• Journal of Microbiology and Biotechnology
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• v.32 no.5
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• pp.672-679
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• 2022

Microbial lipases are used widely in the synthesis of various compounds due to their substrate specificity and position specificity. 4-Ethyl malate (4-EM) made from diethyl malate (DEM) is an important starting material used to make argon fluoride (ArF) photoresist. We tested several microbial lipases and found that Photobacterium lipolyticum M37 lipase position-specifically hydrolyzed DEM to produce 4-EM. We purified the reaction product through silica gel chromatography and confirmed that it was 4-EM through nuclear magnetic resonance analysis. To mass-produce 4-EM, DEM hydrolysis reaction was performed using an enzyme reactor system that could automatically control the temperature and pH. Effects of temperature and pH on the reaction process were investigated. As a result, 50℃ and pH 4.0 were confirmed as optimal reaction conditions, meaning that M37 was specifically an acid lipase. When the substrate concentration was increased to 6% corresponding to 0.32 M, the reaction yield reached almost 100%. When the substrate concentration was further increased to 12%, the reaction yield was 81%. This enzyme reactor system and position-specific M37 lipase can be used to mass-produce 4-EM, which is required to synthesize ArF photoresist.

• The Korea Journal of Herbology
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• v.23 no.3
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• pp.141-147
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• 2008

Objectives : The cortex and root of Acanthopanax sessiliflorus (AR), a herbal medicine, have been used for several diseases including cancer in Oriental countries. Recently, we reported that AR has an immune-potentiating action. Oga-Power(OP) was made using extract from AR. For these reasons, we hypothesized that OP can potentiate the immune system in terms of accelerating proliferation rates of immune cells such as thymocytes and splenocytes. Methods : In this experiment, proliferation rates of thymocytes and splenocytes were measured using modified 3-[4,5-dimethy -lthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT). No production levels in macrophages isolated from normal mice were measured using Griess method. Results : In our results, treatment with OP accelerated proliferation rates of splenocytes, but did not affect those of thymocytes in vitro. On the other hand, proliferation rates of thymocytes was elevated in vivo. In addition, level of NO production from macrophage separated from abdominal cavity of normal mice was elevated by treatment with OP. Conclusions : In conclusion, OP has immune-potentiating action, by acceleration of splenocyte proliferation and elevation of NO production level from macrophages.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.05a
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• pp.805-807
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• 2016

By using ICT in the manufacturing industry with the advent of "Industry 4.0" of Germany, it has been promoted a lot of research to maximize the production capacity. Be particularly increased manufacturing complexity, increase the information delivered to the operator, augmented reality technologies in order to maximize production have been studied. In this paper, in order to solve the deficiencies problem that frequently occurs in the actual site, using the augmented reality technology, provides a system for providing personal training information to the worker. Proposed system, by fusing worker information and process another job, generates educational information of the individual, it is to provide information through the video of the tablet. When using such methods, it is expected that it is possible to improve the production quality of the manufacturing industry to overcome the deficiencies problem that frequently occurs through the continuing education of employees.

• Journal of Biomedical Engineering Research
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• v.13 no.4
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• pp.275-284
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• 1992

Development of Integrated Speech Training Aids for Hearing Impaired In this study, a spepch lralnlng aids that can do real-time display of vocal tract shape and other speech parameters together in a single system is implemenLed and self-training program for this system is developed. To estimate vocal tract shape, speech production process is assumed to be AR model. Through LPC analysis, vocal tract shape, intensity, and log spcclrum are calculated. And, fundamental frequency and nasality are measured using vibration sensors.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2003.11a
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• pp.90-95
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• 2003

Chemical management of annulus gas system is carried out for the purpose of ensuring the safety and reliability of the system via securing the integrity of the system, detecting the D$_2$O in-leakage of coolant and/or moderator, and reducing the radiation dose. Since the quality of CO_2$ gas, which is used as a filling gas for annulus gas system at CANDU plants, has a propound effect on the integrity of the system material and the radiation dose, CO_2$ gas of high quality is needed. If the quality of CO_2$ gas does not meet the specification, it may give rise to undesirable effect not only on the annulus gas system, but also on the environment due to the production of radioactive nuclei. Therefore, it is very important to check the impurities of CO_2$ gas. Based on this background, the inventories of C-14 and Ar-41 in CO_2$ gas that is supplied as annulus gas were estimated using the data on concentrations of the impurities of $CO_2$ such as C, N_2$ and Ar. The results of this study is expect to give useful information on optimization of CO_2$ impurities maintenance and management of gaseous radioactive wastes produced at CANDU plants.

• Korean Journal of Food Science and Technology
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• v.13 no.1
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• pp.74-89
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• 1981

Breadmaking is a complex system in which many variables govern the production of acceptable bread. Lipids, a minor component of wheat flour, function importantly in bread-making. Shortening, or fat, is one of the essential ingredients in commercial baking. Beneficial shortening effect depends on type and quantity of lipids present in wheat flour and also on wheat flour quality. Surfactants have been used in baking industry during last decade because certrain surfactants can replace shortening and/or natural flour lipids. A proper combination of lipidshortening-surfactant is more useful in the production of specialty breads such as whole wheat breads, high protein breads, high fiber breads or even non-wheat composite breads rather than in the production of regular white breads. This presentation is a review of recent studies on the contribution of flour lipids, shortening, and surfactants, alone or in combination in the production of breads; illustrations are mainly from data obtained in the author's laboratory.

• The Korea Journal of Herbology
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• v.23 no.3
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• pp.163-173
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• 2008

Objectives : Imyosan (IMS), a drug preparation comprised of Phellodendri Cortex (PC) and Atractylodis Rhizoma (AR), is commonly used as a traditional herbal medicine in Korea and China for the treatment of various inflammatory diseases. However, little is known about the effect of IMS and its component herbs on inflammatory mediators in RAW 264.7 cells. Therefore, in this study, methanol extracts of IMS and its component herbs were examined to determine if they inhibited inflammatory effects in RAW 264.7 cells. Methods : Cytotoxic activity of IJHT and its components on RAW 264.7 cells was using 5-(3-carboxymethoxyphenyl)-2H-tetrazolium inner salt (MTS) assay. The nitric oxide (NO) production was measured by Griess reagent system. And proinflammatory cytokines were measured by ELISA kit. The levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression were detected by western blot. Results : Methanol extract of IMS and its component herbs were significantly reduced iNOS and COX-2 expression as well as NO, PGE2, $IL-1{\beta}$ and IL-6 production in RAW 264.7 cells. Conclusions : The results of this study indicated that the anti-inflammatory effect of Imyosan extract is more potent than that of extracts of its component herbs in macrophages.

• Journal of Ocean Engineering and Technology
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• v.24 no.1
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• pp.178-184
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• 2010

Today, there has been a decrease in international shipping because of the weakening in global economies. Therefore, shipowners are thinking more about Floating Production Storage and Offloading (FPSO), which can perform functions related to the transporting, storage, and tracking of crude oil from oil wells. Given the huge expense of these special ships, shipowners require workers who can solve problems quickly and secure sustainable production functions in this age of globalization. Furthermore, it is important to design, construct, and maintain facilities so that a ship remains in operation over a long term. This paper discusses a system that uses knowledge-based AR to help workers improve their understanding and deal with pipeline equipment problems safely. In addition, it displays a 3CAD model and status information for products to improve their recognition on the FPSO that they intend to inspect. At the same time, the system works quickly and offers solutions for dangerous circumstances or malfunctions. It thus helps to maintain the functionality of the FPSO throughout its life-cycle.

• Electronics and Telecommunications Trends
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• v.34 no.2
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• pp.10-18
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• 2019

Since the introduction of CRT(Cathode Ray Tube) in the 1950s, display technologies have been developed continuously. Flat panel displays such as PDP(Plasma Display Panel) and LCD(Liquid Crystal Display) were commercialized in the late 1990s, and OLED(Organic Light Emitting Diodes) and Micro-LED(Micro-Light Emitting Diodes) are now being developed and are becoming widespread. In the future, we expect to develop ultra-realistic, flexible, embedded sensor displays. Ultra-realistic display can be applied to AR/VR(Augmented Reality/Virtual Reality) devices and spatial light modulators for holography. The sensor-embedded display can be applied to robots; electronic skin; and security devices, including iris recognition sensors, fingerprint recognition sensors, and tactile sensors. AR/VR technology must be developed to meet technical requirements such as viewing angle, resolution, and refresh rate. Holography requires optical modulation technology that can significantly improve resolution, viewing angle, and modulation method to enable wide-view and high-quality hologram stereoscopic images. For electronic skin, stable mass production technology, large-area arrays, and system integration technologies should be developed.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.80-83
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• 2009

본 논문에서는 AR 보드 게임을 위한 FTIR 방식의 멀티 터치 스크린 시스템을 제안한다. 기존 보드 게임은 카드의 정보나 위치등 다양한 정보를 보여주면서 사용자와의 상호작용에 있어서 버튼과 같은 단순한 형태의 입력을 요구한다. 이러한 낮은 상호작용을 보완하기 위해서 다양한 형태의 패턴 등을 입력할 수 있는 멀티 터치 스크린 시스템을 적용한 텐저블 사용자 인터페이스를 제공하여 사용자로 하여금 더 많은 상호작용과 높은 몰입감을 제공하고자 한다. 본 논문에서 제안하는 시스템은 다음과 같이 구성된다. 먼저, 텐저블 사용자 인터페이스를 위해서 Jefferson Y. Han이 제안한 시스템과 유사한 형태의 FTIR 방식의 멀티 터치 스크린을 테이블 탑 형태로 제작한다. 또한, 스크린 위의 카드를 인식하기 위해서 특정한 모양의 패턴을 적용한 적외선 반사지를 카드에 입힌 후, DI 방식을 사용하여 카드의 고유한 정보를 인식할 수 있도록 하였다. 마지막으로 사용자에게 인터페이스의 확장뿐만 아니라 시각적으로 높은 몰입감을 제공하기 위해 Bimber가 제안한 Virtual Showcase를 적용하였다. 이러한 시스템을 통해 사용자는 이전의 단조로운 형태의 게임에서 벗어나 훨씬 다양하고 높은 몰입감을 즐길 수 있게 되었다.