• 제목/요약/키워드: ARID1A

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한방치료에 따른 천식환자의 삶의 질에 대한 임상적 평가 (Clinical Study of Quality-of-Life in Asthmatic Patients managed by Oriental Medical Treatments)

  • 주창엽;허태석;정희재;정승기;이형구;한동하
    • 대한한방내과학회지
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    • 제21권4호
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    • pp.575-581
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    • 2000
  • Objective : Asthma is a lung disorder characterized by periodic attacks of wheezing alternating with periods of relatively normal breathing. And quality of life in asthmatic patients shows a tendency to decrease. So we had a clinical study whether if oriental medical treatment could improve their quality of life or not. Methods : The 15 cases were new patients that visited at division of respiratory system, department of internal medicine in Kyunghee medical center from the 1 st of July, 2000 to the 1 st of August. All of them were diagnosed as asthma and treated by western medical therapy. We used a Quality of Life Questionnaire for adult Korean Asthmatics(QLQAKA) and evaluated the results after two times answers, at an interval of two weeks. Results : The mean of the first answer was 2.84 marks and 3.36 ones after two weeks. If there is a difference of over 0.5 points between the two, we can admit significant effect. After the asthmatic patients treated by oriental medical therapy, they gained a difference of 0.52 points, 10.4%. Conclusions : We suggest that oriental medical therapy can improve the quality of life of asthmatic patients arid we can alternate side effects of western medical therapy with oriental one. if they carry out two different treatments at the same time.

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A Plant Metabolomic Approach to Identify the Difference of the Seeds and Flowers Extracts of Carthamus tinctorius L.

  • Ozan Kaplan;Nagehan Saltan;Arzu Kose;Yavuz Bulent Kose;Mustafa Celebier
    • Mass Spectrometry Letters
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    • 제14권2호
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    • pp.42-47
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    • 2023
  • Carthamus tinctorius L. (known as safflower) is a valuable oil plant whose importance is increasing rapidly in the world due to its high adaptation to arid regions. The seeds of this unique plant are especially used in edible oil, soap, paint, varnish and lacquer production. Its flowers are used in vegetable dye production and medicinal purposes beside its features as a coloring and flavoring in food. After the oil is removed, the remaining pulp and plant parts are used as animal feed, and dry straw residues are used as fuel. Beside all these features, its usage as a herbal medicinal plants for various diseases has gained importance on recent years. In this study, it was designed a plant metabolomic approach which transfers all the recent data processing strategies of untargeted metabolomics in clinical applications to the present study. Q-TOF LC/MS-based analysis of the extracts (70% ethanol, hexane, and chloroform) for both seed and flowers was performed using a C18 column (Agilent Zorbax 1.8 µM, 100 × 2.1 mm). Differences were observed in seed and fruit extracts and these differences were visualized using principal component analysis (PCA) plots. The total number and intersections of the peaks in the extracts were visualized using peak count comparison graph. Based on the experimental results, the number of the detected peaks for seeds was higher than the ones for the flowers for all solvent systems to extract the samples.

저밀도 폴리에틸렌의 표면개질과 이를 이용한 저밀도 폴리에틸렌/알루미늄 라미네이트의 접착특성 (Surface Modification of Low Density Polyethylene and Adhesion Characteristics of Low Density Polyethylene/Aluminum Laminate)

  • 정배영;류승훈
    • Elastomers and Composites
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    • 제36권3호
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    • pp.195-200
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    • 2001
  • UV조사 하에서 아크릴산의 그라프팅을 이용한 LDPE의 표면개질을 XPS와 접촉각을 이용하여 살펴보았으며, 이에 따른 알루미늄/LDPE 라미네이트의 접착력 변화를 살펴보았다. 접촉각은 UV조사시간이 증가함에 따라 초기에 급격히 감소하다가 점차 일정한 값을 나타내었다. 이는 초기에는 LDPE 표면에 그라프트된 아크릴산에 의해 친수성이 급격히 증가하다가 표면의 아크릴산 농도가 증가함에 따라 친수성의 변화가 상대적으로 감소하기 때문으로 생각된다. 이러한 결과는 XPS를 이용한 O1s/C1s 비의 증가로도 확인할 수 있었다. 아크릴산이 그라프트된 LDPE와 알루미늄의 접착력은 순수한 LDPE를 이용하였을 때에 비하여 약 30배치 증가를 나타내었으며 이는 아크릴간의 그라프트에 의해 LDPF의 표면 극성기가 증가하였기 때문이다. 황산/isodium dichromate를 이용하여 알루미늄 표면을 처리한 경우 보다 뛰어난 접착력을 나타내었다. 아세트산의 존재하에서 LDPE/알루미늄 라미네이트의 계면접착력은 급격히 감소함을 알 수 있었다.

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저수지에 있어서 암거배수 방법이 작물수량에 미치는 효과에 관한 시험연구 (Study on the effects of crop-yields under subsurface drainage system in the water-logging paddy fields)

  • 서승덕;김조웅
    • 한국농공학회지
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    • 제19권3호
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    • pp.4449-4461
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    • 1977
  • Subsurface Drinage Problems arise from many causes. Flatland tends to be poorly drained, particularly where the subsoil permeability is low. There are many wet areas, however, where there is no evident connection between the area of seepage, or a high water table, and the topography of the site. High water tables may occur where the soil is either slowly or rapidly permeable, where the climate is either humid or arid, and where the land is either sloping or flat. This study is to bring light on subjects relating to increasing yield of crop and possibility of double crops a year in water logging paddy fields. Obtained results are briefly summarized as follows: 1. Effect of crop-yield in the plot A resulted 20.2 percent higher than the ordinary plot with yield of brown rice. 2. Possibility of double-crops a year is investigated. Effect of the barley production of the test plot resulted 168.2 percent higher than the other uplands near test plot with the yield of 1977 production and it is 3.8 percent higher compare with the yearly yields. 3. Decreasing depth of water level was measured 23.9mm per day and 14.3mm per day at the test plot and ordinary plot respectively and the amounts of subsurface drainage measured 30mm to 35mm per day. It is required that the relief well should be controled carefully and adequately. 4. Mean depth of ground water levl was measured 0.4∼0.5m regardless the width of corrugated pipe. It is significantly lowere than the ordinary plot(0.15∼0.20m) 5. The ground temperature of the test plot is higher 1 degree of centigarade or more than the ordinary plot and soil moisture content of the ordinary plot is higher 12.4∼27.8 percent than the plot reversely. There should be a relationship between rising of ground temperature and soil moisture.

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An option to provide water and fertilization for rice production in alkaline soil: fertigation with slow release fertilizers (SRFs)

  • Young-Tae Shin;Kangho Jung;Chung-Keun Lee;Jwakyung Sung
    • 농업과학연구
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    • 제49권4호
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    • pp.923-931
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    • 2022
  • An increasing global population requires a greater food supply, and accordingly there is demand for enhanced production of rice, as a major crop plant that covers half of the world's population. Rice production in arid area is extremely difficult due to poor soil fertility, salinity, deficit of irrigation water, and weather conditions. The aim of the present study was to determine whether various fertilization recipes could provide a countermeasure to allow rice production while also providing soil amendment such as soil pH adjustment. The study was conducted at an experimental field of the United Arab-Emirates (UAE) from January to April, 2022. Rice seedlings (cv. Asemi, alkaline-resistant) were transplanted in plastic containers, and different types of water and nutrient managements were employed as follows: water management (flooding and aerobic for NPKs treatment group) and nutrient management (NPKs, slow release fertilizers [SRFs] and SRFs + NPK-1 treatment groups with flooding). Water and nutrient management did not show any effect on soil pH adjustment. Rice growth was significantly enhanced in the flooding compared to the aerobic condition, whereas the effect of nutrient management clearly differed among the treatment groups, with SRFs + NPK-1 showing the best results followed by SRFs and NPKs. Most of the fertilization groups markedly accumulated soluble sugars in the shoots and grains of rice plants, but concomitantly a decrease in the roots. Overall, the level of starch showed a tendency of relatively slight perturbation by fertilization. Taken together, the results indicate that soil physical structure should be preferentially amended to find the key for suitable rice production.

Antioxidant Effects of Ascorbic Acid on Renal-Ischemia Reperfusion Injury in Rabbit Model

  • Kim, Jong-Man;Lee, Jae-Yeon;Kim, Duck-Hwan;Jeong, Seong-Mok;Park, Chang-Sik;Kim, Myung-Cheol
    • 한국임상수의학회지
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    • 제25권3호
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    • pp.165-169
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    • 2008
  • Renal ischemia-reperfusion (I/R) injury is great clinical important because viability of the organ depends on the tolerance to ischemia-reperfusion injury, an inevitable processing during surgery. The purpose of this study was to investigate the effects of premedicated ascorbic acid alone in I/R injury model induced by cross-clamping of renal vessels. In the rabbit models, 2-4 kg New Zealand white rabbits were subjected to 30 minutes of warm unilateral renal ischemia followed by removal of contralateral kidney and then divided into five groups, control (2) arid treatment groups (3). In control group 1, the rabbits only received right nephrectomy. In control group 2, the rabbits received I/R on left kidney after the right nephrectomy. In treatment group 1, the rabbits received ascorbic acid 50 mg/kg IV before the operation. In treatment group 2, the rabbits received ascorbic acid 100 mg/kg IV before the operation. In treatment group 3, the rabbits received ascorbic acid 200 mg/kg IV before the operation. Blood samples were collected from these rabbits for measurement of kidney function tests at the 0, 1 st, 3rd and 7th day and antioxidant enzyme( SOD, GSHPx, CAT) at 24 hours. Kidney function tests (serum creatinine and BUN) showed a significant difference between group 2 and group 4, 5. Activity of antioxidant enzymes in plasma were significant decrease in group 4, 5 compare to group 2. The result of this study suggested that the exogenous ascorbic acid had a role of attenuation of renal I/R injury in rabbit model.

내민길이를 고려한 $700kg/cm^2$ 고강도 콘크리트 골조의 구조적거동 (The Structural Behavior of $700kg/cm^2$ High Strength Concrete Frames Considering Extension Distances at Joints)

  • 신성우;안종문;윤영수;이승훈
    • 콘크리트학회지
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    • 제6권5호
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    • pp.140-148
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    • 1994
  • R/C 라멘골조에 있어서 수직부재(기둥, 벽등)에 수평부재(보, 슬라브등)의 콘크리트 강도보다 1.4배가 넘는 강도의 콘크리트를 분리타설할 경우 ACI 318R-89 R10.13.1은 수직부재에 타설한 콘크리트가 수평부재로 2ft(60cm)이상의 내민길이를 확보하도록 규정하고 있다. 이에 따라 본 연구는 이규정을 그대로 적용하기에 앞서 실험적인 검증을 통한 구조적인 안전성을 확보하기 위하여 고강도 콘크리트 내민길이, 콘크리트 압축강도 등을 주요변수로 하여 총 6개의 실험체를 제작하여 실험 및 분석하였다. 실험결과 압축강도 및 내민 길이의 증가에 따라 각 실험체의 연성능력은 증가하는 것으로 나타났으며 R/C 라멘골조에 고강도 콘크리트와 보통강도 콘크리트를 분리타설할 경우 균열발생상황, 접합부에서의 거동 등을 고려할 때 고강도 콘크리트의 내민길이는 2h(h=보의 전체춤) 정도를 확보하여야 할 것으로 보여진다.

한국산 사과의 품종별 펙틴물질들에 관한 연구 (A Study on Pectic Substances of Korean Apple Varieties)

  • 임화재;이혜수
    • 한국식품조리과학회지
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    • 제2권1호
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    • pp.65-70
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    • 1986
  • 수확적기의 한국산 사과품종별 총펙틴함량과 각 펙틴 fraction 함량을 알아보고 2% Sodium hexa metaphosphate (SHMP)로 추출한 펙틴의 품종간 그리고 시판 펙틴과의 성분을 비교하였다. Nitta 방법에 의해 정량한 사과의 품종별 펙틴함량은 건조중량으로 1.76∼4.0%로 품종간에 차이를 보여 국광이 4.0%로 가장 높았으며 스퍼 얼리 브래이스 골덴 딜리셔스, 후지, 홍옥의 순이었다. 각 펙틴 fraction을 보면 용해성 펙틴함량은 국광이 가장 낮았고 스퍼 얼리 브레이스와 골덴 딜리셔스가 가장 높았다. 한편 스퍼 얼리 브레이스와 골덴 딜리셔스의 불용성 펙틴함량이 낮은 것으로 보아 이 두 사과는 숙성초기에 펙틴물질이 많이 변하는 것 같다. 2% SHMP로 추출한 총펙틴질의 성분 분석에서 회분함량은 사과품종간에 차이를 보이며 시판 펙틴보다 높았다. Anhydrogalacturonic acid (AUA) 함량은 시판 펙틴보다 낮으며 품종간에 범위가 다양했다. 메톡실함량은 시판펙틴보다 높으며 모든 사과품종이 70% 이상의 에스터화정도를 가졌다.

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한방병원 병상 실태와 한방 간호의 교육 현황에 따른 한방간호사 수요 예측에 대한 고찰 (The Present Educational Conditions and the Demanding Outlook of Nursing in Oriental Medicine)

  • 왕명자;안옥희;김희숙;옥도훈
    • 동서간호학연구지
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    • 제3권1호
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    • pp.39-49
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    • 1998
  • The purpose of this research is to provide basic data for the demanding outlook and the Nursing education by grasping the present educational conditions of nursing in oriental medicine. The results of survey and study on 112 nationwide schools (47 Department of nursing and 65 Nursing junior colleges) and data of the Korean Oriental Medicine Association and General Assembly in Sep. 1998 are as follows. 1. The number of nurse Oriental Medicine hospitals require in 2002 will have increased at least 700 or more. Public health centers' and other centers' requirements will increase more and more. 2. Education of nursing in oriental medicine is offered at practice in 14 universities (29.8%) among 47 Universities and 35 colleges (53.8%) among 65 colleges. 3. Nursing education in Oriental Medicine is mostly offered in the first term of the second year at universities with 5 to 10 points, and the second term of the third year at colleges with 2 points. According to this result, we would like to suggest as follows; A nurse whose main interesting subject is human beings will be an important figure as a medical information administrator in 21 century, namely, a nurse will play the leading part in the hospital administration more than a doctor. We must take much more interest arid exert ourselves in developing education of nursing in oriental medicine because in the future it will be the one and only field in the world, so we can export our Nursing manpower.

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Effect of Superovulatory Regimens on Ovarian Response and Embryo Production in Fine Wool Sheep in Tropics

  • Naqvi, S.M.K.;Gulyani, R.;Pareek, S.R.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권5호
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    • pp.595-599
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    • 2000
  • Fine wool sheep (n=18) maintained in a tropical environment were allocated to three treatment groups. Estrus was induced with two injections of $PGF_{2{\alpha}}$ (10 mg. im) at 10 days interval. Superovulation treatment started 2 days prior to the second injection of $PGF_{2{\alpha}}$. Each ewe was treated with a total dose of 25 units FSH (Super-OV) i.m. every 12 hover 3 days; Group 2 were also injected i.m. with 200 IU PMSG at the first injection of FSH; Group 3 was treated as in Group 2 and also with GnRH ($4{\mu}g$ Buserelin) at the onset of estrus. The ewes in estrus were mated with a fertile ram. Ovarian examination and recovery of embryo and ova were performed at laparoscopy and laparotomy on day 3 or 4 after mating. Data for onset of estrus, duration of estrus, number of corpora lutea (CL), number of unnovulated large follicle (LF), embryo recovery rate, embryo quality and fertilization recorded for the 3 groups. Ewes in the Group 1 set in estrus later (p<0.05; $50.0{\pm}7.29h$) than the ewes in Group 2 ($24.5{\pm}3.58$) and 3 ($32.5{\pm}3.58h$). The duration of estrus, ovarian size and ovarian response (number of CL and LF) did not differ significantly (p>0.05) among the 3 groups. The proportion of ewes with a superovulatory response (${\geq}2$ CL) was the lowest (50%) in Group 1 treated with FSH alone but ova/embryo recovery (100%) and fertilization (100%) was significantly (p<0.05) higher than Group 2 (58.3 and 85.7%, respectively) and Group 3 (48.6 and 50%, respectively). It is concluded that in tropical fine wool sheep, there is no difference in the 3 treatments for yield of good quality embryos but ovarian response and ovulation rate increased on additional use of PMSG and GnRH respectively to FSH alone.