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Current Status of Tetanus in Korea (한국에 있어서의 파상풍에 대한 고찰 (최근 10년간을 중심으로))

  • ;;;;;Ebosawa, Isao
    • Korean Journal of Health Education and Promotion
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    • v.2 no.1
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    • pp.122-132
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    • 1984
  • Aiming to obtain knowledge and information on tetanus occurrence in Korea, an analystical survey was carried out for registered and admitted patients in four large hospitals in Korea during January 1, 1974 through December 31, 1983. Tile results showed as follows: 1. 175 among total 453 tetanus patients died in the hospitals, therefore fatal rate showed as 24.1%. However, the discharged patients against doctors' advices were not included in these died cases. 2. Sex ratio of admitted tetanus patients between male and felame was shown as 3 : 1. 3. Home delivery in neonate tetanus and laceration and abrasion in non-neonate tetanus were observed as the most dominant cause of death respectively and the wound of foot lead the most dominant cause of death in the latter. 4. Clinical features of the tetanus patients on admission showed the following order in the frequency: sucking and disphagia failure(50.8%), convulsion (53.8%), trismus (50.8%). 5. The tetanus patients were terminated with mainly respiratory ani cardiac failure. 6. In the treatment for tetanus patients, airway (58.3%), intubation (45.3%) and tracheostomy(9.7%) were applied respectively.

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Effect of Eurycoma longifolia Jack on Laevator Ani Muscle in Both Uncastrated and Testosterone-Stimulated Castrated Intact Male Rats

  • Ang, Hooi-Hoon;Cheong, Hung-Seong
    • Archives of Pharmacal Research
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    • v.24 no.5
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    • pp.437-440
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    • 2001
  • It has been reported that Eurycoma longifolia Jack commonly known as Tongkat Ali has gained notoreity as a symbol of man's ego and strength by the Malaysian men because it increases male virility and sexual prowess during sexual activities. As such, the effects of 200, 400 and 800 mg/kg of butanol, methanol, water and chloroform fractions of E. longifolia Jack were studied on the laevator am muscle in both uncastrated and testosterone-stimulated castrated intact male rats after dosing them for 12 consecutive weeks. Results showed that 800 mg/kg of butanol, methanol, water and chloroform fractions of E. longifolia Jack significantly increased (p<0.05) the leavator am muscle to 58.56$\pm$1.22, 58.23 $\pm$0.31, 60.21 $\pm$0.86 and 62.35 $\pm$0.98 mg/100 g body weight, respectively, when compared with the control (untreated) in the uncastrated intact male rats and 49.23 $\pm$0.82, 52.23 $\pm$ 0.36, 50.21 $\pm$ 0.66 and 52.35 $\pm$ 0.58 mg/100 g body weight, respectivety, when compared to control (untreated) in the testosterone-stimulated castrated intact male rats. Hence the proandrogenic effect as shown by this study further supported the traditional use of this plant as an aphrodisiac.

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Fetal bladder outlet obstruction in a stillborn bovine fetus

  • Jeong, Won-Il;Lee, Cha-Soo;Chung, Jae-Yong;Jeong, Da-Hee;Do, Sun-Hee;Noh, Dong-Hyung;Oh, Won-Seok;Jeong, Kyu-Shik
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2002.11a
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    • pp.134-134
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    • 2002
  • A stillborn bovine male fetus with abdominal distention, arthrogryposis and atresia ani was presented for diagnostic evaluation. At necropsy, this fetus had a large amount of ascites, urachal obstruction and marked bladder distention. The ventral surface of the bladder had ruptured and attached to the abdominal wall by fibrinous adhesions. There was bilateral hydronephrosis with moderate pelvic dilatation and cortical attenuation. The rectum was filled with meconium but the anus was imperforate. The right forelimb was contracted. The cause(s) of these abnormalities could not be determined; however, we believe that developmental abnormalities during embryogenesis may be the result of chromosomal abnormalities. This report is the first to report congenital urachal obstruction in this species.

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Immune Suppression and Stimulation of Antioxidants -Effect of Propyl gallate on Murine Humoral Immune Functions and Methemoglobin Content- (한산화제의 면역억제 및 항진 연구 - 항산화제인 Propyl gallate가 체액성 면역기능과 Aniline 유도 Methemoglobin 함량에 미치는 영향 -)

  • 유충규;황미경
    • Journal of Food Hygiene and Safety
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    • v.3 no.2
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    • pp.83-88
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    • 1988
  • Propyl gallate used as an antioxidant was examined for its effects on murine Immune system and metbemoglobin content treated with anillne. As immunotoxicology assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathtoxicology, IgM plaque forming cells and Artbus reaction for humoral immunity. Propyl gallate's effects were observed as follows; 1. Propyl gallate decreased circulating leukocyte counts, dose dependently. 2. Relative immunoorgan weigbts were not affected. 3. Propyl gallate diminisbed IgM PFCs/spleen cell and IgM PFCs/spleen. 4. Propyl gallate decreased Arthus reaction. 5. Propyl gallate did not affect metbemogiobin content treated wltb aniIIne.

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Dynamic Parameters Identification of an Air Spring for Vibration Isolation of a Complex Testing System of COG Bonding Process (COG 본딩공정 고속복합 검사 시스템의 방진용 에어 스프링의 동적 파라미터 규명 연구)

  • Lee, Ju-Hong;Kim, Pil-Kee;Seok, Jong-Won;Oh, Byung-Joon
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.7
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    • pp.13-20
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    • 2010
  • Due to the recent quantum leaps forward in bio-, nano-, and information-technologies, the precisionization and miniaturization of mechanical and electrical components are in high demand. The allowable margin for vibration limits for such equipments is becoming stricter. In order to meet this demand, understandings on the characteristics of vibration isolation systems are highly required. Among the components comprising the vibration isolation system, air spring has become a focal point. In order to develop a complex defect tester for COG bonding of display panels, a vibration isolation system composed of air springs for mounting is considered in this study. The dynamic characteristics of the air spring are investigated, which is the most essential ingredient for reducing the vibration problem of the tester to the lowest level. Uncoupled dynamic parameters of the air spring are identified through MTS experiments, followed by suggestion of a model-based approach to obtain the remaining coupled dynamic parameters. Finally, the dynamic behaviors of the air spring are estimated and discussed.

A Study on the Fabrication of Al/TiCp Composites by Liquid Mixing method(I) (액상교반법에 의한 AI/TiCp 복합재료의 제조에 관한 연구(I))

  • Im, Jong-Guk;Kim, Myeong-Han;Choe, Jae-Ha
    • Korean Journal of Materials Research
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    • v.3 no.5
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    • pp.529-537
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    • 1993
  • The mecllanical properties of AI/TiCp composite fabrication by liquid mixing was investigat ed. The composites, containing 10 wt% Tic. were producwi using induction furnace with mechanical stirring. The amounts of' 1.5wt% Mg were, added to wetting agents. Thr presence of aluminum in TiC composites showed rnhanced strengrh without loss of ductility at room and clrvated temperatures. Espe cially, wear resistance was found to dramatically irnprovc. I3ul excess stirring d~terrninrd the mect~ani~ cal properties. Approximate values at present work were 500 rpm. There was no inrerfacial reaction of any kind and the interface remains clearly deineated.

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Regulatory Mutations for Anaerobic Inducible Gene Expression in Salmonella typhimurium

  • Soo, Bang;Lee, Yun-Joung;Koh, Sang-Kyun;An, Chung-Sun;Lee, Yung-Nok;Park, Yong-Keun
    • Korean Journal of Microbiology
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    • v.30 no.5
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    • pp.347-354
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    • 1992
  • New regulatory, loci which participate in the regulation of anaerobic inducible gene expression in Salmonella typhimurium were identified. We observed the regulatory network of new regulator mutations to various anaerobic inducible gene (1). Some anaerobic inducible lac fusions were also induced at low pH condition which was severe environment to withstand for its virulence at the place like phagolysosome. Sic oxygen-regulated regulatory mutants (oxr) isolated by Tn10 mutagenesis were divided into two groups. Five of them were found to show negative effect on the regulation of anaerobic gene expression, while on e showed positive effect on the regulation. Genetic loci of four oxr were identified with 54 Mud-P22 lysogens covering the whole chromosome of S. typhimurium, in the nearby region of map unit 87 min (oxr101), 63 min (oxr104), 97 min (oxr 105), and 57 min (oxr 106), respectively. Two oxr mutants were subjected to two-dimensional polyacrylamide electrophoretic analysis of anaerobic inducible proteins for searching the control circuitry of our oxr mutants.

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Formation ani Magnetic Properties of Iron-Nitrides due to Mechanical Alloying in $NH_3$ gas Atomosphere ($NH_3$ 가스분위기에서 Mechanical Alloying에 의한 질화철의 합성 및 자성)

  • Lee, Chung-Hye;Koyano, Tomas;So, Byeong-Moon;Hong, Jin-Woong
    • Proceedings of the KIEE Conference
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    • 1994.07b
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    • pp.1333-1335
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    • 1994
  • The nitrification of pure iron powders is found to occur even at room temperature by high energy ball milling in $NH_3$ gas atmosphere. The powders of metastable iron nitrides ($0<at.%N{\le}23.3$) thus produced are identified as the super-saturated bee structure for the N content below 14.9 at.%N and the high temperature phase of the hcp structure above 19.4 at.%N. The atomic volume of Fe in the bcc phase is found to be smaller than that of the N-martensite reported in the literature. Magnetization at room temperature gradually decreases with increasing the N concentration in contrast to the enhancement reported for the bet nitrides. Neutron diffraction experiment also provide detailed information about the local structure surrounding the nitrogen atom. The coordination number of Fe atom around a nitrogen atom for the iron nitride containing 9.5 at.%N turns out to be 3.9 atoms.

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Spermatogenic index and hormonal profile in the rats received chromatographic fractions of ethanol extract of Crotalaria juncea L. seeds

  • Malashetty, Vijaykumar B.;Patil, Saraswati B.
    • Advances in Traditional Medicine
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    • v.6 no.2
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    • pp.86-95
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    • 2006
  • The ethanol extract of the Crotalaria juncea seeds, which showed promising antispermatogenic and antiandrogenic activities in albino mice, was taken up further for the isolation of the active fractions present in it. Two fractions that were obtained from thin layer chromatography were subjected for testing to know their antispermatogenic and antiandrogenic activities. After preliminary trials the fraction I showed maximum antifertility activity at the dose level of 200 mg/kg body weight when administered orally to the rats for 50 days. The fraction I was found to affect spermatogenesis as well as the endocrine functions of the testis as indicated by gravimetric, histopathological and biochemical changes. Further this fraction has caused degenerative changes in the seminiferous tubules and Leydig cells of the testis. The accessory reproductive organs like epididymis, seminal vesicles, vas deferens, prostrate, Cowper's gland and Levator Ani muscle showed significant malfunction. Cauda epididymal sperm count and sperm motility were reduced significantly. The treatment has also resulted in increase in the cholesterol level and alkaline phosphatase activity, and decrease in protein, glycogen, sialic acid contents and acid phosphatase activity in testis. It is noteworthy that RIA studies have shown significant reduction in serum FSH, LH and testosterone. Scanning electron microscopic observations revealed abnormalities in sperm structure.

Antispermatogenic and antiandrogenic activities of various extracts of Melia azedarach Linn. seeds in albino rats

  • Patil, Sharanabasappa A.;Malashetty, Vijaykumar B.;Patil, Saraswati B.
    • Advances in Traditional Medicine
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    • v.3 no.3
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    • pp.133-140
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    • 2003
  • Petroleum ether, chloroform and ethanol extracts of the seeds of Melia azedarach Linn. administered orally to male rats at the dose level of 25 mg/100 g body weight for 48 days showed antispermatogenic activity, as the number of spermatocytes, spermatids and spermatozoa was decreased. The total cholesterol content was increased while protein and glycogen contents were decreased. The acid phosphatase content was also decreased while that of alkaline phosphatase increased. At the same time the weight of caput and cauda epididymis, prostate gland, seminal vesicle and Levator Ani muscle was decreased indicating its antiandrogenic property. Of the three extracts, the petroleum ether extract was more potent in its antispermatogenic and antiandrogenic activities and did not produce any sings of toxicity upto a dose of 25 mg/100 g body weight oral administration. After subjecting it to preliminary phytochemical screening the petroleum ether extract showed positive tests for steroids and saponins.