• 제목/요약/키워드: Abnormal change

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Laser Doppler를 이용한 자율신경 기능 평가 방법 (Evaluation of the Autonomic Nervous System Using Laser Doppler)

  • 남상희;신정욱;조종만
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1993년도 추계학술대회
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    • pp.51-54
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    • 1993
  • The purpose of this research is to investigate the relationship between the blood flow and autonomic nervous system which regulates the circulation system. After the oral glucose tolerance test(GTT) the velocity changes of the blood flow were measured from the normal, hyperglycemia and diabetic neuropathy using the laser doppler. The FFT analyses showed that the spectrums were concentrated around the particular bands(0.02-0.166Hz, 0.8-1.1Hz) for the normal, while almost uniform distribution of the spectrums was observed for the abnormal. The blood glucose affects the compliance of the blood vessels and viscosity and finally causes the resistance problem in the blood vessels. An index PG was introduced, which was determined by the ratio of the change or the integral power spectrum in the range between 0.02 and 0.166Hz to change of the blood glucose before and after GTT. The index shows 1.0. 0.3 and 0.1 for the normal, hyperglycemia and diabetic neuropathy, respectively. As a conclusion, this spectrum analysis shows the potential of checking the progress or the diabetic, also car be used to evaluate the vasomotion which are regulated by the autonomic nervous system.

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Effects of Brazilin on Lipid and Phosphatidyl Fatty Acid Composition of Erythrocyte Membrane in Streptozotocin-induced Diabetic Rats

  • Moon, Change-Kiu;Yoon, Eun-Yi;Lee, Soo-Hwan;Moon, Chang-hyun;Hwang, Daniel-H.
    • Archives of Pharmacal Research
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    • 제16권2호
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    • pp.147-151
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    • 1993
  • In diabetes, the abnormal increase of the membrane cholesterol/phospholipid ratio (C/PL) is consdered to be the main reason for the decreased membrane fluidity, which then results in impaired erythrocyte deformability and subsequent microcirculatory disturbances. In this study, we examined the effects of brazilin on lipid and phosphatidyl fatty acid composition of erythrocyte membranes in streptozotocin induced diabetic rats. Treatment of brazilin (10mg/kg or 100 mg/kg for 2 weeks, i.p) altered and cholesterol contents in diabetic erythrocyte membranes. The C/PL ratio of brazilin treated groups decreased compared with that of diabetic control group while no change was observed in normal erythrocytes. In streptozotocin induced diabetic rats, alterations in phosphatidyl fatty acid compositioin of erythrocyte membranes were observed and brazilin could reverse these alterations. Arachidonic acid level reumed to a normal level while linoleic acid level remained unchanged by the treatment of brazilin. The results suggest that brazilin might increase erythrocyte membrane fluidity which plays a key role inregulating erythrocyte deformability, thereby it could exert positive effects on microdiculatory disturbances.

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젊은 성인의 척추주위근에 발생한 지방 변성을 동반한 심한 근위축: 증례보고 (Severe Paraspinal Muscle Atrophy with Fatty Degeneration in a Young Adult: A Case Report)

  • 허재원;양원종;박은희;이재은;김철현
    • 대한근전도전기진단의학회지
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    • 제20권2호
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    • pp.130-134
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    • 2018
  • A 36-year-old male patient developed diffuse low back pain. His past medical history was unremarkable and had no family history of neuromuscular disease. He had no bladder and bowel problems. Creatine kinase was 172 U/L (normal < 170). Other fluid and blood chemistry tests were normal. Manual muscle test grades of extremities and sensory examination were normal. Muscle stretch reflexes were normal. Fasciculations and myotonia were not detected. Straight leg raising test was negative. There was no spinal root compression, spinal stenosis, or signal intensity change of spinal cord on magnetic resonance imaging (MRI). Fatty change and atrophy of the cervical, thoracic and lumbar paraspinal muscles were noted on MRI. Nerve conduction studies were normal. Electromyography showed 1+ positive sharp waves in the lumbar paraspinal muscles. Electromyography of upper and lower extremity muscles revealed no abnormal spontaneous activity. We report a rare case of severe paraspinal muscle atrophy with fatty degeneration in a Young Adult.

통계적 공간상세화 기법의 시공간적 강우분포 재현성 비교평가 (Comparative Evaluation of Reproducibility for Spatio-temporal Rainfall Distribution Downscaled Using Different Statistical Methods)

  • 정임국;황세운;조재필
    • 한국농공학회논문집
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    • 제65권1호
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    • pp.1-13
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    • 2023
  • Various techniques for bias correction and statistical downscaling have been developed to overcome the limitations related to the spatial and temporal resolution and error of climate change scenario data required in various applied research fields including agriculture and water resources. In this study, the characteristics of three different statistical dowscaling methods (i.e., SQM, SDQDM, and BCSA) provided by AIMS were summarized, and climate change scenarios produced by applying each method were comparatively evaluated. In order to compare the average rainfall characteristics of the past period, an index representing the average rainfall characteristics was used, and the reproducibility of extreme weather conditions was evaluated through the abnormal climate-related index. The reproducibility comparison of spatial distribution and variability was compared through variogram and pattern identification of spatial distribution using the average value of the index of the past period. For temporal reproducibility comparison, the raw data and each detailing technique were compared using the transition probability. The results of the study are presented by quantitatively evaluating the strengths and weaknesses of each method. Through comparison of statistical techniques, we expect that the strengths and weaknesses of each detailing technique can be represented, and the most appropriate statistical detailing technique can be advised for the relevant research.

Formation Mechanism Analysis and Detection of Charged Particles in an Aero-engine Gas Path

  • Wen, Zhenhua;Hou, Junxing;Jiang, ZhiQiang
    • International Journal of Aeronautical and Space Sciences
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    • 제16권2호
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    • pp.247-253
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    • 2015
  • The components of an aero-engine gas path cannot be monitored in a timely way due to a lack of real-time monitoring technologies. As an attempt to address this problem, we have conducted research on a condition monitoring technology based on the charging characteristics of particles in an aero-engine gas path, and emphatically analyze the formation of particles in an aero-engine gas path, the charging mechanism of carbon particles and the factors that influence the charge quantity and polarity. The verification experiments are performed on the simulated experiment platform and a turbo-shaft engine test bench. The results show the carbon particles' carry charge, and an obvious change in the total electrostatic charge level in the aero-engine gas path due to the increased carbon particles produced by burning or abnormal metal particles; the charge number is related to the size of particles, and the bigger carbon particles carry a negative charge and metal particles carry a positive charge; the change in engine power can lead to an obvious change in the level of electrostatic charge in the gas path, and the change in electrostatic charge results from the extra carbon particles formed in the rich-oil burning process. The research provides a reference for establishing the baseline of electrostatic charge while the engine runs on different power. The study also demonstrates the validity of the electrostatic monitoring technology and establishes a base for developing the application of electrostatic monitoring technology in aero-engines.

테이핑 요법으로 호전된 요통환자의 요추전만도 변화 1례 (Change of Lumbar Lordotic angle by Taping Therapy on Low Back Pain Patient with Lumbar Hyperlordosis ; A Case Report)

  • 윤유석;이종수;문상현
    • 대한추나의학회지
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    • 제4권1호
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    • pp.157-165
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    • 2003
  • Low back pain (LBP) is a significant in today's society, with lifetime include factors associated with LBP ar reporter. Among the causes, aberration of posture may play a role in the development of LBP. Many investigators have assessed the curvature of spine in standing posture. But LBP is associated with Lumber Hyperlordosis of Hyperlordosis is controversial Subjects: In conservative treatment(acupuncture, herb med, manipulation & TENS. exercise, potural correction) for a 40 years old woman who had low back pain(V AS) be caused by decrease lumbar lordotic angie. Objectives: The object is change of lumbar lordotic angle of a 40 years old woman who had low back pain with Lumbar hyperlordosis, In conservative treatment. Method: In conservative treatment, We added taping therapy(mechanical correction taping of Kinesio Taping) about Lumbar Lordosis. Conclusion: We experienced a 40 years old woman who had love pack pain with Lumbar hyperlordosis. In conservative treatment, Her pain was Improved by additional taping therapy In company with decrease of Lumbar Lordosis. 1. abnormal spinal curvature, specially lumbar hyperlordosis act on induction & perpetuation agent for low back pain 2. In a patient had low back pain with lumbar hyperlordosis, change of lumbar lordotic angle is of utility value for the effect of treatment and assessment of prognosis. 3. pain control is more relative with change of lumbosacral angle than lumbar lordotic angle, in patient had low back pain with lumbar hyperlordosis. 4. mechanical taping therapy with elastic adhesive tape is effective for patient had low back pain with lumbar hyperlordosis

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한약 사용 후 흡연자에서 폐기능 향상과 삶의 질 개선 (Improving Lung Function and Quality of Life in Smokers after Taking Herbal Medicine)

  • 고흥;김기태;신선미;이형권;문주호;박유진
    • 동의생리병리학회지
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    • 제27권1호
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    • pp.130-135
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    • 2013
  • We investigated the lung function change and quality of life in smokers after taking herbal medicine. The patients were divided into two groups(smoking and non-smoking). We measured lung function change by VRI and quality of life by BDI and Fatigue Scale Score before and after herbal medicine intake. And we examined changes of nicotine dependence, total smoking amount, tobacco flavor in smoking group. The VRI energy bar could not represent the change of the lung function in smoking group and non-smoking group. And there was no change of lung function by VRI in two group patients before and after herb medication. But after taking herb medicine, the patients who have abnormal sound in VRI were improved. The herbal medicine does not affect to the amount of smoking, tobacco flavor, nicotine dependence in Smoking patients. Smoking group were higher than non-smokers in BDI score and Fatigue Scale score. Smoking group were more improved than the non-smokers in BDI and Fatigue Scale Score after taking herbal medicine.

기능성 발보조기 착용 전후의 시상면의 편평족 발목각도 변화에 관한 연구 (Study on Change of the Flatfoot's Ankle Angle in Sagittal plane before and after Wearing FFO)

  • 박광용;박승환
    • 대한의용생체공학회:의공학회지
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    • 제31권1호
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    • pp.67-73
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    • 2010
  • The foot performs an important function in supporting the body and keeping body balance. An abnormal walking habit breaks the balance of the human body as well as the normal function of the foot. The influence of a flatfoot(pes planus) occupies a considerable portion of the various causes resulting in the wrong walking habit. But, little studies has been done by the functional foot orthotics for the flat foot. The object of this study, therefore, is to propose a new approach method to reveal the effects of the improvement of the foot function by using orthotics. The essential point of this study is to measure and analyze the change of ankle angle in the sagittal plane for flat foot subjects wearing the orthotics. Before and after wearing the functional orthotics, the gait analysis of flat foot subjects was conducted in three experimental aspects : the change of ankle angle, the change of the total Ankle ROM and the difference of left & right ankle angle in the sagittal plane. 1. The average ankle angle differences of before-and-after wearing the orthotics have declined like this; left : $2.71^{\circ}$, right: $1.91^{\circ}$ (p<0.05). 2. Total ankle ROM also showed decrease in both sides while the left side's is rather slight; left : $0.57^{\circ}$, right : $2.07^{\circ}$ (p<0.05). 3. The difference of left and right ankle angle in the sagittal plane decreased by $0.71^{\circ}$ (p<0.05). In result, it is confirmed that the functional foot orthotics have a significant effect on mechanical movement of ankle joint for flat foot. it is expected that this paper will be further studied and improved as a practical estimation method in the research on the effect of foot-orthotics.

상변화 메모리 소자 동작 특성에 미치는 열처리 온도 효과 (Effect of Annealing Temperature on the Operation of Phase-Change Memory)

  • 이승윤;박영삼
    • 한국진공학회지
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    • 제19권2호
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    • pp.155-160
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    • 2010
  • 상변화 메모리 소자 제작 공정의 단위 스텝인 최종 열처리의 온도가 상변화 메모리 소자 특성에 미치는 영향을 고찰하였다. $Ge_2Sb_2Te_5$ (GST) 박막을 활성 물질로 하는 기공(pore) 구조의 단위 상변화 메모리 소자를 제작하고, $160^{\circ}C$에서 $300^{\circ}C$까지의 온도 범위에서 최종 열처리를 실시하였다. 상변화 메모리 소자의 SET 저항에서 RESET 저항으로의 셀 저항 변화 양상은 최종 열처리 온도에 따라 큰 차이를 나타내었다. 정상적인 상변화 메모리 동작 특성을 얻을 수 있는 임계 열처리 온도가 존재하며, 열처리 온도가 그 온도에 비해 상대적으로 높거나 낮은 경우에는 소자가 오동작하거나 불안정하게 동작하는 것을 확인하였다. 이러한 열처리 온도의 효과는 열에너지에 따른 상부전극-GST 박막-발열층 다층 구조의 열적 안정성과 밀접한 관련이 있는 것으로 보인다.

농업기반시설물 양·배수장의 성능저하 요인분석 및 성능평가 모델 개발 (Development of Evaluation Model of Pumping and Drainage Station Using Performance Degradation Factors)

  • 이종혁;이상익;정영준;이제명;윤성수;박진선;이병준;이준구;최원
    • 한국농공학회논문집
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    • 제61권4호
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    • pp.75-86
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    • 2019
  • Recently, natural disasters due to abnormal climates are frequently outbreaking, and there is rapid increase of damage to aged agricultural infrastructure. As agricultural infrastructure facilities are in contact with water throughout the year and the number of them is significant, it is important to build a maintenance management system. Especially, the current maintenance management system of pumping and drainage stations among the agricultural facilities has the limit of lack of objectivity and management personnel. The purpose of this study is to develop a performance evaluation model using the factors related to performance degradation of pumping and drainage facilities and to predict the performance of the facilities in response to climate change. In this study, we focused on the pumping and drainage stations belonging to each climatic zone separated by the Korea geographical climatic classification system. The performance evaluation model was developed using three different statistical models of POLS, RE, and LASSO. As the result of analysis of statistical models, LASSO was selected for the performance evaluation model as it solved the multicollinearity problem between variables, and showed the smallest MSE. To predict the performance degradation due to climate change, the climate change response variables were classified into three categories: climate exposure, sensitivity, and adaptive capacity. The performance degradation prediction was performed at each facility using the developed performance evaluation model and the climate change response variables.