• 성인간호학회지
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• 제21권4호
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• pp.435-445
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• 2009

Purpose: This study was to examine whether VRE infection control strategies have an effect on the decrease in incidence rates for VRE acquisition and VRE nosocomial infection in ICU. Methods: All the patients were examined for VRE carriers on ICU admission. Among them, patients hospitalized for over 48 hours were investigated for VRE acquisition rates and VRE nosocomial infection rate using VRE infection control strategies in ICU for the experimental group from September 2007 to April 2008. Before that, incidence of VRE acquisition and VRE nosocomial infection for the control group without Intervention were investigated from May to August 2007 retrospectively. Results: VRE acquisition rate in clinical specimens was 0.6% in the experimental group, that was significantly lower when compared to the control group. VRE carrier rate at admission to ICU was 15.4%. Out of 182 VRE carriers, 180 patients were identified by the active surveillance culture. Conclusion: These results suggested that active surveillance culture at admission was considered to be an essential measure for detection of VRE carrier. But without strict isolation and adherence rating after each intervention, hand washing and contact isolation alone did not significantly decrease VRE nosocomial infection, although it did significantly decrease incidence of VRE acquired from clinical specimen.

• Journal of Preventive Medicine and Public Health
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• 제40권4호
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• pp.278-284
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• 2007

Despite extensive researches and pre-market clinical trials, only limited information on the adverse drug reactions (ADRs) of a drug can be collected at the time of market approval from regulatory agency. ADRs constitute a major public health problem. Post-marketing surveillance of drugs is important to detect signals for ADR. In Korea, one of the main methods for monitoring the safety of marketed drugs is spontaneous reporting system of suspected ADRs. Re-examination and re-evaluation system are in force for monitoring safety of new market approval drugs and currently under marketing drugs, respectively. Recently, regional pharmacovigilance centers were designated from Korean Food and Drug Administration for facilitating ADR surveillance. Over recent years, with the development of information technology, there has been an increased interest in establishing data mining system for detecting signals from Health Insurance Review Agency database. The purpose of this paper is to review the current status of Korean ADR surveillance system and suggest the possible solutions for developing active pharmacovigilance system in Korea.

• 기본간호학회지
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• 제15권4호
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• pp.522-530
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• 2008

Purpose: In this study active surveillance culture for ICU patients, in whom the risk of VRE infection was high were conducted, and through this the VRE colonization rate and the characteristics of the colonization were examined and risk factors involved in VRE colonization and acquisition were analyzed. Method: This research was performed with 635 patients admitted to ICU between July 1 and December 31, 2006. Results: On admission to ICU, the VRE colonization rate was 2.36%, 93% identified from active surveillance culture. The VRE colonization rate was significantly higher in those patients with cancer (OR=9.43; 95% CI=1.38${\sim}$62.50; P=.022), liver cirrhosis (OR=55.5; 95% CI=7.29${\sim}$500; P=.005), transferred from other hospitals (OR=200; 95% CI=22.73${\sim}$1000; P=.000), high APACHE II score (OR=1.107; 95% CI=1.010${\sim}$1.213; P=.029), or antibiotics within the last 3 months (OR=15.87; 95% CI=2.27${\sim}$111.11; P=.005). The VRE acquisition rate was 5.2%. It was significantly higher in those who were using a ventilator (OR=26.31; 95% CI=5.13${\sim}$142.86; P=.000), three or more kinds of antibiotics during admission (OR=58.82; 95% CI=16.13${\sim}$200; P=.000), or high APACHE II score (OR=1.16; 95% CI=1.08${\sim}$ 1.24; P=.000). Conclusion: The results of this study show that active surveillance culture can detect VRE colonization on admission to ICU and those who have acquired VRE in ICU. The analyzed VRE colonization and risk factors of VRE acquisition are expected to be useful in establishing guidelines for preventing VRE infection in ICU.

• 대한인간공학회지
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• 제23권3호
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• pp.121-134
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• 2004

A research project was conducted to study work-related musculoskeletal disorders （MSDs） at subway train repair plant in Korea. The project was consisted of 4 main parts; education on the topics of MSDs for all workers, symptom survey, medical check-up, investigation of MSD risk factors. The result of symptom survey showed that 95.2％ of the respondents complained pains on at least one part of the body. After cross-sectional analysis of various information and risk factors, 86.8％ of respondents were considered as active health surveillance level 1 that require continuous monitoring on their symptoms and working conditions. And 57.1％ of the respondents were considered as active health surveillance level 2 that needed medical check-ups for proper medical treatment. The analysis of occupational risk factors revealed that handling of heavy object (46.15％) and repeated awkward postures (46.15％) were two most contributing risk factors for the on-set of MSD at this work site followed by static strain (7.7％), and vibration and impact (3.8％). Medical examination was performed by an industrial medicine MD on 156 workers those considered as active health surveillance level 2. The result showed that 35 workers (20.7％) were considered as MSD patient group at severe level, and 68.6 workers (68.6％) were considered as moderate group and 18 workers (10.6％) were considered minor or normal group those have no symptom.

• 한국융합학회논문지
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• 제11권3호
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• pp.77-83
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• 2020

최근 지능형 예측감시 시스템이 등장하고 있다. 지능형 예측감시 시스템의 추론을 위해서는 현재 및 과거의 데이터가 필요하며, 이러한 데이터의 분석을 통하여 곧 발생할 상황에 대한 예측을 가능하게 한다. 그러나, 이러한 과정에서 영상 객체의 개인정보를 취급하게 될 소지가 높으므로, 개인정보보호를 위해서는 보안에 대한 고려가 필수적이다. 특히, 개인의 생활패턴, 주요 이동 경로 등에 대한 정보가 해킹을 통하여 공개적으로 노출된다면 프라이버시 측면에서 문제가 될 것이다. 기존의 영상감시 프레임워크는 개인정보보호 측면에서 한계점이 있으며, 특히 개인정보보호에 취약한 측면이 있다. 본 논문에서는 개인정보보호를 고려한 지능형 예측감시 시스템을 위한 보안 프레임워크를 제안하였다. 제안한 방법에서는 단말, 전송, 감시, 모니터링 계층으로 구분하여 단위별 세부 구성요소를 명시하였으며, 특히 객체 단위별 세부 접근제어와 비식별화를 지원하여 영상감시 과정에서의 능동형 개인정보보호가 가능하다. 또한, 데이터 전송시 보안 기능과 RBAC 제공을 통한 접근제어의 장점을 갖는다.

• Journal of Veterinary Science
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• 제22권2호
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• pp.26.1-26.6
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• 2021

Fourteen African swine fever (ASF) outbreaks occurred in the pig farms in the northwestern region of South Korea, near the border with North Korea, from September 16, 2019 to October 9, 2019. Active and passive surveillance on the ASF-infected farms indicated that the infection was limited only to pigsties where the infected pigs were detected on the farm for the first time before further transmission to other pigsties and farms. This early detection could be one of the pivotal factors for the prompt eradication of ASF in domestic pig farms within 1 month in the northwestern region of South Korea.

• Journal of Preventive Medicine and Public Health
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• 제41권4호
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• pp.219-224
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• 2008

Due to heightened concerns regarding possible bioterrorist attacks, the Korea Center for Disease Control and Prevention introduced syndromic surveillance systems, which have been run by emergency departments in hospitals throughout Korea since 2002. These systems are designed to identify illness clusters before diagnoses are confirmed and reported to public health agencies, to mobilize a rapid response, and thereby to reduce morbidity and mortality. The Korea Center for Disease Control and Prevention performed drop-in syndromic surveillance successfully during the World Cup Football Games in 2002, the Universiad games in 2004, and the Asian Pacific Economic Cooperation meeting in 2005. In addition, sustainable syndromic surveillance system involving the collaborative efforts of 125 sentinel hospitals has been in operation nationwide since 2002. Because active data collection can bias decisions a physician makes, there is a need to generate an automatic and passive data collection system. Therefore, the Korea Center for Disease Control and Prevention plans to establish computerized automatic data collection systems in the near future. These systems will be used not only fur the early detection of bioterrorism but also for more effective public health responses to disease.

• Korean Journal of Radiology
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• 제22권4호
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• pp.559-567
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• 2021

Objective: To evaluate the impact of multiparametric magnetic resonance imaging (mpMRI) before confirmatory prostate biopsy in patients under active surveillance (AS). Materials and Methods: This retrospective study included 170 patients with Gleason grade 6 prostate cancer initially enrolled in an AS program between 2011 and 2019. Prostate mpMRI was performed using a 1.5 tesla (T) magnetic resonance imaging system with a 16-channel phased-array body coil. The protocol included T1-weighted, T2-weighted, diffusion-weighted, and dynamic contrast-enhanced imaging sequences. Uroradiology reports generated by a specialist were based on prostate imaging-reporting and data system (PI-RADS) version 2. Univariate and multivariate analyses were performed based on regression models. Results: The reclassification rate at confirmatory biopsy was higher in patients with suspicious lesions on mpMRI (PI-RADS score ≥ 3) (n = 47) than in patients with non-suspicious mpMRIs (n = 61) and who did not undergo mpMRIs (n = 62) (66%, 26.2%, and 24.2%, respectively; p < 0.001). On multivariate analysis, presence of a suspicious mpMRI finding (PI-RADS score ≥ 3) was associated (adjusted odds ratio: 4.72) with the risk of reclassification at confirmatory biopsy after adjusting for the main variables (age, prostate-specific antigen density, number of positive cores, number of previous biopsies, and clinical stage). Presence of a suspicious mpMRI finding (adjusted hazard ratio: 2.62) was also associated with the risk of progression to active treatment during the follow-up. Conclusion: Inclusion of mpMRI before the confirmatory biopsy is useful to stratify the risk of reclassification during the biopsy as well as to evaluate the risk of progression to active treatment during follow-up.

• 한국임상수의학회지
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• 제30권4호
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• pp.258-263
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• 2013

The primary goal of this study was to compute sample sizes required to achieve the each aim of a variety of foot-and-mouth disease (FMD) surveillance programs, using a statistically valid technique that takes the following factors into account: sensitivity (Se) and specificity (Sp) of diagnostic test system, desired minimum detectable prevalence, precision, population size, and desired power of the survey. In addition, sample sizes to detect FMD if the disease is present and also as proof of freedom were computed. The current FMD active surveillance programs consist of clinical, virological, and serological surveillance. For the 2012 serological surveillance, annual sample sizes (n = 265,065) are planned at four separate levels: statistical (n = 60,884) and targeted (n = 115,232) at breeding pig farms and slaughter house, in together with the detection of structural proteins (SP) antibodies against FMD (n = 88,949). Overall, the sample size was not designed taking the specific aims of each surveillance stream into account. The sample sizes for statistical surveillance, assuming stratified two-stage sampling technique, was based to detect at least one FMD-infected case in the general population. The resulting sample size can be used to obtain evidence of freedom from FMD infection, not for detecting animals that have antibodies against FMD virus non-structural proteins (NSP). Additionally, sample sizes for targeted surveillance were not aimed for the population at risk, and also without consideration of statistical point of view. To at least the author's knowledge, sampling plan for targeted, breeding pig farms and slaughter house is not necessary and need to be included in the part of statistical surveillance. Assuming design prevalence of 10% in an infinite population, a total of 29 animals are required to detect at least one positive with probability of 95%, using perfect diagnostic test system (Se = Sp = 100%). A total of 57,211 animals needed to be sampled to give 95% confidence of estimating SP prevalence of 80% at the individual animal-level with a precision of ${\pm}5%$, assuming 800 herds with an average 200 heads per farm, within-farm variance of 0.2, between-farm variance of 0.05, cost ratio of 100:1 of farm against animals. Furthermore, 779,736 animals were required to demonstrate FMD freedom, and the sample size can further be reduced depending on the parameters assumed.

• 한국전자통신학회논문지
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• 제9권10호
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• pp.1095-1102
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• 2014

본 논문에서는 실시간 감시 시스템에서 인간의 활동성을 분석하기 위하여 움직임 벡터를 사용하며, 고속연산에 GPU를 활용한다. 먼저 가장 중요한 부분인 전경으로부터 적응적 가우시안 혼합기법, 두드러진 움직임을 위한 가중치 차영상 기법, 움직임 벡터를 이용하여 인간이라고 판단되는 블랍을 검출하고, 추출된 움직임 벡터를 이용하여 사람의 활동성을 분석한다. 본 논문에서는 사람의 행동을 크게 {Active, Inactive}, {Position Moving, Fixed Moving}, {Walking, Running}의 세 가지 메타 클래스로 분류하고 인식하였다. 실험을 위해서 약 300개의 상황을 연출하였으며, 약 86%~98% 의 인식률을 보였다. 또한 $1920{\times}1080$ 크기 영상에서 CPU 기반은 4.2초 정도 걸렸는데, GPU 기반에서는 0.4초 이내로 빨라진 결과를 얻었다.