• Electrical & Electronic Materials
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• v.7 no.5
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• pp.376-382
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• 1994

In this study we developed a program(DEVSIM) to simulate the two dimensional distribution of the electrostatic potential and the electric field of the arbitrary structure consisting of GaAs/AlGaAs semiconductor and metal as well as dielectric. By the comparision of the electric field distribution of GaAs MESFETs with the various recess gates we proposed a suitable device structure to improve the breakdown characteristics of MESFET. According to the results of simulation the breakdown characteristics were improved as the thickness of the active epitaxial layer was decreased. And the planar structure, which had the highly doped layer under the drain for the ohmic contact, was the worst because the highly doped layer prevented the space charge layer below the gate from extending to the drain, which produced the narrow spaced distribution of the electrostatic potential contours resulting in the high electric field near the drain end. Instead of the planar structure with the highly doped drain the recess gate structure having the highly doped epitaxial drain layer show the better breakdown characteristics by allowing the extention of the space charge layer to the drain. Especially, the structure in which the part of the drain epitaxial layer near the gate show the more improvement of the breakdown characteristics.

• Journal of the Institute of Convergence Signal Processing
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• v.1 no.1
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• pp.23-31
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• 2000

Iterative curve evolution techniques are powerful methods for image segmentation. Classical methods proposed curve evolutions which guarantee close contours at convergence and, combined with the level set method, they easily handled curve topology changes. In this paper, we present a new geometric active contour model based on level set methods introduced by Osher & Sethian for detection of object boundaries or shape and we adopt anisotropic diffusion filtering method for removing noise from original image. Classical methods allow only one-way curve evolutions : shrinking or expanding of the curve. Thus, the initial curve must encircle all the objects to be segmented or several curves must be used, each one totally inside one object. But our method allows a two-way curve evolution : parts of the curve evolve in the outward direction while others evolve in the inward direction. It offers much more freedom in the initial curve position than with a classical geodesic search method. Our algorithm performs accurate and precise segmentations from noisy images with complex objects(jncluding sharp angles, deep concavities or holes), Besides it easily handled curve topology changes. In order to minimize the processing time, we use the narrow band method which allows us to perform calculations in the neighborhood of the contour and not in the whole image.

• Journal of Korea Multimedia Society
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• v.10 no.9
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• pp.1117-1124
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• 2007

In this paper, an algorithm that can define the threshold value automatically proposed in order to detect a brain ventricle in MRI brain images. After the wavelet transform, edge sharpness, which means the average magnitude of detail signals on the contour of the object, was computed by using the magnitude of horizontal and vertical detail signals. The contours of a brain ventricle were detected by increasing the threshold value repeatedly and computing edge sharpness. When the edge sharpness became maximal, the optimal threshold was determined, and the detection of a brain ventricle was accomplished finally. In this paper, we compared the proposed algorithm with the geodesic active contour model numerically and verified the efficiency of the proposed algorithm by applying real MRI brain images.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.1
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• pp.26-32
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• 2023

Dental trauma is common in active children and adolescents. Among them, in the case of ankylosis due to avulsion, diagnosis through clinical examination is important, and the treatment is important for esthetic prosthetic restoration after adulthood. This case is a case of esthetic prosthetic restoration of maxillary anterior teeth through decoronation and implant. After that, space was maintained for prosthetic restoration using a decoronated crown. After becoming an adult, precise implant placement and esthetic prosthetic restoration were possible using guide surgery. For soft tissue support, the temporary crown were replaced by changing the contours of the temporary crown, and the final esthetic prosthesis was fabricated by digital wax-up.

• Journal of the Korea Computer Graphics Society
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• v.23 no.1
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• pp.49-55
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• 2017

Computed tomographic angiography (CTA) is widely used in the diagnosis and treatment of coronary artery disease because it shows not only the whole anatomical structure of the cardiovascular three-dimensionally but also provides information on the lesion and type of plaque. However, due to the large size of the image, there is a limitation in manually extracting coronary arteries, and related researches are performed to automatically extract coronary arteries accurately. As the coronary artery originate from the ascending aorta, the ascending aorta and ostium should be detected to extract the coronary tree accurately. In this paper, we propose an automatic segmentation for the ostium as a starting structure of coronary artery in CTA. First, the region of the ascending aorta is initially detected by using Hough circle transform based on the relative position and size of the ascending aorta. Second, the volume of interest is defined to reduce the search range based on the initial area. Third, the refined ascending aorta is segmented by using a two-dimensional geodesic active contour. Finally, the two ostia are detected within the region of the refined ascending aorta. For the evaluation of our method, we measured the Euclidean distance between the result and the ground truths annotated manually by medical experts in 20 CTA images. The experimental results showed that the ostia were accurately detected.

• The Korean Journal of Pharmacology
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• v.32 no.3
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• pp.425-431
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• 1996

Human neutrophil elastases (HNElastase, EC 3.4.21.37), a causative factor of inflammatory diseases, are regulated by plasma proteinase inhibitors, alpha-proteinase inhibitor and ${\alpha}_2-macroglobulin$. Under certain pathological conditions, however, released enzymes or abnormal function of inhibitors may cause various inflammatory disease. NSAIDs have been clinically applied for treatment of inflammatory diseases. Inhibition of cyclooxygenase is a known mechanism of action of NSAIDs in the treatment of inflammatory disease. In in vitro experiments, HNElastase was inhibited by naproxen, phenylbutazone, and oxyphenbutazone, but ibuprofen, ketoprofen, aspirin, salicylic acid, and tolmetin did not inhibit elastase. HNElastase was also inhibited by chelating agents, EDTA & EGTA, and tetracyclines. Removal of divalent metal ions by EDTA caused inhibition of elastase, and reconstitution of the metal ions recovered the enzyme activity to a certain level. Frequencies and contours in the Raman spectra of various conditions of human neutrophil elastase undergo drastic changes upon partial removal and/or reconstitution of calcium and zinc ions. The metal ion content dependent activities and change of the contour of the Raman spectrogram suggest us that the mechanism of action of a chelator or chelator-like agents on neutrophil elastase may be related to the conformational change at/or near the active site, especially -C=O radical or -COOH radical.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.4
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• pp.101-109
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• 2014

It is an essential element for the establishment of image processing related systems to find the exact contour from the image of an arbitrary object. In particular, if a vision system is established to inspect the products in the automated production process, it is very important to detect the contours for standardized shapes such lines and curves. In this paper, we propose a prototype adaptive dynamic contour model, p-Snake with improved contour extraction algorithms by adding the prototype energy. The proposed method is to find the initial contour by applying the existing Snake algorithm after Sobel operation is performed for prototype analysis. Next, the final contour of the object is detected by analyzing prototypes such as lines and circles, defining prototype energy and using it as an additional energy item in the existing Snake function on the basis of information on initial contour. We performed experiments on 340 images obtained by using an environment that duplicated the background of an industrial site. It was found that even if objects are not clearly distinguished from the background due to noise and lighting or the edges being insufficiently visible in the images, the contour can be extracted. In addition, in the case of similarity which is the measure representing how much it matches the prototype, the prototype similarity of contour extracted from the proposed p-ACM is superior to that of ACM by 9.85%.

• Journal of Dental Rehabilitation and Applied Science
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• v.16 no.2
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• pp.149-159
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• 2000

Occlusal disease is comparable to periodontitis in that it is generally not reversible. Occlusal disease, however, like periodontitis, often maintainable. It does itself to treatment and when restorative dentistry is utilized it becomes, in that sense, reversible. Moreover, a systematized and integrated approach will lead to a prognosis that is favorable and predictable. This approach facilitates development of optimum oral function, comfort, and esthetics, resulting in a satisfied patient. Such a systematized approach consists of four logical phase : (1) patient evaluation, (2) comprehensive analysis and treatment planning, (3) integrated and systematic reconstruction, and (4) postoperative maintenance. An integrated treatment plan is first developed on one set of diagnostic casts, properly mounted on a semiadjustable articulator using jaw relationship records. This is accomplished by using wax to make reconstructive modifications to the casts. These modified casts become the blueprint for planned occlusal changes and the fabrication of provisional restorations. The treatment goals are : (1) comfortably functioning temporomandibular joints and stomatognathic musculature, (2) adherence to the basic principle of occlusion advocated by Schuyler, (3) anterior guidance that is in harmony with the envelope of function, (4) restorations that will not violate the patient's neutral zone. This report shows the treatment procedures for a patient whose mandibular position has been altered due to posterior bite collapse. Migration of the maxillary anterior teeth had occurred, and the posterior occlusal contacts showed pathologic interference. Precise diagnosis using mounted casts was executed and prosthodontic reconstruction by the aid of an unconventional orthodontic correction on maxillary flaring was planned. An unconventional orthodontic correction can be accomplished by using preexisting natural teeth, which can be modified for use in active tooth movement or splinted together for orthodontic anchorage. This technique has an advantage over conventional fixed appliance orthodontic therapy because it can accomplish tooth movement concurrently with restorative and periodontal therapy. On occasion, minor tooth movement can be necessary to achieve the optimum occlusal scheme, crown form, and tooth position for the forces of occlusion to be displaced down the long axis of the periodontally compromised teeth. Once the occlusion, periodontal health, and crown contours for the provisional splinted restoration are acceptable, the final splinted restoration can be similarly fabricated, and it becomes an excellent orthodontic retainer.