• 생약학회지
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• 제37권1호통권144호
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• pp.1-10
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• 2006

'O Ga Pi Ip' has been used in Korea to cure rheumatism, neuralgia, edema, dematopathy, and impotence. The botanical origin of the crude drug has not been confirmed pharmacognostically. To clarify the botanical origin of 'O Ga Pi Ip', the morphological and anatomical characteristics of the leaves of Acanthopanax species growing in Korea and Japan, A. chi-isanensis Nakai, A. Koreanum Nakai, A. rufinerve Nakai, A. senticosus (Rupr.et Maxim). Harms, A senticosus (Rupr.et Maxim.) for inermis Harms, A. seoulense Nakai, A sessiliflorus (Rupr. et Maxim.) Seem, A. divaricatus Seem, A. sieboldianum Makino were compared. As a result, it was determined that 'O Ga Pi Ip' was the leaf of A. sessiliflorus (Rupr. et Maxim.) Seem, A chiisanensis Nakai, and A. koreanum $Nakai_I$.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2010년도 심포지엄 및 추계학술발표회
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• pp.461-462
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• 2010

• Journal of Plant Biology
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• 제39권1호
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• pp.15-22
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• 1996

Seventy-three chromosome counts are reported from populations in 70 species from Korea, of which 34 counts in 32 species belong to Apiaceae. New species counts are in Acanthopanax chiisanensis(2n=48), Hydrocotyle japonica(2n=ca.96), H. maritima (n=12), Libanotis coreana (2n=22), Lindera sericea (n=12), Quercus myrsinaefolia (n=12), Rhamnus yoshinoi (n=12), Salix hulteni (n=19), Symplocos chinensis for. pilosa (n=11) and Vaccinium oldhami (n=12). New chromosome level for Asperula odorata (n=11), Cryptotaenia japonica (2n=16) and Sium ninsi (2n=18) is also provided. The taxonomic implications of certain of these counts are discussed.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2000년도 The 7th International Symposium
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• pp.52-63
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• 2000

Many plant species are used in China in traditional medicine for the prevention and treatment of cancer. This paper presents some of these species with details on other pharmacologic evaluation and its traditional Chinese meditional uses. The known bioaktivities and some chemical constituents of each of the species given. Information on bioactivities of each species resulting from tests on experimental animals are given. Many of the known chemical constituents of each species are given. Various species of plants elective for various types. In this meeting I will present on some antitumor of the plants which are as follows; (1) Akebia trifoliata(Thunb.)Koidz. ((2) Panax notoginseng(Burk.) F, H, Chen., (3) Ziziphus jujuba Mill., (4) coriolus versicolor(Fr.)Que l., (5) Trichosanthes kirilowii Maxim., (6) Ficus carica Linnaeus., (7) Acanthopanax senticosus(Rupr.et Maxim.)Harms., (8) Hibiscus mutabilis Linnaeus., (9) Arctium lappa Linnaeus., (11) Agrimonia pilosa Ledebour and (12) Hedyotis diffusa Willd.

• Advances in Traditional Medicine
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• 제3권1호
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• pp.1-7
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• 2003

Some Korean plants were found to inhibit HIV-1 protease activity. The extracts of Acanthopanax koreanum (stem bark), Berchemia berchemiaefolia (stem), Berchemia berchemiaefolia (bark), Distylium racemosum (leaves), Distylium racemosum (stem), Lindera erythrocarpa (leaves), Physalis alkekengi var. francheti (root), Platycarya strobilacea (stem), Rodiola rosea (root), Rosa davurica (stem), Syringa dilatata (leaves), Viburnum awabuki (stem) and Viburnum awabuki (leaves) showed significant inhibitory effect against HIV-1 protease. Camelliatannin H from Camellia japonica and uvaol from Cratagus pinatrifida were potent active inhibitors of HIV-1 protease with $IC_{50}$ values of $0.9\;{\mu}M$ and $5.5\;{\mu}M$, respectively. The cure and prevention of AIDS have been a global challenge since it was discovered in the ealy 1980s. However, the development of anti-HIV agent that can effectively treat or prevent this disease are still demanded.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2012년도 심포지엄 및 춘계학술발표회
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• pp.9-10
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• 2012

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2012년도 심포지엄 및 춘계학술발표회
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• pp.223-224
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• 2012

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.298.1-298.1
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• 2003

The aim of this study was to investigate the protective effect of acanthoic acid on liver injury induced by either tertiary-butyl hydroperoxide (tBH) or carbon tetrachloride in vitro and in vivo. Acanthoic acid, (-)-pimara-9(11),15-diene-19-oic acid, is a diterpene isolated from the root bark of Acanthopanax koreanum. In in vitro study, the cellular leakage of lactate dehydrogenase (LDH) with 1.5 mM tBH for 1 j, were significantly inhibited by treatment with acanthoic acid(25 and 5mg/mL). (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.206.1-206.1
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• 2003

From methanol extract of Acanthopnanax senticosus, six platelet anti-aggregating compounds, chiisanogenin (1), chiisanoside (2), ursolic acid (3), oleanolic acid (4), b-sitosterol (5) and daucosterol (6) were isolated. All of the isolated compounds showed dose-dependent inhibitory activities to rat platelet aggregation induced by all the agonist employed. Compound 1 showed about 50 folds higher potency than acetylsalicylic acid (ASA) on U46619 induced platelet aggregation (IC$\sub$50/ : 6.21 ${\mu}$M) and 10 ∼ 20 folds higher effect than ASA on epinephrine and arachidonic acid (AA) induced aggregation (IC$\sub$50/ ; 2.50 and 4.81 ${\mu}$M, respectively). (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.259.1-259.1
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• 2002

Many polysaccharides isolated from plants are considered to be biological response modifiers and have been shown to enhance various immune responses in vivo and in vitro. Here we demonstrate that a polysaccharide isolated from cell culture of Acanthopanax senticosus (AS) has a unique mode of immunostimulation with regard to its cell-type specificity. AS was found to markedly increase polyclonal IgM antibody production and the proliferation of B cells. and to activate iNOS transcription and NO production in macrophages. (omitted)