백김치의 Amaranth투여 흰쥐에 대한 독성억제효과

Inhibitive Effects of Baik-Kimchi Against Amaranth Toxicity in Rats

  • 문수경 (경상대학교 해양생물이용학부/해양산업연구소) ;
  • ;
  • 정보영 (경상대학교 해양생물이용학부/해양산업연구소) ;
  • 류홍수 (부경대학교 식품생명공학부)
  • ;
  • Suzuki T. ;
  • ;
  • 발행 : 2001.12.01

초록

백김치의 생체내 Am독성억제효과를 확인하기 위하여 Am 식이에 10% 백김치(동결 건조분말) 첨가사료로 사육한 흰쥐 의 성장회복능을 실험한 결과를 요약하면 다음과 같다. Am 식이군의 섭취량이 양적으로 다른 군에 비해 적었으며, 기본 식이군 생배추식이군, 백김치식이군은 거의 같은 섭취량을 보였다. 기본식이군의 체중이 사육종료일에 289.4 g에 달하는데 비해 Am식이군은 229.8 g으로 기본식이군의 79.4%에 불과해 체중증가 현상이 크게 저조하였다. 그러나 백김치를 첨가한 식이군의 경우는 설사증상이 없어지고 체중도 기본 식이군의 경우와 비슷한 수준까지 회복상태를 보여 백김치의 Am에 대한 독성억제효과를 나타내었다. 변의 총배설량은 백김치식이군(1737.99 g/3 weeks)이 기본식이군의 약 15배, 생배추식이군의 약 1.6배로 백김치가 변부피를 증가시키는 데 가장 효과적인 것으로 확인되었다. 대장과 맹장의 무게는 생배추 및 백김치식이군에서 유의적 (P<0.05)인 증가를 나타내었다. 또한 신장의 무게는 Am식이군에서 유의적인 감소를 나타내어 Am의 독성이 신장과 깊은 상관성이 있음을 시사하고 있었다. Am식이군의 단백질(50.26%) 및 지질소화율 (58.37%)이 백김치식이군의 단백질(77.30%)및 지질소화율 (92.12%)에 비하여 매우 낮았는데, 이것은 이들 영양소의 낮은 소화율이 횐쥐의 체중저하에 직접적인 영향을 미친 것으로 생각되었다. 백김치의 수용성 및 불용성식이섬유는 소화관을 통과한 형태 변화가 뚜렷하게 관찰되었다. 변의 배설 형태는 백김치식이군의 변이 가장 부피가 크고 일정한 크기를 보였다.

A feeding experiment was conducted on rats to investigate the inhibitive effects of baik-kimchi against the toxicity of Amaranth (Am, Food Red No.2) on growth, fecal weights and bulk, and the digestibility of protein and lipid. The body weight of the Am diet group (5% Amaranth) remained at the lowest level of all diet groups, because of diarrhea symptoms throughout the feeding period, 229.8 g of total body weight or 79.4% of the basal diet group (289.4 g). However, in the baik-kimchi diet group (10% baik-kimchi powder+5% Amaranth) no diarrhea symptoms were evident and total body weight remained at a similar level (280.3 g) to the basal diet group. It therefore appears that baik-kimchi offers an inhibitive effect against the toxicity of Am. In the baik-kimchi diet group, the total fecal weight (173.99 g/3 weeks) was 15 times that of the basal diet group (11.13 g/3 weeks) suggesting that baik-kimchi has the effect of increasing fecal bulk. The large intestine and the cecum of the baik-kimchi diet group were significantly (p<0.05) heavier than those of the Am diet group. The digestibility of protein (50.26%) and lipid (58.37%) in the Am diet group was very low in comparison with these in the baik-kimchi diet group (87.30% and 92.12%, respectively). This result indicates that the low digestibility of these nutrients in the Am diet group was directly responsible for the decrease of weight. Consequently, it is demonstrated that baik-kimchi can inhibit the effects of the toxicity of Am in rats.

키워드

참고문헌

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