• 대한안전경영과학회지
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• 제15권2호
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• pp.217-221
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• 2013

I suggest a new method to determine the importance values of quality attributes which use the satisfaction index and dissatisfaction index of customer in Kano's model. A case study of TV set are solved by the proposed method and the result is compared with AHP pairwise comparisons and ASC(Average Satisfaction Coefficient). The results of the proposed method is similar with those of AHP pairwise comparisons and ASC. The proposed method is an effective tool to determine the importance values of quality attributes to supplement existing research's shortcomings.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.903-907
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• 2013

Primary screening by HPV DNA testing is an effective method for reducing cervical cancer and has proven more sensitive than cytology. To advance this approach, many molecular methods have been developed. Hybrid capture 2 provides semi-quantitative results in ratios of relative light units and positive cutoff values (RLU/PC). Twenty-five thousand and five patients were included in this study to analyze the correlation between the ratio of RLU/PC and stage of cervical dysplasia. The results show that the RLU/PC ratios ranged from 0-3500 while almost normal cases, ASC-US and ASC-H, had values below 200. Of those samples negative for cytology markers, 94.6% were normal and their RLU/PC ratios were less than 4. With an RLU/PC ratio greater than 4 and less than or equal to 300, the percentages in all age groups were normal 53.6%, LSIL 20.2%, ASC-US 17.2%, HSIL 6.13%, ASC-H 2.72%, and AGC 0.11%, respectively. In contrast, 64.0% of samples with a RLU/PC ratio greater than 300 and less than or equal to 3500 were LSIL. These results should contribute to cost effective cervical cancer management strategies. Further studies of associations with particular HPV genotypes would be useful to predict the risk of progression to cancer.

• 한국태양광발전학회지
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• 제2권2호
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• pp.36-43
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• 2016

최근 지구온난화 및 각종 미세먼지 문제 등을 해결하기 위한 방안으로 친환경 운송수단에 대한 관심이 증폭되고 있다. 이에 따라 자동차 배기가스 규제는 더욱 강화되고 있으며, 내연기관이 아닌 새로운 동력원을 활용하는 친환경 자동차의 개발이 요구되고 있다. 이러한 요구를 만족시키며, 지속 가능한 운송수단에 대한 연구 및 개발을 자극하기 위해서 지난 30년 전부터 American Solar Challenge/ World Solar Challenge 라는 이름의 태양광 자동차 랠리가 미국 및 호주에서 진행되어 왔다. 본 기고에서는 American Solar Challenge (ASC) 참관 내용 및 World Solar Challenge에 대해 소개하며, 이를 바탕으로 향후 솔라카 개발 방향에 대해 논하고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권1호
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• pp.305-308
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• 2014

Background: To investigate the indications of loop electrosurgical excision procedure (LEEP) and its overtreatment rates for the see and treat and three step strategies in cases of atypical squamous cells of undetermined cytology (ASC-US) and low grade intraepithelial neoplasia (LGSIL) cytology. Materials and Methods: We retrospectively analyzed colposcopy directed biopsy (CDB) and LEEP results of 176 paients with ASC-US or LGSIL cytologies who underwent colposcopic examination. Results: Initial cytologies were ASCUS in 120 women and LGSIL in 56. According to the see and treat approach immediate LEEP was performed for38 women. Among the remaining 138 women, LEEP was performed for 32 whose CDB results revealed CIN2/3 lesions. In the see and treat group the recognition of CIN2/3 was found to be 39.4%. The overtreatment rate was 60% as compared to 25% in the three step group. In CDB group detection of CIN 2 or greater lesions increased with 3 or more biopsies. Conclusions: In patients with ASC-US/LGSIL cytologies CDB should be performed before LEEP to prevent overtreatment, with attention to all suspected areas and more than 2 biopsies taken.

• 대한치과의사협회지
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• 제14권4호
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• pp.377-379
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• 1976

Lower right first and second molar missings were restored by unilaterally designed removable partial denture, not to disturb the phonetic function. Terminal abutment teeth were splinted and ASC52 attachment aws used as a direct retainer. After that, oral examination and Roentgenographic examination were done periodically for 2 years. There were no remarkable changes on the abutment teeth and its surrounding structures. Also, there no phonetic disturbances by the appliance.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4945-4950
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• 2014

Infection with human papillomavirus (HPV) could affect genesis of both cervical and esophageal cancers. The type-specific distribution of HPV in cervical cytology abnormalities of women has remained unclear in Shantou, an esophageal cancer high-incidence area of China. Data from 22,617 women who were subjected to cervical HPV DNA testing with simultaneous cervical cytological examination during 2009-2013 were therefore here retrospectively evaluated in a hospital-based study. Overall, 16.2% (3,584/22,114)of women with normal cytology were HR-HPV positive, with HPV-52 (4.07%) as the most common type followed by -16 (3.63%), and -58 (2.46%). Prevalence of HR-HPV was 50.3% (253/503) in women with cervical cytological abnormalities, of which in ASC-H 71.4%, ASC-US 39.1%, HSIL 80.3% and LSIL 73.7%. HPV-58 (14.12%) was the most common type for all cervical cytological abnormalities, followed by HPV-16 (13.72%), and -52 (12.72%), while the more common HPV-16 type in ASC-H (42.9%) and HSIL (36.1%), HPV-52 and -58 were the most common types for ASC-US (10.3%) and LSIL (25%), respectively. Multiple HPV co-infections were identified in 33.2% (84/253) cytology abnormalities with positive HR-HPV, and the highest prevalence of HPV-58/16 combination in HSIL (28.6%, 6/21) was observed. Our data indicated a relative high prevalence of HPV-58 and -52 in women with cervical cytological abnormalities, which should be considered in the development of next-generation vaccines for Shantou.

• 인터넷정보학회논문지
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• 제20권5호
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• pp.27-36
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• 2019

본 연구에서는 공개된 뇌파 데이터인 DEAP(A Database for Emotion Analysis using Physiological Signals) 데이터 세트를 활용한 감정분류 분석 및 정확도 향상에 대한 실험을 진행하였다. 실험에는 32명에 대한 32개의 뇌파측정 채널 데이터가 모두 사용되었다. 전처리과정에서는 뇌파 데이터에 대한 256Hz 샘플링작업을 진행하였고, 유한 임펄스 응답 필터를 사용하여 주파수 대역별로 쎄타(4-8Hz), 슬로 알파(8-10Hz), 알파(8-12Hz), 베타(12-30Hz), 감마(31-45Hz) 파형에 대한 데이터를 추출하였다. 추출한 데이터는 시간-주파수 변형을 통하여 데이터의 상태를 구분한 후에, 독립성분분석방법을 통해 잡음(Artifact)을 제거하여 데이터를 정제했다. 도출된 데이터는 분류기 기계학습 알고리즘 실험을 시행할 수 있도록 CSV 파일로 변형 하였으며, 감정분류에는 Arousal-Valence 평면을 사용하였다. 감정은 "긍정적(Positive)", "부정적(Negative)" 이외에 평온한 상태로 존재하는 "중립적(Neutral)"의 3가지 상태로 분류하였다. 정확도를 개선하기 위해서 랜덤 포레스트(Random Forest) 알고리즘에 속성 선택적 분류기(Attribute Selected Classifier: ASC) 방식에 의해 선택된 속성을 적용하여 실험하였다. 정확도는 "각성(Arousal)" 부분에서 Koelstra의 결과보다 "32.48%" 높은 결과가 도출되었고, Liu의 실험의 "정서가(Valence)"와 비교해보면 ASC(Random Forest) 결과가 "8.13%" 더 높은 결과를 도출하였다. 정확도를 개선하기 위해 ASC 방식을 적용한 랜덤 포레스트 분류기 실험결과에서는 전체평균을 기준으로 기존 연구 결과와 대비하여 "2.68%" 높은 정확도가 도출되었다.

• Nuclear Medicine and Molecular Imaging
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• 제41권6호
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• pp.546-552
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• 2007

목적: 유방암 환자에게 불필요한 액와림프절 전절제술을 예방하기 위해서는 감시림프절을 절제하여 전이 여부를 평가하는 것이 중요하다. 감시림프절 매핑을 위한 방사성교질중 antimony trisulfide colloid (ASC), tin colloid (TC), human serum albumin (HSA) 이상의 3가지 교질에 $^{99m}Tc$을 표지하여 각각에서 림포신티그라피, 감시림프절 매핑의 성적을 비교하였다. 대상 및 방법: 2001년 10월부터 2006년 12월까지 임상적으로 액와림프절 전이가 없는 조기 유방암 환자 총 397명에게 시행한 림포신티그라피와 수술 중 감시림프절 절제 동결절편 검사, 및 수술 후 병리 소견을 후향적으로 평가하였다. 림포신티그라피 영상 소견을 분석하고, 감시림프절의 발견율(identification rate)과 위음성율(false negative rate), 그리고 음성예측도(negative predictive value)를 구하여 각 군의 자료에 대해 Fisher 직접확률법으로 비교하였다. 결과: 202명에게는 $^{99m}Tc$ ASC를, 120명에게는 $^{99m}Tc$-TC를, 75명에게는 $^{99m}Tc$-HSA를 사용하였으며 평균 연령, 병기, 원발 종양의 크기 등에서는 각 군별 환자들 사이에 유의한 차이가 없었다. ASE는 59명에게는 유륜부 피내 혹은 피하주사법을 사용했으며 136명에게는 종양주위 주사를, 그리고 7명의 환자에게는 두 가지를 병용하였다. TC와 HSA를 사용한 환자들에게는 모두 피내 혹은 피하주사하였다. 액와림프절 전이는 ASE사용 군에서 33.2%, TC 사용군에서 31.7%, HSA 사용 군에서 22.7%였으며 통계적으로 유의한 차이는 없었다. 감시 림프절 발견율(IR) 과 위음성율(FNR) 그리고 음성예측도(NPV) 는 사용한 교질 ASC/TC/HSA 각각에 대해 99.0%, 21.5%, 90.5% / 96.7%, 20.5%, 90.7% / 94.7%, 17.7%, 94.7%로 사용한 교질의 종류에 따라 통계적으로 유의한 차이가 없었다. 감시림프절 매핑 성적은 방사성교질의 주사방법에 따라서 유의한 차이를 보이지 않았다. 림포신티그라피의 영상에서 감시림프절이 명확히 구분된 경우는 ASC에서 79.6%, TC 에서 92.5%, HSA에서 88.6%였다. 림프관이 관찰된 비율은 ASC에서 43.6%, TC에서 0.8%, HSA 에서 96.8%이었다. 림포신티그라피에서 관찰된 감시림프절의 개수는 HSA가 가장 많았지만 통계적으로 유의한 차이는 없었다. 결론: ASC, TC 및 HSA등의 방사성교질을 이용한 감시림프절 매핑 성적은 서로 유의한 차이를 보이지 않았다.

• Journal of Microbiology and Biotechnology
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• 제22권5호
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• pp.575-584
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• 2012

Listeria monocytogenes is an important foodborne pathogen that comprises four genetic lineages: I, II, III, and IV. Of these, lineage II is frequently recovered from foods and environments and responsible for the increasing incidence of human listeriosis. In this study, the phylogenetic structure of lineage II was determined through sequencing analysis of the ascB-dapE internalin cluster. Fifteen sequence types proposed by multilocus sequence typing based on nine housekeeping genes were grouped into three distinct sublineages, IIA, IIB, and IIC. Organization of the ascB-dapE internalin cluster could serve as a molecular marker for these sublineages, with inlGHE, inlGC2DE, and inlC2DE for IIA, IIB, and IIC, respectively. These sublineages displayed specific genetic and phenotypic characteristics. IIA and IIC showed a higher frequency of recombination (${\rho}/{\theta}$). However, recombination events had greater effect (r/m) on IIB, leading to its high nucleotide diversity. Moreover, IIA and IIB harbored a wider range of internalin and stress-response genes, and possessed higher nisin tolerance, whereas IIC contained the largest portion of low-virulent strains owing to premature stop codons in inlA. The results of this study indicate that IIA, IIB, and IIC might occupy different ecological niches, and IIB might have a better adaptation to a broad range of environmental niches.

• 한국실내디자인학회논문집
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• 제17권2호
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• pp.111-121
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• 2008

In recent years, Korean population aged 65 and over has grown faster(7.2% in 2000, 14.4% projected in 2018 and 20.0% in 2026) than the other age groups and average life expectancy has increased from 65.8 years in 1980 to 75.9 years in 2000. The Aging Simulation Center(ASC) was built for people to give educational chance for further understanding of the elderly and the environment for the aged. People are able to recognize the changes including hearing loss, vision changes, and changes in the ability to touch and move after experiencing the simulated daily life of older persons. In general, ASC is composed of residential setting area and exhibition area of daily commodities for the elderly and care person. Currently, there are four ASCs in Korea. The purpose of this study is to evaluate the characteristics of space design and design elements of ASCs and to suggest design implementation for better residential environment for the elderly. For the research purpose, design characteristics such as floor plans and spatial design elements of three ASCs were analyzed and compared. As a whole, space design of three ASCs was almost same without distinguished characteristics. The major finding of this study indicates that the ASC is considerably helpful environment to understand aging. However, some of design elements such as lighting should be supplemented for safety issue. It is recommended for future design of ASC to include exterior space including outdoor stairs, paths and roads and so on. In addition, reception and preparation area should be arranged with universally designed furniture.