• Journal of Digital Convergence
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• v.20 no.1
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• pp.249-255
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• 2022

The purpose of this study is to establish and propose a post-diagnosis checklist for the revitalization of domestic regional co-brands that have not been activated despite many strengths. First, I looked into the brand revitalization methodology through prior researches and among them, referring to the cause-remedies model, the cause of the deactivation of the co-brand and the currently used revitalization method were examined through case studies and expert interviews. Regarding the currently used method, the reason for using the method was inferred, and the factors corresponding to the cause and effect were found and categorized in the inferred sentence, and the corresponding detailed items were set and the checklist items were presented. Although this study has a limitation in that there is no practical checklist verification, it is expected that a specific activation plan will be presented through verification of future studies.

• Parasites, Hosts and Diseases
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• v.51 no.4
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• pp.393-400
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• 2013

Ocular toxoplasmosis is a disease caused by the infection with Toxoplasma gondii through congenital or acquired routes. Once the parasite reaches the retina, it proliferates within host cells followed by rupture of the host cells and invasion into neighboring cells to make primary lesions. Sometimes the restricted parasite by the host immunity in the first scar is activated to infect another lesion nearby the scar. Blurred vision is the main complaint of ocular toxoplasmic patients and can be diagnosed by detection of antibodies or parasite DNA. Ocular toxoplasmosis needs therapy with several combinations of drugs to eliminate the parasite and accompanying inflammation; if not treated it sometimes leads to loss of vision. We describe here clinical features and currently available chemotherapy of ocular toxoplasmosis.

• Clinical and Experimental Pediatrics
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• v.59 no.3
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• pp.105-113
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• 2016

Diffuse alveolar hemorrhage (DAH) is a life-threatening pulmonary complication in patients with hematologic malignancies or autoimmune disorders. The current treatment options, which include corticosteroids, transfusions, extracorporeal membrane oxygenation (ECMO), and immunosuppressants, have been limited and largely unsuccessful. Recombinant activated factor VII (rFVIIa) has been successfully administered, either systemically or bronchoscopically, to adults for the treatment of DAH, but there are few data on its use in pediatric patients. The current literature in the PubMed database was reviewed to evaluate the efficacy and risk of rFVIIa treatment for DAH in pediatric patients. This review discusses the diagnosis and treatment of DAH, as well as a new treatment paradigm that includes rFVIIa. Additionally, the risks and benefits of off-label use of rFVIIa in pediatric patients are discussed.

• Journal of Microbiology and Biotechnology
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• v.16 no.7
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• pp.1149-1153
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• 2006

In this study, nuclease-resistant RNA aptamers that are specific for Jurkat T leukemia cells were selected by a subtractive systemic evolution of ligands by exponential enrichment (SELEX) method. A randomized nuclease-resistant RNA library was incubated with normal peripheral blood mononuclear cells (PBMC) in each round to preclude RNAs that recognize the common cellular components on the surface of normal and cancer cells. The precluded RNAs were used for the selection of Jurkat T cell-specific aptamers, and the specific RNAs were then gradually enriched from start to the following selections. After 16 rounds of the subtractive SELEX, the selected aptamers were found to preferentially bind to Jurkat T cells, but not to the normal PBMC, evidenced by fluorescence-activated cell sorting analysis. Thus, the subtractive SELEX can be used to identify ligands to cancer-specific biological markers without prior knowledge of the nature of markers. The aptamers could be applied to specific cell sorting, tumor therapy, and diagnosis, and moreover, to find cancer cell-specific markers.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7431-7434
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• 2015

As an important component of innate immune system, neutrophil has been involved in many other physiological processes, including tumor-related diseases. In 2004, the phenomenon of NETs was reported for the first time. Extracellular decondensed chromatin, released from activated neutrophils, forms a network structure, which is NETs. This review focuses on the function of NETs in tumor cell proliferation, metastasis, and tumor-associated thrombosis; it also explores the application of NETs specific markers in the diagnosis of pre-thrombotic state and tumor associated diseases; it also explores NETs inhibitor for the treatment of tumor-related diseases. In view of the rapid development of NETs, it may provide new therapeutic targets for tumor-associated thrombosis, and even tumor itself.

• Molecules and Cells
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• v.38 no.2
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• pp.95-104
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• 2015

The development of cancer has been an extensively researched topic over the past few decades. Although great strides have been made in cancer prevention, diagnosis, and treatment, there is still much to be learned about cancer's micro-environmental mechanisms that contribute to cancer formation and aggressiveness. Macrophages, lymphocytes which originate from monocytes, are involved in the inflammatory response and often dispersed to areas of infection to fight harmful antigens and mutated cells in tissues. Macrophages have a plethora of roles including tissue development and repair, immune system functions, and inflammation. We discuss various pathways by which macrophages get activated, various approaches that can regulate the function of macrophages, and how these approaches can be helpful in developing new cancer therapies.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.636-638
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• 2022

This paper is a study to apply CNN(Convolution Neural Network) to fundus images for identifying glaucoma. Fundus images are evaluated in the field of medical diagnosis detection, which are diagnosing of blood vessels and nerve tissues, retina damage, various cardiovascular diseases and dementia. For the experiment, using normal image set and glaucoma image set, two types of image set are classifed by using AlexNet. The result performs that glaucoma with abnormalities are activated and characterized in feature map.

• Journal of the Korea Society of Computer and Information
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• v.16 no.2
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• pp.141-151
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• 2011

This paper suggests the Facility Management System for plant factory promising to be a core technology of the agriculture in the future. This system makes diagnoses that status from sensors or facilities in the factory for exact operation and monitors the internal environment with the control status in real-time. It is expected that we could operate a plant factory safely and effectively by using the system. The system consists of the data management module, the context provider module, the context interpreter module, the service provider module, the data storage and user interface. The system provide with the failure diagnosis service, the facility control service, and the high-reliability monitoring service via the interactions between above modules. The failure diagnosis service determines whether the sensors or facility devices are in failure or not, and informs the administrator of their conditions. The facility control service is activated in case if the facilities need to be managed during the diagnosis for failure or malfunction processes. The high-reliability monitoring service provides the administrator with verified data through the failure diagnosis service. Then we confirmed that the suggested system operates correctly through the system simulation.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.332-346
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• 2013

Since the enactment of Social Enterprise Promotion Act in 2007, the December 2012 was now 801 organizations certified as social enterprise. Social enterprise in urban areas are much more activated, in order to social enterprises in rural areas be activated, what you need to improve and what measures will need to be applied by the practitioners and researchers is a challenge to be reflective. In this study, We searched for ways of social enterprise activation in rural areas, conducted by case study of social enterprise transition probabilities diagnosis and demand survey of local people based in Boseong. For research purposes, this study selects 41 corporate and non-profit organizations in order to examine social enterprise transition probabilities, the potential social enterprise certification, social enterprise-related demand, awareness of sustainability, and local issues.

• Journal of the Korean Society for Heat Treatment
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• v.23 no.3
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• pp.150-155
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• 2010

Generally, plasma nitriding process has composed with a nitriding layer within glow discharge region occurred by energy exchange. The dissociations of nitrogen molecules are very difficult to make neutral atoms or ionic nitrogen species via glow discharge area. However, the captured electrons in which a double-folded screen with same potential cathode can stimulate and come out some single atoms or activated ionic species. It was showed an important thing that is called "hat is a dominant component in this nitriding process?" in plasma nitriding process and it can take an effective species for without compound layer. During a plasma nitriding process, it was able to estimate with analyzing and identification by optical emission spectroscopy (OES) study. And then we can make comparative studies on the nitrogen transfer with plasma nitriding and ATONA process using plasma diagnosis and metallurgical observation. From these observations, we can understand role of active species of nitrogen, like N, $N^+$, ${N_2}^+$, ${N_2}^*$ and $NH_x$-radical, in bulk plasma of each process. And the same time, during DC plasma nitriding and other processes, the species of FeN atom or any ionic nitride species were not detected by OES analyzing.