscillatory activity after blockade of $I_h$ by cesium. The result from an experiment in which QX-314 was injected intracellularly strongly suggested that TTX-induced oscillatory firing activity was due to blockade of post-synaptic $Na^{+}$ currents intrinsic to PCs.

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LACTIC ACID DEHYDROGENASE ISOENZYME IN THE PERIODIC AMPUTATED RAT INCISOR PULP (백서 전치 주기적절제시 치수내 LDH ISOENZYME에 관한 연구)

  • Choi, Kuen-Bae
    • The Journal of the Korean dental association
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    • v.10 no.1
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    • pp.15-21
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    • 1972
  • In the periodic amputated rat incisor pulp, the distribution of five isoenzymes of lactic acid dehydrogenase was evaluated and the total LDH activity was assayed. This study hs established the followings; 1) It demonstrates the existence of five distinct isoenzymes of LDH, with LDH-1 and LDH-2 predominating, in the rat incisor pulp. 2) The total LDH activity in periodically amputated rat incisor pulp is markedly increased as compared to the normal rat incisor pulp. 3) It is possible that the periodic amputation of tooth effects the pattern of LDH isoenzymes in the pulp, especially LDH-1 and LDH-2 region.

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A Study on the Pattern Recognition Rate of Partial Discharge in GIS using an Artificial Neural Network

  • Kang Yoon-Sik;Lee Chang-Joon;Kang Won-Jong;Lee Hee-Cheol;Park Jong-Wha
    • KIEE International Transactions on Electrophysics and Applications
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    • v.5C no.2
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    • pp.63-66
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    • 2005
  • This paper describes analysis and pattern recognition techniques for Partial Discharge(PD) signals in Gas Insulated Switchgears (GIS). Detection of PD signals is one of the most important factors in the predictive maintenance of GIS. One of the methods of detection is electro magnetic wave detection within the Ultra High Frequency (UHF) band (300MHz $\~$ 3GHz). In this paper, PD activity simulation is generated using three types of artificial defects, which were detected by a UHF PD sensor installed in the GIS. The detected PD signals were performed on three-dimensional phi-q-n analysis. Finally, parameters were calculated and an Artificial Neural Network (ANN) was applied for PD pattern recognition. As a result, it was possible to discriminate and classify the defects.

Comparison of Physical Activity Level, Physical Activity Pattern and Energy Expenditure in Male and Female Elementary School Soccer Players using Accelerometer and Physical Activity Diary (가속도계와 신체활동일기를 이용한 초등학생 축구선수 남녀의 신체활동수준, 신체활동 패턴 및 에너지소비량 비교)

  • An, Hae-Sun;Choi, Su-Ji;Lee, Mo-Ran;Lee, Jung-Sook;Kim, Eun-Kyung
    • Korean Journal of Community Nutrition
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    • v.22 no.6
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    • pp.529-542
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    • 2017
  • Objectives: The purpose of this study was to compare the physical activity level (PAL), the physical activity pattern and the energy expenditure in male and female elementary school soccer players using the accelerometer and the physical activity diary. Methods: Twenty-five (male 11, female 14) elementary school soccer players (9-12 years) participated in this study. During their daily activities, they wore an accelerometer for seven days (five weekdays and two weekend days) and completed the physical activity diary for three days (two weekdays and one weekend day). PAL was calculated by using the physical activity diary and three equations (Pate Preschool, Freedson Children, and Freedson) were used to calculate the intensity of physical activity and energy expenditure from the counts of accelerometer. Results: The average of physical activity by day of the week, CPM (Counts Per Minute) and METs (Metabolic Equivalents) were significantly higher in males ($723.3{\pm}149.2CPM$, $2.07{\pm}0.18METs$) compared to females ($505.6{\pm}119.9CPM$, $1.79{\pm}0.20METs$), but there was no significant difference in PAEE (Physical Activity Energy Expenditure) between the two groups (males: $15.5{\pm}9.1kcal/day$, females: $11.5{\pm}6.0kcal/day$). During weekdays, physical activity intensity was significantly higher in males compared to females at lunch time and training time than at other times. In both genders, the PAL was higher during weekdays (males 1.98, females 1.89) compared to weekend (males 1.62, females 1.61) (p<0.05). Conclusions: Our study observations suggest the necessity to develop an accelerometer equation for accurately evaluating the physical activity of elementary school athletes.

An Active Mining Framework Design using Spatial-Temporal Ontology (시공간 온톨로지를 이용한 능동 마이닝 프레임워크 설계)

  • Hwang, Jeong-Hee;Noh, Si-Choon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.9
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    • pp.3524-3531
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    • 2010
  • In order to supply suitable services to users in ubiquitous computing environments, it is important to consider both location and time information which is related to all object and user's activity. To do this, in this paper, we design a spatial-temporal ontology considering user context and propose a system architecture for active mining user activity and service pattern. The proposed system is a framework for active mining user activity and service pattern by considering the relation between user context and object based on trigger system.

Growth-Dependent Variations in Antioxidant and Redox Enzyme Activities of Schizosaccharomyces pombe

  • Cho, Young-Wook;Park, Eun-Hee;Ahn, Ki-Sup;Kim, Dae-Myung;Lim, Chang-Jin
    • BMB Reports
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    • v.34 no.3
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    • pp.278-283
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    • 2001
  • Antioxidant and redox enzyme activities are known to be involved in the cellular responses to various stresses. Their variations were observed according to the growth cycle of the fission yeast Schizosaccharomyces pombe. Peroxidase activity appeared to be notably higher in the early exponential phase than in the mid-exponential and stationary phases. However, catalase activity showed a variation pattern resembling the growth curve. Glutathione S-transferase activity was higher in the early exponential and late stationary phases. Activities of the two redox enzymes, thioredoxin and thioltransferase (glutaredoxin), were high in the stationary phase. However, their activities appeared to increase from the early exponential to mid-exponential phase. Total glutathione content had a varying pattern similar to that of thioredoxin and thioltransferase. However, its content in the early exponential phase was high. These results propose that antioxidant and redox enzymes tested are also involved in the mechanism of cell growth.

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$^{67}Gallium$ Scan Findings in Miliary Tuberculosis (속립성 결핵의 $^{67}Gallium$ Scan 소견)

  • Lee, Myeong-Seob;Kim, Eung-Jo;Hong, In-Soo;Sung, Ki-Jun;Park, Hyun-Ju
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.1
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    • pp.111-115
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    • 1992
  • Miliary Tuberculosis is an illness produced by acute dissemination of tubercle bacilli via the blood stream. In chest roentgenogram, a diffuse "miliary" infiltrates are usually seen, but normal or suspicious ground glass pattern also can be seen in early manifestation. Ten patients of miliary tuberculosis who underwent whole-body $^{67}Ga-citrate$ scintigraphy were evaluated retrospectively to study usefulness of Ga-scan for early diagnosis of miliary Tbc and evaluation of disease activity. All of ten patients demonstrated significantly diffuse bilateral pulmonary uptakes on 48 hours image. All of three patients of ground-glass pattern in chest roentgemogram also demonstrated increased uptakes. In the statistical analysis, the severity of chest roentgenographic findings showed positive correlation with the activity on Ga?scan. These results suggest that Gallium scan is useful for diagnosis of early miliary tuberculosis and for evaluation of disease activity on follow-up examination of miliary tuberculosis of lung.

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Development of a Modular-type Knee-assistive Wearable System (무릎근력 지원용 모듈식 웨어러블 시스템 개발)

  • Yu, Seung-Nam;Han, Jung-Soo;Han, Chang-Soo
    • Journal of the Ergonomics Society of Korea
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    • v.29 no.3
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    • pp.357-364
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    • 2010
  • This study proposes a lower-limb exoskeleton system that is controlled by a wearer's muscle activity. This system is designed by following procedure. First, analyze the muscle activation patterns of human leg while walking. Second, select the adequate actuator to support the human walking based on calculation of required force of knee joint for step walking. Third, unit type knee and ankle orthotics are integrated with selected actuator. Finally, using this knee-assistive system (KAS) and developed muscle stiffness sensors (MSS), the muscle activity pattern of the subject is analyzed while he is walking on the stair. This study proposes an operating algorithm of KAS based on command signal of MSS which is generated by motion intent of human. A healthy and normal subject walked while wearing the developed powered-knee exoskeleton on his/her knees, and measured effectively assisted plantar flexor strength of the subject's knees and those neighboring muscles. Finally, capabilities and feasibility of the KAS are evaluated by testing the adapted motor pattern and the EMG signal variance while walking with exoskeleton. These results shows that developed exoskeleton which controlled by muscle activity could help human's walking acceptably.

Changes of Peroxidsse Isozyme Pattern and Formation of Cell Wall of Hairy Root Irlduced by Agrohacterium rhisogenes from Potato Tuber (감자(Solanum tuberosum. L) 괴경에 있어서 Agrobacterium rhizogenes에 의해 형질전환된 조직세포의 세포벽 형성과 peroxidase isozyme 양상의 변화)

  • 정현숙;김영희
    • KSBB Journal
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    • v.6 no.1
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    • pp.27-33
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    • 1991
  • Hairy root induced by A. rhizogenes from potato tuber (Solanm tuberosum L.) synthesized the agropine and mannopine which were demonstrated with paper electrophoresis. And the starch contents in hairy root were increased gradually following the developmental stage. But protein contents were decreased. The activity of ${\beta}-glucan$ synthetase II(GSII) which is related to the cell wall biosynthesis was stimulated in hairy root on the developmental stage. And chloropromazine did not influence the activity of GS II while verapamil inhibited about 60% of the activity GS II. Therefore, these results showed $Ca^{2+}$ to be effective factor in the cell wall formation. Isozyme pattern of peroxidase was investigated in the callus and hairy root induced from potato tuber.

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Monitoring of FCW/DCW ratio, Production of Protein and Peroxidase Activity During Suspension Culture of Taxus chinesis (주목 세포 현탁배양 중, FCW/DCW ratio, 단백질 생산 및 peroxidase활성 조사)

  • 최형균;윤정환;김상익;송재영;김진현;최호준;홍승서
    • KSBB Journal
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    • v.15 no.5
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    • pp.525-528
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    • 2000
  • Time course monitoring of FCW/DCW ratio, production of intra and extracellular protein, and peroxidase activity were performed during suspension culture of Taxus chinensis cells. The observed FCW/DCW ratio was 12 at day 14, which was the lowest value during cultivation, and the specific protein production, based on dry cell weight, was also the lowest at day 14, which showed 4.3 mg/g DCW. The pattern of POD activity was similar to that of protein production. The results in this report were obtained using actively growing cells in flasks, therefore it is possible to use those results to control the process and indicate the stresses imposed on cells during large-scale cultivation.

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