The immunopotenciating effects of petroleum ether extract, ethanol extract and butanol fraction of panax ginseng on the immunotoxicity of Cimetidine were investigated in ICR mice. Immune responses were evaluated by antibody production, Arthus reaction, delayed type hypersensitivity (DTH), and rosette forming cell (RFC) in mice, sensitized and challenged with sheep red blood cells. To investigate the change of the non-specific immune responses, phagocyte activity and number of leukocytes in peripheral blood were measured also. The results of this study are summarized as followings; 1. Cimetidine treated group as compared with normal group generally decreased HA, 2-MER, RFC, number of circulating leukocytes and phagocyte activity whereas in-creased Arthus reaction and DTH. 2. The panax ginseng petroleum ether extract combined administration group as compared with the control group remarkably increased HA, 2-MER, number of circulating leukocytes and phagocyte activity. 3. The panax ginseng ethanol extract combined administration group as compared with the control group remarkably increased Arthus reaction, DTH, HA, RFC, number of circulating leukocytes and phagocyte activity. 4. The panax ginseng butanol fraction combined administration group as compared with the control group remarkably increased Arthus reaction, HA, 2-MER, RFC, number of circulating leukocytes and phagocyte activity.
Several serum enzyme activities were measured after intraBeritoneal administration of 0.01 ml $CCl_{4}$ per 100 g of body weight in Sprague Dawley rats. Senun AST activity increased significantly after administration of CCl$_{4}$ (P<0.05). The serum AST activity at 2 hours after $CCl_{4} administration (475 {\pm} 10^{6} IU/L)$ was significantly higher than that of control group $(65 {\pm} 14 IU/L)$. The high level of serum AST activity maintained up to 48 hours. Serum ALT activity in $CCl_{4}$-treated groups was also significantly higher from 4 hours after treatment companied to control group and the high level maintained up to 48 hours. Serum ALP and ${\gamma} GTP activities in CCl_{4}$-treated groups were significantly higher from 8 hours after treatment compared to control group and the level maintained up to 48 hours.
The purpose of this study was to investigate whether the extracts of Daucus carota L. could lead to a beneficial outcomes on serum lipid and antioxidative enzyme activity in ovariectomized rats. Sprague-Dawley rats were randomly assigned to one control and three diet groups; carrot seed, carrot root and estrogen after ovariectomy operation. Experimental diets were fed for 8 weeks. The GOT activity was decreased in the carrot extracts treated group than in the control group. The carrot seed extracts treated group showed the lowest SOD and catalase activities compare to other groups. Serum total cholesterol and LDL cholesterol decreased in the carrot seed extracts group than in the control group. From these results, it suggest that carrot seed extracts positively influenced on serum lipid and antioxidative enzyme activity.
In order to study the effects of Daebangpungtang on galactosamine induced hepatoxity in rats, the experimental rats divided five groups (Normal, Control, Sample A, B, C groups). Under the same condition, normal and control groups were administered normal saline for 16 days, control group was injected to abdomen with galactosamine at 8th day (800mg/kg). Sample A group was administered the Daebangpungtang aqueous solution($200m{\ell}/kg$ p.o) for 8 days and injected galactosamine(800mg/kg i.p) for the last day and was administered normal saline for 8 days. Sample B group was treated as same as group A for 8 days, and then was administered the Daebangpungtang aqueous solution($200m{\ell}/kg$ p.o) forfurther 8 days. Sample C group was administered the Daebangpungtang aqueous solution($200m{\ell}/kg$ p.o) for 16 days. The activity of GOT, GPT, ${\gamma}$-GTP, ALP, LDH and total bilirubin in serum were measured at 8th and last day. The results were obtained as follows: 1. The activity of serum GOT of the sample A group decreased effectively at the 8th day and sample B group decreased effectively at 16th day as compared with the control group. 2. The activity of serum GPT of the sample A group decreased effectively at the 8th and 16th day and sample B group decreased effectively at 16th day as compared with the control group. 3. The activity of serum ${\gamma}$-GTP of the sample B group decreased effectively at the 16th day as compared with the control group. 4. The activity of serum ALP of the sample A group increased respectively at the 8th and 16th day and sample B group decreased effectively at 16th day as compared with the control group. 5. The activity of serum LDH of the sample A, B groups decreased effectively at 16th day as compared with the control group. 6. The activity of serum total bilirubin of the sample A, B groups decreased effectively at 16th day as compared with the control group. 7. The activity of GOT, GPT, ${\gamma}$-GTP, ALP, LDH and total bilirubin in serum of the sample C group were analogous with thats of normal group.
The 3th International Conference on Construction Engineering and Project Management
/
pp.1100-1106
/
2009
General contractors' overhead costs are increasing relative to direct costs. However, it is difficult to apply the traditional activity-based costing directly to the construction site overhead costing because the resource consumption rate per each activity is varied depending on the attributes of activities. The research develops a methodology of hybrid cost allocation system when resources are assigned to cost objects unlike the traditional activity-based costing. The study also develops a database program and demonstrates how it can be applied to the construction projects using a case study.
Due to the increasing complexity to handle conflicts and interruptions caused by resource failures and rush orders, shop control is obliged to redesign its organization according to the changing demands of the manufacturing control. These demands are leading to the development of decentralization and gradually to their permanent optimization. As a result, a powerful modeling method which can be adapted efficiently is required. The use of agent theory enables specific modeling of the relevant shop planning activities. The planning activities are modeled in a so-called activity modeling through the definition of three classes of agents; Plan Agent, Manufacturing System Agent and Control Agent as well as the description of the cooperative relationship among these agents. On the basis of the activity model the agent-based shop control method is developed which emphasizes the distributed problem-solving and the cooperation with relevant agents.
To investigate the radiation effect of P-32 on the soybean plants, the seeds treated with various levels of P-32 solution were sown and cultured in the pots. The growth of the plants and the contents of the macroelements were observed and the following results were obtained. 1) The linear growth of the plants at the early stage seemed to have been promoted by the low-level P-32 treatemnt. At the later growing stage, however, this difference among treatments were less conspicuous. 2) The plants of high level P-32 application showed some growth damaging symptom at the early growing stage. Later this damage was recorded as the time went on and these plants showed even better growth than the control. As a result at the late growing stage, they ensued highest growth. 3) The plants showed in general more growth at the low activity level than at the high-level at the early growing stage. At the late stage, however, the high-level activity promoted more growth than the low-level. 4) At the early growing stage P-32 treatment produced in general significantly more lower than control. At the later stage, however, this difference was not clearly seen. 5) The P-32 treatment seemed to have stimulated earlier florescence and this tendency was more clearly observable eapecially at the high activity level. 6) The weight of the air-dried seeds tended to be increased through P-32 treatment by 10-45%. This tendency was clearly observed especially at the low-level activity. 7) As for the contents of the various macroelements in the leaves, the nitrogen showed significantly larger contents at the middle level(S1) P-32 treatments. The phosphorous contents showed also highest at the middle levels activity and lower both at the high and low-activity levels. The potassium contents was proved, on the contrary, higher at the low-level activity and lower at the high-level. 8) The nitrogen contents in the stems was found significantly higher than control, except at the low-activity level. The phosphorous showed higher contents at the low-activity level and no significant difference at the high-activity level. As for the contents of potassium, calcium and magnesium, three seemed no significant difference among treatments. However, the magnesium showed somewhat higher content at the low-activity level, whereas the calcium was proved high than control. 9) The inorganic contents in the root showed that N and P in the P-32 treated plant were significantly higher than the control and the K-contents was, on the contrary, significantly higher at the control than the rest of the treatments. As for the calcium and magnesium there showed no difference among all treatments.
To study the effects of metal ions on the activity of anti-oxidase enzymes, the activity of superoxide dismutase (SOD) and peroxidase (POD) and isozyme patterns of Brassica juncea have been studied after treating with CD, Cu, Zn, and Al. The activity of SOD after treating with metal ions was higher than that of untreated control. SOD activity in leaves increased by treatment of 50 ppm of Zn and 500 ppm of Al. POD in stems gave highest activity after treating with 500 ppm of Cu. When the activity was compared by plant parts, lowest POD activity was observed in leaves in which protein content was higher than other tissues. When the activity was expressed as percentage of control, SOD activity was increased after treating with metal ions. SOD activity in leaves and roots of metal treated plant was significantly increased under the metal ions stress conditions. In the roots of 50 ppm of Zn treated plant, SOD activity was extremly high. POD activity was inhibited with Cd and Zn treatment in all parts of the plant. However, in leaves and stems, there was marked increase in activity after treating with Cu. The patterns of SOD isozyme after metal treatment show that two bands were stained in all metal ion treated and that no new band appeared. POD isozyme band intensity resulting from the treatment of metal ions was in order of roots > stems > leaves, but there was no significant difference.
The effects of different concentrations of three amino acids as carbon and or nitrogen sources on mycelial dry weights, changes in pH values of synthetic medium, ammonia secretion and extracellular protease activity by three zoosporic fungi, pathogens of fish and shellfish, were studied. As compared with the control, the addition of isoleucine and aspartic acid as nitrogen sources were generally stimulative for mycelial dry weight production whereas phenylalanine was inhibitory irrespective to the tested fungal species. When amino acids served as carbon and nitrogen sources, the mycelial dry weights of the three fungi were increased (mostly non-significantly) relative to untreated control but weights were decreased as the concentrations of the three amino acids raised. The addition of individual amino acids as carbon and nitrogen sources to the medium significantly increased pH values of the medium comparable to the control. The addition of each of the three amino acids as carbon and nitrogen sources to the medium significantly induced ammonia secretion by the three species of zoosporic fungi. Ammonia secretion in synthetic medium amended with amino acids as nitrogen source raised by the three zoosporic fungi relative to untreated control except in case of Achlya racemosa treated with isoleucine. Extracellular protease activity was almost promoted in case of Achlya proliferoides and Saprolegnia furcata cultures treated with isoleucine and aspartic acid individually in presence of glucose and vice versa in case of phenylalanine. However, extracellular protease activity of A. racemosa decreased compared with the control at various concentrations of isoleucine and both phenylalanine and aspartic acid assumed inconsistent effects. Extracellular protease activity of the three zoosporic fungi in the medium devoid of glucose varied depending upon zoosporic fungal species, the tested amino acid and the applied concentrations. The values of protease activity were approximately less two folds than that obtained in presence of glucose.
Purpose : The purpose of this study is to determine the effects of high heeled shoes on the static balance and EMG activity of lower extremity muscles. Methods Twenty subjects were composed of control group(wearing low-heeled shoes) and experimental group(wearing high-heeled shoes). Two groups participated in bearfoot standing and measured static balance and EMG activity of lower extremity muscles. Balance Performance Monitor(BPM) was used to measure the static balance and FlexComp $Infiniti^{TM}$ was used to measure the EMG activity of lower extremity muscles. Results In static balance, sway area and path of experimental group was significantly larger than control group(p<0.05). And sway velocity of experimental group was significantly faster than control group(p<0.05). They means static balance of experimental group was significantly lower than control group(p<0.05). In EMG activity, L5 paraspinalis and biceps femoris of experimental group was significantly more increased than that of control group(p<0.05). Conclusion : The long-time experience in wearing high heeled shoes may have caused change in static balance and EMG activity of lower extremity muscles.
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