• Korean Journal of Health Education and Promotion
• /
• v.16 no.2
• /
• pp.1-17
• /
• 1999

AIDS (Acquired Immunodeficiency Syndrome) known as 20th century's pest is spreading rapidly internationally, and the number of patients are increasing. Since the prevention vaccine has not been developed yet, the only available effective method for preventing AIDS is the health education. Most of the AIDS-infected persons are males, and especially over twenties of age. Therefore, it is necessary to measure the knowledge and attitudes on AIDS of male workers. The purpose of this study is to examine the knowledge, attitudes and education-needs of male workers on AIDS. The data were collected by a questionnaire survey of 977 workers who work in Seoul and Kyungki areas from September 1 thru October 4, 1997. The results were as follows: 1. We examined the level of knowledge on AIDS transmission, symptoms, diagnoses, and prevention methods. Even though respondents had a moderate level of AIDS-related knowledge, still sizable numbers believed that AIDS could be transmitted through casual contact. White-collar workers, higher education groups, higher income groups or those with age thirties showed respectively higher level of knowledge than the other comparison groups. 2. 85％ of the respondents recognized AIDS as a serious problem. Statistical analysis revealed that white-collar workers, higher education groups or those with age twenties had more positive attitudes towards a AIDS patient than their counterparts. 3. Over 80％ of the respondents replied that AIDS education in schools, work places, social agencies or by mass-media was necessary. 62.8％ of the respondents mentioned that government should play the major role in developing AIDS education program. 4. The prediction model of AIDS-education needs was examined with using the multiple logistic regression method. The education level and AIDS-related knowledge were turned to be statistically significant factors influencing positively the perceived needs of AIDS education.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.43 no.1
• /
• pp.29-36
• /
• 2017

Objectives: Acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). People with AIDS are much more vulnerable to infections, including opportunistic infections and tumors, than people with a healthy immune system. The objective of this study was to correlate oral lesions associated with HIV/AIDS and immunosuppression levels by measuring clusters of differentiation 4 (CD4) cell counts among patients living in the middle western regions of Ghana. Materials and Methods: A total of 120 patients who visited the HIV clinic at the Komfo Anokye Teaching Hospital and the Regional Hospital Sunyani of Ghana were consecutively enrolled in this prospective and cross-sectional study. Referred patients' baseline CD4 counts were obtained from medical records and each patient received an initial physician assessment. Intraoral diagnoses were based on the classification and diagnostic criteria of the EEC Clearinghouse, 1993. After the initial assessment, extra- and intraoral tissues from each enrolled patient were examined. Data analyses were carried out using simple proportions, frequencies and chi-square tests of significance. Results: Our study included 120 patients, and was comprised of 42 (35.0%) males and 78 (65.0%) females, ranging in age from 21 to 67 years with sex-specific mean ages of 39.31 years (males) and 39.28 years (females). Patient CD4 count values ranged from 3 to 985 cells/mL with a mean baseline CD4 count of 291.29 cells/mL for males and 325.92 cells/mL for females. The mean baseline CD4 count for the entire sample was 313.80 cells/mL. Of the 120 patients we examined, 99 (82.5%) were observed to have at least one HIV-associated intraoral lesion while 21 (17.5%) had no intraoral lesions. Oral candidiasis, periodontitis, melanotic hyperpigmentation, gingivitis and xerostomia were the most common oral lesions. Conclusion: From a total of nine oral lesions, six lesions that included oral candidiasis, periodontitis, melanotic hyperpigmentation, gingivitis, xerostomia and oral hairy leukoplakia were significantly correlated with declining CD4 counts.

• Tuberculosis and Respiratory Diseases
• /
• v.46 no.4
• /
• pp.574-579
• /
• 1999

Cytomegaloviruses (CMVs) are ubiquitous but highly species-specific agents which commonly infect many animals, including humans. Cytomegalovirus (CMV) pneumonia has been one of the most important opportunistic infections in the immunocompromised host for those who have acquired immunodeficiency syndrome (AIDS) or who have received kidney, bone marrow or other organs. Cytomegalovirus infection has been known to be associated with congenital, infantile and adult nephrotic syndrome. We report a rare case of CMV pneumonia with nephrotic syndrome in a 62-year-old female who recovered fully with ganciclovir.

• Journal of Digital Convergence
• /
• v.13 no.11
• /
• pp.255-265
• /
• 2015

This study was done to identify the levels of knowledge and attitude toward HIV/AIDS in professional graduate medical school students. A cross-sectional survey was used, and data were collected in 2014. Participants were 97 students in South Korea. Data were analyzed using SPSS WIN 19.0 program. The mean score for HIV/AIDS knowledge was 8.91 and attitude was 7.00 out of 15. The levels of HIV/AIDS knowledge and attitude were not statistically significantly different according to participants' general characteristics. There was a statistically significant correlation between the levels of HIV/AIDS knowledge and attitude. Medical students having a high HIV/AIDS knowledge level tended more towards a positive attitude. These findings can be used in developing effective education strategies for medical students and health care providers to increase knowledge and decrease negative attitude toward HIV/AIDS.

• Journal of Korean Neurosurgical Society
• /
• v.46 no.4
• /
• pp.413-416
• /
• 2009

Since the start of the antibiotic era, syphilis has become rare. However, in recent times, it has tended to be prevalent concomitantly with human immunodeficiency virus (HIV) infection and coinfection in North America and Europe. Now, such cases are expected to increase in elsewhere including Korea. A 40-year-old male patient visited hospital complaining of a headache for about one month. Brain computed tomography and magnetic resonance imaging, showed leptomeninged enhancing mass with edema an right porisylvian region, which was suspected to be glioma. Patient underwent a blood test and was diagnosed with syphilis and acquired immune deficiency syndrome. Partial cortical and subcortical resection were performed after small craniotomy. The dura was thick, adhered to the brain cortex, and was accompanied by hyperemic change of the cortex. The pathologic diagnosis was meningovascular syphilis (MS) in HIV infection. After the operation, the patient was treated with aqueous penicillin G. Thereafter, he had no neurological deficit except intermittent headache. At first, this case was suspected to be glioma, but it was eventually diagnosed as MS in HIV coinfection. At this point the case was judged to be worth reporting.

• Bulletin of the Korean Chemical Society
• /
• v.34 no.8
• /
• pp.2466-2472
• /
• 2013

Human immunodeficiency virus type-1 (HIV-1) is a causative agent of Acquired immunodeficiency syndrome (AIDS), which has affected a large population of the world. Viral envelope glycoprotein (gp120) is an intrinsic protein for HIV-1 to enter into human host cells. Molecular docking guided molecular dynamics (MD) simulation was performed to explore the interaction mechanism of heterobiaryl derivative with gp120. MD simulation result of inhibitor-gp120 complex demonstrated stability. Our MD simulation results are consistent with most of the previous mutational and modeling studies. Inhibitor has an interaction with the CD4 binding region. Van der Waals interaction between inhibitor and Val255, Thr257, Asn425, Met426 and Trp427 were important. This preliminary MD model could be useful in exploiting heterobiaryl-gp120 interaction in greater detail, and will likely to shed lights for further utilization in the development of more potent inhibitors.

• Journal of Digital Convergence
• /
• v.16 no.4
• /
• pp.277-288
• /
• 2018

This study investigated the correlations of the AIDS knowledge, self-esteem, sense of control, optimistic bias toward AIDS, and condom use in the Chinese male college students. A cross-sectional survey was used, and 307 male students were recruited from anonymous universities in cities of two provinces in China. The data were analyzed according to descriptive statistics, ANOVA, Pearson's correlations. The Chinese male college students had an optimistic bias toward AIDS. The score of AIDS knowledge was 73%, and the self-esteem and sense of control scores were all rated higher than the median. The difference among groups according to grade and age were statistically significant in this study. The self-esteem, sense of control, and optimistic bias toward AIDS showed significant positive correlations, but AIDS knowledge, optimistic bias, and condom use have no correlations. The studies that examine psychological variables with condom use among various groups should be followed in the Chinese context.

• Journal of Korean Academy of Nursing Administration
• /
• v.15 no.1
• /
• pp.91-105
• /
• 2009

Purpose: The aim of this study was to analyze the needs of HIV/AIDS care and to develop the job description of HIV/AIDS Counselling nurse in Korea. Methods: The needs assessment was done by focus group interview with HIV/AIDS care recipients who are 16 persons living with HIV/AIDS and four their family members, seven persons from HIV/AIDS high risk group, and five nurses working on HIV/AIDS clinics. Based on the result of needs assessment, job description was developed using the DACUM. Mail survey was done to identify the frequency, importance, and difficulty of duties, tasks, and task elements. Results: The job description was classified under 8 duties, 36 tasks, and 290 task elements. Duties were categorized as needs assessment, health promotion and quality of life, improvement of treatment compliance, symptom care, health education, resource network, administrative activity, and career development. The importance of all duties and tasks showed high score from the survey, but the frequency and the performance level were middle range. Conclusion: It is suggested that the special training program based on the job description needs to be developed. In the political aspects, the introduction of HIV/AIDS nurse specialist certification could be considered.

• Journal of Institute of Control, Robotics and Systems
• /
• v.17 no.8
• /
• pp.753-759
• /
• 2011

The HIV (Human Immunodeficiency Virus) causes AIDS (Acquired Immune Deficiency Syndrome). The process of infection and mutation by HIV can be described by a 3rd order state equation. For this HIV model that includes the dynamics of the mutant virus, we present a parameter estimation scheme using two state variables sporadically measured, out of the three, by employing a genetic algorithm. It is assumed that these non-uniformly sampled measurements are subject to random noises. The effectiveness of the proposed parameter estimation is demonstrated by simulations. In addition, the estimated parameters are used to analyze the equilibrium points of the HIV model, and the results are shown to be consistent with those previously obtained.

• Parasites, Hosts and Diseases
• /
• v.53 no.6
• /
• pp.705-712
• /
• 2015

Intestinal parasitic infections are one of the major causes of diarrhea in human immunodeficiency virus (HIV) seropositive individuals. Antiretroviral therapy has markedly reduced the incidence of many opportunistic infections, but parasite-related diarrhea still remains frequent and often underestimated especially in developing countries. The present hospital-based study was conducted to determine the spectrum of intestinal parasitosis in adult HIV/AIDS (acquired immunodeficiency syndrome) patients with or without diarrhea with the levels of $CD4^+$ T-cell counts. A total of 400 individuals were enrolled and were screened for intestinal parasitosis. Of these study population, 200 were HIV seropositives, and the remaining 200 were HIV uninfected individuals with or without diarrhea. Intestinal parasites were identified by using microscopy as well as PCR assay. A total of 130 (32.5%) out of 400 patients were positive for any kinds of intestinal parasites. The cumulative number of parasite positive patients was 152 due to multiple infections. A significant association of Cryptosporidium (P<0.001) was detected among individuals with $CD4^+$ T-cell counts less than $200cells/{\mu}l$.