• 생명과학회지
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• 제19권10호
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• pp.1374-1381
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• 2009

본 연구는 남성 음주자의 나이대별 생리학적 변수들에 어떠한 차이가 있는지를 연구하였다. 30대 남성들은 waist-hip ratio, 좌 우 심장-발목 혈관지수, 좌 우 발목-상완지수, 아밀라제, hs-CRP, CPK가 가장 낮았고 체중, IL-6, 좌 우 안와혈압, 혈색소, 적혈구수, 적혈구 분포도, ALT, 총 콜레스테롤, 중성지방, 페르틴 농도는 높게 나타났다. hs-CRP, CPK는 40대 음주남성에서 높았지만 페리틴 농도는 반대였다. 50대 음주남성에서는 WHR이 높았으며 이완기 혈압, 좌 우 안와혈압, 호산구와 아밀라제 농도는 높게 나타냈다. 60대 음주남성에서는 좌 우 심장-발목 혈관지수, 평균 혈색소 농도, $\gamma$-GTP, RF, AFP, PSA의 농도는 높았으며, 체중, 이완기 혈압, 좌 우 안와혈압, 혈색소, 혈소판, 백혈구, 적혈구 분포지수, 호산구, 단구, 아밀라제 중성지방, CPK 농도 변화에서는 높게 나타났다. 이러한 결과를 볼 때 음주는 남성들에 있어 나이대별로 다양한 생리학적 변화를 유도 할 것으로 사료된다. 향후 음주가 성별, 즉 남녀 간에 미치는 생리학적 영향의 차이에 대한 연구 역시 더 필요할 것으로 생각된다.

• The Journal of Korean Physical Therapy
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• 제34권1호
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• pp.18-25
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• 2022

Purpose: The purpose of this study was to identify changes in physical activity, sleep quality, and quality of life (QOL) during COVID-19 in adults by age group. Methods: An online survey was conducted on a total of 160 participants who were divided into three groups by age; young adults, middle-aged adults, and old adults. The participants responded to the self-reported assessment of the impact of social distancing during COVID-19, International Physical Activity Questionnaire (IPAQ), Pittsburgh Sleep Quality Index (PSQI), and Short Form-36 Health Survey (SF36). Descriptive statistics, analysis of variance, and Pearson's correlation were used for data analysis. Results: There were significant differences between the three age groups in physical activity (p<0.05) and PSQI (p<0.01) and a post hoc analysis showed that the young adults' group had significantly higher physical activity than the old adults' group, while the old adults' group had significantly lower scores of PSQI (better sleep quality) than the others. The young adults' group showed a significant negative correlation between the stress from social distancing and QOL (r=-0.27, p<0.05) and between PSQI and QOL (r=-0.48, p<0.05). For the middle-aged adults' group, there was a significant negative correlation between PSQI and QOL (r=-0.53, p<0.05). The old adults' group showed a significant negative correlation between the stress from social distancing and physical activity (r=-0.35, p<0.05) and PSQI (r=-0.50, p<0.05), while there was a significant positive correlation between physical activity and PSQI (r=0.30, p<0.05) and QOL (r=0.30, p<0.05). Conclusion: The results of this study could be used as basic data for the promotion of physical and mental health in the post-COVID-19 era.

• 보건행정학회지
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• 제8권2호
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• pp.191-215
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• 1998

This descriptive correlational study was done to identify ICU nurses' intention to use restraints and related factors using Ajzen and Madden(1986)'s Theory of Planned Behavior. Self-reported questionnaires were used to measure intention and related factors. The subjects of this study were 287 ICU nurses in 21 general hospitals with at least 200 beds at Taegu, Pusan and Kyungbuk area in Korea. The results of this study were : 1. There were significant differences in intention according to age and marnital status, attitude according to educastion(with indirect measure), subjective norm according to career in ICU(with both measures), perceived behavioral control according to age and career in ICU(with direct measure), and knowledge according to education and position. 2. There were significant correlations among intention and all factors. Intention was correlated with attitude(r=.2119), subjective norm(r=.1112), and perceived behavioral control(r=.3448) with direct measure. Attitude was correlated with subjective norm(r=.2530), perceived behavioral control(r=.3005), and knowledge(r=.1388) with direct measure. Subjective norm was correlated with perceived behavioral control(r=.1321) with direct measure. Intention was correlated with attitude(r=.1496) and perceived behavioral control(r=.2922) with indirect measure. Attitude was correlated with subjectivenorm(r=.2829) and knowledge(r=-.1390) with indirect measure. Also, subjective norm was correlated with perceived behavioral control(r=.2363) with indirect measure. 3. ICU nurses' intention to use restraints was explained 16.7% by perceived behavioral control, attitude with direct measure, control belief, and age. By this study, it was foundr that ICU nurses reported high level of intention to use restraints. The most important predictor of intention to use restraints was perceived behavioral control toward using restrains, which reflected the easiness and difficulty in the use of restraints.

• Asian-Australasian Journal of Animal Sciences
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• 제2권2호
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• pp.99-102
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• 1989

The level of serum alkaline phosphatase activity was determined in 7 Japanese Black steers at different ages. The isoenzyme activity of non-bone origin was estimated using a heat-inactivation technique. The activity of serum alkaline phosphatase (SALP, K-A unit) decreased as age (AGE, mo.) increased: SALP = 14.15 - 0.17 (${\pm}\;0.03$) AGE, r = -0.81, P<0.01, $S.E.\;{\pm}\;0.28$. The variation of the activity was greater in younger age than the older. The temperature of $58^{\circ}C$ for the treatment of heat inactivation of bovine serum appeared to be suitable. The percentage of heat inactivated enzyme activity negatively correlated with age and positively with the level of serum alkaline phosphatase activity. The activity of SALP of non-bone origin was inferred to stay at about constant level irrespective of age and that of bone origin decreased with age.

• Asian-Australasian Journal of Animal Sciences
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• 제9권4호
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• pp.455-459
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• 1996

The genetic parameters for various economic traits were estimated in a White Leghorn population selected for part period egg production over 16 generations. In early part of selection, egg number had moderate to high heritability (0.26 to 0.51) while age at sexual maturity, egg weight and body weight at 20 and 40 weeks of age had high heritability (0.54 to 0.83). The sire component heritability for all the traits except 20 week body weight declined in later periods of selection. Sex linked gene effects for egg number and age at sexual maturity were more important in early periods of selection in comparison to the later periods, while maternal effects remained important for 20 week body weight in all the periods. Egg number was negatively correlated with egg weight ($r_{G(S)}=-0.36$), age at sexual maturity ($r_{G(S)}=-0.84$) and 40 week body weight ($r_{G(S)}=-0.84$), while it was positively correlated with 20 week body weight ($r_{G(S)}=-0.34$) in base generation. The genetic association between egg number and 40 week body weight changed not only in magnitude but also in direction in later periods. The genetic correlation of egg number with egg weight as well as with age at sexual maturity also decreased in magnitude in later periods of selection.

• Toxicological Research
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• 제11권2호
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• pp.261-266
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• 1995

Age-related change in the frequency of spontaneous sister chromatid exchange (SCE) and chromosornal aberrations were investigated in bone marrow cells of accelerated senescence-resistant mice (SAM R1) and senescence accelerated ones (SAM P1). And the effect of chronic treatment of ginseng extract (Panax ginseng C.A. Meyer) on these chromosomal abnormalities was tested in SAM P1. SCE frequency in the cells was progressively increased with age in both mice, but it was consistently higher in SAM P1 than in SAM R1 at all corresponding age. Chromosomal aberrations were, however, not significantly changed with age except that it was slightly increased in only aged SAM P1. Interestingly, the rate of these genetic instabilities in SAM P1 was remarkably retarded by long-term administration of ginseng water extract (0.05% in drinking water). These results suggest that frequency of spontaneous SCE in bone marrow cells increase in parallel with senescence of the mice, and SAM P1 is in the condition of being more exposed than SAM R1 to DNA damaging factors. These also indicate that long-term treatment of ginseng may reduce the genetic damage.

• Interdisciplinary Bio Central
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• 제3권3호
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• pp.11.1-11.5
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• 2011

The MRI (magnetic resonance imaging) volumetric analysis of the brain was performed in 59 healthy elderly Koreans (aged 62-76 years; 34 male, 25 female) to investigate whether the previously reported significant correlations between body height and brain volumes in the young aged Koreans (20's) still exist in the old aged Koreans (60's and 70's). Unlike previously reported significant correlations in the young aged Koreans, neither the correlation between whole brain volume and body height in male nor the correlation between cerebellar volume and body height in female show any significance in the old aged Koreans. The significant correlation between body height and whole brain volume was still observed when both male and female data were combined (r=0.27, P<0.05), but the correlation coef-ficient and the level of significance markedly decreased from those of previously reported Korean youth data (r=0.67, P<0.01). Simple linear regression analysis shows decrease of explanatory power of height (measured in $r^2$) from 44% in the youth group to 7% in the old age group on the variance of whole brain volume. Multiple linear regression analysis shows that age and sex, rather than height, are major explanatory variables for whole brain volume in the old aged Koreans. The loss of correlations in the aged group is suspected to be mainly due to age related brain volume changes.

• Clinical and Experimental Pediatrics
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• 제59권11호
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• pp.425-431
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• 2016

The waist-to-height ratio (WHtR), calculated by dividing the waist circumference (WC) by height, has recently gained attention as an anthropometric index for central adiposity. It is an easy-to-use and less age-dependent index to identify individuals with increased cardiometabolic risk. A WHtR cutoff of 0.5 can be used in different sex and ethnic groups and is generally accepted as a universal cutoff for central obesity in children (aged ${\geq}6$ years) and adults. However, the WHtR has not been validated in preschool children, and the routine use of WHtR in children under age 6 is not recommended. Prospective studies and meta-analysis in adults revealed that the WHtR is equivalent to or slightly better than WC and superior to body mass index (BMI) in predicting higher cardiometabolic risk. In children and adolescents, studies have shown that the WHtR is similar to both BMI and WC in identifying those at an increased cardiometabolic risk. Additional use of WHtR with BMI or WC may be helpful because WHtR considers both height and central obesity. WHtR may be preferred because of its simplicity and because it does not require sex- and age-dependent cutoffs; additionally, the simple message 'keep your WC to less than half your height' may be particularly useful. This review article summarizes recent publications on the usefulness of using WHtR especially when compared to BMI and WC as a screening tool for obesity and related cardiometabolic risks, and recommends the use of WHtR in clinical practice for obesity screening in children and adolescents.

• Journal of Oral Medicine and Pain
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• 제40권2호
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• pp.55-62
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• 2015

Purpose: The aims of this study were to evaluate the differences in subjective symptoms, clinical characteristics, distribution according to Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) subgroup, psychological profile of TMD patients, and to identify the prevalence and trend according to age. Methods: A total of 1,052 patients (261 men and 791 women; mean age, $34.40{\pm}15.73$ years) who visited the Orofacial Pain Clinic of the Department of Oral Medicine, Seoul National University Dental Hospital complaining of TMD symptoms of were evaluated. All patients were questioned for medical history, clinical symptoms and contributing factors. Clinical examination and patient grouping based on RDC/TMD was conducted. Radiographies were taken. The Korean version of RDC/TMD axis II and Symptom Checklist-90-Revision (SCL-90-R) were administered to evaluate pain-related disability level and psychological status of the patients. Results: Prevalence peaked in the 20-year-old age group. There were more women than men in all groups. The highest T-score among SCL-90-R dimensions was somatization in each group, except for teenagers who showed the highest T-score in interpersonal sensitivity. The 30-year-old age group showed the highest distribution of high disability based on the graded chronic pain scale. Age was positively associated with pain intensity (r=0.100), number of positive muscles on palpation (r=0.137) and negatively associated with maximum mouth opening (r=-0.168). Conclusions: Subjective symptoms and clinical characteristics of TMD patients show distinct tendencies according to different age groups. Treatment should be customized and personalized according to age for efficient symptom resolution and patient satisfaction.

• 한국어류학회지
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• 제26권3호
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• pp.194-201
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• 2014

태안 연안에서 이각망에 어획된 숭어 이석을 관찰하여 연령을 사정하고, 이석 윤문의 폭으로부터 체장을 역추정하여 성장을 추정하였다. 태안 연안 숭어는 외해에서 산란하여 유어기를 보낸 후 성어가 연안으로 들어온 것으로 보이며, 관찰한 숭어의 전장은 239~605 mm 범위였으며, 400~550 mm 크기의 개체가 주를 이루었다. 나이는 1~7세 범위였고 3~5세어가 가장 많았다. 전장(L, mm)은 이석의 장반경(R, ${\mu}m$)에 유의하게 일차 비례하였다(L=15.3+87.9 R). Frazer-Lee의 방법으로 추정한 각 연륜이 형성되었을 때의 전장은 1세어의 평균(${\pm}SD$)은 $316{\pm}40.6mm$로 초기 성장이 빨랐으며, 각 나이에서 그 범위가 넓어 개체에 따른 성장률 차이가 큰 것으로 보인다. 역추산한 전장은 Von Bertalanffy의 성장식 $L_t=542[1-{\exp}\{-0.493(t+0.769)\}]$로 유의하게 회귀되었다.