• 제목/요약/키워드: AGEs

검색결과 5,519건 처리시간 0.04초

최근 5년간 연령에 따른 근시 유병률 진행에 관한 연구 : 2008년에서 2012년 중심으로 (A Study on the Progression and Prevalence of Myopia according to Age for the Last Five Years : from 2008 to 2012)

  • 이완석;예기훈;신범주
    • 한국안광학회지
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    • 제19권1호
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    • pp.121-133
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    • 2014
  • 목적: 본 연구는 최근 5년간 연령에 따른 근시 유병률 진행을 비교 분석하였다. 방법: 보건복지부 산하 질병관리 본부에서 시행한 2008에서 2012년까지의 국민건강영양조사 자료를 통해 근시 유병률 진행을 비교 분석하였다. 결과: 최근 5년간 자료를 통해 근시를 분류하였고, 연령별 분석결과 약도근시 중 5-11세는 25.5%, 12-18세는 25.1%, 19-29세는 27.3%, 30-39세는 30.7%, 40-49세는 29.6%, 50-59세는 19.2%, 60-69세는 11.8%, 그리고 70세 이상에서는 20.2%의 근시유병률이 각각 나타났다. 중도근시 중 5-11세는 21.7%, 12-18세는 43.6%, 19-29세는 36.2%, 30-39세는 30.0%, 40-49세는 20.4%, 50-59세는 9.9%, 60-69세는 5.2%, 그리고 70세 이상에서는 7.6%의 근시 유병률이 각각 나타났다. 고도근시 중 5-11세는 2.1%, 12-18세는 11.7%, 19-29세는 11.5%, 30-39세는 6.9%, 40-49세는 5.6%, 50-59세는 1.9%, 60-69세는 1.5%, 그리고 70세 이상에서는 1.0%의 근시 유병률이 각각 나타났다. 결론: 근시 유병률 진행 증가에 대한 중요성을 인식하여 국민의 안보건복지와 시력저하 방지를 위한 제도적 장치와 사회적 관심이 더욱 필요할 것을 판단된다.

제2형 당뇨병 환자에서 최종당화산물과 heme oxygenase-1의 상관성 (Correlation of advanced glycation end products and heme oxygenase-1 in Korean diabetic patients)

  • 최하늘;구다혜;임정은
    • Journal of Nutrition and Health
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    • 제55권3호
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    • pp.348-358
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    • 2022
  • 본 연구는 한국에서 최초로 시행되는 연구로서, 성인 제2형 당뇨환자에서 혈청 AGEs의 농도에 따라 두 군으로 나눈 뒤 신체계측 및 체조성, 영양소 섭취량, 생화학적 지표를 비교 분석한 연구이다. Low AGEs group과 High AGEs group의 평균 AGEs는 각각 0.4 ± 0.2, 3.4 ± 1.7 ng/mL로 나타났다. 항산화 효소인 HO-1은 High AGEs group이 Low AGEs group에 비해 유의적으로 높게 나타났다. 또한, 전체 연구참여자를 대상으로 연령과 성별을 보정한 후 상관관계를 분석한 결과, 혈청 HO-1 농도와 혈청 AGEs 농도 및 소변 8-OHdG 농도는 양의 상관관계를 가지는 것으로 나타났다. 본 연구를 통해 혈청 HO-1은 당뇨환자 특이적 지표인 AGEs와 더불어 DNA 손상 지표에도 예민하게 반응하는 것을 확인하였으며, 추후 한국 당뇨환자의 산화적 스트레스와 합병증 연구의 근거자료로 널리 사용될 수 있을 것으로 사료된다.

서양 남성 속옷의 변천에 관한 고찰-고대에서 근세까지 (Changes of Western Men's Underclothes)

  • 김주애
    • 한국의류학회지
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    • 제24권3호
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    • pp.353-360
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    • 2000
  • The purpose of study examined the changes of the man's underclothes from the ancient ages to the early modern ages. The method of study researched literatures and possessions of the museum. In ancient ages, a suit of clothes had the functions of both underclothes and outer garments. In middle ages, underclothes were not exposed and the importance was not recognized while they were worn to show the sense of sin and humility or to punish criminals. In early modern ages, the importance of underclothes recognized as they were exposed. In Renaissance period, the fashion of the day influenced much on the underclothes. In Baroque ages, the functions of underclothes were different according to sexes and men wore underclothes to show their social status. As the outer garments were shortned, shirt wwere also conspicuously exposed. In Rococo ages, drawers were tightened due to the influence of outer garments, men exposed their shirts to show the social status and underclohtes were usually worn to express sexual attraction. Men's underclothes had the functions of class distinction from the ancient ages to the modern ages, except the middle ages and underclothes had the additional functions such as supporting body-shape and sex attraction. The fashion of the day influenced on the changes of the shapes of the shapes of men's underclothes and the changes of outer garments were reflected on underclothes.

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로코코시대 헤어스타일의 조형적 특성을 응용한 업스타일에 관한 연구 (A Study on the Upstyle Applied Formative Characteristics of Hairstyle in Rococo Ages)

  • 신부섭
    • 한국패션뷰티학회지
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    • 제4권2호
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    • pp.42-49
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    • 2006
  • This study aims to revive modernized upstyle technique by analyzing the formative characteristics of hairstyle in Rococo ages. As a methodology, book-form literatures, periodicals, theses, and photographic materials including portraits related to Rococo ages, which had been studied from the time when Louis XIV died, to the advent of French Revolution in 1789, reaching a period of seventy-four years, were reviewed. Those materials for hairstyle revealed in modern fashion included related literatures and theses and photographs involving designers' works in fashion magazines, photographs of hairstylists' works, and movies with background of Rococo ages. Based on such materials, the formative characteristics of hairstyle in Rococo ages were studied for modernized upstyle. First, the formative characteristics of hairstyle in Rococo ages were divided and analyzed in Fontnage style, in Pompadour style Marie Antoinette style. Second, this study researched those examples wherein the characteristics of Rococo's hairstyle were expressed in modernized style, and manufactured modern upstyle works based on the research. Rococo ages featured various fashion trends and created sensitive and magnificent style with romantic theme in art field. Also, since the hairstyle in Rococo ages featured various styles that were magniloquent and magnificent, it is revived in today's hair shows and fashion shows in the same way or altered way. It is expected that this study will help understand the formative characteristics of hairstyle in Rococo ages and shed light on study on modern hairstyle in more various perspectives.

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성격 특성에 관한 체질판별 문진항목의 통계적 분석 (A Statstical Analysis of the Question Categories concerning 'Sasang Constitutional Characteristics of Mind')

  • 김흥기;김종열
    • 사상체질의학회지
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    • 제15권3호
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    • pp.124-138
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    • 2003
  • Objectives : To evaluate the properness and effectiveness of the question categories concerning 'sasang constitutional characteristics of mind', used in Iksan Wonkwang Oriental Medicine. Methods : We statistically analyzed data from those 1335 patients focussing on 'relative discrimination ability' to sasang constructions and 'response ratio'. Patients included in this research are only those who had been well treated in Iksan Wonkwang Oriental Medicine during the Period of three years from 2000 to 2002. The data are obtained through the electronic chart developed by Kim Jong-Yeal, and analyzed using the statistical Package SPSS. Results: In total characteristics of mind, the question category of 'timid' has high discriminating power and effectiveness to Soeum type, more in women than men, and especially with an age of 21 or more; The category of 'hasty-tempered' to Soyang type in women with all ages and men with ages 21-40; The category of 'broad-minded' to Taeum type with ages 41 or more; The category of 'timid and broad-minded' to Soyang type, and especially high to women with ages 41 or more. Question categories concerning response type in anger were estimated to have different response patterns to sasang constructions only for ages 21 or more by $X^2$2 test. The question category of 'bear and last long' has high discriminating power and effectiveness to Soeum type, more in men than women, and increasingly to ages; The category of 'impatient and disarmed quickly' to Soyang type in both women and men, especially with ages 21 or more; The category of 'impatient' to Soyang type women or with ages 21 or more. Other categories have low discriminating power or low effectiveness. Concernig expression type of one's thought, the question category of 'straightly' has high discriminating power and effectiveness to Soyang type, more in wemen than men, and especially to ages 21 or more; The category of 'tender' to Soeum type, in women or with ages 40 or less; The category of 'indirectly' to Taeum type in men or with ages 41 or more; The category of 'straightly and stuborn' to Soyang type with ages 41 or more; The category of 'indirectly and tender' to Soeum with with ages 20 or less; The category of 'not express and tender' to Soeum type with ages 41 or more; Conclusions : Question categories concerning total characteristics of mind, response type in anger and expression type of one's thought, are partially discriminating and effective to specific constitution according to sex and ages, and some categories are more discriminating and effective when they are composited. But generally, the discriminating power of Taeum constitution group and group with ages 20 or less was too low, so it is necessary to develope question categories for those groups.

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자각적 검사를 이용한 조절력에 관한 임상적 연구 (Clinical Study on Accommodation Using Subjective Test)

  • 정미분;이기석;김태훈;성아영
    • 한국안광학회지
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    • 제11권2호
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    • pp.137-141
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    • 2006
  • 현 호남지역에 거주하는 10대에서 60대의 조절력을 측정하고, 이미 알려진 나이에 따른 조절력을 비교해 보았다. Push-up method을 사용하여 조절력을 측정한 결과, 각각 연령대의 평균조절력을 보면 10대 9.88D, 20대 8.65D, 30대 6.92D, 40대 5.05D, 50대 4.29D, 60대 4.63D의 결과를 얻을 수 있었다. 조절력은 나이가 많아짐에 띠라 감소함을 알 수 있었지만 이 조사에서는 50, 60대에서 상당히 높은 조절력을 보였다. 이는 앞으로 타 지역의 조절력 조사와 근용 가입도 및 조절력 검사에 참고해야 할 것으로 사료된다.

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선(先)캠브리아기(紀) 분천(汾川) 및 홍제사화강암류(홍제사화강암류)의 흑운모(黑雲母)에 대(對)한 K-Ar 연대측정(年代測定) (K-Ar Ages on Biotites of the Proterozoic Buncheon and Hongjesa Granitic Rocks in the northeastern Part of the Sobaegsan Massif)

  • 홍영국;최태윤
    • 자원환경지질
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    • 제19권2호
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    • pp.147-151
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    • 1986
  • K-Ar ages on biotites have been determined from the Proterozoic Buncheon and Hongjesa granitic rocks in comparison with the Rb-Sr whole-rock ages to investigate the ages of metamorphic events. The Rb-Sr whole-rock ages determinations on the Buncheon and Hongjesa granitoid rocks were previously reported as 2,100Ma and 1,700Ma, respectively. K-Ar ages on biotites separated from the studied rock have revealed three different age groups such as 1) 1,200~1,300Ma, 2) 600~700Ma and 3) 300~400Ma. The Rb-Sr whole-rock ages for the granitic rocks represent the time of emplacement, whereas the K-Ar ages on biotites generally indicate the time of metamorphism or alteration. The large discordance in the two age systems may not be explained as indicating the cooling period of the granitic batholiths. The K-Ar ages on biotites from the granitoid rocks might not be simply interpreted as the age of the last phase of metamorphism, since the granitic rocks had been undergone multistages of amphibolite facies-metamorphism in the Precambrian period. During the multistages of intermediate grade metamorphism, $^{40}Ar$-loss could be inevitably taken place as the metamorphic temperatures went up above the blocking temperature of biotite ($300{\pm}50^{\circ}C$). The results of the K-Ar dating on biotites from this study are probably minimum ages or hydrothermal alteration ages.

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포제한약재의 최종당화산물 생성 억제 활성 및 항산화 효과 (Inhibitory Activity of Advanced Glycation Endproducts (AGEs) Formation and Antioxidant Activity of Processed Korean Medicines)

  • 이아름;권오준;최준영;노성수
    • 대한본초학회지
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    • 제32권3호
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    • pp.63-69
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    • 2017
  • Objectives : Advanced glycation end product (AGEs) is combine formation of glucose and protein. AGEs and reactive oxygen species are potential therapeutic targets for the various disease such as diabetic complications, renal injury, skin damage. The aim of this study was investigated the AGEs inhibitory activity and antioxidant activity of water extracts from 40 Korean medicines and 5 heating-processed Korean medicines. Methods: AGEs formation inhibitory activities of Korean medicines measured using bovine serum albumin (BSA), glucose, and fructose. Then, five effective Korean medicines were selected and heated with 30% ethanol. The AGEs inhibitory activities of heated Korean medicine were measured compared with not-heated Korean medicines. The antioxidant activities were evaluated through radical scavenging assays using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radicals. Furthermore, we examined total phenol and flavonoids contents. Results: Scutellariae Radix, Corni Fructus, Persimmon Fruit, Paeoniae Radix, Mori Folium respectively reduced AGEs production. Morever, heating-processed Scutellariae Radix has AGEs inhibitory activities better than not-processed Scutellariae Radix. Heating- processed Scutellariae Radix scavenged DPPH and ABTS effectively and $IC_{50}$ of DPPH and ABTS radical scavenging activity of Heat processed Scutellariae Radix were $15.47{\pm}0.26{\mu}g/m{\ell}$ and $12.07{\pm}1.23{\mu}g/m{\ell}$. It caused heat processing methods of Scutellariae Radix up regulated total phenol and flavonoids contents ($26.68{\pm}0.01$ to $46.15{\pm}0.10$, $20.30{\pm}0.38$ to $64.20{\pm}0.52$). Conclusion: It has AGEs inhibitory activities that 20 kind of medicinal plants of 40 medicinal plants. Especially, heat processed Scutellariae Radix has excellent AGEs inhibitory activities and antioxidant effect.

수도원 수학과 중세 미술

  • 계영희
    • 한국수학사학회지
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    • 제16권3호
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    • pp.77-88
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    • 2003
  • In this paper, we consider relationship of the monastic mathematics and the arts of the middle ages. Because mathematics and arts are effects of the spirit of the ages. Here, we concern with the Rome and the religion of Christ. Next, we think of the bible and Christian doctrine and then compare with Christian arts and arts of the customs of the middle ages. The middle ages is the period of women's inequality according to the feudal system. So we investigate the correlation of the christianity, arts of the middle ages, women's inequality and monastic mathematics which is worthless in mathematics history.

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떫은감과 포제 떫은감의 최종당화산물 생성 억제를 통한 피부 탄력 개선 효과 (Skin elasticity improvement effect of Young persimmon and Heated young persimmon by decreased Advanced glycation end products(AGEs))

  • 김수현;이아름;김수지;김경조;권오준;최준영;구진숙;노성수
    • 대한본초학회지
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    • 제32권4호
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    • pp.17-24
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    • 2017
  • Objectives : Advanced glycation end products (AGEs) is bind formation of glucose and protein. Acceleration of AGE formation during hyperglycemia is associated with the pathogenesis of diabetic complications and causes kidney and skin damage. The aim of this study was investigated the AGEs inhibitory activity and antioxidant activity of water extracts from young persimmon (YP) and heated young persimmon (HYP). Methods : Paeoniae Radix Alba (YP) is prepared by heating with 30% ethanol. AGEs formation inhibitory activities of YP and HYP measured using bovine serum albumin. To evaluate the protective effects of YP and HYP in diabetic rats induced with streptozotocin (STZ) and methyl glyoxal (MGO), SD rats were distributed into four groups; normal mice (Nor), AGEs-induced rats (Con), AGEs-induced rats treated with 100 mg/kg YP (YP), AGEs-induced rats treated with 100 mg/kg heated YP (HYP) for 3weeks. Heated young persimmon respectively decrease AGEs construction. Results : YP and HYP administration inhibited the biomarkers of AGEs in serum, kidney and skin tissues. AGE-induced rats revealed that the significant decreased collagen however, heat processing methods of young persimmon up regulated inhibits AGEs-induced collagen decrease. The expressions of AGEs were decreased in YP and HYP treated group compared with the control group in tissues. It specifies that HYP has potential to serve as a positive regulator of via AGEs path way. Conclusion : It has proposed that may have an improvement effect on diabetic complications, heated young persimmon has AGEs inhibitory excellent activities and antioxidant effect.