• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.1
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• pp.464-469
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• 2019

A remote monitoring panel and control system was developed to control various valves and access control chambers, including gas shutoff valves used in CBR(Chemical, Biological and Radiological) facilities. The remote monitoring panel consisted of a main panel installed in the NBC (Nuclear, Biological and Chemical) control room and auxiliary panel installed in the clean room, and the size was divided into pure control and control including CCTV. This system can be monitored and controlled remotely according to the situation where an explosion door and gas barrier door can occur during war and during normal times. This system is divided into normal mode and war mode. In particular, it periodically senses the operation status of various valves, sensors, and filters in the CBR facilities to determine if each apparatus and equipment is in normal operation, and remotely alerts situation workers when repair or replacement is necessary. Damage due to the abnormal operation of each device in the situation can be prevented. This enables control of the blower, supply and exhaust damper, emergency generator, and coolant pump according to the state of shutoff valve and positive pressure valve in the occurrence of NBC, and prevents damage caused by abrupt inflow of conventional weapons and nuclear explosions.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.3
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• pp.351-359
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• 2019

Neurocognitive testing commonly uses the MMSE (Mini-Mental State Examination) to evaluate the overall cognitive function of patients at outpatient clinics, but the MMSE has recently been extensively used in the SNSB II (Seoul Neuropsychological Screening Battery II) for making diagnoses. We retrospectively investigated the results of routine neurocognitive tests and the results of the blood tests of 120 elderly patients who had been referred to a South Central Medical Center from 2017 to 2018 and who had been examined at a public health center. These subjects' space-time capability was high on the sub-region of the global deterioration scale (GDS). GDS showed a significant increase as the Na decreased on the electrolyte analysis. The subjects' concentration, their language-based orientation for space and time, their memory, and their scores for the frontal lobe function on GDS showed statistically significant reductions (P<0.001) For the normal and abnormal groups according to the ALT and creatinine levels, the frontal/execute function areas showed statistically significant differences (P<0.001) as well as negative correlation between GDS and ALT (P<0.01). In conclusion, this study provides basic information to develop test items that are important for patient screening and diagnosis, and several routine blood chemistry factors provide basic information for diagnosing and assessing the status and progress of cognitively impaired patients.

• Journal of Convergence for Information Technology
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• v.9 no.9
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• pp.13-19
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• 2019

This paper analyzed the SCMS and pilot policy, which is pursued by the U.S. government in connected vehicles. SCMS ensures authentication, integrity, privacy and interoperability. The SCMS Support Committee of U.S. government has established the National Unit SCMS and is responsible for system-wide control. Of course, it introduces security policy, procedures and training programs making. In this paper, the need for SCMS to be applied to C-ITS was discussed. The structure of the SCMS was analyzed and the U.S. government's filot policy for connected vehicles was discussed. The discussion of the need for SCMS highlighted the importance of the role and responsibilities of SCMS between vehicles and vehicles. The security certificate management system looked at the structure and analyzed the type of certificate used in the vehicle or road side unit (RSU). The functions and characteristics of the certificates were reviewed. In addition, the functions of basic safety messages were analyzed with consideration of the detection and warning functions of abnormal behavior in SCMS. Finally, the status of the pilot project for connected vehicles currently being pursued by the U.S. government was analyzed. In addition to the environment used for the test, the relevant messages were also discussed. We also looked at some of the issues that arise in the course of the pilot project.

• Journal of Navigation and Port Research
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• v.46 no.6
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• pp.562-569
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• 2022

The alarm monitoring technology applied to existing operating ships manages data items such as temperature and pressure with AMS (Alarm Monitoring System) and provides an alarm to the crew should these sensing data exceed the normal level range. In addition, the maintenance of existing ships follows the Planned Maintenance System (PMS). whereby the sensing data measured from the equipment is monitored and if it surpasses the set range, maintenance is performed through an alarm, or the corresponding part is replaced in advance after being used for a certain period of time regardless of whether the target device has a malfunction or not. To secure the reliability and operational safety of ship engine operation, it is necessary to enable advanced diagnosis and prediction based on real-time condition monitoring data. To do so, comprehensive measurement of actual ship data, creation of a database, and implementation of a condition diagnosis monitoring system for condition-based predictive maintenance of auxiliary equipment and piping must take place. Furthermore, the system should enable management of auxiliary equipment and piping status information based on a responsive web, and be optimized for screen and resolution so that it can be accessed and used by various mobile devices such as smartphones as well as for viewing on a PC on board. This update cost is low, and the management method is easy. In this paper, we propose CBM (Condition Based Management) technology, for autonomous ships. This core technology is used to identify abnormal phenomena through state diagnosis and monitoring of pumps and purifiers among ship auxiliary equipment, and seawater and steam pipes among pipes. It is intended to provide performance diagnosis and failure prediction of ship auxiliary equipment and piping for convergence analysis, and to support preventive maintenance decision-making.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.6
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• pp.874-881
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• 2022

Until 2016, before discussions on the restoration of brackish water of the Nakdong River Estuary started in earnest, the downstream water level was predicted using the data of existing tide level observatories (Busan and Gadeokdo) several kilometers away from the estuary. However, it was not easy to carry out the prediction due to the dif erence in tide level and phase. Therefore, this study was conducted to estimate tide prediction more accurately through tidal harmonic analysis using the measured water level affected by the tides in the offshore waters adjacent to the Nakdong River Estuary. As a research method, the storage status of observation data according to the period and abnormal data were checked at 10-minute intervals in the offshore sea area near the Nakdong River Estuary bank, and the observed and predicted tides were measured using TASK2000 (Tidal Analysis Software Kit) Package, a tidal harmonic analysis program. Regression analysis based on one-to-one comparison showed that the correlation between the two components was high correlation coef icient 0.9334. In predicting the tides for the current year, if possible, more accurate data can be obtained by harmonically analyzing one-year tide observation data from the previous year and performing tide prediction using the obtained harmonic constant. Based on this method, the predicted tide for 2022 was generated and it is being used in the calculation of seawater inflow for the restoration of brackish water of the Nakdong River Estuary.

• BMB Reports
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• v.55 no.6
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• pp.275-280
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• 2022

The treatment of atopic dermatitis (AD) is challenging due to its complex etiology. From epidermal disruption to chronic inflammation, various cells and inflammatory pathways contribute to the progression of AD. As with immunosuppressants, general inhibition of inflammatory pathways can be effective, but this approach is not suitable for long-term treatment due to its side effects. This study aimed to identify a plant extract (PE) with anti-inflammatory effects on multiple cell types involved in AD development and provide relevant mechanistic evidence. Degranulation was measured in RBL-2H3 cells to screen 30 PEs native to South Korea. To investigate the anti-inflammatory effects of Parasenecio auriculatus var. matsumurana Nakai extract (PAE) in AD, production of cytokines and nitric oxide, activation status of FcεRI and TLR4 signaling, cell-cell junction, and cell viability were evaluated using qRT-PCR, western blotting, confocal microscopy, Griess system, and an MTT assay in RBL-2H3, HEK293, RAW264.7, and HaCaT cells. For in vivo experiments, a DNCBinduced AD mouse model was constructed, and hematoxylin and eosin, periodic acid-Schiff, toluidine blue, and F4/80-staining were performed. The chemical constituents of PAE were analyzed by HPLC-MS. By measuring the anti-degranulation effects of 30 PEs in RBL-2H3 cells, we found that Paeonia lactiflora Pall., PA, and Rehmannia glutinosa (Gaertn.) Libosch. ex Steud. show an inhibitory activity of more than 50%. Of these, PAE most dramatically and consistently suppressed cytokine expression, including IL-4, IL-9, IL-13, and TNF-α. PAE potently inhibited FcεRI signaling, which mechanistically supports its basophil-stabilizing effects, and PAE downregulated cytokines and NO production in macrophages via perturbation of toll-like receptor signaling. Moreover, PAE suppressed cytokine production in keratinocytes and upregulated the expression of tight junction molecules ZO-1 and occludin. In a DNCB-induced AD mouse model, the topical application of PAE significantly improved atopic index scores, immune cell infiltration, cytokine expression, abnormal activation of signaling molecules in FcεRI and TLR signaling, and damaged skin structure compared with dexamethasone. The anti-inflammatory effect of PAE was mainly due to integerrimine. Our findings suggest that PAE could potently inhibit multi-inflammatory cells involved in AD development, synergistically block the propagation of inflammatory responses, and thus alleviate AD symptoms.

• Journal of Pharmacopuncture
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• v.26 no.1
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• pp.27-37
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• 2023

Objectives: Moroccan Arbutus unedo is an essential medicinal plant; however, little is known about the biological properties of its leaves mentioned in Moroccan traditional medicine. Methods: Various standard experiments were performed to evaluate the phytochemical, antidiabetic, antioxidant, antibacterial, and acute and sub-chronic toxicity characteristics of A. unedo leaves. Results: Phytochemical screening led to the identification of several phytochemical classes, including tannins, flavonoids, terpenoids, and anthraquinones, with high concentrations of polyphenols (31.83 ± 0.29 mg GAEs/g extract) and flavonoids (16.66 ± 1.47 mg REs/g extract). Further, the mineral analysis revealed high levels of calcium and potassium. A. unedo extract demonstrated significant antioxidant and anti-diabetic activities by inhibiting α-amylase (1.350 ± 0.32 g/mL) and α-glucosidase (0.099 ± 1.21 g/mL) compared to the reference drug Acarbose. Also, the methanolic extract of the plant exhibited significantly higher antibacterial activity than the aqueous extract. Precisely, three of the four examined bacterial strains exhibited substantial susceptibility to the methanolic extract . Minimum bactericidal concentration (MBC)/minimum inhibitory concentration (MIC) values indicated that A. unedo harbor abundant bactericidal compounds. For toxicological studies, mice were administered with A. unedo aqueous extract at single doses of 2,000 and 5,000 mg/kg. They did not exhibit significant abnormal behavior, toxic symptoms, or death during the 14-day acute toxicity test and the 90-day sub-chronic toxicity test periods. The general behavior, body weight, and hematological and biochemical status of the rats were assessed, revealing no toxicological symptoms or clinically significant changes in biological markers observed in the mice models, except hypoglycemia, after 90 days of daily dose administration. Conclusion: The study highlighted several biological advantages of A. unedo leaves without toxic effects in short-term application. Our findings suggest that conducting more comprehensive and extensive in vivo investigations is of utmost importance to identify molecules that can be formulated into pharmaceuticals in the future.

• Korean Journal of Remote Sensing
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• v.39 no.5_2
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• pp.755-770
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• 2023

Due to recent severe climate change, abnormal weather phenomena, and other factors, the frequency and magnitude of natural disasters are increasing. The need for disaster management using artificial satellites is growing, especially during large-scale disasters due to time and economic constraints. In this study, we have summarized the current status of next-generation medium-sized satellites and microsatellites in operation and under development, as well as trends in satellite imagery analysis techniques using a large volume of satellite imagery driven by the advancement of the space industry. Furthermore, by utilizing satellite imagery, particularly focusing on recent major disasters such as floods, landslides, droughts, and wildfires, we have confirmed how satellite imagery can be employed for damage analysis, thereby establishing its potential for disaster management. Through this study, we have presented satellite development and operational statuses, recent trends in satellite imagery analysis technology, and proposed disaster response strategies that utilize various types of satellite imagery. It was observed that during the stages of disaster progression, the utilization of satellite imagery is more prominent in the response and recovery stages than in the prevention and preparedness stages. In the future, with the availability of diverse imagery, we plan to research the fusion of cutting-edge technologies like artificial intelligence and deep learning, and their applicability for effective disaster management.

• Korean Journal of Radiology
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• v.24 no.4
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• pp.274-283
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• 2023

Objective: To compare the outcomes of digital breast tomosynthesis (DBT) screening combined with ultrasound (US) with those of digital mammography (DM) combined with US in women with dense breasts. Materials and Methods: A retrospective database search identified consecutive asymptomatic women with dense breasts who underwent breast cancer screening with DBT or DM and whole-breast US simultaneously between June 2016 and July 2019. Women who underwent DBT + US (DBT cohort) and DM + US (DM cohort) were matched using 1:2 ratio according to mammographic density, age, menopausal status, hormone replacement therapy, and a family history of breast cancer. The cancer detection rate (CDR) per 1000 screening examinations, abnormal interpretation rate (AIR), sensitivity, and specificity were compared. Results: A total of 863 women in the DBT cohort were matched with 1726 women in the DM cohort (median age, 53 years; interquartile range, 40-78 years) and 26 breast cancers (9 in the DBT cohort and 17 in the DM cohort) were identified. The DBT and DM cohorts showed comparable CDR (10.4 [9 of 863; 95% confidence interval {CI}: 4.8-19.7] vs. 9.8 [17 of 1726; 95% CI: 5.7-15.7] per 1000 examinations, respectively; P = 0.889). DBT cohort showed a higher AIR than the DM cohort (31.6% [273 of 863; 95% CI: 28.5%-34.9%] vs. 22.4% [387 of 1726; 95% CI: 20.5%-24.5%]; P < 0.001). The sensitivity for both cohorts was 100%. In women with negative findings on DBT or DM, supplemental US yielded similar CDRs in both DBT and DM cohorts (4.0 vs. 3.3 per 1000 examinations, respectively; P = 0.803) and higher AIR in the DBT cohort (24.8% [188 of 758; 95% CI: 21.8%-28.0%] vs. 16.9% [257 of 1516; 95% CI: 15.1%-18.9%; P < 0.001). Conclusion: DBT screening combined with US showed comparable CDR but lower specificity than DM screening combined with US in women with dense breasts.

• Journal of the Korean Society of School Health
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• v.14 no.1
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• pp.131-143
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• 2001

The primary aim of this dissertation is to contribute to the improvement of methods in physical examination by providing quality information for the current school system and advice for improving status. Present status, controversial points and possible remedies in physical examination were analyzed on a frequency and percentage basis. An $x^2$-test was used to verify the statistics between the results from the examination and each variable. In case of multiple categories of variables, an $x^2$ cs was adopted. Chronological data as well as both total and sampling physical examination data verified the statistics using an $x^2$-test. This thesis is based both on the data from middle school health care specialists in Gyunggi Province and on the analysis of physical examinations reported from local schools to the municipal education agency from 1997 to 1999. The results of the study are as follows: First, according to the survey, only 29.0% of the total schools had their school doctors examine all the students while most of the educational institutions failed to implement the whole process of physical examination on the list. It also turned out that the more students the schools have, the lower the rate of implementation of physical examination by school doctors(p=0.014). Second, the average time a school doctor spends for checkup turned out to be approximately 1.7 minutes per student This means that the quality of the physical examination is not guaranteed in the process. Third, 47.7% of those surveryed say that a dental examination was performed, each taking 21.24 seconds on average. In addition, it shows that some 31.5% wanted to have a task force team for dental checkups at the local health center. Given the fact that dental caries among students is progressively on the rise, the dental health centers that are now set up in some elementary schools should be expanded to cover the whole educational institution in order to raise awareness of the importance of dental care. Fourth, 48.5% of those surveyed say that a comprehensive physical examination should be adopted to promote the health of high schoolers. Since it takes a lot of public funds to implement a comprehensive method, it is essential to make sure that in-depth studies should be based on the frequency and methods of physical examination. Fifth, regarding such diseases among 3rd year middle school students in 1999, statistics shows that there was a slight difference in the prevalence rate of color blindness, and allergic diseases for male students ; and color blindness, hearing disturbance and allergic disease for female students. For those items, however, it is too little to say that there is a significant difference and accordingly it is assumed to be a problem of the measuring process. Sixth, the result of analysis on the sample physical examination and the total physical examination of the year 1999 shows as follows: For male students in the 3rd year of middle school, a slight difference appeared to those students in 11 items including eye problems and eye disease, otitis media, tonsillar hypertrophy, spinal shape, respiratory urinary allergic disease and other abnormal diseases(p<0.05). Particularly, the prevalence rate between students with and without disease was shown to be two times more in the following: eye problems, otitis media, tonsill hypertrophy, allergic diseases, etc. For female students in the 3rd year, prevalence rate showed little difference in 14 items(p<0.05). For items including eye problem, otitis media, tonsill hypertrophy, allergic disease, etc. it was shown that the rate was two times more between students with and without diseases. Physical examinations under the current school system are not producing any fundamental results for the health of the students. Methods and results are not trustworthy. Accordingly, a drastic overhaul of the current practices is needed in frequency, methods and items on the list in order to promote the health of the students. Cost-benefit studies as well as political considerations to ensure the development of efficient methods for physical examination are urgently needed at this moment.