• 제목/요약/키워드: ASB

검색결과 48건 처리시간 0.017초

Stage-specific Expression of Ankyrin and SOCS Box Protein-4 (Asb-4) during Spermatogenesis

  • Kim, Soo-Kyoung;Rhim, Si Youn;Lee, Man Ryul;Kim, Jong Soo;Kim, Hyung Jun;Lee, Dong Ryul;Kim, Kye-Seong
    • Molecules and Cells
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    • 제25권2호
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    • pp.317-321
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    • 2008
  • Members of the large family of Asb proteins are ubiquitously expressed in mammalian tissues; however, the roles of individual Asb and their function in the developmental testes have not been reported. In this report, we isolated a murine Asb4 from mouse testis. Northern blot analysis revealed that mAsb-4 was expressed only in testes and produced in a stage-specific manner during spermatogenesis. It was expressed in murine testes beginning in the fourth week after birth and extending into adulthood. Pachytene spermatocytes had the highest level of expression. Interestingly, the human homologue of mAsb-4, ASB-4 (hASB-4) was also expressed in human testis. These results suggest that ASB-4 plays pivotal roles in mammalian testis development and spermatogenesis.

The Roles of Market-Based Learning and Customer Orientation in Shaping Effective Selling Behavior and Efforts

  • Park, Jeong Eun;Kim, Seongjin;Lee, Sungho
    • Asia Marketing Journal
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    • 제11권2호
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    • pp.37-51
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    • 2009
  • Although previous studies have made significant progress in adaptive selling behavior (ASB), few studies have considered salesperson's customer orientation (CO) and learning behavior as determinants of effective sales management (ASB and relationship-making efforts), despite the discussion of important roles of these constructs. The authors test not only the relationships of salesperson's CO and market-based learning behavior to ASB and relationship-making efforts, but also the effects of ASB on relationship-making efforts and performance. The results of the study, which is done with samples of salespeople from Korean companies, indicate that salesperson's CO and market-based learning behavior are identified as significant determinants of ASB. Moreover, both salesperson's ASB and relationship-making efforts have significant effects on sales performance. On the other hand, as per salesperson's relationship-making efforts, salesperson's CO has a positive effect, but salesperson's market-based learning behavior and ASB do not influence his or her relationship-making efforts, which suggest a provocative possibility of conceptualization regarding the relationship between ASB and relationship management efforts.

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다슬기로부터 칼슘락테이트의 제조와 품질특성

  • 김순동;이예경;이명예;장경호
    • 한국식품저장유통학회:학술대회논문집
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    • 한국식품저장유통학회 2003년도 춘계총회 및 제22차 학술발표회
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    • pp.122-122
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    • 2003
  • 다슬기의 분말(PSB)과 그 회화분(ASB)으로부터 체내 흡수력이 높은 젖산칼슘의 제조조건과 색상, 용해도 및 관능적 품질을 조사하였다. PSB로부터 제조한 젖산칼슘(PSB-CL)의 PSB 및 젖산 100 mL에 대한 수율은 젖산농도가 10%일 때는 300% 및 15 g, 20%일 때는 260% 및 20 g이었으며, ASB로 제조한 젖산칼슘(ASB-CL)의 ASB 및 젖산 100 mL에 대한 수율은 10% 젖산에서는 400% 및 60 g, 20% 젖산에서는 329% 및 66 g으로 원료량을 기준으로 하였을 때는 다같이 젖산농도의 증가에 따라 감소하였으나 젖산의 부피를 기준으로 하였을 때는 젖산농도의 증가에 따라 증가하였다. Dehydated PSB-CL 및 ASB-CL 제조의 적정온도와 시간은 10$0^{\circ}C$에서는 각각 4 및 5시간, 12$0^{\circ}C$에서는 3 및 4시간, 15$0^{\circ}C$에서는 1 및 2시간으로 ASB-LA의 경우가 짧았다. IR 및 H-NMR spectrum의 분석결과 PBS-LA와 ASB-LA의 구조는 Ca($CH_3$CHOH$CO_2$)$_2$임이 확인되었다. 무수 PSB-CL 및 ASB-CL의 칼슘함량은 각각 15.4%(w/w)와 17.3%(w/w)로 이론 값의 각각 84.2%와 94.5%를 나타내었으며, 미량의 Fe, Na, Mn Zn을 함유하였다. PBS-CL와 ASB-CL의 색상은 각각 연한 황색과 연녹색을 지닌 백색을 띠었다. pH 3~8로 조정한 증류수에서 PSB-CL과 ASB-CL의 평균 용해도는 각각 5.43 g/100 mL 및 6.11 g/100 mL로 standard CL의 4.74 g/mL에 비하여 높았다. 국간장을 제외한 대부분의 액체식품(3% 소금물, 소주, 진간장, 국간장, 포도주스 및 오렌지주스)에서의 용해도는 PSB-CL(3.14~5.03 g/100 mL)과 ASB-CL(4.69~6.05 g/100 mL)이 standard CL(2.94~5.84 g/100 mL)에 비하여 높았다. 관능검사 결과, ASB-CL은 신맛이 낮아 사용범위가 높은 것으로 평가되었으며 PSB-CL는 쓴맛은 높으나 떫은맛이 낮고 구수한 맛이 강하여 식품에의 응용이 기대된다.

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Expression of Murine Asb-9 During Mouse Spermatogenesis

  • Lee, Man Ryul;Kim, Soo Kyoung;Kim, Jong Soo;Rhim, Si Youn;Kim, Kye-Seong
    • Molecules and Cells
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    • 제26권6호
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    • pp.621-624
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    • 2008
  • We previously showed that Asb-4 and Asb-17 is uniquely expressed in developing male germ cells. A recent report showed that Asb-9 is specifically expressed in the kidney and testes; however, detailed expression patterns in developing germ cells have not been shown. Northern blot analysis in various tissues demonstrated that mAsb-9 was strongly expressed in the testes. Expression analysis by RT-PCR and Northern blot in developing mouse testes indicates that mAsb-9 is expressed from the fourth week after birth to adulthood, with the highest expression in round spermatids. Expression sites were further localized by in situ hybridization in the testes. Pachytene spermatocytes and spermatids expressed mAsb-9 but spermatogonia and generated spermatozoa did not. This study reveals that mAsb-9 could be a specific marker of active spermatogenesis and would be useful for studies of male germ cell development.

한국 해군의 전략 수립 방향 연구 - 미군의 JOAC, ASB 개념 분석과 한국 해군에의 함의- (This paper asks whether the Republic of Korea (ROK) Navy should Study on ROK Navy's Strategy Planning - Concerning to JOAC, ASB Concept of US Armed Forces -)

  • 나성민
    • Strategy21
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    • 통권32호
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    • pp.5-35
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    • 2013
  • The purpose of this thesis is to suggest how to plan ROK(Republic of Korea) Navy's strategy concerning to JOAC(Joint Operation Access Concept) and ASB(Air-Sea Battle) concept of US(United States) armed forces. Since 2006, US armed forces has been developing CONOPS(Concepts of Operations), JOAC & ASB. These concepts will not only affect security environment for Korea Peninsula and West Pacific Area, but also will be affected to ROK Navy's Strategy. Therefore, Korea Navy has to consider and review those concepts and should discuss the way to secure peace of Korea Peninsula. JOAC & ASB have been developed for securing operational access ability of US armed forces against enemy forces. A2/AD(Anti-Access, Area-Denial) is the strategy of possible enemy forces against US forces' approaching into the operation area and impede operations within area. US forces had to overcome enemy's A2/AD strategy in coming century to protect national interest and sustain global leadership. The main concept of JOAC & ASB is "Cross-domain Synergy", which means 'to eliminate duplicate and improve joint operability containing space and cyber operation area.' Korea Navy's acceptance of JOAC & ASB without any revising is not a rational choice. Without the amendment some problems can be occurred by the Korea navy's acceptance for the original version of JOAC & ASB. Those are "Missing differences of operation environment between Korea and US", "Impediment from neighbor nations, especially PRC (People's Republic of China)", and "Impediment inside from Korea armed forces". Therefore, Korea Navy has to evaluate and find out the way to solve for JOAC & ASB to apply for their strategy and minimise those possible problems above. This thesis is expected to be the solution.

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Single nucleotide polymorphisms for parentage testing of horse breeds in Korea

  • Sun-Young Lee;Su-Min Kim;Baatartsogt Oyungerel;Gil-Jae Cho
    • Animal Bioscience
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    • 제37권4호
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    • pp.600-608
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    • 2024
  • Objective: In this study, we aimed to evaluate the usability single nucleotide polymorphisms (SNPs) for parentage testing of horse breeds in Korea. Methods: The genotypes of 93 horse samples (38 Thoroughbred horses, 17 Jeju horses, 20 Quarter horses, and 18 American miniature horses) were determined using 15 microsatellite (Ms) markers (AHT4, AHT5, ASB2, ASB17, ASB23, CA425, HMS1, HMS2, HMS3, HMS6, HMS7, HTG4, HTG10, LEX3, and VHL20) and 101 SNP markers. Results: Paternity tests were performed using 15 Ms markers and 101 SNP markers in Thoroughbred horses and Quarter horses. AHT5, ASB2, ASB17, ASB23, CA425, HMS7, HTG10, and LEX3 did not follow Mendelian inheritance in Thoroughbred horses, whereas in Quarter horses, only AHT4, ASB2, and HMS2 showed Mendelian inheritance, consequently, paternity was not established. Meanwhile, 31 markers, including MNEc_2_2_2_98568918_BIEC2_502451, in Thoroughbred horses, and 30 markers, including MNEc_2_30_7430735_BIEC2_816793, in Quarter horses did not conform with Mendelian inheritance and therefore, could not be used for establishing parentage. Conclusion: The possibility of replacing Ms markers with SNP markers for paternity testing in horses was confirmed. However, further research using more samples is necessary.

Microsatellite DNA형에 의한 더러브렛 말의 친자감정예 (A case of parentage testing in the Thoroughbred horse by microsatellite DNA typing)

  • 조길재;양영진;김봉환
    • 대한수의학회지
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    • 제43권1호
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    • pp.25-29
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    • 2003
  • This study was carried out to investigate a usefulness of the microsatellite DNA markers for parentage verification of Thoroughbred (TB) horses. 9 TB horses samples were genotyped for nine international minimum standard markers (AHT4, 5, ASB2, HMS3, 6, 7, HTG4, 10, and VHL20), and the additional panel of four markers, ASB17, CA425, LEX33, and TKY321. This methods consisted of multiplexing PCR procedures, and it showed reasonable amplification of all PCR products. Genotyping was performed with an ABI 310 genetic analyzer. Foal I was excluded according to principles of Mendelian genetics in AHT4 (H/K), ASB2 (Q/Q), HMS3 (I/P), HTG4 (M/O), HTG1O (K/R), VHL20 (M/P), ASB17 (F/N), LEX33 (M/O), and TKY321 (G/I) markets. Foal II was excluded with markers AHT5 (K/M), ASB2 (M/N), HMS7 (N/N), HTG1O (K/K), VHL20 (I/I), ASB17 (F/F) and TKY321 (G/I). Foal III was excluded with markers AHT4 (O/O), AHT5 (K/K), ASB2 (M/R), HMS6 (M/P), HMS7 (O/O), HTG10 (R/S), VHL20 (L/M), and ASB17 (N/O). These results suggest that the present DNA typing is so useful for parentage verification of TB horses.

National Culture and Relational Selling: Antecedents, Outcomes and Boundary Conditions of ASB and Customer-Oriented Selling in Korea

  • Park, Jeong Eun;Deitz, George D.
    • Asia Marketing Journal
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    • 제18권1호
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    • pp.75-97
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    • 2016
  • Globalization and the emergence of new markets has placed increased emphasis on cross-cultural sales and marketing research. Despite considerable advances in the personal selling literature, little is known about the cross-cultural transferability of key constructs. Given the degree to which well-accepted relational sales behaviors such as ASB and customer oriented selling reflect Western values such as individualism and low uncertainty avoidance, the relative efficacy of such practices in alternative cultural context is less clear. Using a Korean sample, our results confirm the beneficial direct effects of these relational selling practices upon performance. However, we also find strong workgroup interdependence diminishes the effects of ASB and that performance fully mediates the relationship between both sales behaviors and job satisfaction. In contrast to prior results, we find female salespeople and those newer to their position demonstrate stronger ASB.

비대칭 슬림플로어 합성보의 내화성능 산정에 관한 해석적 방법 연구 (A Study on the Analytical Method for Fire Resistance Calculation of Asymmetric Slimfloor Beam)

  • 박수영;박원섭;김흥열;홍갑표
    • 한국화재소방학회논문지
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    • 제24권2호
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    • pp.31-37
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    • 2010
  • 비대칭 슬림플로어 합성보(Asymmetric Slimfloor Beam, 이하 ASB)는 비대칭 형강의 일부를 콘크리트 슬래브에 삽입한 합성보로서, 유럽에서 개발되었다. 근래 국내에서도 건축물의 층고저감, 물량감소, 내화 성능 증대 등의 목적으로 ASB의 연구가 진행되고 있다. 본 연구에서는 실험을 통하여 ASB의 내화성능을 확인하고, 열전달해석을 통하여 내화성능 시간에서의 모멘트 내력(Moment capacity)을 산정하였다. 그 결과를 바탕으로 방화석고보드와 ASB로 구성된 3시간 내화구조를 선정하고, 내화 성능을 검토하였다.

곤드레 또는 참취를 함유한 빵의 뇌신경 보호효과 (Neuroprotective Effects of Bread Containing Cirsium setidens or Aster scaber)

  • 권기한;임희경;정미자
    • 한국식품영양과학회지
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    • 제43권6호
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    • pp.829-835
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    • 2014
  • 본 연구는 $H_2O_2$에 의해 유도된 사람 뇌 신경모세포종 SK-N-SH의 사멸에 대항하여 곤드레 및 참취 추출물(CS와 AS)을 함유한 빵의 뇌신경세포 보호 작용에 대한 것이다. 곤드레 추출물을 함유한 곤드레 빵 추출물(CSB) 또는 참취 추출물을 함유한 참취 빵 추출물(ASB)을 SK-N-SH에 처리하면 $H_2O_2$에 의해 유발된 세포독성이 추출물 처리에 의해 감소되었고 세포 내 활성산소종과 p-p38 수준이 감소하였다. 관능검사에서 CS를 함유한 곤드레빵, AS를 함유한 참취 빵 그리고 CS 또는 AS를 함유하지 않은 일반 빵을 비교한 결과, 외관, 색상, 향미, 부드러움 그리고 종합적인 기호도에 대해 CSB와 ASB는 NB보다 높은 점수를 받았으나 CSB와 ASB와는 차이가 없었다. 이 결과들은 뇌신경세포에서 항산화 효과와 p38 인산화 억제에 의해 산화적 스트레스에 대항하여 뇌신경 보호 효과를 나타내는 CSB와 ASB의 건강 유익성을 보여주었다. 따라서 CS와 AS는 건강 기능성 소재로 활용될 수 있을 것이다.