• 한국전자파학회논문지
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• 제18권2호
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• pp.105-110
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• 2007

본 논문에서는 $6{\sim}18$ GHz의 넓은 대역에서 진폭 선형성을 얻기 위해, 인접 전송선-스터브 블록 간에 저항이 삽입된, 마이크로스트립형의 선형 진폭 등화기가 구현된다. 선형성과 반사 손실 특성을 만족하도록 저항과 스터브의 값들이 변화하며, 적합한 수치를 찾으면서 설계가 이뤄진다. 실험치는 본 구현 결과는 $6{\sim}18$ GHz에서 요구되는 약 9 dB의 선형도와 약 10 dB 이하의 반사 손실이 얻어지고, 설계 기법의 타당함을 보인다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3761-3768
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• 2013

Background: The Saudi population has experienced a sharp increase in colorectal and gastric cancer incidences within the last few years. The relationship between gene polymorphisms of xenobiotic metabolizing enzymes and colorectal cancer (CRC) incidence has not previously investigated among the Saudi population. The aim of the present study was to investigate contributions of CYP1A1, CYP2E1, and GSTM1 gene polymorphisms. Materials and Methods: Blood samples were collected from CRC patients and healthy controls and genotypes were determined by polymerase chain reaction restriction fragment length polymorphism and sequencing. Results and Conclusions: $CYP2E1^*6$ was not significantly associated with CRC development (odd ratio=1.29; confidence interval 0.68-2.45). A remarkable and statistically significant association was observed among patients with $CYP1Awt/^*2A$ (odd ratio=3.65; 95% confidence interval 1.39-9.57). The $GSTM1^*0/^*0$ genotype was found in 2% of CRC patients under investigation. The levels of CYP1A1, CYP2E1 and GSTM1 mRNA gene expression were found to be 4, 4.2 and 4.8 fold, respectively, by quantitative real time PCR. The results of the present case-control study show that the studied Saudi population resembles Caucasians with respect to the considered polymorphisms. Investigation of genetic risk factors and susceptibility gene polymorphisms in our Saudi population should be helpful for better understanding of CRC etiology.