• Journal of Environmental Science International
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• v.23 no.11
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• pp.1827-1833
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• 2014

This study has been carried out to present the valuation system of soil carbon sequestration potentials of soil in accordance with the new climate change scenarios(RCP). For that, by analyzing variation of soil carbon of the each type of agricultural land use, it aims to develop technology to increase the amount of carbon emissions and sequestration. Among the factors which affects the estimation of determining the soil carbon model and influence power after the measurement on soil organic carbon, under the center of a causal relationship between the explanatory variables this study were investigated. Chemical fertilizers (NPK) decreased with increasing the amount of soil organic carbon and as with the first experimental results, when cultivating rice than pepper, the fact that soil organic carbon content increased has been found out. The higher the carbon dioxide concentration, the higher the amount of organic carbon in the soil and this result is reliable under a 10% significance level. On the other hand, soil organic carbon, humus carbon and hot water extractable carbon has been found out that was not affected the soils depth, sames as the result of the first year. The higher concentration of carbon dioxide, the higher carbon content of humus and hot water extractable carbon content. According to IPCC 2006 Guidelines and the new climate change scenario RCP 4.5 and the measurement results of the total amount of soil organic carbon to the crops due to abnormal climate weather, 1% increase in atmospheric carbon dioxide concentration was found to be small when compared to the growing rate of increasing 0.01058% of organic carbon in the soil.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.1
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• pp.135-143
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• 2014

This study classified abnormal sea surface temperature changes of the central pacific region according to three evolution patterns. Focusing on typhoons that affect the Korean Peninsula, the research analyzed typhoon's occurrence spot and track, change in the central pressure characteristics, and the characteristics of change in typhoon precipitation and the number of occurrences of heavy rainfall in the Nakdong River Basin. As a result of analysis, in case of prolonged-decaying years and symmetric-decaying years, typhoon-related summer rainfall and heavy rainy days appeared to be higher than long-term average. But in case of abrupt-decaying years, the pattern of general decrease appeared. This is because typhoon's occurrence spot is located comparatively near the Korean peninsula, typhoon's central pressure is high, and typhoon's route generally moves to Japan. As the outcome, this study is expected to reduce flood damage through analyzing the characteristics of typhoon's activity according to CP El Ni$\tilde{n}$o evolution patterns and the characteristics of local typhoon rainfall. In addition, it is expected to provide useful information for establishing adaptation and mitigation to climate change.

• The Korean Journal of Pharmacology
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• v.32 no.3
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• pp.425-431
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• 1996

Human neutrophil elastases (HNElastase, EC 3.4.21.37), a causative factor of inflammatory diseases, are regulated by plasma proteinase inhibitors, alpha-proteinase inhibitor and ${\alpha}_2-macroglobulin$. Under certain pathological conditions, however, released enzymes or abnormal function of inhibitors may cause various inflammatory disease. NSAIDs have been clinically applied for treatment of inflammatory diseases. Inhibition of cyclooxygenase is a known mechanism of action of NSAIDs in the treatment of inflammatory disease. In in vitro experiments, HNElastase was inhibited by naproxen, phenylbutazone, and oxyphenbutazone, but ibuprofen, ketoprofen, aspirin, salicylic acid, and tolmetin did not inhibit elastase. HNElastase was also inhibited by chelating agents, EDTA & EGTA, and tetracyclines. Removal of divalent metal ions by EDTA caused inhibition of elastase, and reconstitution of the metal ions recovered the enzyme activity to a certain level. Frequencies and contours in the Raman spectra of various conditions of human neutrophil elastase undergo drastic changes upon partial removal and/or reconstitution of calcium and zinc ions. The metal ion content dependent activities and change of the contour of the Raman spectrogram suggest us that the mechanism of action of a chelator or chelator-like agents on neutrophil elastase may be related to the conformational change at/or near the active site, especially -C=O radical or -COOH radical.

• Journal of Environmental Impact Assessment
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• v.27 no.4
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• pp.335-344
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• 2018

As the damage caused by the abnormal climate due to climate change is increasing, the interest in resilience is increasing as a countermeasure to this. In this study, the resilience of Suwon city was examined and the plan to improve the resilience were derived against climate impacts such as drought, heatwave, and heavy rain. Urban resilience is divided into social resilience (e.g. vulnerable groups, access to health services, and training of human resources), economic resilience (e.g. housing stability, employment stability, income equality, and economic diversity), urban infrastructure resilience (e.g.residential vulnerability, capacity to accommodate victims, and sewage systems), and ecological resilience (e.g. protection resources, sustainability, and risk exposure). The study evaluated the urban resilience according to the selected indicators in local level. In this study, the planning elements to increase the resilience in the urban dimension were derived and suggested the applicability. To be a resilient city, the concept and value of resilience should be included in urban policy and planning. It is critical to monitor and evaluate the process made by the actions in order to continuously adjust the plans.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.464-473
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• 2016

The air temperatures of the coast and inland are rising due to an increase in carbon dioxide emissions and abnormal climate phenomena caused by global warming, El Nino, La Nina and so on. The sea levels of the Earth are rising by approximately 2.0 mm per year (global average value) due to the thermal expansion of sea water, melting of glaciers and other causes by global warming. On the other hand, when it comes to designing a hydraulic structure or coastal hydraulic structure, the standard of the design water level is decided by analyzing four largeness tide values and a harmonic constant with the observed tidal water level or simulating numerical model. Therefore, the design tidal water level needs to consider an increasing speed of the seawater level, which corresponds to the design frequency. In the present study, the observed tidal water levels targeting 46 tidal stations operated by the Korea Hydrographic and Oceanographic Administration (KHOA) from the beginning of observations to 2015 per hour were collected. The variation of the monthly and yearly and increasing ratio were performed and divided into 7 seas, such as east and west part of the Southern Sea, south part and middle of the East Sea, south part and middle of the Western Sea, and Jeju Sea. The current study could be used to determine the cause of local seawater rises and reflect the design tidal water level as basic data.

• Journal of Korea Water Resources Association
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• v.32 no.6
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• pp.617-625
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• 1999

Global warming has begun since the industrial revolution and it is getting worse recently. Even though the increase of greenhouse gases such as $CO_2$ is thought to be the main cause for global warming, its impact on global climate has not been revealed clearly in rather quantitative manners. However, researches using General Circulation Models(GCMs) has shown the accumulation of greenhouse gases increases the global mean temperature, which in turn impacts on the global water circulation pattern. This changes in global water circulation pattern result in abnormal and more frequent meteorological events such as severe floods and droughts, generally more severe than the normal ones, which are now common around the world and is referred as a indirect proof of global warming. Korean peninsula also cannot be an exception and have had several extremes recently. The main objective of this research is to analyze the impact of global warming on the change of flood and drought frequency. Based on the assumption that now is a point in a continuously changing climate due to global warming, we analyzed the observed daily rainfall data to find out how the increase of annual rainfall amount affects the distribution of daily rainfall. Obviously, the more the annual rainfall depth, the more frequency of much daily rainfall, and vice versa. However, the analysis of the 17 points data of Keum river basin in Korea shows that especially the number of days of under 10mm or over 50mm daily rainfall depth is highly correlated with the amount of annual rainfall depth, not the number of dry days with their correlation coefficients quite high around 0.8 to 0.9.

• Journal of Veterinary Clinics
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• v.28 no.5
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• pp.473-478
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• 2011

The study evaluated the antioxidant effects of ascorbic acid (AA) against oxidative stress during laparotomy in dogs under general anesthesia using isoflurane. Twelve dogs were randomly assigned to either the ascorbic acid group (AAG) or the sham group (SG). AAG received intravenous dosage of 100 mg/animal of standard AA 10 minutes before anesthesia. Plasma levels of cortisol, glucose, total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) were measured. Cortisol level increased significantly with time in both groups (p < 0.05). The change of glucose levels was not significantly different between both groups. TOS and OSI increased significantly with time in the SG (p < 0.05), whereas it did not significantly change with time in the AAG. The TOS and OSI of the AAG were significantly lower than in the SG (p < 0.05). However, TAS did not significantly change between both groups. The results suggest that the decrease of TOS in the AAG might be related to the conversion of antioxidants to oxidants. The decrease of OSI indicates that the decrease of reactive oxygen species (i.e., oxidative stress) produced at the site of injury is able to decrease surgical side effects of abnormal blood circulation, organ failure, and inflammation. Therefore, AA can be used to protect a surgical patient from oxidative stress in canine laparotomy.

• Journal of Korea Water Resources Association
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• v.55 no.10
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• pp.749-759
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• 2022

The paradigm of water cycle management in the watershed is changing due to the increase in abnormal climate phenomena caused by climate change and the increase in impervious area due to urbanization. Research is continuously underway based on Low Impact Development technology that can suppress water cycle distortion. In this study, factors that can reflect water cycle distortion were selected before applying LID, and the PSR index for each 148 watershed was calculated for the the Nakdonggang River basin. As of 1975, the PSR index is calculated by calculating the pressure index P, which represents the rate of change in impervious surface area to 2019, the phenomenon index S, which represents the rate of change in water cycle for each subwatershed, and the Low Impact Development area countermeasure index R. The lower PSR index value, the higher the priority management watershed, and the water cycle recovery priority management watershed was calculated in the order of 1, 2, 87, 90, 91, and 147. It is expected that the efficient application of low-impact development factors in accordance with the order of priority management of water cycle by subwatershed in the large area will contribute to the recovery of water cycle distortion.

• Journal of Korea Water Resources Association
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• v.55 no.spc1
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• pp.1211-1222
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• 2022

Abnormal condition inevitably occurs during operation of water distribution system (WDS) and requires the isolation of certain areas using isolation valves. In general, the determination of the optimal location of isolation valves considered minimization of hydraulic failures as isolation of certain areas causes a change in hydraulic states (e.g., flow direction, velocity, pressure, etc.). Water quality failure can also be induced by changes in hydraulics, which have not been considered for isolation valve system design. Therefore, this study proposes a new isolation valve system design methodology to prevent unexpected water quality failure events. The new methodology considers flow direction change ratio (FDCR), which accounts for flow direction changes after isolation of the area, as a constraint while reliability is used as the objective function. The optimal design model has been applied to a synthetic grid network and the results are compared with the traditional design approach. Results show that considering FDCR can eliminate flow direction changes while average pressure and coefficient of variation of pressure, velocity, and hydraulic geodesic index (HGI) outperform compared to the traditional design approach. The proposed methodology is expected to be a useful approach to minimizing unexpected consequences by traditional design approaches.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.4
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• pp.40-48
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• 2023

Objectives: The purpose of this study is to investigate safety of postpartum herbal medicine by assessing the effect of taking herbal medicine of postpartum period on liver function. Methods: A retrospective chart review was conducted on 167 mothers who underwent liver function tests (LFT) within 3 months before and after childbirth among mothers who gave birth at ○○ Hospital between January 1, 2016 and May 31, 2018. Mothers with abnormally elevated LFT during pregnancy were excluded. Among 167 women, 6 women are herbal-medicine-group took herbal medicine for 5-6 weeks during postpartum period, and 161 patients are general -group who did not take herbal medicine. LFT Variation of Subjects before and after childbirth were compared between the two groups. And subjects who had elevated liver levels above the normal range after delivery were classified separately, the characteristics and causes of changes in liver levels were analyzed, and the presence or absence of drug-induced liver damage was confirmed. Results: Among a total of 167 subjects, there were 5 women in the herbal-medicine-group and 150 women in the general-group who had changes in liver values within the normal range after childbirth. Aspartate transaminase (AST) change before and after childbirth in the herbal-medicine-group was 3.40±1.82, and AST change in the general-group was 2.92±8.59, showing no significant difference between the two groups (p=0.901). Increase of Alanine transaminase (ALT) before and after childbirth in the herbal-medicine-group was 5.60±3.65, and ALT change in the general-group was 8.01±11.81, showing no significant difference between the two groups (p=0.651). There were 12 subjects who had elevated AST, ALT above the normal range after delivery, including 1 in the herbal-medicine-group and 11 in the normal mothers group. Valuation of 1 Subject of the herbal-medicine-group before and after delivery was 17 IU/L of AST and 52 IU/L of ALT. Because results of AST, ALT is under the standard to diagnose to liver damage, she was observed without any treatment. However the cause of AST, ALT elevation was not found in the chart, she was receiving treatment for diabetes and hyperlipidemia. The general-group had an average increase of AST 35.64±22.67 IU/L and ALT 53.00±26.80 IU/L. As a result of analyzing the cause, there were direct causes such as autoimmune hepatitis, chronic hepatitis B, and acute pyelonephritis. Abnormal elevations in liver levels were also found in mothers with hypothyroidism, diabetes, and fever of unknown cause, although they were not direct causes. Conclusions: To investigate the safety of taking herbal medicines, we assess the variation in AST and ALT within 3 months before and after delivery in the herbal-medicine-group and general-group. There was no significant difference between two groups.