• Title/Summary/Keyword: ASL

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Arterial Spin Labeling MRI for Quantitative Assessment of Cerebral Perfusion Before and After Cerebral Revascularization in Children with Moyamoya Disease

  • Ji Young Ha;Young Hun Choi;Seunghyun Lee;Yeon Jin Cho;Jung-Eun Cheon;In-One Kim;Woo Sun Kim
    • Korean Journal of Radiology
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    • v.20 no.6
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    • pp.985-996
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    • 2019
  • Objective: To determine the correlation between cerebral blood flow (CBF) on arterial spin labeling (ASL) MRI and the degree of postoperative revascularization assessed on digital subtraction angiography in children with moyamoya disease (MMD). Materials and Methods: Twenty-one children (9 boys and 12 girls; mean age, 8.4 ± 3.6 years; age range, 3-16 years) with MMD who underwent both pseudocontinuous ASL MRI at 1.5T and catheter angiography before and after superficial temporal artery encephaloduroarteriosynangiosis were included in this retrospective study. The degree of revascularization in the middle cerebral artery (MCA) territory was evaluated on external carotid angiography and was graded on a 3-point scale. On ASL CBF maps, regions of interest were manually drawn over the MCA territory of the operated side at the level of the centrum semi-ovale and over the cerebellum. The normalized CBF (nCBF) was calculated by dividing the CBF of the MCA territory by the CBF of the cerebellum. Changes in nCBFs were calculated by subtracting the preoperative nCBF values from the postoperative nCBF values. The correlation between nCBF changes measured with ASL and the revascularization grade from direct angiography was evaluated. Results: The nCBF value on the operated side increased after the operation (p = 0.001). The higher the degree of revascularization, the greater the nCBF change was: poor revascularization (grade 1), -0.043 ± 0.212; fair revascularization (grade 2), 0.345 ± 0.176; good revascularization (grade 3), 0.453 ± 0.182 (p = 0.005, Jockheere-Terpstra test). The interobserver agreement was excellent for the measured CBF values of the three readers (0.91-0.97). Conclusion: The nCBF values of the MCA territory obtained from ASL MRI increased after the revascularization procedure in children with MMD, and the degree of nCBF change showed a significant correlation with the degree of collateral formation evaluated via catheter angiography.

Clinical Usefulness of Arterial Spin Labeling Perfusion MR Imaging in Acute Ischemic Stroke (급성 허혈성 뇌경색 환자에서 동맥스핀표지 관류자기공명영상의 유용성)

  • Oh, Keun-Taek;Jung, Hong-Ryang;Lim, Cheong-Hwan;Cho, Young-Ki;Ha, Bon-Chul;Hong, Doung-Hee
    • Journal of radiological science and technology
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    • v.34 no.4
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    • pp.323-331
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    • 2011
  • We evaluated clinical usefulness of Arterial spin labeling perfusion MR imaging on the acute ischemic cerebral infarction patients through this study. We compared 22 patients who were done with DSC imaging and ASL imaging in admitted emergency room with acute ischemic cerebral infarction, with 36 normal comparison persons (DSC image on 21persons, ASL images on 15persons). Siemens Magnetom Verio 3.0T with 12 channel head coil was used for this study. DSC image obtained 4 maps(rCBV, rCBF, rMTT, TTP) through post-processing. For qualitative analysis we compared the area of lesion macro-diagonal with the size of diffusion weighted MR image for rMTT, TTP, rCBF, rCBV, ASL maps. For Quantitative analysis we analyzed significant correlations between less than 3 cm infarction group and normal comparison group using mean relative value of flowing image with Mann-Whitney U test. TTP(95.5%) and rCBF(95.5%) maps showed high recognition rate in qualitative analysis for >3cm infarction group. The rCBF and rCBV map tests were highly related with final stage stroke areas. Mean relative value of infarction group showed a significant correlations in quantitative analysis(p<0.05). As a conclusion, arterial spin labeling image showed high lesion recognition rate in the >3cm infarction group. Mean relative values in quantitative evaluation were used for reference data. If we do more sustainable researches, ASL image will be useful for an early diagnosis of cerebral infarction, determination of the range of ischemic pneumbra and effective treatments.

A Study on an Authorized Stockage List Selection Model (목표계획법을 이용한 사단급 ASL 선정 모형에 관한 연구)

  • 김충영;길계호
    • Journal of the military operations research society of Korea
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    • v.25 no.1
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    • pp.75-86
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    • 1999
  • The selection criteria of an Authorized Stockage List (ASL) in the Army is based on Army Regulation(AR)409. However, the current selection method of ASL is not considered in cost, weight and volume of repair parts. This paper is focused on developing for a new selection model taking account of cost, weight and volume of repair parts. Goal programming is utilized in order to consider weighted priorities. Different units of cost, and volume are normalized for using weighing value. Real data of a field division are applied to the model. Results of the new selection model are more reduced in cost, weight and volume than those of the previous method.

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Regulation of depth and composition of airway surface liquid

  • J. H. Widdicombe;S. J. Bastacky;D. X.Y. Wu;Lee, C. Y.
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.119-130
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    • 1996
  • We review the factors which regulate the depth and composition of the human airway surface liquid (ASL). These include secretion from airway submucosal glands, ion and fluid transport across the surface epithelium, goblet cell discharge, surface tension and transepithelial gradients in osmotic and hydrostatic pressure. We describe recent experiments in which we have used low temperature scanning electron microscopy of rapidly frozen specimens to detect changes in depth of ASL in response to submucosal gland stimulation. We also present preliminary data in which X-ray microanalysis of frozen specimens has been used to determine the elemental composition of ASL.

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Cerebrovascular Reservoir and Arterial Transit Time Changes Assessed by Acetazolamide-Challenged Multi-Phase Arterial Spin Labeling Perfusion MRI in Chronic Cerebrovascular Steno-Occlusive Disease (만성 뇌혈관 협착폐색증에서 아세타졸아미드 부하 다상 동맥스핀표지 자기공명관류영상으로 평가한 뇌혈류 예비능과 동맥 통과 시간의 변화)

  • Inpyeong Hwang;Chul-Ho Sohn;Keun-Hwa Jung;Eung Koo Yeon;Ji Ye Lee;Roh-Eul Yoo;Koung Mi Kang;Tae Jin Yun;Seung Hong Choi;Ji-hoon Kim
    • Journal of the Korean Society of Radiology
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    • v.82 no.3
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    • pp.626-637
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    • 2021
  • Purpose To explore cerebrovascular reservoir (CVR) and arterial transit time (ATT) changes using acetazolamide-challenged multi-phase arterial spin labeling (MP-ASL) perfusion-weighted MRI in chronic cerebrovascular steno-occlusive disease. Materials and Methods This retrospective study enrolled patients with chronic steno-occlusion who underwent acetazolamide-challenged MP-ASL between June 2019 and October 2020. Cerebral blood flow, CVR, basal ATT, and ATT changes associated with severe stenosis, total occlusion, and chronic infarction lesions were compared. Results There were 32 patients (5 with bilateral steno-occlusion) in our study sample. The CVR was significantly reduced during total occlusion compared with severe stenosis (26.2% ± 28.8% vs. 41.4% ± 34.1%, respectively, p = 0.004). The ATT changes were not significantly different (p = 0.717). The CVR was marginally lower in patients with chronic infarction (29.6% ± 39.1% vs. 38.9% ± 28.7%, respectively, p = 0.076). However, the ATT was less shortened in patients with chronic infarction (-54 ± 135 vs. -117 ± 128 ms, respectively, p = 0.013). Conclusion Acetazolamide-challenged MP-ASL provides an MRI-based CVR evaluation tool for chronic steno-occlusive disease.

Time Delay of Quench Phenomenon in Superconducting wire (초전도선재의 퀜치현상의 시간지연)

  • Oh, B.H.;Hong, I.S.;Jin, H.B.;Ryu, K.S.;Lee, S.H.
    • Proceedings of the KIEE Conference
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    • 1997.07a
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    • pp.270-272
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    • 1997
  • Superconducting wire is quenching as soon as transport current exceeded the critical current value. However transport current exceeded the critical current value, quench is not generated immediately. In this paper, the results of the theoretical study for time delay of quench phenomenon are described.

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The effects of labeling gap and susceptibility artifacts in pCASL perfusion MRI (pCASL 관류 영상에서 표지 간격과 자화감수성 인공물이 영상에 미치는 영향)

  • Kim, Seong-Hu
    • Journal of the Korean Society of Radiology
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    • v.9 no.4
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    • pp.213-217
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    • 2015
  • To report problems found in a patient who has implemented stent implantation and then conducted a perfusion MRI using ASL(Arterial Spin Labeling), in order to suggest a solution to them. The perfusion MRI was conducted, using pCASL among ASL methods. Data from pCASL(Pseudo Continuous Arterial Spin Labeling) was acquired together with the structural image simply by changing position(labeling gap 15 mm, 170 mm) of the labeling pulse to avoid stent. Data was processed through the ASLtbx. When perfusion MRI was acquired using pCASL, it showed that the position of the conventional labeling pulse (labeling gap 24 mm) was overlapped with that of stent, which made signal intensity in right brain tissue appear as if it were void. When the labeling pulse was positioned (labeling gap 15 mm) to avoid stent, high signal intensity images were acquired. In labeling pulse (labeling gap 170 mm), the signal intensity was more reduced due to relaxation before labeled blood arrived at the imaging slice. pCASL can be stably repeated measurements because it does not use a contrast agent. And it should be selected with the appropriate image acquisition parameters for the high quality image.

Randomized controlled clinical trial of oral health-related quality of life in patients wearing conventional and self-ligating brackets

  • Othman, Siti Adibah;Mansor, Noorhanizar;Saub, Roslan
    • The korean journal of orthodontics
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    • v.44 no.4
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    • pp.168-176
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    • 2014
  • Objective: The aim of this randomized controlled clinical trial was to compare oral health-related quality of life (OHRQoL) of patients treated with conventional, active self-ligating (ASL), and passive self-ligating (PSL) brackets in different therapeutic phases. Methods: Sixty patients (mean age 18.3 years; 29 males and 31 females) requiring orthodontic treatment were randomly and equally assigned to receive conventional (Victory Series), ASL (In-Ovation R), or PSL (Damon 3MX) brackets. OHRQoL was measured with a self-administered modified 16-item Malaysian version of the Oral Health Impact Profile for immediate (soon after the visit) and late (just before the subsequent visit) assessments of the bonding and activation phases. Data were analyzed with the Kruskal-Wallis and chi-square tests. Results: The PSL and ASL groups showed more immediate and late impacts in the bonding phase, respectively; the conventional group was affected in both the assessments. The first activation phase had similar impacts in the groups. After the second activation, the conventional group showed more immediate impacts, whereas the PSL and ASL groups had more late impacts. The commonly affected domains were "physical disability," "functional limitation," "physical pain," and "psychological discomfort." No significant differences in the prevalence and severity of immediate and late impacts on OHRQoL of the patients were noted in any therapeutic phase. Conclusions: No bracket system seems to ensure superior OHRQoL. This information could be useful for explaining the therapeutic phases, especially the initial one, and selecting the optimal bracket system based on the patient's preference.

Human hand gesture identification framework using SIFT and knowledge-level technique

  • Muhammad Haroon;Saud Altaf;Zia-ur- Rehman;Muhammad Waseem Soomro;Sofia Iqbal
    • ETRI Journal
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    • v.45 no.6
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    • pp.1022-1034
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    • 2023
  • In this study, the impact of varying lighting conditions on recognition and decision-making was considered. The luminosity approach was presented to increase gesture recognition performance under varied lighting. An efficient framework was proposed for sensor-based sign language gesture identification, including picture acquisition, preparing data, obtaining features, and recognition. The depth images were collected using multiple Microsoft Kinect devices, and data were acquired by varying resolutions to demonstrate the idea. A case study was designed to attain acceptable accuracy in gesture recognition under variant lighting. Using American Sign Language (ASL), the dataset was created and analyzed under various lighting conditions. In ASL-based images, significant feature points were selected using the scale-invariant feature transformation (SIFT). Finally, an artificial neural network (ANN) classified hand gestures using specified characteristics for validation. The suggested method was successful across a variety of illumination conditions and different image sizes. The total effectiveness of NN architecture was shown by the 97.6% recognition accuracy rate of 26 alphabets dataset with just a 2.4% error rate.