• Title/Summary/Keyword: Activation product

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Effects of Information Processing Types and Product Ownership on Usage Intention

  • CHOI, Nak-Hwan
    • The Journal of Industrial Distribution & Business
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    • v.12 no.5
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    • pp.47-58
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    • 2021
  • Purpose - Current research aimed at exploring the effect differences between the two types of processing product information such as the imagining and the considering on psychological product ownership which could influence the intent to purchase or use the product, and focused on identifying the interaction effects of activated memory information type and advertising information type on each of the information processing types. Research design, data, and methodology - This study divided the information processing types into imagining and considering, and the consumer's memories were divided into autobiographical or episodic and semantic memory. The advertising information was approached in each of event information being together with the product and product feature information. At empirical study, 2(two types of memory activation: episodic and semantic memory activation) ∗ 2(two types of advertising information: event-focused and product feature-focused advertising information) between-subjects design was used to make four types of questionnaire according to the type of experimental groups. Through the survey platform, 'questionnaire stars' of 'WeChat' in China, 219 questionnaire data were collected for empirical study. The structural equation model in AMOS 26 and Anova were used to verify hypotheses. Results - First, the ownership affected the usage intent positively. Second, the imagining did not affect the psychological ownership but did directly affect the usage intention, and the considering affected the ownership positively. Third, the episodic memory activation positively influenced the imagining and negatively affected the considering, whereas the semantic memory activation positively influenced the considering and negatively affected the imagining. Fourth, event-advertising information increased the effects of the activated episodic memory on the imagining, and feature-advertising information increased the effects of the activated semantic memory on the considering. Conclusions - marketers should develop and advertise their product-related event message to trigger the imaging that directly increase the intent to purchase or use their product, when consumers are under the activation of their episodic memory. And marketers should advertise their product feature-related message to trigger the considering that could induce consumers' ownership for their product to increase the intent to purchase or use their product, when they are under the activation of their semantic memory.

Neuroprotective mechanism of corydaline in glutamate-induced neurotoxicity in HT22 cells

  • Baskar Selvaraj;Dae Won Kim;Ki-Yeon Yoo;Keunwan Park;Thi Thu Thuy Tran;Jae Wook Lee;Heesu Lee
    • International Journal of Oral Biology
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    • v.49 no.1
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    • pp.10-17
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    • 2024
  • Glutamate-mediated oxidative stress causes neuronal cell death by increasing intracellular Ca2+ uptake, reactive oxidative species (ROS) generation, mitogen-activated protein kinase (MAPK) activation, and translocation of apoptosis-inducing factor (AIF) to the nucleus. In the current study, we demonstrated that corydaline exerts potent neuroprotective effects against glutamate-induced neurotoxicity. Treatment with 5 mmol/L glutamate increased cellular Ca2+ influx, ROS generation, MAPK activation, and AIF translocation. In contrast, corydaline treatment decreased cellular Ca2+ influx and ROS generation. Western blot analysis revealed that glutamate-mediated MAPK activation was attenuated by corydaline treatment. We further demonstrated that corydaline treatment inhibited the glutamate-mediated translocation of AIF to the nucleus. We propose that corydaline is a promising lead structure for the development of safe and effective neuroprotectants.

Streptochlorin, a Marine Natural Product, Inhibits $NF-{\kappa}B$ Activation and Suppresses Angiogenesis In Vitro

  • Choi, In-Kwon;Shin, Hee-Jae;Lee, Hyi-Seung;Kwon, Ho-Jeong
    • Journal of Microbiology and Biotechnology
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    • v.17 no.8
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    • pp.1338-1343
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    • 2007
  • Angiogenesis is an essential step in tumor progress and metastasis. Accordingly, small molecules that inhibit angiogenesis would appear to be a promising way to cure angiogenesis-related diseases, including cancer. In the present study, we report that streptochlorin, a small molecule from marine actinomycete, exhibits a potent antiangiogenic activity. The compound potently inhibited endothelial cell invasion and tube formation stimulated with vascular endothelial cell growth factor (VEGF) at low micromolar concentrations where it showed no cytotoxicity to the cells. In addition, streptochlorin inhibited TNF-${\alpha}$-induced $NF-{\kappa}B$ activation in the newly developed cell-based reporter gene assay. These data demonstrate that streptochlorin is a new inhibitor of $NF-{\kappa}B$ activation and can be a basis for the development of novel anti-angiogenic agents.

Improving the Reactivity and Harmlessness of Recalcitrant Contaminants by Reduction-oxidation-linked Process (환원-산화 연계처리를 통한 니트로벤젠의 반응성 향상 및 무해화 연구)

  • Kwon, Hee-Won;Hwang, Inseong;Kim, Young-Hun
    • Journal of Environmental Science International
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    • v.29 no.12
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    • pp.1205-1211
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    • 2020
  • In this study, the applicability of reduction-oxidation-linked treatment was evaluated for nitrobenzene and a by-product by analyzing the reaction kinetics. Nitrobenzene showed very low reactivity to persulfate that was activated using various methods. Nitrobenzene effectively reacted through the reduction process using Zero-Valent Iron (ZVI). However, aniline, a toxic substance, was produced as a by-product. Reduction-oxidation-linked treatment is a method that can allow the oxidative degradation of aniline after reducing nitrobenzene to aniline. The experimental results show improved reactivity and complete decomposition of the by-product. Improved reactivity and decomposition of the by-product were observed even under conditions in which the reduction-oxidation reaction was induced simultaneously. No activator was injected for persulfate activation in the process of reducing oxidant linkage, and the activation reaction was induced by ferrous iron eluted from the ZVI. This indicates that this method can be implemented relatively simply.

A study on the Activation Plan Using public purchase system of the Disability Firm manufactured product (장애인기업 생산제품의 공공구매제도를 통한 활성화 방안에 관한 연구)

  • Song, Soo-Jeong;Won, Joon-Ho
    • Journal of the Korea Safety Management & Science
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    • v.12 no.3
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    • pp.145-151
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    • 2010
  • The research which sees the disability firm led and public procurement market penetration the base will be able to grow prepared and with the petal of the disability firm for a support disability firm manufactured product public purchase activation plan of the government offices groped. disability firm manufactured products purchase promotion plan and policy of the government offices presents the fact that with the aim.

A Study on Radioactive Source-term Assessment Method for Decommissioning PWR Primary System (PWR 1차계통내 해체 방사성선원항 평가방법에 관한 연구)

  • Song, Jong Soon;Kim, Hyun-Min;Lee, Sang-Heon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.12 no.2
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    • pp.153-164
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    • 2014
  • Currently, there are many programs which are now being developed or already developed to predict radionuclide and corrosion product at the stage of designing NPP. However, since there are not many developments in evaluating quantity of activation corrosion products occurring when disassembling a nuclear power plant there exist some difficulties in calculating accurately. In order to evaluate activation products inventory for the research of effect of neutron activation in the reactor vessel, component of nuclear reactor and adjacent structures, it should be evaluated by using operation history of nuclear reactor, material composition of structure and average neutron flux in every field representing fixed structure of nuclear reactor. In this study, CORA, PACTOLE, CRUDSIM, CREAT and ACE codes are analyzed to predict the quantity of radionuclide and corrosion product of primary reactor which is used at the stage of designing. As a future study, the accuracy in calculating the quantity of product corrosion can be increase by finding out the possibility of use and improvement for evaluation of the decontamination.

Nano-particles of Mechanochemical Synthesis

  • Urakaev, Farit Kh.
    • Journal of the Speleological Society of Korea
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    • no.71
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    • pp.5-11
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    • 2006
  • A theoretical investigation of the solid phase mechanochemical synthesis of nano sized target product on the basis of dilution of the initial powdered reagent mixture by another product of an exchange reaction is presented. On the basis of the proposed 3 mode particle size distribution in mechanically activated mixture, optimal molar ratios of the components in mixture are calculated, providing the occurrence of impact friction contacts of reagent particles and excluding aggregation of the nanosized particles of the target reaction product. Derivation of kinetic equations for mechanochemical synthesis of nanoscale particles by the final product dilution method in the systems of exchange reactions is submitted. On the basis of obtained equations the necessary times of mechanical activation for complete course of mechanochemical reactions are designed. Kinetics of solid phase mechanosynthesis of nano TlCl by dilution of initial (2NaCl+$Tl_2SO_4$) mixture with the exchange reaction product (diluent,$zNa_2SO_4$, z=z*=11.25) was studied experimentally. Some peculiar features of the reaction mechanism were found. Parameters of the kinetic curve of nano TlCl obtained experimentally were compared with those for the model reaction KBr+TlCl+zKCl=(z+1) KCl+TlBr (z=z1*=13.5), and for the first time the value of mass transfer coefficient in a mechanochemical reactor with mobile milling balls was evaluated. Dynamics of the size change was followed for nanoparticle reaction product as a function of mechanical activation time.

Calculation of The Core Damage & FP Release Behavior for The PHEBUS FPT0 Similar to Cold Leg Break Accident Using MELCOR

  • Park, Jong-Hwa;Cho, Song-Won;Kim, Hee-Dong
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05b
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    • pp.637-642
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    • 1996
  • This paper presents the analysis results for the core degradation processes and the fission product release of the PHEBUS FPT0 experiment using MELCOR1.8.3. The objective of this study is to assess models associated with the core damage and fission product behavior in MELCOR. The calculation results were much improved through sensitivity studies. Thermal/hydraulic behavior in the core and the circuit was well predicted under the intact core geometry. In non-eutectic model case. the UO$_2$ dissolution model in the MELCOR always showed such a tendency that the resulting dissolved UO$_2$ mass was small at the highly oxidized condition due to the model logic. Total H$_2$ generation mass was underpredicted because the stiffner was not modeled and the liner in the shroud was not allowed to be oxidized in MELCOR. Some difficulties were found in modeling the activation product were solved by manipulating the RN input associated with the initial fission product inventory. These problem were occurred because there are no control rod model in MELCOR. Generally the fission product release ratio showed a similar trend compared with the measured data except the activation product. which have no model to simulate in MELCOR.

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Theory of Nanoparticles Mechanosynthesis

  • Urakaev, Farit Kh.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.07a
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    • pp.405-406
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    • 2005
  • A theoretical investigation of the solid-phase mechanochemical synthesis of nano-sized target product on the basis of dilution of the initial powdered reagent mixture by another product of an exchange reaction is presented. On the basis of the proposed 3-mode particle size distribution in mechanically activated mixture, optimal molar ratios of the components in mixture are calculated, providing the occurrence of impact-friction contacts of reagent particles and excluding aggregation of the nanosized particles of the target reaction product. Derivation of kinetic equations for mechanochemical synthesis of nanoscale particles by the final product dilution method in the systems of exchange reactions is submitted. On the basis of obtained equations the necessary times of mechanical activation for complete course of mechanochemical reactions are designed. Kinetics of solid phase mechanosynthesis of nano-TlCl by dilution of initial (2NaCl + $Tl_2SO_4$) mixture with the exchange reaction product (diluent, $zNa_2SO_4$, $z=z^*=11.25$) was studied experimentally. Some peculiar features of the reaction mechanism were found. Parameters of the kinetic curve of nano-TlCl obtained experimentally were compared with those for the model reaction KBr + TlCl + zKCl = (z + 1) KCl + TlBr ($z=z_l^*=13.5$), and for the first time the value of mass transfer coefficient in a mechanochemical reactor with mobile milling balls was evaluated. Dynamics of the size change was followed for nanoparticle reaction product as a function of mechanical activation time.

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The Usage Patterns of MCSs, and the Activation of Knowledge Management Processes for Corporate Innovations : Innovation Openness (경영통제시스템의 이용 행태에 따른 지식경영 과정들의 활성화와 제조기업 혁신 : 혁신의 공개성)

  • Choe, Jong-Min;Bae, Seong-Ho
    • Korean Management Science Review
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    • v.34 no.3
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    • pp.43-60
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    • 2017
  • This study empirically examined the differences in degrees of product or process innovations according to the activation forms of all knowledge management (KM) processes (i.e., socialization, internalization, externalization, and combination), which are influenced by the usage patterns of management control systems (MCS)(i.e., interactive and diagnostic usage patterns). We empirically investigated and identified the links among usage patterns of MCS, the activation forms of KM processes, and the kinds of innovation promoted. Under high competitive conditions, it was found that the interactive usage of MCS is relatively more preferred and enhanced. However, when environmental uncertainty is high, it was shown that the diagnostic use of MCS is more emphasized. Thus, it is evident that the use patterns of MCS are determined by environmental conditions. From the results of this study, it was suggested that under high interactive use of MCS, the activation of socialization and internalization is more enhanced than the facilitation of externalization. It was also observed that when both interactive and diagnostic usage of MCS are high, KM processes are more activated and strengthened. The results indicated that under high activation of KM processes, product innovation as well as process innovation are more frequently occurred. Finally, the results of this study suggested that according to the levels of innovation openness, major innovations are more frequently occurred and promoted than minor innovations.