• The Journal of Korean Medicine
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• v.29 no.1
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• pp.1-6
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• 2008

Objective : To investigate the therapeutic effect of manual acupuncture at Siguan (four gates, bilateral LI4 and LR3) on suppression of gastrointestinal motility. Methods : A single blind, randomized, sham-acupuncture controlled, crossover study was conducted. Twenty healthy male subjects were admitted at hospital, and gastrointestinal motility suppression was induced by loperamide administration. Just after intake of 20 radio-markers, four gates or sham acupoint treatments were administered every 12 hours, 4 times over 48 hours. Gastrointestinal motility was evaluated by radiographic distribution of the radiomarkers at stomach or ileum, ascending, transverse, descending colon, sigmoid/rectum, and outside body at serial time points (0, 6, 12, 24, and 48 h). Results : Four gates acupuncture activated gastrointestinal movement as evidenced by significantly changed distributionof radio-makers at 6, 12, and 48 hours (P < 0.0001, P = 0.001, and P = 0.03, respectively) in Cochran-Mantel-Haenszel statistics. No serious adverse events occurred in either group. Conclusions : This study showed a scientific clinical relevance of four gates acupuncture to gastrointestinal disorders.

• Journal of Korea Water Resources Association
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• v.38 no.4 s.153
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• pp.301-311
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• 2005

The purpose of this study is to assess the quantitative effect of stream discharge due to land use changes. The upstream watershed of Pyeongtaek gauging station of Anseong-cheon ($592.6\;km^2$) was adopted. To accomplish the purpose, firstly, trace land use changes for the selected watershed which have some changes of land use by using Landsat images of 1986 and 1999 of the watershed and secondly, analyse the quantitative effect of stream discharge due to land use changes by applying GIS- based distributed hydrologic model KIMSTORM. The model was calibrated and verified at 2 locations (Pyeongtaek and Gongdo) by comparing observed with simulated discharge results for 7 storm events from 1998 to 2003. Model output was designed to provide information of land use impact on runoff components in the watershed and the sensitivity of impact level of each land use category on storm runoff. Land use impact was evaluated with the land use data sets for 1986 and 1999 for the same rainfall condition (160.5 mm). Area decrease of 4.8 percent of forest and 4.0 percent of paddy field during 13 years (1986 - 1999) within the watershed caused a 30.3 percent increase of peak runoff and a 9.3 percent increase of runoff volume.

• Journal of Acupuncture Research
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• v.29 no.5
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• pp.109-118
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• 2012

Objectives : The aim of this study was to evaluate the effectiveness and safety of acupuncture for chronic fatigue syndrome and idiopathic chronic fatigue. Methods : A randomized, controlled pilot trial was conducted. Twenty-four participants were randomized into one of the two groups: an acupuncture group(n=12) and wait-list group(n=12). The treatment group received 12 sessions of acupuncture over 4 weeks. Eight points($GV_{20}$; bilateral GB20, $BL_{11}$, $BL_{13}$, $BL_{15}$, $BL_{18}$, $BL_{20}$, and $BL_{23}$) were selected for needling. The control group did not receive acupuncture treatment during study period and follow-up were done in the $5^{th}$ and $9^{th}$ weeks after randomization in both groups. The primary outcome was fatigue severity scale(FSS) and the secondary outcomes included a short form of stress response inventory(SRI-short form), beck depression inventory(BDI), and insomnia severity index(ISI). Safety was assessed at every visit. Results : There were statistically significant differences in the between group values of FSS at $5^{th}$ weeks after randomization(p=0.0002), SRI-short form, BDI, and ISI at $5^{th}$, $9^{th}$ weeks after randomization(p<0.01). There were no adverse events. Conclusions : The results suggest that acupuncture is associated with benefits on the short-term outcomes in chronic fatigue syndrome and idiopathic chronic fatigue.

• Journal of Plant Biotechnology
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• v.34 no.4
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• pp.375-380
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• 2007

This study was conducted to develop herbicide-resistance domestic maize plants by introducing the CP4 5-enol-pyruvylshikimate-3-phosphate synthase (CP4 EPSPS) gene using Agrobacterium tumefaciens-mediated immature embryo transformation. Immature embryos of five genotypes (HW1, KL103, HW3, HW4, HW7) were co-cultivated with strains Agrobacterium tumefaciens (strain C58C1) containing the binary vector (pCAMBIA2300) carrying Ubiquitin promoter-CP4 EPSPS gene and Cauliflower mosaic virus 35S (CaMV35S) promoter-nptll gene conferring resistance to paromomycin as a selective agent. The presence and expression of CP4 EPSPS transgene were confirmed by PCR, RT-PCR and Northern blot analysis, respectively. Also, the resistance to glyphosate in the transgenic maize ($T_1$) was analyzed by shikimate accumulation assay. The frequency (%) of paromomycin-resistance callus was 0.37, 0.03, 2.20, 2.37, and 0.81% in pure lines HW1, KL103, HW3, HW4 and HW7, respectively. EPSP transgene sequences were amplified in putative transgenic plants that regenerated from paromomycin-resistance calli of two inbred lines (HW3, HW4). Of them, RT-PCR and Northern blot analyses revealed that the transgene was only expressed in two transgenic events (M266, M104) of HW4 inbred line, and a mild glyphosate resistance of transgenic event (M266) was confirmed by the lower shikimate accumulation in leaf segments. These results demonstrate that transgenic maize with herbicide-resistance traits in Korean genotype can be genetically obtained.

• Korean journal of food and cookery science
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• v.28 no.3
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• pp.327-335
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• 2012

This study was reviewed the changes in main ingredients, seasonings and cooking methods of Tangpyeongchae in Korean cook books and literatures published from the 1700s to the 1960s. The first published books about Tangpyeongchae were in Kosasibijib and Kyongdojabji, written in 1783 and the late 1700s, respectively. Tangpyeongchae, a representative traditional Korean dish that was royal cuisine offered at ritual events in the Chosun Dynasty, was called Cheongpochae in the royal court. It was a dish made by mixing cheongpomuk (mung bean gel), meat, dropwort, mung bean sprout, egg strips and laver. This dish has been seasoned with vinegar, soy sauce, black pepper, garlic, green onion, red pepper, salt, sugar, sesame oil and sesame salt since the early 1900s. Dropwort, egg strips, laver, pine nut (powder), red pepper powder, and red pepper threads were used as garnishes. Tangpyeongchae was made by mixing cheongpomuk with other ingredients and seasonings until the late 1800s. Since the early 1900s Tangpyeongchae has been seasoned first with other ingredients and then mixed cheongpomuk.

• Journal of Korea Water Resources Association
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• v.38 no.5 s.154
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• pp.391-399
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• 2005

The purpose of this study is to evaluate hydrological impact by the land cover change of typhoon damage. For the typhoon RUSA (rainfall 1,402 mm) occurred in 2002 (August $31\;{\sim}$ September 1), satellite images of Landsat 7 ETM+ of September 29, 2000 and Landsat 5 TM of September 11, 2002 were selected, and each land cover was classified for Namdae-cheon watershed $192.7km^2$ located in the middle-eastern part of Korea Peninsula. SCS unit hydrograph for watershed runoff and Muskingum for streamflow routing of WMS HEC-1 was adopted. 30m resolution DEM & hydrological soil group using 1:50,000 soil map were prepared. The model was calibrated using three available data of storm events of 1985 to 1988 based on 1985 land cover condition. To predict the streamflow change by damaged land cover condition, rainfall of 50 years to 500 years frequency were generated using 2nd quantile of Huff method. The damaged land cover condition treated as bare soil surface increased streamflow of $50.1\;m^3/sec$ for 50 years rainfall frequency and $67.6\;m^3/sec$ for 500 years rainfall frequency based on AMC-I condition. There may be some speedy treatment by the government for the next coming typhoon damage.

• Tuberculosis and Respiratory Diseases
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• v.83 no.2
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• pp.141-146
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• 2020

Background: The burden of nontuberculous mycobacterial (NTM) pulmonary disease (PD) is increasing globally. To understand the treatment outcomes and prognosis of NTM-PD, a unified registry is needed. In this project, we aim to construct a multicenter prospective observational cohort with NTM-PD in South Korea (NTM-KOREA). Methods: The primary objective of this study is to analyze treatment outcomes according to the species. In addition, recurrence rate, adverse events, the impact of each drug on treatment outcomes as well as the impact of characteristics of mycobacteriology will be analyzed. The inclusion criteria for the study are as follows: fulfilling the criteria for NTM-PD having one of the following etiologic organisms: Mycobacterium avium complex, M. abscessus subspecies abscessus, M. abscessus subspecies massiliense, or M. kansasii; receiving the first treatment for NTM-PD after enrollment; age >20 years; and consenting to participate in the study. Seven institutions will participate in patient enrollment and about 500 patients are expected to be enrolled. Participants will be recruited from 1 March 2020 until 19 March 2024 and will be observed through 19 March 2029. During the follow-up period, participants' clinical course will be tracked and their clinical data as well as NTM isolates will be collected. Conclusion: NTM-KOREA will be the first nationwide observational cohort for NTM-PD in South Korea. It will provide the information to optimize treatment modalities and will contribute to deeper understanding of the treatment outcomes and long-term prognosis of patients with NTM-PD in South Korea.

• Journal of Digital Convergence
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• v.12 no.11
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• pp.13-21
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• 2014

In this paper, we study on an 'e-Atlas of Society & Culture(e-ASC)', to develop and implement educational courseware for marriage immigrant women, to adapt Korean society. The 'e-ASC' can help cultural adaptation, such as the understanding of Korean people's common values and behaviors and can likewise provide opportunities to contribute to Korean society, for marriage immigrant women living in Korea. E-cultural map is a useful tool for providing educational experiences and sharing a sociocultural homogeneity, using three dimensional space, for both immigrants and residents. The 'e-Atlas of Society & Culture', suggested in this paper, using the notion of an E-cultural map, has a strong point. That is to say, the immigrants have contextual limitations about Korea and Korean culture, caused by some particular events in their motherland. This atlas provides an opportunity to overcome this contextual limitations and to help understand and adapt to Korean society for these immigrants. This 'e-Atlas of Society & Culture' can be an efficient educational tool for immigrants and can help marriage immigrant women understand and adapt Korean social and cultural phenomena. They might have contextual limitations about these phenomena in their motherland.

• Journal of Korean Medicine for Obesity Research
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• v.15 no.1
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• pp.1-8
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• 2015

Objectives: The aim of this study was to evaluate the effectiveness and safety of electroacupuncture for non-alcoholic fatty liver disease (NAFLD). Methods: A randomized, controlled pilot trial was conducted. Twenty-two participants were randomized into one of the two groups: an acupuncture group (n=11) and wait-list group (n=11). The treatment group received 8 sessions of electroacupuncture over 8 weeks. Twenty points (CV4, CV12, both LR14, GB26, ST25, ST34, ST40, ST36, SP4, SP6, LR3) were selected for needling. The control group did not receive acupuncture treatment during study period and followup were done in the 4th and 8th weeks after randomization in both groups. The primary outcome was body fat computed tomography and the secondary outcomes included blood test (aspartate aminotransferase, alanine transferase, triglyceride, total cholesterol, high density lipoproteincholesterol, low density lipoprotein-cholesterol, blood sugar test, ${\gamma}$-guanosine triphosphate) and body composition test (body mass index, weight, body fat mass, body fat rate, waist hip ratio). Safety was assessed at every visit. Results: There was no significant differences in between the experimental group and control group. There were no adverse events. Conclusions: The results suggest that In patients with NAFLD, electroacupuncture treatment did not induce worsening of liver disease and liver function, but it was no improvement symptoms of fatty liver. Study of herb medicine treatments and other acupuncture therapy of NAFLD are required later.

• Journal of Korea Water Resources Association
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• v.36 no.4
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• pp.609-621
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• 2003

The purpose of this study is to evaluate the hydrological impact due to temporal land cover change by gradual urbanization of upstream watershed of Pyeongtaek gauging station of Anseong -cheon. WMS HEC-1 was adopted, and DEM with 200$\times$200m resolution and hydrologic soil group from 1:50,000 soil map were prepared. Land covers of 1986, 1990, 1994 and 1999 Landsat TM images were classified by maximum likelihood method. The watershed showed a trend that forest ＆ paddy areas decreased and urban/residential area gradually increased for the period of 14 years. The model was calibrated at 2 locations (Pyeongtaek and Gongdo) by comparing observed with simulated discharge results for 5 summer storm events from 1998 to 2001. The watershed average CN values varied from 61.7 to 62.3 for the 4 selected years. To identify the impact of streamflow by temporal area change of a target land use, a simple evaluation method that the CN values of areas except the target land use are unified as one representative CN value was suggested. By applying the method, watershed average CN value was affected in the order of paddy, forest and urban/residential, respectively.