• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7265-7270
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• 2013

Objective: The present study was designed to investigate the probable mechanisms of synthetic retinoid 4-amino-2-tri-fluoromethyl-phenyl ester (ATPR) inhibition of the proliferation and migration of A549 human lung carcinoma cells. Materials and Methods: After the A549 cells were treated with different concentrations of ATPR or all-trans retinoic acid (ATRA) for 72 h, scratch-wound assays were performed to assess migration. Immunofluorescence was used to determine the distribution of CAV1 and $RXR{\alpha}$, while expression of CAV1, MLCK, MLC, P38, and phosphorylation of MLC and P38 were detected by Western blotting. Results: ATPR could block the migration of A549 cells. The relative migration rate of ML-7 group had significantly decreased compared with control group. In addition, ATPR decreased the expression of a migration related proteins, MLCK, and phosphorylation of MLC and P38. ATPR could also influence the expression of RARs or RXRs. At the same time, CAV1 accumulated at cell membranes, and $RXR{\alpha}$ relocated to the nucleus after ATPR treatment. Conclusions: Caveolae may be implicate in the transport of ATPR to the nucleus. Change in the expression and distribution of $RXR{\alpha}$ may be implicated in ATPR inhibition of A549 cell proliferation. The mechanisms of ATPR reduction in A549 cell migration may be associated with expression of MLCK and phosphorylation of MLC and P38.

• The Korean Journal of Pesticide Science
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• v.4 no.2
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• pp.44-49
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• 2000

Objective of this study was to determine the Si distribution and extent of control of powdery mildew diseases of cucumber(Cucumis sativus L.). The distribution of silicon in the leaf epidermis of cucumber plants grown in hydroponic nutrient solutions supplemented with soluble silicates was examined using scanning electron microscopy and energy dispersive X-ray analysis. The silicate absorbed from nutrient solution was translocated into cucumber leaves, and accumulated mainly in the cells surrounding the base of trichome hairs. Base cells surrounding the trichomes also had high levels of Si, Ca, and K. Si levels in the epidermal cells for low Si treatment were not detectable except in the trichome bases. Hyphal lengths of powdery mildew occurring on cucumber leaves cultivated in medium with high concentration of silicate were remarkably shorter than those of cucumber leaves cultivated with low concentration of silicate. There was a negative correlation between hyphal length of S. fuliginea and silicate concentrations.

• The Journal of Industrial Distribution & Business
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• v.10 no.6
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• pp.51-58
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• 2019

Purpose - Prior studies reported that the opacity of information caused stock price crash. If managers fail to disclose unfavorable information about the firm over a long period of time, the stock price is overvalued compared to its original value. If the accumulated information reaches a critical point and spreads quickly to the market, the stock price plunges. Information management by management's disclosure policy can cause information uncertainty, which will lead to a plunge in stock prices in the future. Thus, this study aims at examining the impact of disclosure quality on crash risk by focusing on the unfaithful disclosure firms. Research design, data, and methodology - This study covers firms listed on KOSPI and KOSDAQ from 2004 to 2013. Firms excluded from the sample are non-December firms, capital-eroding firms, and financial firms. The financial data used in the research was extracted from the KIS-Value and TS2000 database. Unfaithful disclosure firm designation data was collected from the Korea Exchange's electronic disclosure system (kind.krx.co.kr). Stock crash is measured as a dummy variable that equals one if a firm experiences at least one crash week over the fiscal year, and zero otherwise. Results - Empirical results as to the relation between unfaithful disclosure corporation designation and stock price crashes are as follows: There was a significant positive association between unfaithful disclosure corporation designation and stock price crash. This result supports the hypothesis that firms that have previously exhibited unfaithful disclosure behavior are more likely to suffer stock price plunges due to information asymmetry. Second, stock price crashes due to unfaithful disclosures are more likely to occur in Chaebol firms. Conclusions - While previous studies used estimates as a proxy for information opacity, this study used an objective measure such as unfaithful disclosure corporation designation. The designation by Korea Exchange is an objective evidence that the firm attempted to conceal and distort information in the previous year. The results of this study suggest that capital market investors need to investigate firms' disclosure behaviors.

• Korean Journal of Soil Science and Fertilizer
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• v.49 no.6
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• pp.644-650
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• 2016

In soil-to-plant transfer of heavy metals, the amount absorbed and accumulated varies depending on the environment conditions. The absorption rate of cadmium (Cd) in plants differs considerably depending on the bioavailability of Cd in the soil, while usage by various organic matters is also reported to affect absorption patterns. Therefore, this study aimed to identify the difference in the transfer of essential metal ions and Cd to various plant parts when rice straw compost was used to cultivate soybean (Glycine max L. cv. Daepung). In the two-leaf stage of soybean cultivated in a greenhouse, Cd was mixed in the soil, after which the Cd and essential metal ions contents, and physiological changes of soybean seedlings were studied on the 15th and 25th day. The Cd toxicity in the plant was reduced with the use of rice straw compost. Further, the Cd content varied with the plant part, and was higher in young leaves (3rd and 4th leaf) than in the stem. When analyzed by leaf age, the Cd transfer was highest in young leaves (3rd and 4th leaf), followed by mature leaves (1st and 2nd leaf). While there was no significant difference between plant tissues in the absorption rate of copper (Cu) and zinc (Zn) when rice straw compost was used against Cd toxicity, the absorption rate of manganese (Mn) and iron (Fe) showed a significant decline in both the control and rice straw compost treatment conditions, as well as a significant difference between leaf ages. Therefore, these results confirm that the use of rice straw compost against Cd toxicity is effective, and implies that the rate of Cd transfer in the soybean plant varies significantly with leaf age.

• Proceedings of the Korean Geotechical Society Conference
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• 2004.03b
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• pp.592-599
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• 2004

Talus topography is that weathered rock clasts were accumulated dropping in steep slope to action of gravity. Rock fall talus is formed by the accumulation of rock debris falling as individual particles from a cliff. If the collapse is produced in talus slope. it will be possible the loss of manpower and country. Despite correct access about talus is required, domestic research was scientific access about talus short because of short resolution of aerophoto and difficulties of research about huge talus. In this Study, Our research team analgize the wetness index using the geomorphogical data. Lineament through wetness index is simillar with distribution of the talus. And, the aim of the present study is to review and compare fabric data derived from rock fall talus about orientation, distribution and morphology. These deposits tend to have approximately equal amounts of clasts oriented parallel and perpendicular to the dip direction of the slope. And, platy- shaped clasts dominate the proximal and intermediate parts of the talus, wheres blocky-shaped clasts is more common in the distal part. we carry out Rock Fall Simulation. And, We install criteria of the rockfall protective barrier using talus and geomorphological characteristics.

• Atmosphere
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• v.26 no.3
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• pp.435-444
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• 2016

In spite of considerable progress in the recent decades, there still remain large uncertainties in numerical cloud models. In this study, effects of uncertainty in terminal velocity of graupel on cloud simulation are investigated. For this, a two-dimensional bin microphysics cloud model is employed, and deep convective clouds are simulated under idealized environmental conditions. In the sensitivity experiments, the terminal velocity of graupel is changed to twice and half the velocity in the control experiment. In the experiment with fast graupel terminal velocity, a large amount of graupel mass is present in the lower layer. On the other hand, in the experiment with slow graupel terminal velocity, almost all graupel mass remains in the upper layer. The graupel size distribution exhibits that as graupel terminal velocity increases, in the lower layer, the number of graupel particles increases and the peak radius in the graupel mass size distribution decreases. In the experiment with fast graupel terminal velocity, the vertical velocity is decreased mainly due to a decrease in riming that leads to a decrease in latent heat release and an increase in evaporative cooling via evaporation, sublimation, and melting that leads to more stable atmosphere. This decrease in vertical velocity causes graupel particles to fall toward the ground easier. By the changes in graupel terminal velocity, the accumulated surface precipitation amount differs up to about two times. This study reveals that the terminal velocity of graupel should be estimated more accurately than it is now.

• Nuclear Engineering and Technology
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• v.20 no.1
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• pp.9-18
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• 1988

Previously determining the fuel loading pattern is based on the trial and error method. For a candidate pattern, the core analysis is performed and the pattern is examined whether it satisfies the imposed constraints such as the power peaking or not. The pattern, then, is revised by the shuffling of assemblies and the revision is repeated until all of the conditions are met. This method unavoidably requires many iterative diffusion calculations, computing times and accumulated experiences. To overcome these disadvantages, a new method which is called backward diffusion calculation is introduced. If the most desirable power distribution is already known, the optimal loading pattern can be obtained by solving the backward diffusion equation with simple calculation. In this study, the basic equation for the backward diffusion calculation is derived and the optimal power and fuel distributions are searched in one-dimensional cylindrical geometry by using the proposed method. In addition, the basis to determine the optimal power and fuel distributions is suggested for the real core geometry.

• 한국해양학회지
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• v.21 no.3
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• pp.146-155
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• 1986

Zooplankton samples of upper 50m layer in May, 1985 and of various depth intervals depending on thermal structure in October, 1985 were analyzed. Standing stock represents mean of 538inds/㎥ in spring and 267 inds/㎥ and 508inds/㎥ of whole column mean and surface layer in fall, respectively. A total of 55 and 104taxa is identified in each season and accumulated data list at least 123 species inhabiting in the study area. Copepods dominate in the zooplankton community, followed by protozoans and appendicularians in both seasons. In surface layer, distribution of subtropical species and standing stock seems to illuminate the effects of the Tsushima Current and the North Korean Cold Watermass in cold season, whereas only standing stock shows discernable variation in warm season. Concerning whole water column, depth of permanent thermocline bottom, at about 120m in fall 1985, plays significant role as a barrier to the distribution of mesopelagic cold water species. Serial sampling in October, 1985 does not reveal any perceivable diel vertical migration, which is considered to confirm the earlier suggest that owing to the lack of true abyssal species zooplankton biomass of deeper gayer is very poor, so that diel vertical migration of the East Sea is weak.

• Economic and Environmental Geology
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• v.33 no.5
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• pp.425-434
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• 2000

The 3.5 KHz seismic survey was carried out for studying the distribution pattern of the unconsolidated sediments of the Yeosu Sound on the southern coast of the Korean Peninsula. Field data originally recorded in analog are converted and processed digitally to recover the high-resolution acoustic profiles. Across the north-south trending channel with the depth of 20~30 m, different seismic facies types are observed in the top section of sediments. The western part is characterized by the continuous high-amplitude subparallel reflectors within which the acoustic turbidity as a token of the presence of gas is commonly observed, whereas the counterpart largely shows poor reflectors and has shallow acoustic basement toward the north. The dissimilarity of the seismic expression across the channel can be interpreted as the result of the change of depositional environment caused by relative sea-level fluctuations of the late-Quaternary. During the last glacial period, the Yeosu Sound was exposed and eroded by the paleo-Seomjin River. By the following rapid rise of sea level, it was covered by the transgressive sand sheet. When the sea level reached near the present position, the muddy sediment has accumulated only in the western part of the Yeosu Sound as its depositional front has moved toward the north. It is partly caused by the asymmetrical tidal current in the Yeosu Sound where the flood near the bottom has stronger current flow and contains more suspended sediments.

• Journal of Plant Biotechnology
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• v.37 no.2
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• pp.228-235
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• 2010

The establishment of cell suspension culture and plant regeneration of the halophytic Leymus chinensis (Trin.) are described in this study for the first time. Callus induction solid medium containing Murashige and Shoog (MS) basic salt, $2.0\;mg\;l^{-1}$ 2,4-dichlorophenoxyacetic acid (2,4-D), and $5.0\;mg\;l^{-1}$ L-glutamic acid with $30.0\;g\;l^{-1}$ sucrose and $4.0\;g\;l^{-1}$ gelrite for solidification induced the highest rate of cell division in Type 1 callus among calli of various types. Liquid medium with the same hormone distribution was therefore, used for cell suspension culture from Type 1 callus. Over a 30 d suspension culture at 100 rpm, great amounts of biomass were accumulated, with 71.07% average daily increment and 22.32-fold total fresh weight increment. Comparison of before and after suspension culture, the distribution of different size callus pieces and the maintenance of callus type were basically unaltered, but a slight increase in relative water contents was observed. To induce the potential of plant regeneration, the directly transferring on plant regeneration solid medium containing MS basic salt, $0.2\;mg\;l^{-1}$ $\alpha$-naphthalene acetic acid (NAA), $2.0\;mg\;l^{-1}$ kinetin (Kn), and $2.0\;g\;l^{-1}$ casamino acid and indirectly transferring were simultaneously performed. Even now growth rates of suspension-derived callus on solid medium were approximately half of those of Type 1 callus, but faster somatic embryogenesis was observed. Rooting of all regenerated shoots was successfully performed on half-strength MS medium. All plants appeared phenotypically normal.