• Title/Summary/Keyword: Action Equation 2.0

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The Effect of Social Capital on Creating Shared Value for Educational Companies

  • HONG, Seung-Hyun;KIM, Seong-Gon
    • The Journal of Industrial Distribution & Business
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    • v.13 no.2
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    • pp.33-43
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    • 2022
  • Purpose: To examine the strength of social capital (SC) that are likely to affect Created share value (CSV) factors. This research aims to conduct a literature review to establish the components of SC and CSV identified within educational research and use factor analysis to identify how numerical values differ from the average and the amount of variance expressed in eigenvalue and factor score. Research design, data and methodology: To achieve the purpose of the study and provide adequate empirical results, we conducted the structural equation analysis using IBM AMOS 24.0 and collect online questionnaires from top practitioners, managers and non-managerial employees in Korean education firms, which will be used to conduct a factor analysis to assess SC's effect on CSV. Results: Final analysis of the path coefficient of the research model indicated that the SC values based on six have a significantly positive (+) effect on CSV values based on three categories (β=.35, p<.001). Therefore, the current research accepts the hypothesis in determining that SC can enhance the impact of CSV in educational companies. Conclusions: From the study, the practitioners of education companies should make more efforts to find action plans to create corporate social responsibility and shared value, which are required throughout society.

Interaction Factors and Response Surface Analysis on the Factors Influencing the Flow Front Temperature at Metal Injection Mold (금속사출 유동선단온도에 영향을 미치는 주요 인자들의 상호관계 및 반응표면분석)

  • Kim, Myoung-Ho;Yoon, Hi-Seak
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.2
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    • pp.248-255
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    • 2013
  • The objective of this study is to optimize the Metal Injection Molding(MIM) process with design of experiments(DOE) and numerical analysis. To derive the optimal process condition, experiment or numerical analysis was performed under various process conditions. To analyze the interaction among influential factors contributing to the temperature at flow front and response surface in MIM, both central point and axial point were added to the full factorial design with 2 levels and 5 factors and then their impacts on response variable in 43 experimental conditions were analyzed and the significance was evaluated. As a result, sprue, runner, and gate were completely filled in about 0.247 seconds after injection, the front part of the green body was filled in about 0.3344 seconds, the green body except gate, etc changed to almost solid state in about 3.29 seconds, the Packinging pressure was completed in about 6.29 seconds, and the green body inside and outside and sprue, etc became solid in 13.2 seconds. The impact of individual or reciprocal action of factors on the temperature at flow front was analyzed through regular probability, test statistics, main effect, and interaction effect. As a result, of a total of 31 combinations of factors, 9 unit factors and reciprocal actions were significant, and the screening was also possible. A proper regression equation was drawn with regression analysis and response surface design on the response variable of temperature at flow front, and the applicability could be verified.

Characteristics and Action Pattern of Alkaline Protease from Streptomyces gviseus HC-1141 (Streptomyces griseus HC-1141이 생성하는 Alkaline Protease의 특성 및 작용양상)

  • Choi, Cheong;Chung, Yung-Gun;Sung, Sam-Kyung;Choi, Kwang-Soo;Lee, Jae-Sung;Cho, Young-Je;Chun, Sung-Sook
    • Microbiology and Biotechnology Letters
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    • v.20 no.3
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    • pp.295-301
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    • 1992
  • An alkaline protease producing microorganism was isolated from soil and identified as Streptomyces griseus HC-1141. The optimum pH and temperature for the purified enzyme activity were 8.0 and $60^{\circ}C$, respectively. The enzyme was relatively stable in the pH range of 7.0-9.0 and at the temperature below $60^{\circ}C$. The activity of purified enzyme was inhibited by $Hg^{2+}$, $Cu^{2+}$, $Zn^{2+}$, $Ba^{2+}$ and $Fe^{2+}$, whereas activated by $Mn^{2+}$ and $Ca^{2+}$. $\varepsilon$-Amino caproic acid, 2,4-dinitrophenol and iodine did not show inhibitory effect on the activity of alkaline protease, but p-chloromercuribenzoic acid, ethylendiaminetetraacetic acid showed inhibitory effect on the enzyme activity. These result suggested that the protease was metalloenzyme, and require a reactive SH group for the activity. The reaction of this enzyme follows typical Michaelis-Menten kinetics with the $K_m$ value of $2.229{\times}10^{-4}$M and the $V_{max}$ of $46.08 {\mu}$g/min for casein. The activation energy for the alkaline protease calculated by Arrhenius equation was 3.643 kcal/mol. This enzyme hydrolyzed casein more rapidly than the hemoglobin and egg albumin.

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Characteristics and Action Pattern of Polygalacturonase from Rhizopus oryzae CJ-2114 (Rhizopus oryzae CJ-2114가 생성하는 Polygalacturonase의 특성 및 작용양상)

  • Chung, Yung-Gun;Cho, Young-Je;Kwon, Oh-Jin;Choi, Cheong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.2
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    • pp.195-200
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    • 1992
  • Rhizopus oryzae CJ-2114 was selected for its strong polygalacturonase activity among various strains of mold found in soil. The optimum pH for the enzyme activity was 4.0 and optimum temperature was 4$0^{\circ}C$. The activation energy for the polygalacturonase was calculated by Arrhenius equation was 2.048㎉/㏖. The reaction of this enzyme followed typical Michaelis-Menten kinetics with the Km value of 54.05mM with the $V_{max}$ of 13.9m mole/min. The enzyme is relatively stable in acidic condition. The activity of polygalactur-onase was inhibited completely by C $u^{2+}$, P $b^{2+}$ and Z $n^{2+}$, $_Mn^{2+}$ at concentration of 1 mM. The enzyme can be inactivated by the treatment with maleic anhydride and iodine. The results indicate the possible involvement of histidine at active site. When polygalacturonase from Rhizopus oryzae CJ-2114 was reacted with poly-galacturonic acid as a substrate mono-, di-, and oligogalacturonic acid were produced at early and mono-, digalacturonic acid produced at late incubation time. time.

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Computational Drug Discovery Approach Based on Nuclear Factor-κB Pathway Dynamics

  • Nam, Ky-Youb;Oh, Won-Seok;Kim, Chul;Song, Mi-Young;Joung, Jong-Young;Kim, Sun-Young;Park, Jae-Seong;Gang, Sin-Moon;Cho, Young-Uk;No, Kyoung-Tai
    • Bulletin of the Korean Chemical Society
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    • v.32 no.12
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    • pp.4397-4402
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    • 2011
  • The NF-${\kappa}B$ system of transcription factors plays a crucial role in inflammatory diseases, making it an important drug target. We combined quantitative structure activity relationships for predicting the activity of new compounds and quantitative dynamic models for the NF-${\kappa}B$ network with intracellular concentration models. GFA-MLR QSAR analysis was employed to determine the optimal QSAR equation. To validate the predictability of the $IKK{\beta}$ QSAR model for an external set of inhibitors, a set of ordinary differential equations and mass action kinetics were used for modeling the NF-${\kappa}B$ dynamic system. The reaction parameters were obtained from previously reported research. In the IKKb QSAR model, good cross-validated $q^2$ (0.782) and conventional $r^2$ (0.808) values demonstrated the correlation between the descriptors and each of their activities and reliably predicted the $IKK{\beta}$ activities. Using a developed simulation model of the NF-${\kappa}B$ signaling pathway, we demonstrated differences in $I{\kappa}B$ mRNA expression between normal and different inhibitory states. When the inhibition efficiency increased, inhibitor 1 (PS-1145) led to long-term oscillations. The combined computational modeling and NF-${\kappa}B$ dynamic simulations can be used to understand the inhibition mechanisms and thereby result in the design of mechanism-based inhibitors.

EFFECT OF TEMPERATURE ON FLUORESCENCE QUENCHING BY STEADY STATE AND TRANSIENT METHODS IN SOME ORGANIC LIQUID SCINTILLATORS

  • Giraddi, T.P.;Kadadevarmath, J.S.;Chikkur, G.C.;Rath, M.C.;Mukherjee, T.
    • Journal of Photoscience
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    • v.4 no.3
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    • pp.97-103
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    • 1997
  • The effect of temperature on the fluorescence quenching of 2-(4-Methoxyphenyl)-5-(1-naphthyl)-1,3,4-oxadiazole (MPNO1), 2-(4-Methoxyphenyl)-5-(2-naphthyl)-1,3,4-oxadiazote(MPNO2), by aniline, and 2-Phenylindole (2-PI) by CCk, in toluene by steady state method and in benzene by time-resolved method have been carried out in the temperature range 30 - 70$\circ$C. The Stem-Volmer (S-V) plots, I$_0$/I against quencher concentration [Q] at different temperanares show positive deviations. The fluorescence lifetimes determined at different temperatures show no systematic variations and the variations being within the experimental error, the average values of lifetimes $ $\tau$ (t) are taken for further calculations. Rate constants such as Stem-Volmer quenching constants K$_sv}$, quenching rate parameters k$_q$ and k'$_q$, static quenching constant V and kinetic distance r are determined using the modified Stem-Volmer equation and sphere of action static quenching model. In order to see whether the reactions are diffusion limited, equations k$_q$ = e$^{-Eq/RT}$ and k'$_q$ = e$^{-Eq/RT}$ are used to determine the values of E$_q$ and E'$_q$, the activation energies for collisional quenching and the values of E$_q$ are 14.53. 17.28 and 16.20 kJ mole$^{-1}$ for MPNO1, MPNO2 and 2-PI respectively and the values of E'$_q$ are 14.62 and 17.73 for MPNO1 and MPNO2 respectively. From the magnitudes of various quantities it has been concluded that the reactions are diffusion limited and the observed positive deviations in the S-V plot are due to static and dynamic quenching.

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A Study on the Development of Reinforced Earth wall by Geotextile (토목섬유를 이용한 보강토옹벽의 개발)

  • 도덕현;유능환
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.28 no.2
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    • pp.63-73
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    • 1986
  • The model was developed by applying the principles of Bacot and Vidal to measure the behavior of deformation of the reinforced earth wall, and various tasts were performed by using the plastic fabric filter and the galvanized steel plate as a strip. The results obtained are as follows; 1. When the reinforced earth wall is deformed by the load, the strip is completely reinforced by the backfill materials and changed to the rigid block state, under the state of failure which permits sliding only, the next theoretical equation is formed. (H/L) . tan$\theta$ [cosO-sinOtanO] =2sinO[tan($\theta$ +0) +tanO] 2.The degree of the mutual reinforcement of the backfill material and the strip depend on the physical characteristics of the each material especially the angle of shearing resistance of the backfill material is desirable over 20$^{\circ}$ and, if it is over 400, its function could be a maximum. 3.The distribution of the maximum tensile strain of the reinforcement is changing with the height of reinforced earth wall, and when the height from bottom of the reinforced earth wall is 1.85 to 3. 35m, the maximum tensile strain appears at 2m from the skin element. The maximum tensile strain is increased by the depth of the reinforced earth wall from surface, and increased with the lapse of time after construction. 4.The failure surface of the reinforced earth wall by the concrete skin was about 60$^{\circ}$and the failure behavior of the reinforced earth wall in which the fabric filter was buried was slow, and so the pore pressure could be decreased. 5.It is possible to construct the fabric retained earth wall by the plastic fabric filter only. And the reinforcing effect between the steel plate and the plastic fabric filter is not largely different. however, in the aspect of the economic durability, the plastic fabric filter is more advantageous. 6.The reinforcing action mainly depends on the width and the length of the reinforcing materials, if possible, the full width is advantageous to enlarge the contact area with backfill. but considering the economic aspect, it is neccessary to develop the method controlling the space of the strip.

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Association between Scrub Typhus Outbreaks and Meteorological Factors in Jeollabuk-do Province (전북지역 쯔쯔가무시증 발생과 기후요소의 상호 관련성)

  • Kang, Gong-Unn;Ma, Chang-Jin;Oh, Gyung-Jae
    • Journal of Environmental Health Sciences
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    • v.42 no.1
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    • pp.41-52
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    • 2016
  • Objectives: Scrub typhus is one of the most prevalent vector-borne diseases. It is caused by Orientia tsutsugamushi, which is transmitted when people are bitten by infected chigger mites. This study aims at quantifying the association between the incidence of scrub typhus and meteorological factors in Jeollabuk-do Province over the period 2001-2015. Methods: Reported cases of scrub typhus were collected from the website of the Disease Web Statistical System supported by the Korea Centers for Disease Control and Prevention (KCDC). Simultaneous meteorological data, including temperature, rainfall, relative humidity, and sunshine duration were collected from the website of the National Climate Data Service System by the Korea Meteorological Administration. Correlation and regression analyses were applied to identify the association between the incidence of scrub typhus and meteorological factors. Results: The general epidemiological characteristics of scrub typhus in Jeollabuk-do Province were similar to those nationwide for sex, age, and geographical distribution. However, the annual incidence rate (i.e., cases per 100,000) of scrub typhus in Jeollabuk-do Province was approximately four times higher than all Korea's 0.9. The number of total cases was the highest proportion at 13.3% in Jeonbuk compared to other regions in Korea. The results of correlation analysis showed that there were significant correlations between annual cases of scrub typhus and monthly data for meteorological factors such as temperature and relative humidity in late spring and summer, especially in the case of temperature in May and June. The results of regression analysis showed that determining factors in the regression equation explaining the incidence of scrub typhus reached 46.2% and 43.5% in May and June. Using the regression equation, each 1oC rise in the monthly mean temperature in May or June may lead to an increase of 38 patients with scrub typhus compared to the annual mean of incidence cases in Jeollabuk-do Province. Conclusion: The result of our novel attempts provided rational evidence that meteorological factors are associated with the occurrence of scrub typhus in Jeollabuk-do. It should therefore be necessary to observe the trends and predict patterns of scrub typhus transmission in relation to global-scale climate change. Also, action is urgently needed in all areas, especially critical regions, toward taking steps to come up with preventive measures against scrub typhus transmission.

A Study on Synthesis of Organic Plant Surfactant and Its Solubilizing Action on Bergamot Oil (유기농 식물성 계면활성제의 합성과 베르가못오일에 대한 가용화력에 관한 연구)

  • Kim, In-Young;Noh, Ji-Min
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.4
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    • pp.1208-1218
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    • 2019
  • The study is on the cosmetic solubilizing power of organic plant surfactants. The blended high purity polyglyceryl-10 oleate and polyglyceryl-10 stearate mixtures were synthesized using organically certified raw materials to develop surfactants having excellent solubilizing power. The mixture is called "Solubil ORG-1300". The appearance of this material is a pale yellowish paste, with a specific odor. The specific gravity was 1.12 and it was high purity that acid value was 0.072±0.1. The HLB value of this natural surfactant was averaged = 15.1 and calculated through the Griffin equation. Mechanically it is explained how organic surfactant are available with fragrance and oils. The solubilizing test was determined by eye evaluation method through the dissolving performance test for the two oils and measured the transmittance at 890 nm using a UV spectrophotometer to measure the transparency. The results showed that the concentration of surfactant needed to make Bergamot oil available requires approximately more 2 times. It was also found that the concentration of surfactant needed to make the tocoperyl acetate available was about 8 times higher. Experiments on the solubility resulting from pH changes showed stabilized usable solubilizing power even in acidic areas of pH=3.5, neutral areas of pH=7.2, and alkaline areas of pH=1.5. Experiments on the solubility according to pH variation showed good solubility stabilized in acidic areas of pH=3.5, neutral areas of pH=7.2, and alkaline areas of pH=11.5. As an application of cosmetics, the company successfully developed a prescription for moisturizing activity based on these results, it is expected that a wide range of applications will be available for skin care, baby lotion, sensitivity or atopic skin cosmetics.

Effects of Velocity Structures on Tracer Mixing in a Meandering Channel (사행수로에서 유속구조가 추적물질의 혼합에 미치는 영향)

  • Seo, Il Won;Park, Sung Won
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.1B
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    • pp.35-45
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    • 2009
  • In this study, a laboratory experiment has been performed on a S-curved channel with two curved sections. In the experiments, effects of 3-D velocity structures on mixing characteristics of tracer material were investigated. As a result, it was clearly noticed that the primary flow travels taking the shortest course of the meandering channel and has a very ununiform distribution at the bends. The secondary cell which was developing at the first bend disappears at the crossover, and then, at the next bend, secondary cell is re-developing in the opposite direction. The experimental results show that mixing of tracer is significantly affected by the combined action of ununiform primary flow and secondary cell. The ununiform primary flow separates the tracer cloud in the longitudinal direction, and the secondary cell further separates the retarding tracer cloud mainly in the transverse direction. As a result, these complex flow structures cause separation and spreading of tracer cloud both in the longitudinal and in the transverse directions. The measured dimensionless transverse dispersion coefficients calculated using 2-D routing procedure ranges 0.012-0.875, and is generally proportional to width to depth ratio (W/h). The predicted values calculated by the theoretical equation overestimate slightly the measured transverse dispersion coefficients.