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Surface Characteristics of Type II Anodized Ti-6Al-4V Alloy for Biomedical Applications

  • Lee, Su-Won;Jeong, Tae-Gon;Yang, Jae-Ung;Jeong, Jae-Yeong;Park, Gwang-Min;Jeong, Yong-Hun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2017.05a
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    • pp.77-77
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    • 2017
  • Titanium and its alloys offer attractive properties in a variety of applications. These are widely used for the field of biomedical implants because of its good biocompatibility and high corrosion resistance. Titanium anodizing is often used in the metal finishing of products, especially those can be used in the medical devices with dense oxide surface. Based on SAE/AMS (Society of Automotive Engineers/Aerospace Material Specification) 2488D, it has the specification for industrial titanium anodizing that have three different types of titanium anodization as following: Type I is used as a coating for elevated temperature forming; Type II is used as an anti-galling coating without additional lubrication or as a pre-treatment for improving adherence of film lubricants; Type III is used as a treatment to produce a spectrum of surface colours on titanium. In this study, we have focused on Type II anodization for the medical (dental and orthopedic) application, the anodized surface was modified with gray color under alkaline electrolyte. The surface characteristics were analyzed with Focused Ion Beam (FIB), Scanning Electron Microscopy (SEM), surface roughness, Vickers hardness, three point bending test, biocompatibility, and corrosion (potentiodynamic) test. The Ti-6Al-4V alloy was used for specimen, the anodizing procedure was conducted in alkaline solution (NaOH based, pH>13). Applied voltage was range between 20 V to 40 V until the ampere to be zero. As results, the surface characteristics of anodic oxide layer were analyzed with SEM, the dissecting layer was fabricated with FIB method prior to analyze surface. The surface roughness was measured by arithmetic mean deviation of the roughness profile (Ra). The Vickers hardness was obtained with Vickers hardness tester, indentation was repeated for 5 times on each sample, and the three point bending property was verified by yield load values. In order to determine the corrosion resistance for the corrosion rate, the potentiodynamic test was performed for each specimen. The biological safety assessment was analyzed by cytotoxic and pyrogen test. Through FIB feature of anodic surfaces, the thickness of oxide layer was 1.1 um. The surface roughness, Vickers hardness, bending yield, and corrosion resistance of the anodized specimen were shown higher value than those of non-treated specimen. Also we could verify that there was no significant issues from cytotoxicity and pyrogen test.

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Effects of Miling System on Gouda Cheese Characteristics made from Farmstead Milk-processing Plant (착유방식이 목장형 유가공으로 제조된 고다치즈의 품질 특성에 미치는 영향)

  • Lee, Jin-Sung;Moon, Ju Yeon;Nam, Ki-Taeg;Park, Seong-Min;Park, Seung-Yong;Jung, Mun Yhung;Son, Yong-Suk
    • Journal of Dairy Science and Biotechnology
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    • v.34 no.4
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    • pp.245-254
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    • 2016
  • This investigation was carried out to study effects of different milking systems on the characteristics of Gouda cheese produced at farmstead milk-processing plants. In the first study, raw milk was collected from automatic milking system and conventional milking system farms, and Gouda cheeses were prepared under the same conditions. After 6 months of aging, the chemical composition was analyzed and free fatty acid (FFA) analysis and sensory evaluation were carried out on the products. In the second study, Gouda cheese samples were collected from seven farmstead milk-processing plants and the chemical composition and texture profile analysis were evaluated. No significant differences were found in the chemical composition of Gouda cheese according to different milking systems or different farms except crude ash. FFA analysis showed significant differences among farms, but sensory evaluation showed no significant differences. No significant differences were observed in FFA content and sensory assessment of different milking systems. Texture profile analysis revealed that there were significant differences in each cheese made at different farm plants, but there were no differences when different milking systems were used.

Meaning Analysis (의미 분석)

  • Lee, Gun-Won
    • Annual Conference on Human and Language Technology
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    • 2000.10d
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    • pp.419-423
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    • 2000
  • 성공적인 의사소통의 경우에 성(性)이, 이(理)와 명(命)으로 나타난 것이 같다. 진리(aletheia)가, 언어(logos)와 운명(moira)으로 나타난 것들이 일치하는 것이 성공적인 언화행위가 된다. 측정대상(melos)과 본체(ousia)가 구분되는 것은 언어와 운명의 괴리가 있을 수가 있기 때문이다. 체계적인 언어처리의 지식기반을 측정대상에 한정한다. (1) 철학의 시작은 더 옳은 언어표현의 정의(definition)로 이전의 잘못 사용된 언어처리를 대체시키는 것으로 소크라테스는 보았다. [R. Crossman] (2) 잘못을 지적하는 등에(Tabanidae)의 역할과 옮은 지식의 상기를 돕는 산파법(maieutics)이 소크라테스의 의미분석의 방법이다. [R. Crossman] (3) 언어를 통하여 진리를 추구한다는 입장(via language)애서 한 언어표현이 그 진리의 운명으로 나타남과 어긋날 때, 운명을 택하는 것은 조화 보다 더 안정의 우위를 인정하는 논리적인 입장으로 합리성 보다 실용(pragma)의 우위를 인정하는 것이다. [W. Quine] (4) 공동체의 공통규범의 추구는 그 언어 속의 공통의 형식 또는 법칙의 추구에 기초하는 것이 자연스럽다. 여기에서 그 언어사용은 그 기저의 법칙(underlying rule)에 개입한다는 입장에 기초한다. [J. Searle] (5) 진리의 언어표현과 운명적인 사태들 사이의 괴리를 처리하기 위하여 체계적인 언어표현의 대상(The Young Tableaux)과 실제(The continuum)의 구분을 수용한다. [AMS(2000)] 언어표현의 대상은 나타난 것(현)(顯)이고 실제에는 나타나지 않은 것도 있다. 이천(伊川), 명도(明道)] (6) 이 나타난 것과 나타나지 않은 것에 간격이 없다는 것(현미무간)(顯微無間)은 그 의사소통이 성공적인 것이라는 것을 말한다. 따라서 그 언어의 표현완전성(functional completeness)은 언화행위가 성공적이라는 것이다.[J. Searle] (7) 수로 쓰인 것(상수)(象數)과 시로 쓰인 것(의리)(義理)이 하나인 것은 그 나타난 것과 나타나지 않은 것들 사이에 어떠한 들도 없음을 말한다. [(성중영)(成中英)] (8) 공통의 규범의 공통성 속에 규범적인 측면이 벌써 있다. 공통성에서 개인적이 아닌 공적인 규범으로의 전이는 규범, 가치, 규칙, 과정, 제도로의 전이라고 본다. [C. Morrison] (9) 우리의 언어사용에 신비적인 요소를 부인할 수가 없다. 넓은 의미의 발화의미(utterance meaning) 속에 신비적인 요소나 애정표시도 수용된다. 의미분석은 지금 한글을 연구하고, 그 결과에 의존하여서 우리의 실제의 생활에 사용하는 $\ulcorner$한국어사전$\lrcorner$ 등을 만드는 과정에서, 어떤 의미에서 실험되었다고 말할 수가 있는 언어과학의 연구의 결과에 의존하여서 수행되는 철학적인 작업이다. 여기에서는 하나의 철학적인 연구의 시작으로 받아들여지는 이 의미분석의 문제를 반성하여 본다.

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Altitude training as a powerful corrective intervention in correctin insulin resistance

  • Chen, Shu-Man;Kuo, Chia-Hua
    • Korean Journal of Exercise Nutrition
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    • v.16 no.2
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    • pp.65-71
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    • 2012
  • Oxygen is the final acceptor of electron transport from fat and carbohydrate oxidation, which is the rate-limiting factor for cellular ATP production. Under altitude hypoxia condition, energy reliance on anaerobic glycolysis increases to compensate for the shortfall caused by reduced fatty acid oxidation [1]. Therefore, training at altitude is expected to strongly influence the human metabolic system, and has the potential to be designed as a non-pharmacological or recreational intervention regimen for correcting diabetes or related metabolic problems. However, most people cannot accommodate high altitude exposure above 4500 M due to acute mountain sickness (AMS) and insulin resistance corresponding to a increased levels of the stress hormones cortisol and catecholamine [2]. Thus, less stringent conditions were evaluated to determine whether glucose tolerance and insulin sensitivity could be improved by moderate altitude exposure (below 4000 M). In 2003, we and another group in Austria reported that short-term moderate altitude exposure plus endurance-related physical activity significantly improves glucose tolerance (not fasting glucose) in humans [3,4], which is associated with the improvement in the whole-body insulin sensitivity [5]. With daily hiking at an altitude of approximately 4000 M, glucose tolerance can still be improved but fasting glucose was slightly elevated. Individuals vary widely in their response to altitude challenge. In particular, the improvement in glucose tolerance and insulin sensitivity by prolonged altitude hiking activity is not apparent in those individuals with low baseline DHEA-S concentration [6]. In addition, hematopoietic adaptation against altitude hypoxia can also be impaired in individuals with low DHEA-S. In short-lived mammals like rodents, the DHEA-S level is barely detectable since their adrenal cortex does not appear to produce this steroid [7]. In this model, exercise training recovery under prolonged hypoxia exposure (14-15% oxygen, 8 h per day for 6 weeks) can still improve insulin sensitivity, secondary to an effective suppression of adiposity [8]. Genetically obese rats exhibit hyperinsulinemia (sign of insulin resistance) with up-regulated baseline levels of AMP-activated protein kinase and AS160 phosphorylation in skeletal muscle compared to lean rats. After prolonged hypoxia training, this abnormality can be reversed concomitant with an approximately 50% increase in GLUT4 protein expression. Additionally, prolonged moderate hypoxia training results in decreased diffusion distance of muscle fiber (reduced cross-sectional area) without affecting muscle weight. In humans, moderate hypoxia increases postprandial blood distribution towards skeletal muscle during a training recovery. This physiological response plays a role in the redistribution of fuel storage among important energy storage sites and may explain its potent effect on changing body composition. Conclusion: Prolonged moderate altitude hypoxia (rangingfrom 1700 to 2400 M), but not acute high attitude hypoxia (above 4000 M), can effectively improve insulin sensitivity and glucose tolerance for humans and antagonizes the obese phenotype in animals with a genetic defect. In humans, the magnitude of the improvementvaries widely and correlates with baseline plasma DHEA-S levels. Compared to training at sea-level, training at altitude effectively decreases fat mass in parallel with increased muscle mass. This change may be associated with increased perfusion of insulin and fuel towards skeletal muscle that favors muscle competing postprandial fuel in circulation against adipose tissues.

Seismic Performance Evaluation of Unreinforced and ECC-jacketed Masonry Fences using Shaking Table Test (진동대실험을 사용한 비보강 및 ECC 자켓 보강 조적담장의 내진성능평가)

  • Yonghun Lee;Jinwoo Kim;Jae-Hwan Kim;Tae-Sung Eom;Sang-Hyun Lee
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.27 no.6
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    • pp.182-192
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    • 2023
  • In this study, the efficacy of Engineered Cementitious Composite(ECC) jacket for masonry fences subjected to lateral dynamic load was experimentally verified through a shaking table test, comparing it with the performance of an unreinforced masonry(URM) fence. Firstly, dominant frequencies, modal damping ratios and deformed shapes were identified through an impact hammer test. URM and ECC-strengthened fences with heights of 940mm and 970mm had natural frequencies of 6.4 and 35.3Hz, and first modal damping ratios of 7.0 and 5.3%, respectively. Secondly, a shaking table test was conducted in the out-of-plane direction, applying a historical earthquake, El Centro(1940) scaled from 25 to 300%. For the URM fence, flexural cracking occurred at the interface of brick and mortar joint(i.e., bed joint) at the ground motion scaled to 50%, and out-of-plane overturning failure followed during the subsequent test conducted at the ground motion scaled to 30%. On the other hand, the ECC-jacketed fence showed a robust performance without any crack or damage until the ground motion scaled to 300%. Finally, the base shear forces exerted upon the URM and ECC-jacketed fences by the ground motions scaled to 25~300% were evaluated and compared with the ones calculated according to the design code. In contrast to the collapse risk of the URM fence at the ground motion of 1,000-year return period, the ECC-jacketed fence was estimated to remain safe up to the 4,800-year return period ground motion.

The Calendar Date of Pottery with Ring-Rim -Appearance Date of the Slim Bronze Dagger Culture and Ironware- (점토대토기의 실연대 -세형동검문화의 성립과 철기의 출현연대-)

  • Lee, Chang Hee
    • Korean Journal of Heritage: History & Science
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    • v.43 no.3
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    • pp.48-101
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    • 2010
  • This paper estimated the calendar date of pottery with ring-rim(粘土帶土器) with the radiocarbon dating. This was based on archaeological facts with comparing line relations and radiocarbon dates of Yayoi pottery(彌生土器). As a result, I understood that pottery with circle ring-rim(圓形粘土帶土器) appeared in BC 6c, pottery with triangle ringrim(三角形粘土帶土器) appeared at the time in BC 300 . Based on the calendar date and aspect of ironware and pottery in grave, I kept in BC 4c with appearance date of ironware. And I kept in BC 5c with appearance date of the slim bronze dagger culture. Korea and Japan common chronological order were built for the first time based on radiocarbon dates, line relations of pottery with ring-rim and Yayoi pottery. This is the calendar date to date back approximately 100~300 years from the existing the calendar date. Current periodization does not match in the calendar date when I built it newly. Therefore I suggested it as follows. Early iron age is from the first~middle part BC 4c to BC 100. And the latter half of Bronze age is from BC 6c to the front appearance of ironware. Then Songguk-ri type(松菊里式) becomes staudard type of pottery in the middle stage of Bronze age.

Scientific Analysis and Conservation Treatment on the Buddhist Scriptures of Paper Relics Excavated from Sum Tolgoi, Mongolia (몽골 숨 톨고이 출토 지류 유물의 과학적 분석 및 보존처리)

  • Bae, Su Bin;Yang, Min Jeong;Kwon, Yun Mi;Yoo, Ji Hyun;Jeong, Hee Won
    • Journal of Conservation Science
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    • v.37 no.6
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    • pp.723-737
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    • 2021
  • This study analyzed the composition and structure of materials with Buddhist paper scriptures excavated from architectural sites in 'Sum Tolgoi' of the 17th century and carried out conservation treatment base on the result of the analysis. The scriptures were covered in dust and foreign sub stances, and were so crumpled that it was impossible to identify the form. The damage, loss, and discoloration have been identified. Buddhist scriptures written in Tibetan used indigo and ink sticks on paper as a result of UV-Vis analysis, and ink sticks as black character materials from scriptures written ancient Mongolian. SEM-EDS and Micro-XRF analyses revealed that the outlines were drawn with red lines using a mix of Minium (Pb3O4) and Cinnabar (HgS), or Cinnabar (HgS) alone, and the contents of the scriptures were written with silver paint. Silver chloride (AgCl) and Calcium (Ca) were identified in the silver paint component of the characters, while Calcium and Orpiment (As2S3) were identified in the yellow lines. Concerning the paper ground, Buddhist scriptures written in ancient Mongolian were characterized by herbal plant fiber and bast fiber, and those written in Tibetan, by bast fiber. Radiocarbon dating indicates that the paper for the scriptures was produced between the 15th and 17th centuries. Conservation treatment of the scriptures was carried out based on the experiment on the production of pre-coated paper and how to coat that to prevent the second damage due to the deformation and fragility of the excavated paper. The scriptures were preserved and mounted, and a neutral box was made to identify the contents of the scriptures recorded on both sides after the treatment. This conservation treatment is the result of a study that applied new conservation treatment materials and methods according to the principle of conservation treatment reversibility.

Applications of Radiocarbon Isotope Ratios in Environmental Sciences in South Korea (방사성탄소동위원소비 분석을 적용한 우리나라 환경과학 연구)

  • Neung-Hwan Oh;Ji-Yeon Cha
    • Korean Journal of Ecology and Environment
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    • v.56 no.4
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    • pp.281-302
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    • 2023
  • Carbon is not only an essential element for life but also a key player in climate change. The radiocarbon (14C) analysis using accelerator mass spectrometry (AMS) is a powerful tool not only to understand the carbon cycle but also to track pollutants derived from fossil carbon, which have a distinct radiocarbon isotope ratio (Δ14C). Many studies have reported Δ14C of carbon compounds in streams, rivers, rain, snow, throughfall, fine particulate matter (PM2.5), and wastewater treatment plant effluents in South Korea, which are reviewed in this manuscript. In summary, (1) stream and river carbon in South Korea are largely derived from the chemical weathering of soils and rocks, and organic compounds in plants and soils, strongly influenced by precipitation, wastewater treatment effluents, agricultural land use, soil water, and groundwater. (2) Unprecedentedly high Δ14C of precipitation during winter has been reported, which can directly and indirectly influence stream and river carbon. Although we cannot exclude the possibility of local contamination sources of high Δ14C, the results suggest that stream dissolved organic carbon could be older than previously thought, warranting future studies. (3) The 14C analysis has also been applied to quantify the sources of forest throughfall and PM2.5, providing new insights. The 14C data on a variety of ecosystems will be valuable not only to track the pollutants derived from fossil carbon but also to improve our understanding of climate change and provide solutions.