• Journal of Ginseng Research
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• 제25권1호
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• pp.37-40
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• 2001

수증기로 찐 다음 뜨거운 물로 추출한 인삼 추출물과 뜨거운 물로만 추출한 인삼 추출물을 대상으로 갈변화 정도와 라디칼 소거활성을 검토하였다. 그결과 수증기로 찌는 것이 물속에서 가열하는 것보다 갈변화 반응이 더 많이 진행되며, 그 추출물의 항산화작용도 더 크다는 것을 알 수 있었다. 이러한 차이는 수삼보다 백삼을 원료로 사용한 경우가 더 큰 것으로 나타났다.

• 약학회지
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• 제19권4호
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• pp.234-239
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• 1975

Protocollagen proline hydroxylase (PPH) activity in the course of rebound of rat carrageenin granuloma was assyed to investigate its relationship with collagen blosynthesis. The specific activity of PPH which was inhibited significantly by treatments with hydrocortisone acetate 93mg/kg/day, 3days) was recovered near to the normal level by 48hr after the cessation of the corticoid treatments. The total enzyme activity of the granuloma of treated group was not yet recovered even on the 3rd day, still showing a significant difference from control. PPH activity expressed in terms of granuloma cells between control and the drug treated group, however, was changed showing no apparent difference throughout the experimental period. These results suggested that the synthesis of protocollagen(collagen precursor) rather than PPH activity was directly affected by administration and withdrawal of corticoid.

• 대한통합의학회지
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• 제11권1호
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• pp.159-166
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• 2023

Purpose : The purpose of this study was to compare the differences in muscle activity of the rectus abdominis, internal oblique, and external oblique muscles according to abdominal muscle exercise methods such as plank exercise, side plank exercise, and crunch exercise. Methods : This study was conducted with 37 college students. All subjects participating in this study were randomly assigned to the plank exercise group, the side plank exercise group, and the crunch exercise group. The exercise corresponding to each group was performed for a total of 8 weeks. The muscle activity of the abdominal muscles was measured before the experiment, 4 weeks, and 8 weeks, and the rectus abdominis, internal oblique, and external oblique muscles were measured. Results : As a result of comparison according to the period in the change in muscle activity of the abdominal muscles after exercise, the amount of change in muscle activity in all three muscles showed a significant difference. As a result of the post-hoc analysis, the muscle activity value of the internal oblique muscle after 4 weeks in the plank exercise showed a significant difference from the value after 8 weeks. In the side plank exercise, the muscle activity values of the rectus abdominis and external oblique muscles before and after 4 weeks showed significant differences from those after 8 weeks. And in the crunch exercise, the muscle activity value of the rectus abdominis muscle before exercise showed a significant difference from the value after 8 weeks. Conclusion : Plank exercise increases the muscle activity of the rectus abdominis, side plank exercise increases the rectus abdominis and external oblique muscles, and crunch exercise increases the muscle activity of the rectus abdominis. Therefore, it is thought that the stability of the trunk can be improved more efficiently if all three exercises are performed.

• Asian-Australasian Journal of Animal Sciences
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• 제31권3호
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• pp.335-343
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• 2018

Objective: Remarkable difference in cellular activity was found between early and late subpassaged embryonic stem cell (ESCs) lines, which can be created by subtle changes in cell manipulation protocol. This study subsequently examined whether post-thaw subculture of early subpassaged ESC lines could further affect the activity of the ESCs. Methods: Fresh (as a control treatment) or cryopreserved F1 hybrid (B6CBAF1) early ESC lines (C57BL/6xCBA) of the 4 (P4) or the 19 passage (P19) were subcultured once, twice or six times under the same condition. The post-thaw survival of the ESCs was monitored after the post-treatment subculture and the ability of cell proliferation, reactive oxygen species (ROS) generation, apoptosis and mitochondrial ATP synthesis was subsequently examined. Results: Regardless of the subculture number, P19 ESCs showed better (p<0.05) doubling time and less ATP production than P4 ESCs and such difference was not influenced by fresh or cryopreservation. The difference between P4 and P19 ESC lines became decreased as the post-treatment subculture was increased and the six times subculture eliminated such difference. Similarly, transient but prominent difference in ROS production and apoptotic cell number was detected between P4 and P19 ESCs only at the 1st subculture after treatment, but no statistical differences between two ESC lines was detected in other observations. Conclusion: The results of this study suggest that post-thaw subculture of ESCs under the same environment is recommended for standardizing their cellular activity. The activity of cell proliferation ability and ATP synthesis can be used as parameters for quality control of ESCs.

• The Journal of Korean Physical Therapy
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• 제33권6호
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• pp.272-277
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• 2021

Purpose: The purpose of this study is to confirm the effect of static stretching of the plantar flexor for 5 minutes on balance and ankle muscle activity when walking in young adults. Methods: This study experimented on 20 healthy college students without vestibular and musculoskeletal diseases. Subjects performed static stretching intervention of plantar flexor for 5 minutes on a stretch board set at 15° to 25° Balance was measured four times before intervention (pre), after intervention (post), 5 minutes after intervention (post 5 min), 10 minutes after intervention (post 10 min), and ankle muscle activity was measured during walking. For the analysis and post hoc analysis, one-way Repeated Measure ANOVA and Fisher's LSD (Last Significant Difference) was performed to find out the change in balance and the activity of ankle muscles before static stretching, pre, post, post 5 minutes rest, post 10 minutes rest. Results: There was no significant difference in weight distribution index (WDI) in balance, but stability index (ST) showed a significant difference, and there was also a significant difference in correlation pre, post, post 5min rest, post 10 minutes rest (p<0.05). There was no significant difference in ankle muscle activity during walking in Tibialis anterior (TA), Medial gastrocnemius (GM), and Lateral gastrocnemius (GL) (p>0.05). Conclusion: The stability index (ST) increased significantly immediately after static stretching and decreased after 5 minutes. After static stretching, at least 5 minutes of rest are required to restore balance.

• The Journal of Korean Physical Therapy
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• 제34권5호
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• pp.278-281
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• 2022

Purpose: This study sought to compare the muscle activity of the deltoid muscle according to the range of motion during the proprioceptive neuromuscular facilitation (PNF) upper extremity D2 pattern exercise performed with an isokinetic exercise device. The aim was to provide basic data for selecting an exercise for the relevant segment of the range of motion to enhance function in clinical practice. Methods: In this study, the relevant measurements of the anterior and middle trapezius of 25 healthy adults were taken using a surface electromyography system. The upper extremity pattern exercise was performed in three ranges (0% to 50%, 50% to 100%, and 25% to 75%) using the upper extremity isokinetic device. Results: There was a statistically significant difference in the muscle activity ratios of the anterior and middle deltoid muscles according to the measurement conditions (p<0.05). There was a statistically significant difference in the activity ratio of the middle deltoid muscle according to the measurement conditions in the ratio from the start range to the end range (p<0.05). There was no significant difference in the muscle onset time difference according to the measurement conditions (p>0.05). Conclusion: The muscle activity of the anterior and middle deltoid muscles was analyzed according to the range of motion during the PNF upper extremity pattern exercise performed with an isokinetic device. The results could be used as a basis for selecting exercises for the relevant segment of the range of motion according to the function to be emphasized.

• Journal of Periodontal and Implant Science
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• 제25권3호
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• pp.529-538
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• 1995

It has been believed that the increased release of free oxygen radicals ($O_2^-,H_2O_2$, and $OH^-$) might be a factor in the pathogenesis of periodontal diseases. Antioxidant enzymes such as glutathione peroxidase(GSH-PX) and catalase can protect the tissue damage from the $H_2O_2$. In order to investigate the GSH-PX and catalase activity in the blood plasma and red blood cells(RBCs) of the patients with periodontitis, 19 patients who had good general health, attachment loss more than 6 mm and bone loss were selected as periodontitis group, 7 patients who had severely inflamed gingiva were selected as gingivitis group, and 15 volunteers with good general and periodontal health were selected as normal group. 17 of 26 patients were performed scaling and root planing to reduce the gingival inflammation for gingivitis and periodontitis groups, and were selected as posttreatment group. After blood plasma and RBCs were collected and separated 1 ml of peripheral blood from each subject, GSH-PX activity in blood plasma and RBCs was measured by the same method that Stefan et al. did, and catalase activity in RBCs was measured by the same method that Beers et al. did. The difference of GSH-PX and catalase activity between normal, gingivitis, and periodontitis groups was statistically analyzed by ANOVA with SPSS/PC+ program, and the difference between pretreatment and posttreatment groups was analyzed by Student t-test. The results were as follows : 1. GSH-PX activity in blood plasma was significantly lower in the gingivitis group($0.8683{\pm}0.0658$), periodontitis group($0.7130{\pm}0.1333$) than in the normal group($1.0241{\pm}0.0801$)(p<0.05), and GSH-PX activity in RBCs was significantly lower in the gingivitis groupt. $0.8156{\pm}0.1167$), periodontitis group($0.7533{\pm}0.1185$) than in the normal group($l.1963{\pm}0.2044$)(P<0.05), but there was no statistical significance in the difference of GSH-PX activity in RBCs between the gingivitis group and periodontitis group(p>0.05). 2. Catalase activity in RBCs was siginficantly lower in the periodontitis group($117.34{\pm}35.01$) than in the normal group($l52.38{\pm}32.09$)(p<0.05). 3. GSH-PX activity in blood plasma was significantly increased in the posttreatment groupe $1.0376{\pm}0.2820$) compared to the pretreatment group(0.7608 0.1600) (p<0.05), and GSH-PX activity in RBC was significantly increased in the posttreatment group($1.0421{\pm}0.2330$) compared to the pretreatment group($0.7728{\pm}0.1210$)(p<0.05). 4. There was no statistical significance in the difference of catalase activity in RBCs between the pretreatment group($112.04{\pm}43.65$) and posttreatment group($l33.41{\pm}39.16$)(p>0.05).The results, within the limits of the present experiment, suggest that the lowered activity of GSH-PX and catalase in blood plasma and RBCs may be related with periodontopathogenesis.

• The Journal of Korean Physical Therapy
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• 제24권5호
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• pp.348-354
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• 2012

Purpose: This study examined the effects of computerized feedback postural training on the balance and electromyography activity of subjects with stroke. Methods: A total of 30 chronic stroke patients were enrolled in this study. Subjects were divided into an experimental group (n=15) and a control group (n=15). Computerized feedback postural training was used in the experimental group. Both groups received intervention for six weeks, 5 times per 30 minutes period. Data analysis was performed using analysis of covariance for determination of statistical significance. Results: Significant difference in static and dynamic balance was observed in the experimental group, compared with the control group (p=0.05), and a significant difference in muscle activity was observed in the gastrocnemius muscle, quadriceps muscle, and elector spinae muscle. However, the hamstring muscle showed no significant difference. Conclusion: Computerized feedback postural training is more effective in improving the ability of balance and muscle activity than neurological physical therapy.

• The Journal of Korean Physical Therapy
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• 제17권1호
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• pp.96-107
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• 2005

Objective: The purpose of this study were to investigate the standing balance, dynamic activity in hemiplegic patients according to the types of ankle-foot orthosis(AFO) and to determine the most effective type of AFO for gait training. Method: A prospective study was performed for 16 patients with hemiplegia who was able to walk independently. Static balance and dynamic activity were compared in two condition : 1) barefoot and SPAFO, 2) barefoot and HPAFO. Static balance and dynamic activity characteristics were evaluated by Active Balance while they were standing with in two condition AFO and barefoot. Results: There were significant difference in standing balance between barefoot and wearing SPAFO and HPAFO(p<0.05). There were significant difference in dynamic activity balance between barefoot and wearing SPAFO and HPAFO(p<0.05). There were significant difference in gait speed between barefoot and wearing SPAFO and HPAFO(p<0.05). Conclusion: This study showed that wearing SPAFO and HPAFO gave fair amount of improvement to balance and gait ability of hemiplegic patients.

• The Journal of Korean Physical Therapy
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• 제17권4호
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• pp.621-631
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• 2005

The purpose of this study was to measure magnitude of lower leg muscle activity during dynamic stability tests performed on an unstable board by subjects with sprained lateral ankles. Fifteen lateral ankle sprain subjects(8 male, 7 female) participated in this study. The muscle activity was measured at gastrocnemious, tibialis anterior, peroneus longus during dynamic stability tests performed on Biodex stability system as surface EMG. The EMG amplitude of each muscle was normalized to the amplitude in the maximal voluntary isometric contraction(MVIC) of each muscle. As results, peroneus longus evidenced significant difference at stable and unstable grade comparing injured with uninjured sides. Gastrocnemious and tibialis anterior evidenced no significant difference. Change of muscle activity with stable and unstable grade evidenced no significant difference on injured and uninjured sides. The data provided information on peroneus longus contributes to dynamic stability after lateral ankle sprains. Peroneus longus training program may have to be emphasized after an ankle sprain.