• Journal of the Korean Society of Systems Engineering
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• v.13 no.1
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• pp.15-23
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• 2017

This paper describes verification of APR1400 reactor vessel by applying the system engineering approach, in which the design re-engineering method is used to check the design parameters of APR1400 RV (reactor vessel). The RV is classified as safety class 1 and therefore must adhere strictly to the rules of ASME BPVC section III, subsection NB and seismic category I. This study explores designing the RV by following the ASME guidelines and making a comparative study with the current design. To meet this objective we apply system engineering methodologies to structure the process and allow for verification and validation of the major RV design parameters such as thickness of RV. The structural thicknesses of various part of RV are determined as well as reinforcements on the RV major nozzles. A 3D virtual reality model was created based on the design parameters using CATIA V5 and animation using Dassault Composer V2016. A comparison of re-engineered ARP1400 RV and standard APR1400 RV was done to show which design parameters were taken more conservative approach.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2187-2191
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• 2015

Background: Protrusive structures formed by migrating and invading cells are termed lamellipodia, filopodia, invadopodia and podosomes. Lamellipodia and filopodia appear on the leading edges of migrating cells and function to command the direction of the migrating cells. Invadopodia and podosomes are special F-actin-rich matrix-degrading structures that arise on the ventral surface of the cell membrane. Invadopodia are found in a variety of carcinomatous cells including squamous cell carcinoma of head and neck region whereas podosomes are found in normal highly motile cells of mesenchymal and myelomonocytic lineage. Invadopodia-associated protein markers consisted of 129 proteins belonging to different functional classes including WASP, NWASP, cortactin, Src kinase, Arp 2/3 complex, MT1-MMP and F-actin. To date, our current understanding on the role(s) of these regulators of actin dynamics in tumors of the orofacial region indicates that upregulation of these proteins promotes invasion and metastasis in oral squamous cell carcinoma, is associated with poor/worst prognostic outcome in laryngeal cancers, contributes to the persistent growth and metastasis characteristics of salivary gland adenoid cystic carcinoma, is a significant predictor of increased cancer risk in oral mucosal premalignant lesions and enhances local invasiveness in jawbone ameloblastomas.

• Applied Biological Chemistry
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• v.25 no.4
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• pp.257-260
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• 1982

During the rice storage at $28^{\cir}{\pm}1^{\cir}C$ and $60{\sim}70%$ R.H., the moisture content of rice, was increased max. 1. 6% by the activity of rice weevil. The growth of Asp. repens was not affected, while Asp. niger was inhibited after the appearance of its second generation adults. The development of rice weevil was generally accelerated by both of Asp. repens and Asp. niger, but decelerated at higher density of Asp. niger($1.6{\times}10^4$ propagules/g). The total number of rice weevil showed no significant difference during six weeks.

• Journal of the Korean Society of Safety
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• v.11 no.2
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• pp.60-66
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• 1996

In order to look into the internal structure and electrical properties of insulating Silicone rubbers added reinforcing fillers ; Silica(0-140 phr ), and to examine the behavior of charged particles, and the properties of thermally stimulated current (TSC) are investigated, respectively. From the TSC which are formed by applying the electric field of 2~5 ㎸/mm to specimen at temperature range from -150 to $270^{\circ}C$, the results arp as following. In the case of non-filled specimen, four peaks of $\delta$, $\gamma$ , $\beta$ and u are obtained at the temperature of $-120^{\circ}C$, $-60^{\circ}C$, $20^{\circ}C$ and $130^{\circ}C$, respectively and the case of filled specimen, three peaks of $\delta$, ${\alpha}_2$ and ${\alpha}_1$ are observed at the temperature of of $-120^{\circ}C$, $80^{\circ}C$ and $130^{\circ}C$, respectively. The origins of these peaks are that, the $\delta$ peak seems to the result from the contribution of side chain methyl radical, and the $\beta$ peak from the depolarization of space charge polarization owing to added imputity during during manufacturing specimens, and the $\beta$ peak from the orientation of $Si-CH_3$dipole, and the ${\alpha}_2$ near the temperature of $130^{\circ}C$ from carboxyl acid that is formed by the thermal oxidation of high temperature.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.3
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• pp.579-588
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• 2009

Enterprises and governments currently utilize COTS (Commercial off-the-Shelf) based information systems which are a kind of component based systems. Especially, COTS are widely utilized as components of information security systems and information systems. This paper suggests an appropriate adaptation level and a cost effective priority to replace security functional components in security environment. To make a cost effective decision on adapting security functional components, this paper develops a hierarchical model of information security technologies and analyzes findings through multiple decision-making criteria.

• Nuclear Engineering and Technology
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• v.40 no.4
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• pp.319-326
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• 2008

To transport process wastes efficiently from the Advanced Spent Fuel Conditioning Pyro-process Facility (ACPF) at the Korea Atomic Energy Research Institute (KAERI), a new hot cell cask has been designed based on an existing hot cell padirac transport cask, with not only a neutron absorber for improved shielding capability, but also a docking facility for an easy docking system. In the new hot cell cask, two kinds of materials have been considered as shielding materials, polyethylene and resin. To verify the transport compatibility of the waste and spent fuel for the ACPF, neutron and photon shielding calculations were performed using the MCNPX code. The source term was evaluated by the ORIGEN-ARP code system based on spent PWR fuel. From the calculation, it was found that the maximum surface dose rates of the hot cell cask with the two candidates were estimated within the limit (2 mSv/hr).

• International Journal of Oral Biology
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• v.47 no.4
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• pp.55-62
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• 2022

Bioactive flavonoids have been shown to improve the biological activity of stem cells derived from different sources in tissue regeneration. The goal of this study was to see how naringin, a natural flavonoid discovered in citrus fruits, affected the biological properties of human dental pulp stem cells (HDPSCs). In this study, we found that naringin increases the migratory ability of HDPSCs. Naringin increased matrix metalloproteinase-2 (MMP-2) and C-X-C chemokine receptor type 4 (CXCR4) mRNA and protein expression in HDPSCs. ARP100, a selective MMP-2 inhibitor, and AMD3100, a CXCR4 antagonist, both inhibited the naringin-induced migration of HDPSCs. Furthermore, naringin increased osteogenic differentiation of HDPSCs and the expression of the osteogenic-related marker, alkaline phosphatase in HDPSCs. Taken together, our findings suggest that naringin may be beneficial on dental tissue or bone regeneration by increasing the biological activities of HDPSCs.

• Nuclear Engineering and Technology
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• v.53 no.12
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• pp.4179-4188
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• 2021

This study identifies efficient earthquake intensity measures (IMs) for seismic performances and fragility evaluations of the reactor containment building (RCB) in the advanced power reactor 1400 (APR1400) nuclear power plant (NPP). The computational model of RCB is constructed using the beam-truss model (BTM) for nonlinear analyses. A total of 90 ground motion records and 20 different IMs are employed for numerical analyses. A series of nonlinear time-history analyses are performed to monitor maximum floor displacements and accelerations of RCB. Then, probabilistic seismic demand models of RCB are developed for each IM. Statistical parameters including coefficient of determination (R²), dispersion (i.e. standard deviation), practicality, and proficiency are calculated to recognize strongly correlated IMs with the seismic performance of the NPP structure. The numerical results show that the optimal IMs are spectral acceleration, spectral velocity, spectral displacement at the fundamental period, acceleration spectrum intensity, effective peak acceleration, peak ground acceleration, A95, and sustained maximum acceleration. Moreover, weakly related IMs to the seismic performance of RCB are peak ground displacement, root-mean-square of displacement, specific energy density, root-mean-square of velocity, peak ground velocity, Housner intensity, velocity spectrum intensity, and sustained maximum velocity. Finally, a set of fragility curves of RCB are developed for optimal IMs.

• The Bulletin of The Korean Astronomical Society
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• v.45 no.1
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• pp.37.1-37.1
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• 2020

Cosmic-ray protons (CRp) are efficiently produced at starburst galaxies (SBGs), where the star formation rate (SFR) rate is high. In this talk, we present estimates of gamma-ray and neutrino emissions from nearby SBGs, M82, NGC253, and Arp220. Inside the starburst nucleus (SBN), CRp are accelerated at supernova remnant (SNR) shocks as well as at stellar wind (SW) termination shocks, and their transport is governed by the advection due to starburst-driven wind and diffusion mediated by turbulence. We here model the momentum distributions of SNR and SW-produced CRp with single or a double power-law forms. We also employ two different diffusion models, where CRp are resonantly scattered off large-scale turbulence in SBN or self-excited waves driven by CR streaming instability. We then calculate gamma-ray/neutrino fluxes. The observed gamma-ray fluxes by Fermi-LAT, Veritas, and H.E.S.S are well reproduced with double power-law distribution for SNR-produced CRp and the CRp diffusion by self-excited turbulence. The estimated neutrino fluxes are <~10-3 of the atmospheric neutrino flux in the energy range of Eneutrino <~100 GeV and <~10-1 of the IceCube point source sensitivity in the energy range of Eneutrino >~60 TeV.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.21 no.3
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• pp.303-313
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• 2023

Spent fuels (SFs) are stored in a storage pool after discharge from nuclear power plants. They can be transferred to for the further processes such as dry storage sites, processing plants, or disposal sites. One of important measures of SF is the burnup. Since the radioactivity of SF is strongly dependent on its burnup, the burnup of SF should be well estimated for the safe management, storage, and final disposal. Published papers about the methodology for the burnup estimation from the known activities of important radioactive sources are somewhat rare. In this study, we analyzed the dependency of the burnup on the important radiation source activities using ORIGEN-ARP, and suggested simple correlations that relate the burnup and the important source activities directly. A burnup estimation equation is suggested for PWR fuels relating burnup with total neutron source intensity (TNSI), initial enrichment, and cooling time. And three burnup estimation equations for major gamma sources, ¹³⁷Cs, ¹³⁴Cs, and ¹⁵⁴Eu are also suggested.