• Bulletin of the Korean Chemical Society
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• v.28 no.2
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• pp.200-206
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• 2007

Pharmacophore models for lymphocyte-specific protein tyrosine kinase (P56 LCK) were developed using CATALYST HypoGen with a training set comprising of 25 different P56 LCK inhibitors. The best quantitative pharmacophore hypothesis comprises of one hydrogen bond acceptor, one hydrogen bond donor, one hydrophobic aliphatic and one ring aromatic features with correlation coefficient of 0.941, root mean square deviation (RMSD) of 0.933 and cost difference (null cost-total cost) of 66.23. The pharmacophore model was validated by two methods and the validated model was further used to search databases for new compounds with good estimated LCK inhibitory activity. These compounds were evaluated for their binding properties at the active site by molecular docking studies using GOLD software. The compounds with good estimated activity and docking scores were evaluated for physiological properties based on Lipinski's rules. Finally 68 compounds satisfied all the properties required to be a successful inhibitor candidate.

• Proceedings of the Korea Society for Simulation Conference
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• 2003.06a
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• pp.91-100
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• 2003

In this paper we investigate the role that warfare played In the formation of the network of alliances between sites that are associated with the formation of the state in the Valley of Oaxaca, Mexico. A model of state formation proposed by Marcos and Flannery (1996) is used as the basis for an agent-based simulation model. Agents reside in sites and their actions are constrained by knowledge extracted from the Oaxaca Surface Archaeological Survey (Kowalewski 1989). The simulation is run with two different sets of constraint rules for the agents. The first set is based upon the raw data collected in the surface survey. This represents a total of 79 sites and constitutes a minimal level of warfare (raiding) in the Valley. The other site represents the generalization of these constraints to sites with similar locational characteristics. This set corresponds to 987 sites and represents a much more active role for warfare in the Valley. The rules were produced by a data mining technique, Decision Trees, guided by Genetic Algorithms. Simulations were run using the two different rule sets and compared with each other and the archaeological data for the Valley. The results strongly suggest that warfare was a necessary process in the aggregations of resources needed to support the emergence of the state in the Valley.

• Structural Engineering and Mechanics
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• v.87 no.3
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• pp.231-242
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• 2023

A novel combinatorial type-2 adaptive neuro-fuzzy inference system (T2-ANFIS) and robust proportional integral derivative (PID) control framework for intelligent vibration mitigation of uncertain structural system is introduced. The fuzzy logic controllers (FLCs), are designed independently of the mathematical model of the system. The type-1 FLCs, have a limited ability to reduce the effect of uncertainty, due to their fuzzy sets with a crisp degree of membership. In real applications, the consequent part of the fuzzy rules is uncertain. The type-2 FLCs, are robust to the fuzzy rules and the process parameters due to the fuzzy degree of membership functions and footprint of uncertainty (FOU). The adaptivity of the proposed method is provided with the optimum tuning of the parameters using the neural network training algorithms. In our approach, the PID control force is obtained using the generalized type-2 neuro-fuzzy in such a way that the stability and robustness of the controller are guaranteed. The robust performance and stability of the presented framework are demonstrated in a numerical study for an eleven-story seismically-excited building structure combined with an active tuned mass damper (ATMD). The results indicate that the introduced type-2 neuro-fuzzy PID control scheme is effective to attenuate plant states in the presence of the structured and unstructured uncertainties, compared to the conventional, type-1 FLC, type-2 FLC, and type-1 neuro-fuzzy PID controllers.

• Journal of the Korean Society of School Health
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• v.19 no.2
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• pp.105-115
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• 2006

Purpose：This thesis was performed to evaluate the effect of the experience safety education on the safety behavior and standard of habit to the middle school students of one islands. Methods：The participants of this study included 43, located in the adjoining region in S county. While one of the class, composed of 19 students was designated as an experimental group, and the other class, composed of 24 students, was compared as a control group. Used program in this study was safety education program, 'Safe School, Safe Life' which was developed by Korea Occupational Safety & Health Agency. This program has emphasis on the virtual case rather than lecture style education. Results：The findings in this research were as follows. Indoor safety behavior was significant difference between the two groups. On the other hand, the effect on outdoor safety behavior was not difference. In playground case, active strength was needed without continuous attention. The effect of the experience safety behavior education was not shown in the area of traffic rules, pedestrian safety, and vehicle safety. But home safety behavior was effective. Education program on the manners of standard life habit gives positive results. But in the area of rules, this program was not effective, since students had tendency to emphasize the rigid scale rather than manners. Conclusion：These findings in the study give us the necessity of experience safety education program to prepare various situations of everyday life and to reinforce safety behavior and improve standard life habit.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.1
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• pp.1-13
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• 2012

AESA radar is able to instantaneously and adaptively position and control the beam, and such adaptive beam pointing of AESA radar enables to remarkably improve the multi-mission capability, compared with mechanically scanned array radar. AESA radar brings a new challenges, radar resource management(RRM), which is a technique efficiently allocating finite resources, such as energy and time to each task in an optimal and intelligent way. Especially radar beam scheduling is the most critical component for the success of RRM. In this paper, we proposed the several dispatching rules for radar beam scheduling, and compared the performance on the multi-function radar scenario. We also showed that the dispatching rule which differently applying SPF(Shortest Processing time First) and ERF(Earliest Request time First) according to beam processing latency is the most efficient.

• Lingua Humanitatis
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• v.1 no.2
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• pp.123-139
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• 2001

In the history of linguistics in the world the scholars in India could be regarded as the representative linguists, who had provided the cornerstone of the academic development at linguistics. Without looking into the contents of Indian linguistic theories devised and developed in the past it would be almost impossible to account for the origin of descriptive linguistics and historical linguistics. These linguistics trends became full-fledged in 19 and 20 century and are still accepted by a lot of researchers in order to analyze newly revealed languages and train students only coming up the toddling level of linguistic studies. In this paper I will show how far the influence of Indian linguistics has colored the flow of linguistic growth historically. Especially through the analysis of Panini grammar I will prove the intimate relationship between the Indian linguistic theory and the generative grammar - it is the most active theory at present. The methods that Panini applied to constitute the rules like sutra include lots of information, that also could be discovered at the rules postulated in the generative grammar. One of the common features found at both linguistic theories is the simplicity of rule representation. At the generative grammar a rule has to be established without any redundancy. When certain number of sounds like p, b, m show the same phonological. change relevant to lips (labial in linguistic term) different rules need not to be given for each sound separately. It is better to find a way of putting the sounds together in a rule with grouping the 3 sounds with the shared phonetic feature 'labial'. In Panini grammar the form of a rule was decided based on the simplicity, too. For example, sutra 6.1.77 shows the phonological connection between the vowels i, u r 1 and the semi-vowels y, v, r, 1. However, it does not require to postulate 4 individual rules respectively. Instead a rule in which the vowels and the semi-vowels are involved is suggested, and linguistically the rule make it clear that the more simpler the rules will be the better they can reflect the efficiency of human language acquisition. Although the systems introduced at Panini grammar have some sense of distance from the language education itself we cannot deny the fact that the grammar formulates the a turning point of linguistic development. It is essential for us to think over the grammar from the view point of the modem linguistic theories to understand their root and trunk more thoroughly. It will also help us to predict in which way linguistic tendency will proceed to in future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.7
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• pp.16-23
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• 2018

Chaos is one of the most significant topics in nonlinear science, and has been intensively studied since the Lorenz system was introduced. One characteristic of a chaotic system is that the signals produced by it do not synchronize with any other system. It therefore seems impossible for two chaotic systems to synchronize with each other, but if the two systems exchange information in just the right way, they can synchronize. This paper addresses the problem of synchronization in a modified Lorenz chaotic system based on active control, sliding mode control, and the Lyapunov stability theory. The considered synchronization scheme consists of identical drive and response generalized systems coupled with linear state error variables. For this, a brief overview of the modified Lorenz chaotic system is given. Then, control rules are derived for chaos synchronization via active control and slide mode control theory, with a strategy for solving the chattering problem. The asymptotic stability of the overall feedback system is established using the Lyapunov stability theory. A set of computer simulation works is presented graphically to confirm the validity of the proposed method.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.7C
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• pp.971-984
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• 2004

In the coming age of information warfare, information security patterns need to be changed such as to the active approach using offensive security mechanisms rather than traditional passive approach just protecting the intrusions. In an active security environment, it is essential that, when detecting an intrusion, the immediate confrontation such as analysing the intrusion situation in realtime, protecting information from the attacks, and even tracing the intruder. This paper presents an active intrusion-confronting system using a fake session and a honeypot. Through the fake session, the attacks like Dos(Denial of Service) and port scan can be intercepted. By monitoring honeypot system, in which the intruders are migrated from the protected system and an intrusion rule manager is being activated, new intrusion rules are created and activated for confronting the next intrusions.

• Journal of Digital Contents Society
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• v.13 no.1
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• pp.21-29
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• 2012

In ubiquitous computing environment, rising large scale data exchange through sensor network with sharply growing the internet, the processing of the continuous stream data is required. Therefore there are some mining researches related to the extracting of frequent structures and the efficient query processing of XML stream data. In this paper, we propose a mining method to extract frequent structures of XML stream data in recent window based on the active window sliding using trigger rule. The proposed method is a basic research to control the stream data flow for data mining and continuous query by trigger rules.

• The Transactions of the Korean Institute of Power Electronics
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• v.2 no.4
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• pp.45-55
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• 1997

According to the increase of factory-automation in the field of production, the importance of autonomous guided vehicle's(AGV) role is also increased. The study about an active and effective controller which can flexibly prepare for the changeable circumstance is in progressed. For this study, the research about action base system to evolve by itself is also being actively considered. In this paper, we composed an active and effective AGV fuzzy controller to be able to do self-organization. For composing it, we tuned suboptimally membership function using genetic algorithm(GA) and improved the control efficiency by the self-correction and generating the control rules. Self-organizing controlled(S0C) fuzzy controller proposed in the paper is capable of self-organizing by using the characteristics of fuzzy controller and genetic algorithm. It intuitionally controls AGV and easily adapts to the circumstance.