Park, Jong-Min;Kim, Yoonju;Kim, Haeun;Kim, Youn-Jung
Journal of Korean Biological Nursing Science
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v.21
no.3
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pp.217-223
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2019
Purpose: Caffeine is the most widely consumed psychostimulant of the methylxanthine class. Among adolescents, high-dose of caffeine consumption has increased rapidly over the last few decades due to the introduction of energy drinks. However, little is known about the time-dependent effect of high doses of caffeine consumption in adolescents. The present study aims to examine the short- and long-term influence of high-dose caffeine on behavior of adolescence. Methods: The animals were divided into three groups: a "vehicle" group, which was injected with 1 ml of phosphate-buffered saline for 14 days; a "Day 1" group, which was injected with caffeine (30 mg/kg), 2 h before the behavioral tests; and a "Day 14" group, which was infused with caffeine for 14 days. An open-field test, a Y-maze test, and a passive avoidance test were conducted to assess the rats'activity levels, anxiety, and cognitive function. Results: High-dose caffeine had similar effects in short-and long-term treatment groups. It increased the level of locomotor activity and anxiety-like behavior, as evidenced by the increase in the number of movements and incidences of rearing and grooming in the caffeine-treated groups. No significant differences were observed between the groups in the Y-maze test. However, in the passive avoidance test, the escape latency in the caffeine-treated group was decreased significantly, indicating impaired memory acquisition. Conclusion: These results indicate that high-dose caffeine in adolescents may increase locomotor activity and anxiety-like behavior and impair learning and memory, irrespective of the duration of administration. The findings will be valuable for both evidence-based education and clinical practice.
International Journal of Computer Science & Network Security
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v.22
no.11
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pp.63-70
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2022
At the present stage, the main directions of the professional position of a specialist in the implementation of English-language Education are to improve and spread the practice of learning languages throughout a person's life by involving information, communication and digital technologies in the educational process. Computerization of the educational process in Higher Education Institutions is considered as one of the first and most promising areas for improving the quality of education in Higher Education Institutions. The necessity of ensuring timely training and retraining of specialists of various profiles (in particular teachers) on the effective use of domestic and foreign electronic resources with the help of modern information technologies for the implementation of the professional position of a future specialist in a foreign-language environment is noted. The main goal of teaching a foreign language (the formation of students' communicative competence, which means mastering the language as a means of intercultural communication) is defined. The types of speech activity that cover the content of teaching a foreign language are highlighted. The main types of assessment in a foreign language are shown - current (non-classroom), thematic, semester, annual assessment and final state certification. The task of the teacher is drawn, which is to create conditions for practical language acquisition for each student, to choose such teaching methods by means of information technologies that would allow each student to show their activity, their creativity; to activate the cognitive activity of the student in the process of learning a foreign language.
Purpose: The diagnostic utility of fluorine-18 2-deoxy-D-glucose positron emission tomograhpy ($^{18}F-FDG $PET) for the non-invasive differentiation of focal lung lesions originated from cancer or inflammation disease by combined visual image interpretation and semi-quantitative uptake value analysis has been documented. In general, Standardized Uptake Value(SUV) is used to diagnose lung disease. But SUV does not contain dynamic information of lung tissue for the glucose. Therefore, this study was undertaken to hypothesis that analysis of dynamic kinetics of focal lung lesions base on $^{18}F-FDG$ PET may more accurately determine the lung disease. So we compared Time Activity Curve(TAC), Standardized Uptake Value-Dynamic Curve(SUV-DC) graph pattern with Glucose Metabolic Rate(MRGlu) from Patlak analysis. Methods: With lung disease, 17 patients were examined. They were injected with $^{18}F-FDG$ over 30-s into peripheral vein while acquisition of the serial transaxial tomographic images were started. For acquisition protocol, we used twelve 10-s, four 30-s, sixteen 60-s, five 300-s and one 900-s frame for 60 mins. Its images were analyzed by visual interpretation TAC, SUV-DC and a kinetic analysis(Patlak analysis). The latter was based on region of interest(ROIs) which were drawn with the lung disease shape. Each optimized patterns were compared with itself. Results: In TAC patterns, it hard to observe cancer type with inflammation disease in early pool blood area but over the time cancer type slope more remarkably increased than inflammation disease. SUV-DC was similar to TAC pattern. In the result of Patlak analysis, In time activity curve of aorta, even though inflammation disease showed higher blood activity than cancer, at first as time went by, blood activity of inflammation disease became the lowest. However, in time activity curve of tissue, cancer had the highest uptake and inflammation disease was in the middle. Conclusion: Through the examination, TAC and SUV-DC could approached the results that lung cancer type and inflammation disease type has it's own difference shape patterns. Also, it has outstanding differentiation between cancer type and inflammation in Patlak and MRGlu analysis. Through these analysis methods, it will helpful to separation lung disease.
The significance of Presidential Impeachment in 2004 is subject to interpretations in many different contexts, but its nature as its justice was the constitutional trial by the nation's impeachment system. This study set out to compare and analyze the understanding of the event centered around its nature as "an impeachment event as a public activity" and the records related to it. For that purpose, the study attempted to analyze the impeachment event to understand it as a public activity and examined and analyzed the records of the impeachment event in the public domain through personal visit, phone interview, and request of information disclosure based on the analysis results. An impeachment event as a public activity can be understood as an activity carried out by the National Assembly, which is to issue a motion for impeachment under the norms of the nation's impeachment system, and Constitutional Court, which is responsible for impeachment trial, through their unique rights prescribed in the Constitution. The important subjects of such a public activity included the accused president, the acting presidential system created by the motion for impeachment, and the National Election Commission that provided a decisive ground for impeachment. It was confirmed that the records, which are legal requirements, were well created and have been preserved and managed in the public domain. However, it was difficult to conclude that the records of the impeachment event were thoroughly created in terms of content in relation to affairs as they mainly covered the superficial treatment processes and the results of explicit activities. There was, in particular, the absence of records showing the context of activity.
Journal of the Korea Academia-Industrial cooperation Society
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v.21
no.6
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pp.70-77
/
2020
Configuration management is an important project management method. Configuration management is increasing daily and improving defense power as a management tool for technical data of power support systems. Configuration management work must be carried out properly from the beginning of development to acquire an excellent weapon system. In procurement, configuration management is a vital factor that can determine the cost of maintaining operations during the transfer of military supplies and carry out systematic management among operational support. Countries are making changes to policies and systems to manage R&D, standards, and patents in conjunction with each other from the beginning of research and execution, and it is important to establish the concept of managing and controlling the configuration as an efficient means of managing military resources. To identify the activity details during the entire life cycle from the beginning of acquisition to the end of disposal by linking munitions configuration control with the total life cycle, and redefine the appropriate work system, this study investigated and analyzed the U.S. configuration control procedures to identify the activity details and present areas to develop.
Journal of Elementary Mathematics Education in Korea
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v.1
no.1
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pp.87-98
/
1997
A practice is classified into the practice as a content and the practice as a method. The former means that the practical nature of mathematical knowledge itself should be a content of mathematics and the latter means that one should teach the mathematical knowledge in such a way as the practical nature is not damaged. The practical nature of mathematics means mathematician's activity as it is actually done. Activities of the mathematician are not only discovering strict proofs or building axiomatic system but informal thinking activities such as generalization, analogy, abstraction, induction etc. In this study, it is found that the most instructive ones for the future users of mathematics are such practice as content. For the practice as a method, students might learn, by becoming apprentice mathematicians, to do what master mathematicians do in their everyday practice. Classrooms are cultural milieux and microsoms of mathematical culture in which there are sets of beliefs and values that are perpetuated by the day-to-day practices and rituals of the cultures. Therefore, the students' sense of ‘what mathematics is really about’ is shaped by the culture of school mathematics. In turn, the sense of what mathematics is really all about determines how the students use the mathematics they have learned. In this sense, the practice on which classroom instruction might be modelled is that of mathematicians at work. To learn mathematics is to enter into an ongoing conversation conducted between practitioners who share common language. So students should experience mathematics in a way similar to the way mathematicians live it. It implies a view of mathematics classrooms as a places in which classroom activity is directed not simply toward the acquisition of the content of mathematics in the form of concepts and procedures but rather toward the individual and collaborative practice of mathematical thinking.
When plants are exposed to subfreezing temperatures ice crystals are forming within extracelluar space in leaves. The growth of ice crystal is closely related to the degree of freezing injury. It was shown that an antifreeze protein binds to an ice nucleator through hydrogen bonds to prevent growth of ice crystal and also reduces freezing damage. The antifreeze proteins in plants are similar to PR proteins but only the PR proteins induced upon cold acclimation were shown to have dual functions in antifreezing as well as antifungal activities. Three of the genes encoded for CLP, GLP, and TLP were isolated from barley and Kentucky bluegrass based on amino acid sequence revealed after purification and low temperature-inducibility as shown in analysis of the protein. The deduced amino acid of the genes cloned showed a signal for secretion into extracellular space where the antifreezing activity sup-posed to work. The western analysis using the antisera raised against the antifreeze proteins showed a positive correlation between the amount of the protein and the level of freeze tolerance among different cultivars of barely. Besides it was revealed that TLP is responsible for a freeze tolerance induced by a treatment of trinexapac ethyl in Kentucky bluegrass. Analysis of an overwintering wild rice, Oryza rufipogon also showed that an acquisition of freeze tolerance relied on accumulation of the protein similar to CLP. The more direct evidence for the role of CLP in freeze tolerance was made with the analysis of the transgenic tobacco showing extracellular accumulation of CLP and enhanced freeze tolerance measured by amount of ion leakage and rate of photosynthetic electron transport upon freezing. These antifreeze proteins genes will be good candidates for transformation into crops such as lettuce and strawberry to develop into the new crops capable of freeze-storage and such as rose and grape to enhance a freeze tolerance for a safe survival during winter.
The purpose of this study is to investigate on Humint, one of the intelligence activity conducted by police officer to prevent the possibility of crime in advance and to handle crime in short time. Also, this study aims to identify how interpersonal relationship of police influences Humint acquisition in order to find out the influence of Humint on actual policy activity. For completion, this study conducted survey on current police officer and developed the study based on these data. Humint refers to information acquired by contact between people and to information acquired by intangible contact. Humint, the intangible information, is delivered fast and identifies the other's hidden intention. Humint also approaches inaccessible information and has strength of acquiring information based on five senses instead of using machine. Humint plays vital role in human relations. The investigation on the influence of level, trust, and range of human relations on Humint application demonstrated that people with wide human relations applied Humint effectively on identifying trend. Also, people with wide range of human relations used Humint effectively when utilizing information to handle the crime.
Proceedings of the Korea Society of Environmental Toocicology Conference
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2002.10a
/
pp.156-156
/
2002
The goal of this study is to develop a biomarker used in monitoring abnormal behaviors of Japanese medaka (Oryzias latipes) as a model organism caused by hazardous chemicals that are toxic and persistent in the ecosystem. A widely used insecticide, diazinon (O, O-diethyl O- (2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothioate), is highly neurotoxic to fish, and it is also well known that it causes vertebral malformation and behavioral changes of fish at relatively low concentrations. The fish behaviors were observed on a real time basis using an image processing and automatic data acquisition system. The genes potentially involved in the abnormal behaviors were cloned using suppression subtractive hybridization (SSH) technique. The untreated individuals showed common behavioral characteristics. When the test fish was affected by diazinon at a concentration of 0.1 and 1 ppm, some specific patterns were observed in its behavioral activity and locomotive tracks. The typical patterns were enhanced surfacing activity, opercular movement, erratic movement, tremors and convulsions as reported previously. The number of genes up-regulated tty diazinon treatment were 97 which includes 27 of unknown genes. The number of down-regulated genes were 99 including 60 of unknown genes. These gene expression patterns will be analyzed by the artificial neural networks such as self organization map (SOM) and multilayer perceptron (MLP), revealing the role of genes responsible for the behaviors. These results may provide molecular biological and neurobehavioral bases of a biomonitoring system for diazinon using a model organism such as fish.
Kim, Yong-Hwan;Park, Sung-Seek;Kim, Woo-Jung;Kim, Nam-Jin;Hyun, Myung-Taek
Journal of the Korean Solar Energy Society
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v.34
no.5
/
pp.73-80
/
2014
This study introduces and analyzes the geothermal energy availability in Non-active volcanic region. Jeju island in Korea is situated in non-active volcanic region. The island is composed of rock with high pore and clinker, scoria geological layer formed by volcanic activity about two million ago. Volcanic geological layers with porous characteristics have air, vapor, water and a underground structure through which air or water can move easily. For this reason, it is probable that the mechanism of energy acquisition is by convective heat transfer. For this presumption, the availability of underground air as energy source has been studied here through theoretical analysis and experimental data. The energy output of our system ranged from 2,485,076 kJ/day to 4,060,978 kJ/day monitored using variable velocity air flow controller. Our system has capability to be a reliable energy source irrespective of environmental changes. Consequently, underground air can be utilized for energy source and provide the optimal design of heating/cooling system.
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