• The Korean Journal of Physiology and Pharmacology
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• v.2 no.4
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• pp.403-409
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• 1998

• Molecules and Cells
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• v.37 no.12
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• pp.851-856
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• 2014

ATAD2, a remarkably conserved, yet poorly characterized factor is found upregulated and associated with poor prognosis in a variety of independent cancers in human. Studies conducted on the yeast Saccharomyces cerevisiae ATAD2 homologue, Yta7, are now indicating that the members of this family may primarily be regulators of chromatin dynamics and that their action on gene expression could only be one facet of their general activity. In this review, we present an overview of the literature on Yta7 and discuss the possibility of translating these findings into other organisms to further define the involvement of ATAD2 and other members of its family in regulating chromatin structure and function both in normal and pathological situations.

• Journal of Korean Neurosurgical Society
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• v.63 no.6
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• pp.777-783
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• 2020

Objective : To compare the accuracy and breach rates of freehand (FH) versus navigated (NV) pedicle screws in the thoracic and lumbar spine in patients with metastatic spinal tumors. Methods : A retrospective review of adult patients who underwent pedicle screw fixation in the thoracic or lumbar spine for metastatic spinal tumors between 2012 and 2018 was conducted. Breaches were assessed based on the Gertzbein and Robbins classification and only screws placed >4 mm outside of the pedicle wall (lateral or medial) were considered breached. Results : A total of 62 patients received 547 pedicle screws (average 8 per patient) - 34 patients received 298 pedicle screws in the FH group and 28 patients received 249 screws in the NV group. There were 40/547 breaches, corresponding to a breach and accuracy rate of 7.3% and 92.7%, respectively. The breach rate was 9.7% in the FH group and 4.4% in the NV group (chi-squared test, p=0.017); this corresponded to an accuracy rate of 90.3% and 95.6%, respectively. Only one patient from the overall cohort (in the FH group) required revision surgery due to a medial breach abutting the spinal cord (1.6% of all patients; 2.9% of FH patients); no patient suffered organ, vessel, or neurological injury from screw breaches. Conclusion : Navigated pedicle screw placement in patients with metastatic spinal tumors has a significantly higher radiographic accuracy compared to the FH technique. However, the revision surgery was low and no patient suffered from clinically-relevant breach. Navigation also offers the advantage of real-time localization of spinal tumors and aids in targeting and resection of these lesions.

• Journal of Gastric Cancer
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• v.20 no.4
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• pp.385-394
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• 2020

Purpose: Patients with gastric cancer who receive neoadjuvant therapy are staged before treatment (cStage) and after treatment (ypStage). We aimed to compare the prognostic reliability of cStage and ypStage, alone and in combination. Materials and Methods: Data for all patients who received neoadjuvant therapy followed by surgery for gastric adenocarcinoma from 2004 to 2015 were extracted from the National Cancer Database. Kaplan-Meier (KM)curves were used to model overall survival based on cStage alone, ypStage alone, cStage stratified by ypStage, and ypStage stratified by cStage. P-values were generated to summarize the differences in KM curves. The discriminatory power of survival prediction was examined using Harrell's C-statistics. Results: We included 8,977 patients in the analysis. As expected, increasing cStage and ypStage were associated with worse survival. The discriminatory prognostic power provided by cStage was poor (C-statistic 0.548), while that provided by ypStage was moderate (C-statistic 0.634). Within each cStage, the addition of ypStage information significantly altered the prognosis (P<0.0001 within cStages I-IV). However, for each ypStage, the addition of cStage information generally did not alter the prognosis (P=0.2874, 0.027, 0.061, 0.049, and 0.007 within ypStages 0-IV, respectively). The discriminatory prognostic power provided by the combination of cStage and ypStage was similar to that of ypStage alone (C-statistic 0.636 vs. 0.634). Conclusions: The cStage is unreliable for prognosis, and ypStage is moderately reliable. Combining cStage and ypStage does not improve the discriminatory prognostic power provided by ypStage alone. A ypStage-based prognosis is minimally affected by the initial cStage.

• Annual Conference on Human and Language Technology
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• 2021.10a
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• pp.410-413
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• 2021

본 논문에서는 분류 모델의 주류로 사용되고 있는 Encoder 기반 사전학습 모델(BERT, ALBERT, ELECTRA)의 내부 Encoder Layer가 하부 Layer에서는 Syntactic한 분석을 진행하고 상부 Layer로 갈수록 Semantic 한 분석을 진행하는 점, Layer가 구성됨에 따라 Semantic 정보가 Syntactic 정보를 개선해 나간다 점에 기반한 기존 연구 결과를 바탕으로 Encoder Layer를 구성함에 따라 어떻게 성능이 변화하는지 측정한다. 그리고 의도 분류를 위한 학습 데이터 셋도 분류하고자 하는 성격에 따라 Syntactic한 구성과 Semantic한 구성을 보인다는 점에 착안하여 ALBERT 및 ELECTRA를 이용한 의도 분류 모델을 구축하고 각 데이터 셋에 맞는 최적의 Encoder Layer 구성을 가지는 모델을 비교한 결과, 두 데이터 셋 간에 다른 Layer 구성을 보이는 점과 기존 모델보다 성능이 향상됨을 확인하였다.

• Proceedings of the KIPE Conference
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• 1998.10a
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• pp.598-602
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• 1998

This paper refers to fundamental investigations and simulations of conducted electromagnetic inference emissions produced by power electronic devices in a frequency range from 2 to 10 kHz. The emissions of different industrial power converters were measured and compared. The influence of different working conditions over the altitude of the EMI are represented. Simulations of the power converter system including the line impedance stabilisation network certify the measurements.

• Korean Architects
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• v.5 no.1 s.17
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• pp.59-62
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• 1970

• 월간산업보건
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• s.81
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• pp.41-43
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• 1995

• 대한치과보철학회:학술대회논문집
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• 1999.11a
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• pp.105-105
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• 1999

• Therapeutic Science for Rehabilitation
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• v.4 no.2
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• pp.63-71
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• 2015

Objective : The purpose of this study was to investigate the effects of vibratory stimulation applied to the left forearm on unilateral neglect in patients with stroke. Methods : The subjects were 11 unilateral neglect patients with stroke. They were divided into 2 groups; 6 experimental subjects and 5 control subjects. Both groups received standardized rehabilitation program and occupational therapy for the intervention of unilateral neglect in a day. In random order, line bisection test (LBT), Albert test, and star cancellation test (SCT) were conducted at baseline, the next day. During the process of all assessments of the next day, vibration stimulation was provided for the 6 subjects in the experimental group (EG), while the 5 subjects in CG carried out all assessments without vibration stimulation. Result : No significant differences were found between groups on any demographic variable or baseline assessments scores. In the next day, there was significant improvement in the EG for the LBT(p<0.05), Albert's test(p<0.05), and SCT(p<0.05). However, there was no significant improvement in the CG for the LBT(p<0.05), Albert's test(p<0.05), and SCT(p<0.05). Conclusion : These result indicate that vibratory stimulation has a positive effect on the unilateral neglect, and may be considered as alternative choice in clinical occupational therapy for reducing unilateral neglect.