• 한국건설관리학회논문집
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• 제6권4호
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• pp.80-90
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• 2005

프로젝트의 일정 네트워크는 선-후행 관계로 정의된 액티 비 티들로 구성되어 있다 액티비티를 완료하는데 소요되는 기간은 다양한 단축-지연 원인들에 의해 임의적이고, 확률-통계적 인 특성을 지닌다. 이러한 특성은 최종공사기간을 불확실하게하며, 재무리스크의 주요인이 된다. 본 연구는 선행 연구에서 개발된 확률-통계적 일정 시뮬레이션 시스템(Stochastic Project Scheduling Simulation)을 확장하여 액티비티 기간이 임의적으로 변동함에 따라 최종공사비가 어떻게 거동하는지 추정하는 방법론을 제시한다. 액티비티 기간을 임의의 변수로 취급하였고, 액티비티에 할당된 직접공사비에 공사기간의 단축-지연에 따른 간접비의 증감을 반영하여 최종공사비를 추정하였다. 액티비티 기간의 변동에 따라 의존 변수인 간접비가 변동하는 특성을 고려하여 시뮬레이션 출력값들(최종공사기간들)의 통계적 특성을 정량적으로 분석하여 최종공사비를 추정하였으며, 예비할 필요가 있는 지체보상금의 정도를 정량화하였다. 기존의 결정론적 기법이 불확실성을 내재한 체 지체 보상금의 비율을 주관적으로 적용해 왔던 반면, 본 연구에서 제시된 기법은 확실성과 신뢰도를 가지고 지체보상금의 비율을 책정할 수 있도록 하는 방법론을 제시하고 있다. 하나의 예제 프로젝트가 시뮬레이션을 이용한 정량분석기법을 예시하기위해 사용되었으며, 불확실성을 내포하고 있는 액티비티 기간들이 최종공사비에 미치는 영향을 검증하기위해 시뮬레이션 모의실험을 실행하였다 자동화된 민감도분석 기법을 이용하여 액티비티 기간을 정의하는 확률분포함수의 통계적 위치를 변화시킴에 따라 최종공사기간 및 최종공사비가 어떠한 거동을 나타내는지 확인하였다. 예제로 사용된 표본 프로젝트에 내재되어있는 재무리스크에 대응하기위해 지체보상금을 어느 정도까지 보유할 필요가 있는지를 정량적으로 분석하고, 의사결정을 위해 어떻게 적용될 수 있는지를 소개한다. 본 연구에 제시된 기법은 연구자들 및 현업 종사자들에게 최종공사비 예측에있어서 액티비티 기간 변화의 확률적 영향과 이론적 의미를 밝힘으로 프로젝트 자본계획과 관련된 위기관리에 진보된 예측방법론을 제공한다.

• Geomechanics and Engineering
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• 제17권5호
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• pp.421-427
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• 2019

Coastal erosion is becoming a significant problem in Greece, Bangladesh, and globally. For the prevention and minimization of damage from coastal erosion, combinations of various structures have been used conventionally. However, most of these methods are expensive. Therefore, creating artificial beachrock using local ureolytic bacteria and the MICP (Microbially Induced Carbonate Precipitation) method can be an alternative for coastal erosion protection, as it is a sustainable and eco-friendly biological ground improvement technique. Most research on MICP has been confined to land ureolytic bacteria and limited attention has been paid to coastal ureolytic bacteria for the measurement of urease activity. Subsequently, their various environmental effects have not been investigated. Therefore, for the successful application of MICP to coastal erosion protection, the type of bacteria, bacterial cell concentration, reaction temperature, cell culture duration, carbonate precipitation trend, pH of the media that controls the activity of the urease enzyme, etc., are evaluated. In this study, the effects of temperature, pH, and culture duration, as well as the trend in carbonate precipitation of coastal ureolytic bacteria isolated from two coastal regions in Greece and Bangladesh, were evaluated. The results showed that urease activity of coastal ureolytic bacteria species relies on some environmental parameters that are very important for successful sand solidification. In future, we aim to apply these findings towards the creation of artificial beachrock in combination with a geotextile tube for coastal erosion protection in Mediterranean countries, Bangladesh, and globally, for bio-mediated soil improvement.

• 대한교통학회:학술대회논문집
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• 대한교통학회 1994년도 제26회 학술발표
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• pp.26-60
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• 1994

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제20권3호
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• pp.146-151
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• 2009

Objectives : We conducted this study to investigate the relationship between sleep duration and body mass index (BMI), in Korean children. Methods : We performed a cross-sectional analysis of data collected on 3,639 boys and girls (aged 7-12) in Daegu, Korea. The data included each child's age, sex, weight, height, extracurricular activities, bedtime, wake-up time, sleep latency, total sleep duration, parents' occupations, and parents' educational levels. The relationship between sleep duration and each variable was examined via analysis of variance (ANOVA). Results : The analysis showed an association between short sleep duration and high BMI. Boys showed a graded inverse relationship between sleep duration and BMI. However, there was no significant corresponding result for girls. In the total sample, hours of computer use, time when the computer was turned off, time when the television was turned off, mother's bedtime, and hours of extracurricular activity were associated with longer sleep duration. No association was found between sleep duration and hours of watching television, child's wake-up time, or educational level of the parents. Conclusion : The results of this study show an inverse relationship between a child's sleep duration and BMI；thus, children with shorter sleep duration tend to have higher BMIs.

• 대한한의학회지
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• 제27권3호
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• pp.63-76
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• 2006

Objective: These studies were undertaken to evaluate the effects of the different administration duration of Morindae Radix extract solution on spermatogenic abilities such as concentration, motility and morphological normality of sperm from the testes and the activities of sperm hyaluronidase. Materials and Method: We used 8-week-old ICR mice and administered 0.3mg/g extract solution of Morindae Radix once a day for 30, 60, 90 and 120 days. The control group was administered normal saline in the same way and duration. We examined the number of total, motile and normal sperm from the cauda epididymis. We also compared the testicular tissue, especially seminiferous tubules, between the control and treated groups by histochemical methods. Finally, we observed the difference of sperm hyaluronidase activities between the control and treated groups. Results: Significant administration duration-dependent differences were observed in the concentration of total sperm, motility and normality of spermatozoa of the Morindae Radix extract solution administered groups compared to the control group. In the histological analysis of the testicular tissues, the enlargement of testicular lobe diameter and apparent vasculogenesis between testicular lobes were observed in the Morindae Radix extract solution administered groups compared to the control group. Also, the activity of hyaluronidase was significantly increased in the Morindae Radix extract solution administered groups compared to the control group. Conclusions: This study shows that the beneficial effect of Morindae Radix extract solution on the concentration, motility and morphology of sperm, the testicular tissues and the activities of sperm hyaluronidase increased the greater the duration the mice were administered it. We suggest that Morindae Radix may be useful for the treatment of male sexual dysfunction and infertility.

• 대한한방부인과학회지
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• 제24권1호
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• pp.42-62
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• 2011

Objective: This study was performed to investigate the effect of acupuncture at HT8 on brain activity in perimenopausal women using fMRI. Methods: 15 healthy perimenopausal women volunteered in the study. No stimulation, sham stimulation, duration of acupuncture treatment on HT8, and rotation of acupuncture treatment on HT8 were randomly given for 6 minutes, with 20 seconds' intervals. Results: 1. In comparison with sham stimulation(Sham-B) and duration of acupucture (S1-B, S1-Sham, S2-S1), the areas of fMRI signal activation areas were just like cases including no stimulation. But the areas of vision were activated in S1-Sham. 2. In comparison with duration of acupuncture(S1-B, S1-Sham, S2-S1) and rotation of acupuncture(S2-B, S2-Sham, S2-S1), the areas of vision were activated in duration of acupuncture, and Supplementary motor area(SMA) were especially activated in rotation of acupuncture. Conclusions: After using fMRI and analysing effect of acupuncture treatment at HT8, we could confirm that fMRI signal activation areas by acupuncture treatment at HT8 were different from areas by sham stimulation. And according to acupuncture stimulation methods with duration and rotation, etc, we could confirm the specific reactions of series, and could get useful basic data for research of acupuncture from now on.

• 생약학회지
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• 제8권3호
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• pp.115-119
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• 1977

Black pepper (Piper nigrum L.) among several irritating spices tested was highly effective on the duration of hexobarbital hypnosis in mice. Pretreatment of mice with the methanolic extract of black pepper (60mg/kg i.p.) prolonged markedly the duration of hexobarbital sleeping time. Three consecutive daily administrations of the same dose of black pepper extract, however, shortened (37%) the duration of hexobarbital sleeping time. The ether soluble fraction of black pepper extract caused most potent effects on the duration of hexobarbital hypnosis. From the above results, it was postulated that the lipid soluble components of black pepper might considerably change the drug action and metabolism by altering drug metabolizing enzyme systems.

• Biomolecules & Therapeutics
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• 제27권5호
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• pp.435-441
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• 2019

The capsaicin receptor TRPV1 (transient receptor potential vanilloid 1) has been an object of intense interest for pharmacological development on account of its critical role in nociception. In the course of structure activity analysis, it has become apparent that TRPV1 ligands may vary dramatically in the rates at which they interact with TRPV1, presumably reflecting differences in their abilities to penetrate into the cell. Using a fast penetrating agonist together with an excess of a slower penetrating antagonist, we find that we can induce an agonist response of limited duration and, moreover, the duration of the agonist response remains largely independent of the absolute dose of agonist, as long as the ratio of antagonist to agonist is held constant. This general approach for limiting agonist duration under conditions in which absolute agonist dose is variable should have more general applicability.

• 원예과학기술지
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• 제35권1호
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• pp.88-97
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• 2017

This study explored the physicochemical and nutritional changes associated with storage duration of fresh tomatoes. Fruits of the 'TY Megaton' and 'Yureka' tomato cultivars were harvested at the pink stage and stored at $12^{\circ}C$ for 20 days. During storage, firmness, weight loss, skin color (Hunter L, a, b, a / b values), soluble solids content (SSC), titratable acidity (TA), pH, antioxidant contents (lycopene, ascorbic acid, and total phenolics) and antioxidant activity were evaluated. Firmness was above the minimum marketable limit and fresh weight loss was below maximum acceptable weight loss after 3 weeks of storage, and no deleterious effect on antioxidant contents or activities were observed. Significant differences in SSC, TA, and pH were seen between varieties, but not between fruits stored for different durations. In both varieties, Hunter a values increased more than five-fold after 8 days of storage; this correlated with a more than four-fold accumulation of lycopene after two weeks of storage. The antioxidant activity of tomatoes was highest at the beginning of the storage period, likely because of the effective DPPH - reducing power of ascorbic acid and total phenolics. Antioxidant activity increased after 12 days of storage because of increasing lycopene content. Hence, this study indicates that pink - stage tomatoes may be stored at $12^{\circ}C$ for up to 3 weeks without affecting marketability or nutritional value.

• Korean Journal of Acupuncture
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• 제22권3호
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• pp.17-26
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• 2005

Objectives : The aim of this study is to investigate the effect of Shinmun-acupuncture stimulation on the relationship of change in electrocardiopgraphy (ECG). Methods : For this purpose, 11 healthy volunteers were acupunctured at Shinmun acupoint using the reinforcing or reducing by inserting the needle in the same direction as the channel runs or in the opposite direction (迎隨補瀉). Then, we measured and observed the change of standard leads I, II and III in ECG. Results : In lead I , acupuncture treated groups were increased the activity of PR interval and PR segment compared to the control group. In lead II, during the acupuncture treated group by inserting the needle in the opposite direction as the channel runs was increased the activity of T wave duration, and after the acupuncture group by inserting the needle in the same direction as the channel runs was increased the activity of PR interval. In lead III, acupuncture treated groups were increased the activity of ST duration, PR interval and QT interval. Conclusions : These results suggested that Shinmun acupuncture stimulation plays an important role on the activities of ECG.