• Title/Summary/Keyword: AM1

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Development of the Central Nervous System in the Wolf Spider Arctosa kwangreungensis (Araneae: Lycosidae) (광릉늑대거미(Arctosa kwangreungensis) 중추신경계 발생에 관한 연구)

  • Yang, Sung-Chan;Moon, Myung-Jin
    • Applied Microscopy
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    • v.42 no.2
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    • pp.77-86
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    • 2012
  • The morphological and histologic differentiation of the central nervous system (CNS) in the wolf spider Arctosa kwangreungensis with respect to postembryonic development are studied using light and scanning electron microscopes. The organization of CNS which consisted of supraesophageal ganglion (SpG) and subesophageal ganglion (SbG) are established prior to the postembryo stage. The brain of first instar spiderling after a molt of the postembryo is also made up of supraesophageal ganglion and subesophageal ganglion. Although development of the optic nerve and optic lobe in SpG are not completed during the postembryoic stage, completion of whole neural system resemble to that of adult are established during the second instar stage. In particular, optic gangalion is developed from the undifferentiated cell clusters of the SpG, moreover four pairs of appendage ganglia and another pairs of abdominal ganglia are produced from the SbG. Nerve cells of the most developing stages are composed of typical monopolar neur1ons, and total three types of neurons can be identified through the histological and morphological basis of present study. These cell clusters are differentiated into neurons and grow dendritic fibers according to further development of the CNS.

Synthesis and Photovoltaic Properties of Copolymers with Fluorinated Quinoxaline and Fluorene Moiety (Fluorine이 도입된 Quinoxaline과 Fluorene 골격을 가진 고분자의 합성 및 특성분석)

  • Song, Suhee;Choi, Hyo Il;Shin, In Soo;Park, Seong Soo;Lee, Gun Dae;Park, Sung Heum;Jin, Youngeup
    • Applied Chemistry for Engineering
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    • v.27 no.5
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    • pp.467-471
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    • 2016
  • New electron deficient moiety, 6,7-difluoro-2,3-dihexylquinoxaline, was developed for the push-pull type copolymer for organic photovoltaics (OPVs). The PFDTQxF with lower HOMO energy level was synthesized using fluorene and 6,7-difluoro- 2,3-dihexylquinoxaline by Suzuki polymerization. The PFDTQxF thin film shows two absorption peaks at 368 and 493 nm. The HOMO and LUMO energy levels of PFDTQxF are calculated -5.55 and -3.91 eV, respectively. The device comprising PFDTQxF showed a $V_{OC}$ value of 0.47 V, a $J_{SC}$ value of $4.48mA/cm^2$, and a FF of 0.32, which yielded PCE of 0.78%, under the illumination of AM 1.5.

Antioxidative and Protective Effects of Haeganjeon Extract on Oxidative Damage of Hepatocytes (해간전(解肝煎)의 항산화(抗酸化) 활성(活性) 및 간세포(肝細胞)의 산화적(酸化的) 손상(損傷)에 대한 보호효과(保護效果))

  • Ahn Byung-Tae;Kim Jong-Dae;Moon Jin-Young
    • Herbal Formula Science
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    • v.10 no.2
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    • pp.127-141
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    • 2002
  • Objectives: Haeganjeon(HGJ) has been used for the treatment of liver disease in traditional medicine. The present study was carried out to evaluate the antioxidant and protective effects of HGJ extract on oxidative damage of hepatocytes by tert-butyl hydroperoxide(t-BHP). Methods: In the linoleic acid water-alcohol system, the levels of lipid peroxide(LPO) were determined by TBA method. The scavenging effect of HGJ on ${\alpha},{\alpha}-diphenyl-{\beta}-picrylhydrazyl$(DPPH) radical was determined according to the method of Hatano. In the Fenton system(ferrous ion reaction with hydrogen peroxide), the levels of hydroxyl radical induced LPO in rat liver homogenate were determined according to the method of TBA. Inhibitory effect of HGJ on superoxide generation was measured by xanthine-xanthine oxidase system. In order to evaluate antioxidative activity of HGJ in the liver cell, cultured normal rat liver cells(Ac2F) were prepared and incubated with or without HGJ. After 18hr, cells placed in DMEM medium without serum, and then incubated with 1mM tert-butyl hydroperoxide(t-BHP) for 2hrs. Viable cells were detected by MTT assay. Conclusions: In the linoleic acid autoxidation system, HGJ extract significantly inhibited the time course of the lipid peroxidation. These effects were similar to those of BHA HGJ extracts showed about 70% scavenging effect on DPPH radical. And HGJ extract inhibited the lipid peroxide formation in rat liver homogenate induced by hydroxyl radical derived from Fenton system. In addition, HGJ extract protected the cell death induced by t-BHP and significantly increased cell viability in the normal rat liver cell. These result indicated that HGJ extract might playa protective role against oxidative hepatic cell injury by means of free radical scavenger.

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A Study n the Application of Career Education Materials in Middle School Home Economics Instruction (진로 교육 자료의 중학교 가정과 수업에의 적용 연구)

  • 강인애;윤인경
    • Journal of Korean Home Economics Education Association
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    • v.5 no.1
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    • pp.113-120
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    • 1993
  • This study in order to seek for a more effective teaching method, I am to propose a measure that the career education material for female middle school students a program produced already could be applicable on the class and to understand the efficiency by examining practically it to the student. The research method was to make up a questionnaire and gaze two kinds of educational effect. The procedure was that, after surveying the general features in order to help them known their consciousness on the career education Researcher practiced common theorectical teaching on comparative class and moduling teaching on comparative class through making a guiding data. Then Researcher analysed the changing o consciousness on career, knowledge on kinds and numbers of jobs, and the results and rate of interest in the teaching with persentage and t-test. The results are as followed; First, on the consciousness on career, both group showed little change on their wishful job between before and after teaching. On the purpose to get a job, consciousness on work and job, and fixed idea of job on gender, there were some changes, but both groups had few defferences in the changing rate. Second on the consciousness on work and job experimental group recognized the variety of job more than comparative group and wrote more hind of job. Third on the evaluating result, the record of experimental group was higher. Fourth, on the rate of interesting in learning the rate of experimental group was higher. As observed the class applied by the module of female career education is effective, since experimental group showed more consciousness on work and job, evaluation of record after teaching and the rat of interesting in learning, through there was no difference in the consciousness of the career.

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The influence of systemically administered oxytocin on the implant-bone interface area: an experimental study in the rabbit

  • Cho, Sung-Am;Park, Sang-Hun;Cho, Jin-Hyun
    • The Journal of Advanced Prosthodontics
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    • v.6 no.6
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    • pp.505-511
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    • 2014
  • PURPOSE. The purpose of this study was to assess the effect of systemically administered oxytocin (OT) on the implant-bone interface by using histomorphometric analysis and the removal torque test. MATERIALS AND METHODS. A total of 10 adult, New Zealand white, female rabbits were used in this experiment. We placed 2 implants (CSM; CSM Implant, Daegu, South Korea) in each distal femoral metaphysis on both the right and left sides; the implants on both sides were placed 10 mm apart. In each rabbit, 1 implant was prepared for histomorphometric analysis and the other 3 were prepared for the removal torque test (RT). The animals received intramuscular injections of either saline (control group; 0.15 M NaCl) or OT (experimental group; $200{\mu}g/rabbit$). The injections were initiated on Day 3 following the implant surgery and were continued for 4 subsequent weeks; the injections were administered twice per day (at a 12-h interval), for 2 days per week. RESULTS. While no statistically significant difference was observed between the two groups (P=.787), the control group had stronger removal torque values. The serum OT concentration (ELISA value) was higher in the OT-treated group, although no statistically significant difference was found. Further, the histomorphometric parameter (bone-to-implant contact [BIC], inter-thread bone, and peri-implant bone) values were higher in the experimental group, but the differences were not significant. CONCLUSION. We postulate that OT supplementation via intramuscular injection weakly contributes to the bone response at the implant-bone interface in rabbits. Therefore, higher concentrations or more frequent administration of OT may be required for a greater bone response to the implant. Further studies analyzing these aspects are needed.

A Study on Development of an Anti-Rolling System for the Ship Stability Improvement (선박안정성 향상을 위한 횡동요 방지 장치 개발에 관한 연구)

  • Kim, Young-Bok;Lee, Kwon-Soon;Kim, Jun-Hyo;Chae, Gyu-Hoon
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.11 no.1 s.22
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    • pp.23-28
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    • 2005
  • We have investigated the usefulness cf active stabilizing system to reduce ship rolling under disturbances, using varying reaction cf the flaps. In the proposed anti-rolling system for a ship, the flaps as the actuator are installed on the stem to reject rolling motion induced by disturbances like wave. The action induced by flaps which depends on power of disturbances am take the ship balance. Especially, in this study we identify the controlled system under the undefined system structure using spectral analysis and experimental studies. Based on these informations, we design the controller to evaluate the usefulness of the proposed system.

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Evaluating the Catalytic Effects of Carbon Materials on the Photocatalytic Reduction and Oxidation Reactions of TiO2

  • Khan, Gulzar;Kim, Young Kwang;Choi, Sung Kyu;Han, Dong Suk;Abdel-Wahab, Ahmed;Park, Hyunwoong
    • Bulletin of the Korean Chemical Society
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    • v.34 no.4
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    • pp.1137-1144
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    • 2013
  • $TiO_2$ composites with seven different carbon materials (activated carbons, graphite, carbon fibers, single-walled carbon nanotubes, multi-walled carbon nanotubes, graphene oxides, and reduced graphene oxides) that are virgin or treated with nitric acid are prepared through an evaporation method. The photocatalytic activities of the as-prepared samples are evaluated in terms of $H_2$ production from aqueous methanol solution (photo-catalytic reduction: PCR) and degradation of aqueous pollutants (phenol, methylene blue, and rhodamine B) (photocatalytic oxidation: PCO) under AM 1.5-light irradiation. Despite varying effects depending on the kinds of carbon materials and their surface treatment, composites typically show enhanced PCR activity with maximum 50 times higher $H_2$ production as compared to bare $TiO_2$. Conversely, the carbon-induced synergy effects on PCO activities are insignificant for all three substrates. Colorimetric quantification of hydroxyl radicals supports the absence of carbon effects. However, platinum deposition on the binary composites displays the enhanced effect on both PCR and PCO reactions. These differing effects of carbon materials on PCR and PCO reactions of $TiO_2$ are discussed in terms of physicochemical properties of carbon materials, coupling states of $TiO_2$/carbon composites, interfacial charge transfers. Various surface characterizations of composites (UV-Vis diffuse reflectance, SEM, FTIR, surface area, electrical conductivity, and photoluminescence) are performed to gain insight on their photocatalytic redox behaviors.

Dohaekseungkitang extract induced apoptosis in Human Cervical carcinoma HeLa cells (도핵승기탕(桃核承氣湯) 자궁경부암세포(子宮經部癌細胞)(HeLa cell)의 apoptosis에 미치는 영향(影響))

  • Kang, Yong-Goo;Ahn, Kyu-Hwan;Kong, Bok-Cheul;Kim, Song-Baeg;Cho, Han-Baek
    • The Journal of Korean Obstetrics and Gynecology
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    • v.19 no.2
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    • pp.77-91
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    • 2006
  • Purpose : To address the ability of Dohaekseungkitang (DST: a commonly used herb formulation in Korea, Japan and China to have anti-cancer effect on cervical carcinoma), we investigated the effects of DST on programmed cell death (apoptosis) in HeLa human cervical carcinoma cells. Methods : We cultured HeLa cell which is human metrocarcinoma cell in D-MEM included 10% fetal bovine serum(Hyclone Laboratories) below $37^{\circ}C$, 5% CO2. Then we observed apoptosis of log phage cell which is changed cultivation liquid 24 Hours periodically. Results : After the treatment of DST for 48 hours, apoptosis occurred in a dose-dependent manner. In this study, we have shown that DST induces calpain and the associated caspase-8 and -9 activations. Apoptosis was prevented by pre-incubation of the cells with the calcium cHeLator-BAPTA-AM, calcium channel blocker-Nif edipine or Ryonidine agonist-Ryonidine peptide, implicating calcium in the apoptotic process. Ubiquitous calpains (mu- and m-calpain) have been repeatedly implicated in apoptosis, especially in calcium-related apoptosis. However this study showed 1hat either calpain inhibitor-calpastin or caspase-3 inhibitor-DEVD- did not blocked the herb formulation-induced apoptosis in HeLa human cervical carcinoma cells. D ST initiates a cell death pathway that is partially dependent of caspases. DST-induced apoptosis requires caspase-independent mechanism. Conclusion : We conclude that DST-induced calpain activation triggers the intrinsic apoptotic pathway in which caspase-independent mechanism is also involved.

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Bibliographic Study on the Interrelation between Dong Shi' Acupuncture and Twelve Regular Channels (동씨침법(董氏針法)과 십이정경(十二正經)의 상관성(相關性)에 관(觀)한 연구(硏究))

  • Jang Jin-Yo;Kim Kyung-Sik;Sohn In-Chul
    • Korean Journal of Acupuncture
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    • v.19 no.1
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    • pp.107-130
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    • 2002
  • In the clinics of traditional medicine, various acupuncture methods, that is Sa-Am' acupuncture, scalp acupuncture, auricular acupuncture and Dong-Shi' acupuncture, have been introduced and increased gradually to treat the diseases. In this bibliographic study, we examined the interrelation between the Dong Shi' acupuncture and 12 regular channels. The theoretical origination of Dong Shi' acupuncture and 12 regular channels was applied from Yin and Yang, Five Element, State of Viscera and so on. As the treatment using by 12 regular channels have used to 'regulating Qi and Treating Shin (調氣治神)', Dong Shi' acupuncture have used to the itself defense mechanism and relative balance of human beings. Also, these methods have the same rules that was selected to the opposing needling (巨刺) of remote point selection, however, Ah-Shi' points (阿是穴) were not used for the selection. Of Dong-Shi' acu-points, there were many ones which have the same location as the acupoints of regular channels. However, these one was renamed according to the new characteristics and therapeutics found by Dong Shi. Dong Shi' acupuncture has divided human body to the 12 areas but not considered to the concept of a mutual connection of human being body. The needling manipulation methods were vary at the regular channels, but Dong Shi' acupuncture did not use the traditional manipulation method except for supplementary Dong-Qi acupuncture, To-Ma acupuncture and To-In acupuncture. From these study, we found that the Dong-Shi' acupuncture have something in common with 12 regular channels, although the Dong-Shi' acupuncture was not based on the theory of 12 regular channels.

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Effects of Storage Temperatures and Periods on the Direct Somatic Embryogenesis in Rehmannia glutinosa Liboschitz and Scrophularia buergeriana Miquel (지황과 현삼에서 배양전 저장 온도와 기간이 직접 체세포배 형성에 미치는 영향)

  • Park, Ju-Hyun;Song, Ji-Sook;Ohk, Hyun-Choong;Lim, Wan-Sang;Chae, Young-Am
    • Korean Journal of Medicinal Crop Science
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    • v.7 no.1
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    • pp.7-10
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    • 1999
  • The effects of storage temperature and periods as pretreatments on direct somatic embryogenesis or shoot development in liquid culture of leaves, stems and petioles of Rehmannia glutinosa and Scrophularia buergeriana were investigated. Proper storage Temperature for Rehmannia glutinosa was $8^{\circ}C$ and the leaf stock could be stored up to 12 weeks. In Scrophularia buergerjana. shoots were developed from the 20 week-stored petiole and stem at $8^{\circ}C$. In general, $8^{\circ}C$ was considered the most effective storage temperature in terms of storage cost.

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