• Title/Summary/Keyword: AM to AM

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Effect of Sodium Taurodeoxycholate on Biliary Excretion of Amaranth as an Anionic Model Drug in Rats (음이온 모델 화합물 아마란스의 담즙배설에 미치는 타우로데옥시콜레이트의 영향)

  • Shim, Chang-Koo;Chung, Suk-Jae
    • Journal of Pharmaceutical Investigation
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    • v.16 no.3
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    • pp.110-117
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    • 1986
  • Plasma disappearance of amaranth (AM), a model compound of organic anionic drugs, was retarded by intravenous infusion of taurodeoxycholate (TDC), a representative bile acid, in the rat. Biliary excretion accounted for 30-60% of the systemic excretion of AM. AM seemed to be metabolised in the hepatocyte to form a compound that is excreted more rapidly into the bile than AM itself, considering apparent biliary clearance, $CL_{bil}$, is much larger than systemic clearance, $CL_s$. Decrease in $CL_{bil}$ by TDC infusion might be due to elevated plasma level rather than decreased biliary excretion of AM. Decreased distribution or urinary excretion of AM by TDC was supposed to be one of the probable reasons of elevated plasma level. Competitive inhibition between AM and TDC on tissue distribution and urinary excretion might explain the mechanism. The effect of TDC on the $CL_{bil}$ of methylene blue, a cationic dye, was quite different from that of AM, as reported previously by us. More intensive study would be necessary to elucidate the difference of biliary excretion between organic anions and cations.

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Immunobiological Studies on Route of Administration of Amygdalin (아미그달린의 투여경로에 따른 면역생물학적 연구)

  • Kim, Joung-Hoon;Kang, Tae-Wook;Park, Chan-Bong;Cha, Kwang-Jae;Ahn, Young-Keun
    • YAKHAK HOEJI
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    • v.40 no.2
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    • pp.202-211
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    • 1996
  • Experiments were performed on male Sprague-Dawley rats to investigate the immunobiological effects on route of administration of amygdalin(AM). Rats were administered orally at 12.5, 25, or 50mg/kg/day of AM or injected wtih 25,50, or 100mg/kg/day of AM intravenously for 2 weeks. Rats were immunized and challenged with sheep red blood cells(SRBC). The results of this study were summarized as follows;(1) In oral administration of AM, body weight gains were significantly increased by 50mg/kg AM as compared with controls, the relative weights of liver and thymus also were significantly increased by 12.5 and 25mg/kg AM. However, 2-mercaptoethanol-resistant hemagglutination titier (2-MER HA), Plaque forming cells (PFC) and rosette forming cells (RFC) were non-dose dependently decreased. Phagocytic activity and delayed-type hypersensitivity (DTH) reaction also were significantly decreased by 50mg/kg AM. (2) In intravenous injection of AM, body weight gains, hemagglutination titer (HA), 2MER-HA, DTH reaction, PFC, RFC and circulating leukocytes were not influenced by AM. However, the relative weights of liver, spleen and thymus were significantly enhanced 100mg/kg AM. These results indicated that oral administration of AM non-dose dependently suppresses humoral and cell-mediated immunity in SD rats, and that intravenous injection of AM is unaffected humoral and cell-mediated immunity, however, the high dose of it significantly enhances phagocytic activity.

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Mutual Separation of Am(III) and Eu(III) by Solvent Extraction with Cyanex 301 (Cyanex 301에 의한 Am(III)과 Eu(III)의 상호분리)

  • Yang, Han-Beom;Lim, Jae-Gwan;Lee, Eil-Hee;Yoo, Jae-Hyung
    • Applied Chemistry for Engineering
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    • v.10 no.1
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    • pp.143-147
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    • 1999
  • The present paper describes the solvent extraction behaviors and the mutual separation of Am and Eu by sulphur bearing Cyanex 301 acidic extractant in sodium nitrate solutions. Original Cyanex 301 was not able to separate the Am and Eu because of their similar extraction behaviors. The saponification of commercial Cyanex 301 was performed by small amounts of 8 M NaOH solutions and saponified Cyanex 301 was able to separate of Am from Eu with high selectivity in sodium nitrate aqueous solution. The separation factors ($SF_{Am/Eu}$) were increased with saponified ratio of commercial Cyanex 301, pH of sodium nitrate solution and initial concentration of Eu. To obtain the homogeneous saponified Cyanex 301, heterogeneous saponified Cyanex 301 was treated with addition of octyl alcohol or filtration. The observed $SF_{Am/Eu}$ was 32.3 for the former and 930 for the latter. Finally, the stripping behaviors of Am and Eu were similar and stripping yields showed 96.1% for the 1 M $NaNO_3$(pH=1.3) and 99% for the mixture solution of 0.05 M DTPA and 1.5 M lactic acid.

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Effects of Arbuscular Mycorrhizae on Growth and Mineral Nutrient Contents in Trifoliate Orange Seedling (Arbuscular Mycorrhizae가 탱자 유묘의 생육과 무기양분 함량에 미치는 영향)

  • Oh, Hyun-Woo;Kim, Sang-Youb;Han, Hae-Ryong;Moon, Doo-Khil;Chung, Jong-Bae
    • Korean Journal of Environmental Agriculture
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    • v.17 no.2
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    • pp.182-188
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    • 1998
  • The effect of arbuscular mycorrhizae(AM) on the growth of trifoliate orange seeding were investigated in volcanic ash soil. Trifoliate orange is used as a root stock of citrus in Cheju island. Seedings innoculated with AM fungi were grown for 16 weeks in pots of various levels of fertilizer. Growth characteristics and mineral nutrient contents were measured and spores of AM fungi colonized were identified. Seventy % of the replicsted pots of seedings were colonized by AM in the treatment of high level fertilizer and additional phosphate (40g of 21-17-17 complex fertilizer and 50g of fused phosphate added to 50L of soil). In treatments of low levels fertilizer or without fused phosphate addition, the pots colonized were less than 20 %. Colonization of trifoliate seedings with AM fungi greatly increased the growth of seedings. Shoot length and weight of shoot and root positively regressed on AM colonization ratio. AM colonization caused higher concentrations of P, Cu and Mg in plant, and the relations were significant at 5 % level. Contents of N and Zn in plants also tended to increase, while that of Ca to decrease, with increasing colonization ratio. Four species of AM fungi - Glomus deserticola, G. rubiforme, G. vesiculiferum and Acaulospora sp, - were found in the soil where roots of trifoliate orange as an innoculation materials were collected. All of the 4 species were found in the inoculated pot soils after the seedling growth, indicating that these species can be colonized in trifoliate orange roots.

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AM-FM Decomposition and Estimation of Instantaneous Frequency and Instantaneous Amplitude of Speech Signals for Natural Human-robot Interaction (자연스런 인간-로봇 상호작용을 위한 음성 신호의 AM-FM 성분 분해 및 순간 주파수와 순간 진폭의 추정에 관한 연구)

  • Lee, He-Young
    • Speech Sciences
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    • v.12 no.4
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    • pp.53-70
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    • 2005
  • A Vowel of speech signals are multicomponent signals composed of AM-FM components whose instantaneous frequency and instantaneous amplitude are time-varying. The changes of emotion states cause the variation of the instantaneous frequencies and the instantaneous amplitudes of AM-FM components. Therefore, it is important to estimate exactly the instantaneous frequencies and the instantaneous amplitudes of AM-FM components for the extraction of key information representing emotion states and changes in speech signals. In tills paper, firstly a method decomposing speech signals into AM - FM components is addressed. Secondly, the fundamental frequency of vowel sound is estimated by the simple method based on the spectrogram. The estimate of the fundamental frequency is used for decomposing speech signals into AM-FM components. Thirdly, an estimation method is suggested for separation of the instantaneous frequencies and the instantaneous amplitudes of the decomposed AM - FM components, based on Hilbert transform and the demodulation property of the extended Fourier transform. The estimates of the instantaneous frequencies and the instantaneous amplitudes can be used for modification of the spectral distribution and smooth connection of two words in the speech synthesis systems based on a corpus.

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Evaluation of co- and Mutual Weparation for Actinide(III) and RE by a $(Zr-DEHPA)/n-dodecane-HNO_3$ Extraction System ($(Zr-DEHPA)/n-dodecane-HNO_3$ 금속함유 추출 계에 의한 악티나이드(III)및 RE의 공추출 및 상호 분리)

  • Lee, Eil-Hee;Lim, Jae-Kwan;Chung, Dong-Yong;Yang, Han-Beom;Kim, Kwang-Wook
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.5 no.2
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    • pp.123-132
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    • 2007
  • This study was performed to evaluate the co- and mutual separation for Am, Cm and RE elements from the simulated multi-component solution equivalent to real HLW level by a Zr-DEHPA(di-(2-ethylhexyl) phosphoric acid containing Zirconium)/$NDD(n-dodecane)-HNO_3$ extraction system. Zr-DEHPA was self-synthesized and the optimal condition of (15g/L Zr-1M DEHPA)/NDD-1M $HNO_3$ was selected taking into consideration of prevention of the third phase, and effects of concentration of DEHPA, nitric acid and impregnant amount of Zr on the co-extraction of Am, Cm and RE. In that condition, the extraction yields were 81% (Am), 85% (Cm), more than 80% (RE elements), 98% (Mo), 85% (Fe), 98% (U), 73% (Np), and less than 5% (other elements) so that the system developed for the co-extraction of Am-Cm/RE was proved to be available. For that, however, U, Np, Mo and Fe was elucidated to have to be removed in advance, and Zr inducing the third phase formation was found to be practically excluded. The co-extracted Am-Cm/RE were sequentially separated in an order of Am-Cm (stripping agent : 0.05 M DTPA-1M Lactic acid of pH 3.6)${\rightarrow}RE$ (stripping agent : 5M $HNO_3$), and then their separation factors were evaluated. At above conditions, Am of 65.4%, Cm of 63.9%, RE (except for Y) of more than 85% were stripped.

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Effects of Animal Excreta Classification and Nitrogen Fertilizing Level on Productivity of Pasture Plants and Improvement of Soil Fertility in Mixed Grassland (혼파초지에서 가축분뇨의 종류와 시용수준이 목초의 생산성 및 지력증진에 미치는 영향)

  • 육완방;최기춘
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.21 no.4
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    • pp.203-210
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    • 2001
  • To establish the recycling system of animal manure(AM) for environmental preservation and improve the utilization of AM, this study was to investigate the effects of the types and nitrogen application rate of AM on herbage productivity, efficiency of nitrogen utilization, nutritive value and an increase of soil fertility and in mixed grassland. This sudy was arranged in split plot design. Main plots were the types of AM(Cattle feedlot manure, CFM; Pig manure fermented with sawdust, PMFS; cattle sluny, CS) and subplots were the application rate of animal manure, such as 100, 200 and 300kgNiha. I. DM yields of herbage were the highest with CS and decreased by application over ZOOkgNiha AM. 2. Crude protein(CP) ontent was the highest with CFM and followed by CS, and the lowest with PMFS, and increased as application rate of AM increased. 3. Nitrogen(N) yields of CS treatment was higher than that of CFM and CS. and increased significantly as application rate of AM increased(P<0.05). 4. The contents of NDF, ADF and TDN was hardly influenced by the types and application rate of AM. 5. Organic matter(0M) content in the soil was the highest with PMFS and followed by CFM and the lowest with CS. OM content increased significantly as application rate of AM increased(P<0.05). 6. Total nitrogen content of the soil was not affected by the type of AM, but increased significantly as application rate of AM increased(P<0.05). (Key words : Animal manure, Grassland, Cattle feedlot manure, Pig manure fermented with sawdust, Cattle slurry, Soil fertility)

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A literature Study on the Application of Sa-am Acupuncture for the Treatment of Hiccup (애역의 사암침법(舍巖鍼法) 활용(活用)에 대(對)한 문헌고찰(文獻考察))

  • Chae, Choong-Heon;Yim, Yun-Kyoung
    • The Journal of Korean Medicine
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    • v.28 no.3 s.71
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    • pp.232-243
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    • 2007
  • Objective : This study researched the application of Sa-am acupuncture for the treatment of hiccup. Methods : We investigated the literature for Sa-am acupuncture treatment and traditional acupuncture treatment for hiccup. Result & Conclusion : In traditional oriental medicine, hiccup is considered to be caused by uprising stomach gi, whereas, in Sa-am acupuncture, it is considered to be caused by weakness and impurity of lung gi. In Sa-am acupuncture, hiccup is divided into five classes; reverse hiccup (treated with large intestine tonification), wind hiccup (treated with liver tonification), fire hiccup (treated with heart tonification), damp hiccup (treated with spleen tonification) and cold hiccup (treated with kidney tonification). In traditional oriental medicine, hiccup is treated by way of lowering the uprising stomach gi, while, in Sa-am acupuncture, hiccup is treated by way of removing whichever of the original cause of hiccups (impurity of large intestine, damage to liver, dry heat of heart, impairment of spleen, exhaustion of kidney) caused the weakness and the impurity of lung gi. In Sa-am acupuncture, the therapeutic mode for all the five causes of hiccups is tonification mode.

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A study on needs to introduce AM radio broadcasting high-efficiency transmission system (AM 라디오방송 고효율송출방식의 도입 필요성)

  • Lee, SangWoon
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2019.06a
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    • pp.108-109
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    • 2019
  • AM 라디오방송은 통상 수십~수백 KW 급의 대출력으로 송신을 하여 타 지상파 방송 매체에 비해 많은 전력을 필요로 하며, 이는 방송사의 재정적 부담을 안겨주고 있다. 본 연구에서는 AM 라디오 방송의 전력은 낮추고 음질과 서비스 커버리지는 동일하게 유지할 수 있는 송출효율을 높여 방송하는 방법들에 대해 고찰하고 적용 가능성을 검토하였다. 연구 결과 국내 AM 방송에 고효율방식의 송출이 기술적으로 가능하며, 이런 방식을 적용할 경우 송출 전력을 30% 이상 절감할 수 있을 것으로 예측되었으나, 현행 AM 라디오 방송에 관한 국내 기술기준으로는 적용이 불가하여 이의 개정이 전제되어야 함을 알 수 있었다. AM 라디오방송에 고효율송출방식을 적용할 경우 송출전력을 대폭 낮추어 방송사의 송출 전력요금 부담을 경감하고 유사 시 국민들을 위한 재난경보매체로서 활용이 가능할 것으로 기대된다.

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Inhibitive Effects of Baik-Kimchi Against Amaranth Toxicity in Rats (백김치의 Amaranth투여 흰쥐에 대한 독성억제효과)

  • ;Suzuki T.
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.6
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    • pp.1246-1252
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    • 2001
  • A feeding experiment was conducted on rats to investigate the inhibitive effects of baik-kimchi against the toxicity of Amaranth (Am, Food Red No.2) on growth, fecal weights and bulk, and the digestibility of protein and lipid. The body weight of the Am diet group (5% Amaranth) remained at the lowest level of all diet groups, because of diarrhea symptoms throughout the feeding period, 229.8 g of total body weight or 79.4% of the basal diet group (289.4 g). However, in the baik-kimchi diet group (10% baik-kimchi powder+5% Amaranth) no diarrhea symptoms were evident and total body weight remained at a similar level (280.3 g) to the basal diet group. It therefore appears that baik-kimchi offers an inhibitive effect against the toxicity of Am. In the baik-kimchi diet group, the total fecal weight (173.99 g/3 weeks) was 15 times that of the basal diet group (11.13 g/3 weeks) suggesting that baik-kimchi has the effect of increasing fecal bulk. The large intestine and the cecum of the baik-kimchi diet group were significantly (p<0.05) heavier than those of the Am diet group. The digestibility of protein (50.26%) and lipid (58.37%) in the Am diet group was very low in comparison with these in the baik-kimchi diet group (87.30% and 92.12%, respectively). This result indicates that the low digestibility of these nutrients in the Am diet group was directly responsible for the decrease of weight. Consequently, it is demonstrated that baik-kimchi can inhibit the effects of the toxicity of Am in rats.

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