• 제목/요약/키워드: Active Treatment

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The Design of Photobiological Active Molecular Model For Photodynamic Therapy

  • Choi, Chang-Shik
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2019년도 춘계학술대회
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    • pp.521-524
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    • 2019
  • The design of photobiological active photosensitizing molecular model for photodynamic therapy has been attracted as a research for the development of cancer treatment, and has been interested in the effective method for cancer treatment and the photosensitizer having more stable wavelength. Furthermore, the development of photosensitizer has been already carried out from the first generation molecule to the third one, and the research of smart photosensitizer as the fourth generation has been requested. As a fact, the selective killing of the only cancer cell is very difficult problem, and the present photodynamic therapy has the problem of killing of the normal cell. So, I have designed the new modelling of photosensitizer having the smart recognizing unit and the magnetic nanoparticle as well as having the several effective recognizing unit. In particular, the new model design of the photosensitizer having lanthanide metal has suggested for the development of photodynamic therapy. The model design of these new photosensitizing molecules will be introduced in the poster section for the new turning point of the development of photosensitizer.

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박하(薄荷)의 국내·외 연구동향과 『본초학』, 한국표준질병사인분류의 상관관계에 대한 연구 (The Literature Study of Research Trend of Menthae Herba and Relationship Between the Herbology and KCD-code)

  • 김현석;정종길;이숭인
    • 대한본초학회지
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    • 제30권5호
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    • pp.29-43
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    • 2015
  • Objectives : This study was aimed to analyze the correlation between the Herbology and contemporary research results, KCD-codes.Methods : Papers were searched in OASIS and PubMed, then they were categorized. Medicine or pharmacy articles about Menthae Herba were matched with the Herbology treatment and KCD-codes. Other articles were analyzed by abstract of the papers. KCD-codes and terms were arranged by the Herbology treatment. The Degree of Herbology research (HDR) was calculated by numbers of papers, study method, citation rates.Results : There were 97 articles about Menthae Herba. Among these there were 47 medicine and pharmacy articles about Menthae Herba, and 15 articles were matched to the Herbology treatment. Studies about Headache and Wind-warmth was more active than others. Analysis of other articles showed that studies about contraceptive and anti-oxidative effect, plant growth, protective effect from insect, component extraction technics were active, too. In HDR, headache was scored by 136, Wind-warmth by 104, Eye hemorrhage by 51, Discomport in the throat by 50, Distention and fullness in the chest and hypochondrium by 15, Rubella and Measles by 0.Conclusions : 97 articles about Menthae Herba were analyzed and 15 articles were matched to the Herbology treatment. Studies about headache, wind-warmth, eye-hemorrhage were more active than others of the Herbology treatment. And studies about contraceptive and anti-oxidative effect, plant growth, protective effect from insect, component extraction technics could be a new subject of the Herbology.

상완 신경총 손상후 주관절 근력 회복을 위한 광배근 전이술 (Latissimus Dorsi Transfer in Brachial Plexus Injury for the Elbow Flexion)

  • 한정수;정덕환;소재호
    • Archives of Reconstructive Microsurgery
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    • 제7권1호
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    • pp.35-40
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    • 1998
  • The incidence of brachial plexus injury is increasing because of the development of motor vehicle but the the results of treatment was reported poor due to its complex anatomical structure and changes of function and sensory during the recovery after trauma. But the results of treatment has been improved by the recently introduced high sensitive diagnostic method that can evaluate accurately the site and extent of the injury and treatment method. Restoration of the elbow flexion is the most important goal of treatment after brachial plexus injury and nerve graft, neurotization and muscle transfer were used for methods of treatment. From December 1992 to May 1994, the author performed 6 cases of latissimus dorsi transfer at the same side for the improvement of elbow flexion in the patients of brachial plexus injury. There were 5 cases of male, one case of female and average age was 22 years old. The causes of injury were traffic accident in 3 cases, gun shot injury, falldown and birth injury in each one case and in all cases, the type of injury were upper arm type. The average follow up period were 1 year 5 months ranging from 12 months to 4 years 5 months. In all cases, active elbow flexion was impossible before operation and average muscle power was grade I. We analysed the active range of motion, muscle power and the functional results. At the last follow up, range of active elbow flexion was average $124^{\circ}$ and flexion contracture was average 11 degrees and the average of muscle power was grade IV. In the functional analysis, there were two cases of excellent, three cases of good and 1 case of fair. There was no complications including wound infection, vascular compromise and donor site problem. The results of latissimus dorsi transfer for improvement elbow flexion in the patients of brachial plexus injury is one of the useful mettled for the restoration of elbow flexion.

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TUBERCULOSIS TRANSMISSION MODEL WITH CASE DETECTION AND TREATMENT

  • Bhunu, C.P.;Mushayabasa, S.;Magombedze, G.;Roeger, L.I.
    • Journal of applied mathematics & informatics
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    • 제29권3_4호
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    • pp.529-546
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    • 2011
  • A deterministic tuberculosis model for theoretically assessing the potential impact of the combined effects of case detection in the presence of treatment is formulated. The qualitative features of its equilibria are analyzed and it is found that the disease-free equilibrium may not be globally asymptotically stable when the reproduction number is less than unity. This disease threshold number is further used to assess the impact of active TB case finding alone and in conjunction with treatment. A critical threshold parameter ${\Theta}$ say for which case detection will have a positive impact is derived. Using the Centre Manifold theory, the model may exhibit the phenomenon of backward bifurcation (coexistence of a locally stable endemic equilibrium with a stable disease-free equilibrium) when the reproduction number is less than unity. It is shown that the possibility of backward bifurcation occurring decreases with increase case detection. Graphical representations suggest that increase in case finding accompanied by treatment of detected TB cases, result in a marked decrease of TB cases (both latent and active TB).

하수와 소화슬러지의 $CH_4$가스 배출원단위 산정에 관한 연구 (Estimate of $CH_4$ Emission Factors in Municipal Wastewater Treatment Plants)

  • 양형재;박정민
    • 환경위생공학
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    • 제23권3호
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    • pp.39-46
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    • 2008
  • In order to study the estimate of $CH_4$ emission factors in the municipal wastewater treatment plants, the active sludge process, 5-stage process, Denipho process, and SBR process were investigated. When active sludge process, 5-stage process, and Denipho process were used in wastewater treatment plant, the $CH_4$ emission factors were 2.88, 1.61, and 0.57 g-$CH_4/kg$-BOD, respectively. On the other hand, in the case of SBR process, it was 4.14 g-$CH_4/kg$-BOD. These results indicate that SBR process was effective for $CH_4$ emission in municipal wastewater treatment plants. Using the above processes, the methane emission factor and amount of waste water sludge were $4.78m^3/t$ and $12,204,506m^3/yr$, respectively. The remove of BOD was a range of $93.91{\sim}98.63%$.

경골 고평부 골절 후유증에 능동이완기법을 병행한 한방치료 호전 2예 (Two Clinical Cases of Active Release Technique with Oriental Medicine Treatments for Sequlae of Tibial Plateau Fracture)

  • 이성준;박재현;김병정;강준혁;김효섭;송병재
    • 한방재활의학과학회지
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    • 제23권3호
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    • pp.201-210
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    • 2013
  • 상기 증례에서 저자는 경골 고평부 골절 후유증 환자에게 ART를 적용하여 Lysholm knee scoring scale, 슬관절 및 족관절 ROM, VAS 평가를 통해 다음과 같은 결론을 얻었다. 1. 경골 고평부 골절 이후 하지부 및 슬부 통증, 족관절과 슬관절 ROM 제한으로 보행 장애 발생한 환자에게 ART 치료를 적용하여 Lysholm knee scoring scale, 슬관절 및 족관절 ROM, VAS에서 현저한 개선 보인 것을 확인할 수 있었다. 2. 비교적 증례가 많지 않고 한방적 치료 과정이 정립되어 있지 않은 경골 고평부 골절 후유증에 ART 치료가 유의한 효과가 있음을 알 수 있었다.

능동구속감쇠 기법을 이용한 복합적층보의 진동 제어 (Vibration Control of Laminated Composite Beams Using Active Constrained Layer Damping Treatment)

  • 강영규;최승복
    • 한국소음진동공학회논문집
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    • 제11권7호
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    • pp.261-266
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    • 2001
  • The flexural vibration of laminated composite beams with active and passive constrained layer damping has been investigated to design a structure with maximum possible damping capacity. The equations of motion are derived fro flexural vibrations of symmetrical,. multi-layer laminated beams. The damping ratio and model damping of the first bending mode are calculated by means of iterative complex eigensolution method. The direct negative velocity feedback control is used for the active constrained layer damping. It is shown that the flexible laminated beam is more effective in the vibration control for both active and passive constrained layer damping. and this paper addresses a design strategy of laminated composite under flexural vibrations with constrained layer damping.

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침(鍼) 자극(刺戟)이 중풍환자(中風患者)의 보행개선에 대한 임상적 관찰 (Clinical Trials For Gait Rehabilitation of Stroke Patients by the Acupuncture Treatment)

  • 신승우;황지식;신현대;이상학
    • 대한추나의학회지
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    • 제3권1호
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    • pp.55-64
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    • 2002
  • Objectives : Acupuncture therapy is known as a effective method to CVA with paralysis. To make clear about effectiveness of acupuncture affecting to active and static postural adaptation for the patient with hemiparesis, we studied whether acupuncture changed ability of maintenance with one leg standing posture, and character of gait such as gait velocity, cadence, stride length, step length and base of support. Methods : This clinical study has been carried out with 10 cases of CVA patient with hemiparesis. We treated patients with acupuncture for 4 weeks, estimated each paralytic leg and well leg before 1st treatment and after last treatment, and compared the change of one leg with the other. To estimate the change of ability of static postural adaptation, we checked the time of duration with one leg standing posture. And about active postural adaptation, we used temporal distance gait analysis with Ink-Foot-Print method. Results and Conclusions : In static postural adaptation, paralytic leg significantly improved the duration with one leg posture. And In active postural adaptation with gait analysis, paralytic leg showed significant improvement in stride length and step length. Base of support and cadence were also significantly improved.

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Active biotelemetry를 이용한 젖소의 스트레스 반응 측정: II. 수송 스트레스 감소를 위한 수액투여 효과 (Measuring stress responses using active biotelemetry in cattle II. Fluid administration for reducing transport stress)

  • 이수한;이병한;임좌진;김진영;이동희;김재경;최농훈;정순욱;정병현
    • 대한수의학회지
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    • 제41권4호
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    • pp.603-609
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    • 2001
  • A transport stress is one of the main causes of economic losses and physiological dysfunction. The present study has been performed to suggest a method to decrease the adverse effects above mentioned from transport. The groups were prepared as follows; (1) Control group : 4 cattle transported for 5 hrs (274 km) without any treatment, (2) Treatment group : 4 cattle treated with electrolyte-mineral solution (I.V.) at 1 hr before the enrollment of transport under same experimental condition with Control group. The blood specimens were collected at 1 hr before transport, 2.3 hrs (135 km) and 5 hrs (274 km) after the enrollment of transport, and 1, 6 and 18 hrs after fulfillment of transport. The collected blood specimens were analyzed for cortisol and epinephrine. Core temperature and heart rate were measured with active biotelemetry in every 30 minutes from 0.5 hr before the start of transport to 18 hrs after the end of transport. In results, the level of cortisol considerably increased to the peak either in Control group ($5.3{\pm}1.3{\mu}g/d{\ell}$) and in Treatment group ($4.0{\pm}2.6{\mu}g/d{\ell}$) at 2.3 hrs in transport. The concentration of epinephrine of Treatment group had been higher than that of Control group from the start of transport to 18 hrs after the fulfillment of transport. Particularly there was the biggest gap between Control and Treatment groups, $424.0{\pm}194.1pg/m{\ell}$ and $209.1{\pm}65.1pg/m{\ell}$ respectively, at 6 hrs after the end of transport. The heart rates were considerably increased either in Control group ($81.5{\pm}18.5$ to $126.3{\pm}7.8beats/min$) and in Treatment group ($114.3{\pm}14.4$ to $140.8{\pm}22.4beats/min$) with the enrollment of transport. These results indicate that the concentration of cortisol and the heart rate were pertinent to cognitive parameters to evaluate physiological responses against stress such as transport. In addition, the intravenous administration of electrolyte-mineral solution could be suggested as the method to decrease the adverse effects from a transport stress.

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