• 대한방사선방어학회:학술대회논문집
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• 2009.04a
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• pp.90-91
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• 2009

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• Korean Journal of Veterinary Research
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• v.19 no.2
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• pp.99-105
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• 1979

In order to know the histological changes of rat preputial gland during normal sexual cycle and sex hormone treatment, matured Wistar rats (B.W.about 200g) were used for the experiment. Rats were subcutaneously given $2{\mu}g$ 17-${\beta}$-estradiol (Sigma) and 2.5g progesterone (Nakarai Chem., Japan) daily in 0.5ml propylen glycol for ten days respectively. The results obtained are as follow: At the stage of estrus and metestrus, the eosinophilic crystalloid granules and large vacuoles in the acinar cells appeared numerously, and the excretory ducts were severely extended. The developed connective tissue between the acinus were also found. At the stage of proestrus and diestrus, however, the small vacuoles and a few eosinophilic crystalloid granules appeared in the acinar cell. In the estradiol treatment, on the other hand, severely extended excretory ducts and a small number of the eosinophilic crystalloid granules compared with the progesterone treatment were found. The cyst-like structure was found, and in that the acinus disappeared completely. In the progesterone treatment, remarkably extended excretory ducts and nomerous appearance of oval formed eosinophilic granules in the acinar cells were found. As these findings, it could be suggested that the secretion of rat preputial gland was active at the estrus and metestrus stage, and estrogen may concerned in the secretion, land progesterone in the formation of secretory products.

• Journal of Aquaculture
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• v.21 no.4
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• pp.252-258
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• 2008

Gonadal development and reproductive cycle of the ark shell Scarpharca subcrenata were investigated by histological observations. Samples were collected monthly from March 2007 to February 2008 in the Yeoja Bay, Yeosu, Jeollanam-do, Korea. S. subcrenata was dioecious. The gonads consist of a number of oogenic follicle and acinus. Monthly changes in the gonad index reached a maximum in June and a minimum in September. Monthly changes in the condition index reached a maximum in April and a minimum in September. The reproductive cycle of this species can be divided into five successive stages: early active stage (January to April), late active stage (March to June), ripe stage (May to August), spent stage (July to September) and recovery and resting stage (September to March). The main spawning of S. subcrenata occurred in July and August in Yeoja Bay. The sex ratio of female to male was not significantly different from 1:1.

• The Korean Journal of Malacology
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• v.23 no.2
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• pp.165-172
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• 2007

Gonadal development, reproductive cycle and sex ratio of the purplish Washington clam, Saxidomus purpuratus were investigated monthly by histological observations. Samples were collected from May 2006 to April 2007 in the Gangjin Bay of Namhea, Gyeongsangnam-do, Korea. The clams are dioecious. The gonads consist of a number of oogenic follicle and acinus. Monthly changes in the gonad index reached a maximum in April and a minimum in July. Monthly changes in the condition index reached a maximum in June and a minimum in November. The reproductive cycle of this species can be divided into five successive stages: the recovery and resting stage (June to December), early active stage (January to April), late active stage (February to July), ripe stage (March to October), spent stage (April to October). The main spawning of the clam occurred in July and September in Gangjin Bay. The sex ratio of female to male was not significantly different from 1:1.

• Journal of Aquaculture
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• v.22 no.1
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• pp.34-41
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• 2009

Gonadal development and reproductive cycle of the granular ark Tegillarca granosa were investigated by histological observations. Samples were collected monthly from January to Decemberry 2002 in the Yeoja Bay of Yeosu, Jeollanam-do, Korea. T. granosa was dioecious. The gonads consist of a number of oogenic follicle and acinus. Monthly changes in the gonad index reached a maximum in June and a minimum in August. Monthly changes in the condition index reached a maximum in July and a minimum in September. The reproductive cycle of this species can be divided into five successive stages: early active stage (March to May), late active stage (April to June), ripe stage (May to July), spent stage (July to August) and recovery and resting stage (September to March). The spawning of T. granosa occurred in July and August in Yeoja Bay. The sex ratio of female to male was not significantly different from 1:1.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.697-698
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• 2002

The dispersion of an aerosol bolus in acinus is analyzed numerically. Model geometry is a straight duct surrounded by an axisymmetric semicircular annulus which is expanding or contracting with breathing. Unsteady Wavier-Stokes equation is solved by CFX-F3D, an FVM commercial code and the trajectory of massless particle Is computed by Lagrangian method. For steady flow with no wall motion, mean velocity of aerosol bolus in alveolated duct is a little smaller than that in straight duct and dispersion in alveolated duct is comparable with the dispersion in straight tube. For expanding duct mean velocity of aerosol bolus approaches half of that in straight tube and effective diffusivity is smaller than that of straight tube. For contracting duct mean velocity of aerosol bolus becomes slightly larger than that in straight tube and effective diffusivity is comparable with the case of straight tube.

• The Korean Journal of Cytopathology
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• v.8 no.1
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• pp.76-82
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• 1997

Two cases of pulmonary atypical carcinoid tumor were diagnosed by fine needle aspiration cytology. Although the cytologic features of atypical carcinoid tumor have been relatively well described, it is easy to confuse atypical carcinoid tumor with typical carcinoid tumor, small cell carcinoma and adenocarcinoma of the lung. Atypical carcinoid tumor has been recognized as a distinct variant of pulmonary neuroendocrine carcinoma, with characteristic histopathologic and clinical features that separate it from both carcinoid and small cell carelnoma. The distinction of atypical carcinoid tumor from small cell carcinoma has important prognostic and therapeutic implications. The cytologic characteristics of atypical carcinoid tumor included polygonal to fusiform cells with a variable amount of lacy cytoplasm, oval nuclei with coarsely dispersed chromatin and frequent nucleoli, and mild pleomorphism. The malignant cells were arranged either in acinus-like clusterg or in epithelial sheets.

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.265-276
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• 1996

This study was performed to identify the localization of several neuropeptides; calcitonin gene-related peptide(CGRP), substance P(SP), vasoactive intestinal polypeptide(VIP), neuropeptide Y(NPY), serotonin(5-HT) and neurotensin in the tongue of Korean native goat(Capra hircus) by immunohistochemical method. The results were summarized as follows: CGRP- and SP-immunoreactive fibers were observed as moderate immunoreactivity at the subepithelial plexus and subgemmal fibers in lamina propria of lingual papillae, but not seen in intragemmal, intergemmal, perigemmal fibers as well as in the supporting, basal and taste cells. Fibers around the acinus of the von Ebner's gland and blood vessels showed weak immunoreactivities against CGRP and SP. In the intrinsic ganglion cells, CGRP- and SP-immunoreactivities were not observed. The distribution patterns of VIP- and NPY-immunoreactive fibers were similar to CGRP-or SP-immunoreactive fibers, but their immunoreactivities were stronger than those of CGRP- or SP immunoreactive fibers. The immunoreactivities to VIP or NPY were seen in the intrinsic ganglion. Only a few serotonin immunoreactive fibers were seen in some filiform or fungiform papillae. Neurotensin immunoreactivity was not observed in the tongue of Korean native goat.

• Applied Microscopy
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• v.25 no.3
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• pp.40-50
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• 1995

The results of observation on the salivary gland and salivary secretory duct of Korean slug, Incilaria fruhstorferi, in histochemical method are as follows. It is observed that there are six kinds of gland cells(Type-A, B, C, E and F) making up the salivary gland of Korean slug. Of those, type-A gland cell is observed as an acid mucous cell, and type-B, C, D, F gland cells as neutral mucous cells. But in type-E gland cell, while the membrane surrounding granules exhibit alcianophilia, granules show no reaction. The salivary secretory duct composing the salivary gland of Korean slug is composed of supporting epithelial cell and four kinds of gland cells(type-A, E, F and G), of which type-A, E, F gland cells compose both the acinus of salivary gland and endothelial tissue of salivary secretory duct, and are secreted into lumen through salivary secretory duct. But, type-G gland cell is observed only in the endothelium of salivary secretory duct and mucous granules are observed as neutral mucopolysaccharide.

• Herbal Formula Science
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• v.13 no.2
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• pp.71-91
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• 2005

A/J mice injected with urethane(1mg/ g of body weight) develop tumors with distinct histological patterns, which are classified as solid and papillary. I divided the mice into 3 groups; control group treatment with saline, BYA group treatment with herbal formula, Bopheyangyoungjeon 0.3g/kg and BYB groups treatment with herbal formula 1.5g/kg. The administration of herbal medicine was done every day for 56 days. The experimental results from herbal medicine treatment were compared to those from a saline-treated control group. Serial sections of the whole lung(150 to 200 sections per mouse) showed solid and papillary tumors arose from the pulmonary acinus, invading the bronchioles only as the tumors grew. The number of tumor, in the 8-weeks groups, are decreased in the experimental groups compared to control group. COX-2 protein and IGF- I protein expression was more increased in lung tumors of the control group compared to BYA and BYB groups. These results suggest that Bopheyangyoungjeon extract suppress the carcinogenesis of lung in the A/J mouse.