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Evaluation of Autonomic Function in Patients with Hyperhidrosis by Power Spectral Analysis of Heart Rate Variability (심박변이도(Heart Rate Variability) 측정을 통한 다한증(多汗症)환자의 자율신경계(自律神經系)기능 평가)

  • Lee, Kun-Young;Lee, Hyung-Koo;Jung, Sung-Ki;Jung, Hee-Jae
    • The Journal of Internal Korean Medicine
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    • v.29 no.1
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    • pp.1-11
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    • 2008
  • Objectives : Essential hyperhidrosis is a socially and occupationally disabling disorder. There are many suggestions that hyperhidrosis is associated with the autonomic nervous system. This study was designed to investigate the autonomic nerve system the patients with hyperhidrosis. Methods : 348 palmar and plantar hyperhidrosis patients and 20 systemic hyperhidrosis patients in the ambulatory care were investigated. All patients were inspected at the first medical examination, using the PSA of HRV. HRV was measured for 5 minutes after 5 minutes' bed rest. We checked the frequency domain analysis of HRV (i.e. TP, VLF, LF, HF and LF/HF) which were transformed into natural logarithm of patients against the standard measures of the HRV components. Then, we compared the means of patients with means and highest values of in the normal range of Koreans 1) between the patients with palmar and plantar hyperhidrosis and the healthy controls and 2) between the patients with the systemic hyperhidrosis and healthy controls, by the frequency domain analysis of heart rate variability (HRV), respectively. We then compared the results between 1) and 2). Results : The values of natural logarithmic measures of LF/HF ratio in the patients with palmar and plantar hyperhidrosis we examined were significantly higher than the values of healthy controls, but those in the patients with systemic hyperhidrosis were not higher. Conclusion : This study suggests that the autonomic nervous function did not simply increase but that the balance between sympathetic and parasympathetic nervous function did matter in patients with palmar and plantar hyperhidrosis. This balance included that the sympathetic nervous function aggravated comparatively with parasympathetic nervous function. On the other hand, we couldn't find any significance of the patients with the systemic hyperhidrosis as for the autonomic nervous function.

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A Study of Serum Thyroglobulin in Various Thyroid Diseases (각종 갑상선질환에서 혈청 Thyroglobulin치에 관한 연구)

  • Kim, Chang-Kook;Jeon, Byung-Sook;Han, Bong-Heon;Ro, Heung-Kyu;Lee, Bok-Hui
    • The Korean Journal of Nuclear Medicine
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    • v.17 no.1
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    • pp.17-23
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    • 1983
  • In an attempt to evaluate the diagnostic singnificance of the serum thyroglobulin (TG) in various thyroid disease states, authors measured serum TG by radioimmunoassay technique in 20 cases of normal subject, 22 cases of hyperthyroidism, 12 cases of diffuse nontoxic goiter (DNG) and 96 cases of nodular nontoxic goiter(NNG). The results were as follows: 1. In 20 cases of normal subjects, serum TG level was $20.41{\pm}5.5ng/ml(M{\pm}S.D.)$. There was no significant difference between males ans females. 2. In 22 cases of hyperthyroidism, serum TG level was $60.23{\pm}34.56ng/ml$ and the range was from 22 to 175 ng/ml, which were significantly high levels comparing with normal controls (p<0.01). 3. In 12 cases of euthyroidism with DNG, serum TG was $37.28{\pm}27.36ng/ml$ and the range was from 14 to 89 ng/ml. In 96 cases of euthyroidism with NNG, serum TG was $70.43{\pm}78.18ng/ml$ and the range was from 12.8 to 440 ng/ml. Both groups showed significantly increased levels of TG than normal control (p<0.01). 4. 57 cases of NNG patients were analysed pathologically by operation or needle biopsy and the TG level of each disease group is as follows. Thyroid carcinoma (16 cases); $72.2{\pm}81.71ng/ml$, adenomatous goiter without cystic degeneration (15 cases); $74.86{\pm}45.64ng/ml(M{\pm}S.D.)$ and adenomatous goiter with cystic degeneration(23 cases); $73.56{\pm}64.78ng/ml(M{\pm}S.D.)$. There was no significant difference between each group. Also the TG levels of thyroiditis (5 cases) was $19.6{\pm}8.96ng/ml(M{\pm}S.D.)$. 5. There were no significant correlations between serum thyroid hormones and serum TG in each thyroid functional states.

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The Effect of Silica binder content ans Sintering condition on the Strength of Zircon-based Shell Mold (실리카 바인더 함량과 소결조건이 지르콘계 주형의 강도에 미치는 영향)

  • Kim, Jae-Won;Kim, Du-Hyeon;Kim, In-Su;Seo, Seong-Mun;Jo, Hae-Yong;Kim, Du-Su;Jo, Chang-Yong;Choe, Seung-Ju
    • Korean Journal of Materials Research
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    • v.10 no.6
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    • pp.415-421
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    • 2000
  • The effect of silica binder content on the mechanical properties of zircon shell mold was investigated. Content of binder silica sol to refractory powder in weight[$R_W$] was adjusted from 0.18 to 0.43. Sintering of the shell mold was carried out in the temperature range of $871^{\circ}C$ to $1400^{\circ}C$. Green strength of the shell mold at room temperature increased with increasing $R_W$ and sintering temperature up to $1300^{\circ}C$. However, the mold with $R_W$ of 0.43 that sintered at $1400^{\circ}C$ for 3 hours showed relatively low strength and large level of porosity. The mechanical behavior of the shells is supposed to attributed to the difference in thermal expansion coefficient between refractory powder and binder silica. The optimum value of $R_W$ for zircon-based shell molds was found to be 0.33.

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Improved Cooking Methods for Dry Beans and their Effects on Quality of Cooked Products (두류의 Quick Cooking방법 개발과 이것이 제품 품질에 미치는 영향)

  • Lee, Y.C.;Shin, D.B.;Shin, D.W.
    • Korean Journal of Food Science and Technology
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    • v.15 no.3
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    • pp.307-313
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    • 1983
  • Soybeans ans black-eyed peas, chosen as test samples of dry beans, were subjected to soaking and cooking treatments to develop quick cookig methods and study their effects on quality of cooked products. The results of the study are summarized as follow: 1. Of the soaking methods tested, soaking soybeans in 3% sodium bicarbonate (SBC) solution and black-eyed peas in 0.5-1% SBC solution followed by cooking them in water at $95-100^{\circ}C$ required 40 minutes and 10 minutes of cooking time, respectively. When compared to 180 minutes of cooking time for soybeans and 40 minutes of that for black-eyed peas by conventional cooking method (Control), soaking dry beans in optimum SBC solutions reduced cooking time by over 80%. 2. Among cooking methods tested, steam cooking at $121^{\circ}C$ was the most effective one in reducing cooking time of soybeans (15 min.). Black-eyed peas sacked in water required 6 minutes of cooking time in 1% SBC solution at $95-100^{\circ}C$, and 5 minutes of that in steam at $121^{\circ}C$. 3. Quality of cooked beans with optimum texture was evaluated by sensory panel and Gardner Color Difference Meter. Beans cooked in steam at $121^{\circ}C$ had better overall quality than those cooked by other methods. Beans soaked in optimum SBC solution had quality as good as control, whereas beans cooked in SBC solution had worse quality than control. 4. These results indicated that cooking time of soybeans could be drastically reduced by either steam cooking at $121^{\circ}C$ or soaking in 3% SBC solution followed by cooking in water at $95-100^{\circ}C$. Cooking time of black-eyed peas could be significantly shortened by either steam cooking at $121^{\circ}C$ or soaking in 0.5-1% SBC solution followed by cooking in water at $95-100^{\circ}C$.

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Finite Element Analysis of Stress Distribution in using Face Mask according to Traction Point (훼이스 마스크의 견인위치에 따른 응력분포에 관한 유한요소법적 연구)

  • Oh, Kyo-chang;Cha, Kyung-Suk;Chung, Dong-hwa
    • Journal of Dental Rehabilitation and Applied Science
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    • v.25 no.2
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    • pp.171-181
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    • 2009
  • The objective of this study was to analyse stress distribution of maxillary complex by use of face mask. The construction of the three-dimensional FEM model was based on the computed tomography(CT) scans of 13.5 years-old male subject. The CT image were digitized and converted to the finite element model by using the mimics program, with PATRAN. An anteriorly directed force of 500g was applied at the first premolar 45 degrees downwards to the FH plane and at the first molar 20 degrees downwards to the FH plane. When 45 degrees force was applied at maxillary first premolar, there were observed expansion at molar part and constriction at premolar part. The largest displacement was 0.00011mm in the x-axis. In the y-axis, anterior displacement observed generally 0.00030mm at maximum. In the z-axis, maxillary complex was displaced 0.00036 mm forward and downward. When 20 degrees force was applied at maxilla first molar, there were observed expansion at lateral nasal wall and constriction at molar part. The largest displacement was 0.001mm in the X-axis. In the Y-axis, anterior displacement observed generally 0.004mm at maximum. In the Z-axis, ANS was displaced upward and pterygoid complex was displaced downward. The largest displacement was 0.002mm.

Die Notwendigkeit einer funktionalen Grammatik fur Deutsch als Fremdsprache (외국어로서 독일어 수업을 위한 기능문법의 필요성)

  • Park Hyun-Sun
    • Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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    • v.7
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    • pp.237-256
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    • 2003
  • Das Deutsche als Fremdsprach hat sich als akademische Disziplin etabliert; es hat seine - von vielerlei Irrungen und Wirrungen begleitete - Startphase hinter sich und ist in eine Phase der Konsolidierung eingetreten. Bei aller Unterschiedlichkeit der $Ans\"{a}tze$, Forschungsmethoden und Lemziele gibt es doch eine Einheit in der Vielfalt, was angesichts der erst wenige ]ahrzehnte alten Disziplin erstaunt. Im Zentrum stehen nach allgemeiner Auffassung die Theorie und Praxis des Lehrens und Lernens/ Erwerbens des Deutschen als Fremdsprache; unterschidliche Auffassungen bestehen vor allem daruber, ob Deutsch als Fremdsprache ein germanistisches oder aber ein fremdsprachenphilologisches Fach sei. Unbestritten sind dagegen Fremdperspektive und $Interdisziplinarit\'{a}t$ der Disziplin rnit zahlreichen Beztigen zu Nachbarwissenschaften. Eine wesentliche Rolle in der Diskussion spielte stets die Rolle der Grammatik im fremdsprachlichen Deutschunterricht. Freilich hat die Diskussion ergeben, dass dieses in Wahrheit eine Scheinaltemative ist, die auf einer Reihe falscher Annahmen oder $Missverst\"{a}ndnissen$ beruht, vor allem jenen, im Unterricht komme es $ausschlie{\ss}lich$oder zurnindest vorrangig auf Fertigkeiten und Kommunikation an, nicht oder nur am Rande auf die Vermittlung sprachsystematischer Erkenntnisse. Durchgesetzt hat sich heute freilich die Erkenntnis, dass Grammatik, verstanden in diesem weiten Begriffssinn, aus dem Fremdsprachenunterricht nicht zu verbannen ist. Weiterhin $d\"{u}rfte$ Einvemehmen dariiber herrschen, dass Grammatik und Kommunikation keinen Gegensatz darstellen, vielmehr das Lernziel kommunikative Kompetenz die Beherrschung grammatischer Regeln einbezieht, wenn nicht voraussetzt. Der Funktionsbegriff ist umstritten. Der Oberbegriffe $f\"{u}r$ alle Funktionen $w\"{a}re$ Kommunikation. Fur unser Verstandnis einer funktionalen Grammatik fur Lemende des Deutschen als Fremsprache ist die entscheidende Frage, welche Funktion in der Kommunikation eine bestimmte Struktur spielt. Das Ziel oder der Zweck der kommunikativen Handlung steht im Mittelpunkt. Wir meinen, dass auch jenseits des deutschen Sprachraums Form und Funktion des sprachlichen Zeichens eine Einheit darstellen und im Unterricht nicht getrennt werden $k\"{o}nnen$. Zuerst lernen wir die Formen und Strukturen sprachlicher Mittel kennen, und danach werden wir sie praktisch an: Regelwissen, aber Versagen in der Kommunikation. Die Beispiele der sprachlichen $M\"{o}glichkeiten$ der Satzarten unter funktionalem Aspekt und des Ausdrucks der $Modalit\"{a}t$ im Deutschen machen die Notwendigkeit eines funktional-kommunikativen Ansatzes einer Grammatik fur Deutsch als Fremdsprache deutlich. Es belegt zugleich, dass - unter dem Primat des Didaktischen - die Grenze von Grammatik und Lexikon $\"{u}berwinden$ werden muss, um den Lemenden wirkliche $Erkl\"{a}rung$ und Lernhilfen zu bieten.

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Phylogenetic study of Korean Geranium(Geraniaceae) based on nrDNA ITS squences (ITS 염기서열에 의한 한국산 쥐손이풀속(Geranium)의 계통학적 연구)

  • Woo, Jeong Hyeon;Park, Seon-Joo
    • Korean Journal of Plant Taxonomy
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    • v.36 no.2
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    • pp.91-108
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    • 2006
  • Phylogenetic analyses were conducted to evaluate evolution and relationship of 16 taxa of Korean Geranium including 3 outgroups using ITS (internal transcribed spacer) squences of nuclear ribosomal DNA. Phylogenetic studies used most parsimony and neighbor-joining methods including bootstrapping and jackknifing analysis. As the result, Korean Geranium forms monophyletic group. In the parsimony tree G. koraiense var. hallasanense situated as the most basal clade and Erianthum group forms one clade by high bootstrap ans jackknife values (100% of bootstrap and jackknife values). G.dahuricum as one of the Krameri group is closely related with Palustre group by very weak relationship (37% of bootstrap and 44% of jackknife values) and the node collapse in the strict tree. G. Knuthii which was one of wilfordii group is closely related with Koreanum group. G. sibiricum, one of Sibiricum group, is the most closest relationship with G. soboliferum and these species are sister to G. krameri. G. tripartitum and G. wilfordii which are wilfordii group are linked to G. nepalense, G. thunbergii f. pallidum and G. thunbergii. This result suggested that the phylogenetic analysis of ITS sequences should be useful to address phylogenetic questions on the genus Korean Geranium.

A clinical study on patients with Cold Hypersensitivity on hands and feet and their autonomic nervous system function using of Heart Rate Variability(HRV) (수족냉증 환자의 실태 및 HRV(Heart Rate Variability)를 이용한 자율신경계 기능 평가 연구)

  • Kim, Eun-Sook;Hwang, Jae-Ho;Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub;Choi, Jae-Ho
    • Journal of Oriental Medical Thermology
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    • v.5 no.1
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    • pp.1-13
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    • 2006
  • Objectives : This study was designed to analyze basic data for cold hypersensitivity patients with a questionnaire and investigate correlation between cold hypersensitivity and Heart Rate Variability(HRV). Methods : 49 patients who complain of cold hypersensitivity on hands and feet in ambulatory care were investigated in Oriental Gynecology, Kyunghee Oriental Medical Center and Women medical center, Kangnam Koreana hospital from May 1, 2006 to October 20, 2006. All patients were asked to answer a questionnaire. After careful I examination to rule out other disease which may affect Digital Infrared Thermal Imaging(DITI) and HRV data, patients were taken thermography for the diagnosis of cold hypersensitivity Based on the result of thermography, the patients were divided into two groups(Objective cold hypersensitivity and Subjective cold hypersensitivity). Then, these two groups were compared using HRV data which was measured in the supine position for 5 minutes. Results: 1. For most patients, cold hypersensitivity first developed during puberty. 2. The parts of the body that felt cold first time were hands and feet. 3. The cold sensation was increased in winter or at bedtime Showing that the sensation can be changed according to the level of coldness. 4. Among women who sufferfrom cold hypersensitivity, very few of them were treated. 5. More than half of cold hypersensitivity patients's family member also had a cold hypersensitivity. 6. The decrease in mean values of LF/HF ratio was observed in objective cold hypersensitivity group than subjective cold hypersensitivity group and the decrease was significant(P=0.014) when examined by Student t-test. Conclusions : It is necessary that the cold hypersensitivity patients should be treated carefully considering the facts mentioned above. And it can be suggested that dysautinomia be related with cold hypersensitivity and be evaluated by HRV.

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A Study on Virtual Reality Management of 3D Image Information using High-Speed Information Network (초고속 정보통신망을 통한 3차원 영상 정보의 가상현실 관리에 관한 연구)

  • Kim, Jin-Ho;Kim, Jee-In;Chang, Chun-Hyon;Song, Sang-Hoon
    • The Transactions of the Korea Information Processing Society
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    • v.5 no.12
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    • pp.3275-3284
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    • 1998
  • In this paper, we deseribe a Medical Image Information System. Our system stores and manages 5 dimensional medical image data and provides the 3 dimensional medical data via the Internet. The Internet standard VR format. VRML(Virtual Reality Modeling Language) is used to represent the 3I) medical image data. The 3D images are reconstructed from medical image data which are enerated by medical imaging systems such ans CT(Computerized Tomography). MRI(Magnetic Resonance Imaging). PET(Positron Emission Tomograph), SPECT(Single Photon Emission Compated Tomography). We implemented the medical image information system shich rses a surface-based rendering method for the econstruction of 3D images from 2D medical image data. In order to reduce the size of image files to be transfered via the Internet. The system can reduce more than 50% for the triangles which represent the surfaces of the generated 3D medical images. When we compress the 3D image file, the size of the file can be redued more than 80%. The users can promptly retrieve 3D medical image data through the Internet and view the 3D medical images without a graphical acceleration card, because the images are represented in VRML. The image data are generated by various types of medical imaging systems such as CT, MRI, PET, and SPECT. Our system can display those different types of medical images in the 2D and the 3D formats. The patient information and the diagnostic information are also provided by the system. The system can be used to implement the "Tele medicaine" systems.

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Survey on Personal Medicines in Cheju Island (제주도 민간요법에 관한 조사연구)

  • Lee, Kyung-Hee
    • Journal of East-West Nursing Research
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    • v.2 no.1
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    • pp.37-53
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    • 1997
  • The purpose is to inspect the personal medicines in Cheju island that are used traditionally and to get their characteristics. The subjectives are 39 Cheju people, men 10, women 29, who were horned, grown up in Cheju and agreed with this study. The ranges of age are 10 persons(m : 1, w: 9) over 40 less 50 years old, 14(m : 7, w : 7) over 50 less 60, 5(m : 1, w : 4) over 60 less 70, 6(m : 0, w : 6) over 70 less 80, and 4(m : 1, w : 3) over 80. The average age is 64.5 years old. The method to collect the data is 20 structured opening questionaires that are based on references. The duration to collect datas is 11days from 4th, Aprill 1997 to 14th, Aprill 1997. The workers who are trainned the interview methods went their villages and got answers after explaining the purpose and contents to them. Somtimes they used to record the answers. The analysis was identified the subjectives to four regions of Cheju, arranged answers with items, rearranged the same answers, counted with number and percentage. And classified the materials and characteristics. The results of this study are followed: The things that is used as personal medicines are the effects through experiences ans misteries that have hand down by word of mouth, even though they are not scientific. People used the materials arround their circumference. It is an accumulation of experiences. The ways used in eating, doing acupuncture or sting, exposing to smoke, wheedling, fixing after pounding. Almost materials are plants. Mugwort is effective in fever, gastritis, hemorrhoid, diarrhea, edematous hands or feet and dermatitis. Citron and Arrowroot in fever, gastritis. Seeds of Pumpkin in indigestive, hemorrhoid, edematous hands or feet. Gallic in fever, diarrhea, frostbite, dermatitis, and toothache. Motherwort in diarrhea, gastritis. Radish juice in indigestive, jaundice. Bean paste in burn, wound. Acupuncture in fever, gastritis, indigestive, back pain, edematous hands or feet. Sting as similar with it in fever, indigestive, edematous hands or feet. Cigarrette in hemorrhoid, wound, toothache. Cowstools in edematous hands or feet, wound. Sault is usded a lot in fever, gastritis, indigestive, hemorrhoid, uneffective voiding, edematous hands or feet, dermatitis, having a boil around the mouth, toothache, and eye disease. Japanese Parsley in fever, gastritis. Egg Apple in diarrhea, edematous hands or feet, frostbite. And Wild Chrysanthemum is effective in jaundice. In the conclusion, people used the things arround. A things is effective in several symptoms. If these are not effective, they would used the magic as god's anger. As locally, they used the grasses and fruits in the middle of Mt. Halla and seafood on the sea village.

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