• Title/Summary/Keyword: AD model selection

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Diagnosis of Alzheimer's Disease using Combined Feature Selection Method

  • Faisal, Fazal Ur Rehman;Khatri, Uttam;Kwon, Goo-Rak
    • Journal of Korea Multimedia Society
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    • v.24 no.5
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    • pp.667-675
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    • 2021
  • The treatments for symptoms of Alzheimer's disease are being provided and for the early diagnosis several researches are undergoing. In this regard, by using T1-weighted images several classification techniques had been proposed to distinguish among AD, MCI, and Healthy Control (HC) patients. In this paper, we also used some traditional Machine Learning (ML) approaches in order to diagnose the AD. This paper consists of an improvised feature selection method which is used to reduce the model complexity which accounted an issue while utilizing the ML approaches. In our presented work, combination of subcortical and cortical features of 308 subjects of ADNI dataset has been used to diagnose AD using structural magnetic resonance (sMRI) images. Three classification experiments were performed: binary classification. i.e., AD vs eMCI, AD vs lMCI, and AD vs HC. Proposed Feature Selection method consist of a combination of Principal Component Analysis and Recursive Feature Elimination method that has been used to reduce the dimension size and selection of best features simultaneously. Experiment on the dataset demonstrated that SVM is best suited for the AD vs lMCI, AD vs HC, and AD vs eMCI classification with the accuracy of 95.83%, 97.83%, and 97.87% respectively.

Diagnosis of Alzheimer's Disease using Wrapper Feature Selection Method

  • Vyshnavi Ramineni;Goo-Rak Kwon
    • Smart Media Journal
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    • v.12 no.3
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    • pp.30-37
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    • 2023
  • Alzheimer's disease (AD) symptoms are being treated by early diagnosis, where we can only slow the symptoms and research is still undergoing. In consideration, using T1-weighted images several classification models are proposed in Machine learning to identify AD. In this paper, we consider the improvised feature selection, to reduce the complexity by using wrapping techniques and Restricted Boltzmann Machine (RBM). This present work used the subcortical and cortical features of 278 subjects from the ADNI dataset to identify AD and sMRI. Multi-class classification is used for the experiment i.e., AD, EMCI, LMCI, HC. The proposed feature selection consists of Forward feature selection, Backward feature selection, and Combined PCA & RBM. Forward and backward feature selection methods use an iterative method starting being no features in the forward feature selection and backward feature selection with all features included in the technique. PCA is used to reduce the dimensions and RBM is used to select the best feature without interpreting the features. We have compared the three models with PCA to analysis. The following experiment shows that combined PCA &RBM, and backward feature selection give the best accuracy with respective classification model RF i.e., 88.65, 88.56% respectively.

Bayesian bi-level variable selection for genome-wide survival study

  • Eunjee Lee;Joseph G. Ibrahim;Hongtu Zhu
    • Genomics & Informatics
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    • v.21 no.3
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    • pp.28.1-28.13
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    • 2023
  • Mild cognitive impairment (MCI) is a clinical syndrome characterized by the onset and evolution of cognitive impairments, often considered a transitional stage to Alzheimer's disease (AD). The genetic traits of MCI patients who experience a rapid progression to AD can enhance early diagnosis capabilities and facilitate drug discovery for AD. While a genome-wide association study (GWAS) is a standard tool for identifying single nucleotide polymorphisms (SNPs) related to a disease, it fails to detect SNPs with small effect sizes due to stringent control for multiple testing. Additionally, the method does not consider the group structures of SNPs, such as genes or linkage disequilibrium blocks, which can provide valuable insights into the genetic architecture. To address the limitations, we propose a Bayesian bi-level variable selection method that detects SNPs associated with time of conversion from MCI to AD. Our approach integrates group inclusion indicators into an accelerated failure time model to identify important SNP groups. Additionally, we employ data augmentation techniques to impute censored time values using a predictive posterior. We adapt Dirichlet-Laplace shrinkage priors to incorporate the group structure for SNP-level variable selection. In the simulation study, our method outperformed other competing methods regarding variable selection. The analysis of Alzheimer's Disease Neuroimaging Initiative (ADNI) data revealed several genes directly or indirectly related to AD, whereas a classical GWAS did not identify any significant SNPs.

Genetic Parameters and Responses in Growth and Body Composition Traits of Pigs Measured under Group Housing and Ad libitum Feeding from Lines Selected for Growth Rate on a Fixed Ration

  • Nguyen, Nguyen Hong;McPhee, C.P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.8
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    • pp.1075-1079
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    • 2005
  • The main objective of this study is to examine genetic changes in growth rate and carcass composition traits in group housed, ad libitum fed pigs, from lines of Large White divergently selected over four years for high and low post-weaning daily gain on a fixed but restricted ration. Genetic parameters for production and carcass traits were also estimated by using average information-restricted maximum likelihood applied to a multivariate individual animal model. All analyses were carried out on 1,728 records of group housed ad libitum fed pigs, and include a full pedigree of 5,324 animals. Estimates of heritability (standard errors in parentheses) were 0.11 (0.04) for lifetime daily liveweight gain (LDG), 0.13 (0.04) for daily carcass weight gain (CDG) and 0.28 (0.06) for carcass backfat (CFT). Genetic correlations between LDG and CDG were highly positive and between LDG and CFT negative, suggesting that selection for lifetime daily gain under commercial conditions of group housing with ad libitum feeding would result in favourable improvement in carcass traits. CFT showed negative genetic correlations with CDG. Correlated genetic responses evaluated as estimated breeding values (EBVs) were obtained from a multivariate animal model-best linear unbiased prediction analysis. After four years of divergent selection for 6 week post-weaning growth rate on restricted feeding, pigs performance tested on ad libitum feeding in groups exhibited changes in EBVs of 6.77 and -9.93 (g/d) for LDG, 4.25 and -7.08 (g/d) for CDG, and -1.42 and 1.55 (mm) for CFT, in the high and low lines, respectively. It is concluded that selection for growth rate on restricted feeding would significantly improve genetic performance and carcass composition of their descendants when group housed and ad libitum fed as is a common commercial practice.

A Cooperative Transmission Strategy using Entropy-based Relay Selection in Mobile Ad-hoc Wireless Sensor Networks with Rayleigh Fading Environments

  • An, Beong-Ku;Duy, Tran Trung;Kong, Hyung-Yun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.3 no.2
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    • pp.147-162
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    • 2009
  • In this paper, we propose a Cooperative Transmission Strategy using Entropy-based Relay Selection in Mobile Ad-hoc Wireless Sensor Networks(MAWSN) with Rayleigh Fading Environments. The main features and contributions of the proposed cooperative transmission strategy are as follows. First, entropy-based relay selection is used to improve data transmission reliability from a source node to a destination node. Second, we present a theoretical analysis model for the proposed cooperative transmission strategy with the outage probability of the end-to-end performance. The performance of our protocol is evaluated using analysis and simulation.

The Effect of AD Noises Caused by AD Model Selection on Brand Awareness and Brand Attitudes (광고 모델 관련 광고 노이즈가 브랜드 인지도와 브랜드 태도에 미치는 영향)

  • Chung, Jai-Hak;Lee, Sang-Mi
    • Journal of Global Scholars of Marketing Science
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    • v.18 no.3
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    • pp.89-114
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    • 2008
  • Most of the extant studies on communication effects have been devoted to the typical issue, "what types of communication activities are more effective for brand awareness or brand attitudes?" However, little research has addressed another question on communication decisions, "what makes communication activities less effective?" Our study focuses on factors negatively influenced on the efficiency of communication activities, especially of Advertising. Some studies have introduced concepts closely related to our topic such as consumer confusion, brand confusion, or belief confusion. Studies on product belief confusion have found some factors misleading consumers to misunderstand the physical features of products. Studies on brand confusion have uncovered factors making consumers confused on brand names. Studies on advertising confusion have tested the effects of ad models' employed by many other firms for different products on communication efficiency. We address a new concept, Ad noises, which are any factors interfering with consumers exposed to a particular advertisement in understanding messages provided by advertisements. The objective of this study is to understand the effects of ad noises caused by ad models on brand awareness and brand attitude. There are many different types of AD noises. Particularly, we study the effects of AD noises generated from ad model selection decision. Many companies want to employ celebrities as AD models while the number of celebrities who command a high degree of public and media attention are limited. Inevitably, several firms have been adopting the same celebrities as their AD models for different products. If the same AD model is adopted for TV commercials for different products, consumers exposed to those TV commercials are likely to fail to be aware of the target brand due to interference of TV commercials, for other products, employing the same AD model. This is an ad noise caused by employing ad models who have been exposed to consumers in other advertisements, which is the first type of ad noises studied in this research. Another type of AD noises is related to the decision of AD model replacement for the same product advertising. Firms sometimes launch another TV commercial for the same products. Some firms employ the same AD model for the new TV commercial for the same product and other firms employ new AD models for the new TV commercials for the same product. The typical problem with the replacement of AD models is the possibility of interfering with consumers in understanding messages of the TV commercial due to the dissimilarity of the old and new AD models. We studied the effects of these two types of ad noises, which are the typical factors influencing on the effect of communication: (1) ad noises caused by employing ad models who have been exposed to consumers in other advertisements and (2) ad noises caused by changing ad models with different images for same products. First, we measure the negative influence of AD noises on brand awareness and attitudes, in order to provide the importance of studying AD noises. Furthermore, our study unveiled the mediating conditions(variables) which can increase or decrease the effects of ad noises on brand awareness and attitudes. We study the effects of three mediating variables for ad noises caused by employing ad models who have been exposed to consumers in other advertisements: (1) the fit between product image and AD model image, (2) similarity between AD model images in multiple TV commercials employing the same AD model, and (3) similarity between products of which TV commercial employed the same AD model. We analyze the effects of another three mediating variables for ad noises caused by changing ad models with different images for same products: (1) the fit of old and new AD models for the same product, (2) similarity between AD model images in old and new TV commercials for the same product, and (3) concept similarity between old and new TV commercials for the same product. We summarized the empirical results from a field survey as follows. The employment of ad models who have been used in advertisements for other products has negative effects on both brand awareness and attitudes. our empirical study shows that it is possible to reduce the negative effects of ad models used for other products by choosing ad models whose images are relevant to the images of target products for the advertisement, by requiring ad models of images which are different from those of ad models in other advertisements, or by choosing ad models who have been shown in advertisements for other products which are not similar to the target product. The change of ad models for the same product advertisement can positively influence on brand awareness but positively on brand attitudes. Furthermore, the effects of ad model change can be weakened or strengthened depending on the relevancy of new ad models, the similarity of previous and current ad models, and the consistency of the previous and current ad messages.

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A Study on the Visual Precautions of Soju Advertising Posters Using Eye Tracking (아이트래킹을 활용한 소주광고 포스터의 시각적 주의에 관한 연구)

  • Hwang, Mi Kyung;Kwon, Mahn Woo;Park, Min Hee;Kim, Chee Yong
    • Journal of Korea Multimedia Society
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    • v.23 no.2
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    • pp.368-375
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    • 2020
  • In this study, the area of interest(AOI) of Soju ad poster was tracked for analysis the time to frist fixation, the average of fixation duration and count by the study indexes. As a result of the analysis, Visual attention was higher the face than the body shape of the ad model. This means "when we look at printed ads, we see picture elements first, not language one" but language elements can't be overlooked either. Also, the importance of the model role could be verified by measuring the visual attention on the Soju ad poster. Based on the results of this study, if further research on ad posters is carried out and scientific and quantitative interpretation methods are presented, it can be used as product marketing data that can be reflected in ad model selection and poster design.

Cooperation Models and Cooperative Routing for Exploiting Hop-by-Hop Cooperative Diver sity in Ad Hoc Networks

  • Shin, Hee-Wook;Moh, Sang-Man;Chung, Il-Yong
    • Journal of Korea Multimedia Society
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    • v.14 no.12
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    • pp.1559-1571
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    • 2011
  • In wireless ad hoc networks, nodes communicate with each other using multihop routed transmission in which hop-by-hop cooperative diversity can be effectively employed. This paper proposes (i) two cooperation models for per-link cooperation (PLC) and per-node cooperation (PNC) for exploiting cooperative diversity in wireless ad hoc networks and (ii) a cooperative routing algorithm for the above models in which best relays are selected for cooperative transmission. First, two cooperation models for PLC and PNC are introduced and represented as an edge-weighted graph with effective link quality. Then, the proposed models are transformed into a simplified graph and a cooperative routing algorithm with O(n2) time is developed, where n is the number of nodes in the network. The effectiveness of the algorithm is confirmed for the two cooperation models using simulation.

Design of the Fuzzy-based Mobile Model for Energy Efficiency within a Wireless Sensor Network

  • Yun, Dai Yeol;Lee, Daesung
    • Journal of information and communication convergence engineering
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    • v.19 no.3
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    • pp.136-141
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    • 2021
  • Research on wireless sensor networks has focused on the monitoring and characterization of large-scale physical environments and the tracking of various environmental or physical conditions, such as temperature, pressure, and wind speed. We propose a stochastic mobility model that can be applied to a MANET (Mobile Ad-hoc NETwork). environment, and apply this mobility model to a newly proposed clustering-based routing protocol. To verify its stability and durability, we compared the proposed stochastic mobility model with a random model in terms of energy efficiency. The FND (First Node Dead) was measured and compared to verify the performance of the newly designed protocol. In this paper, we describe the proposed mobility model, quantify the changes to the mobile environment, and detail the selection of cluster heads and clusters formed using a fuzzy inference system. After the clusters are configured, the collected data are sent to a base station. Studies on clustering-based routing protocols and stochastic mobility models for MANET applications have shown that these strategies improve the energy efficiency of a network.

An Experimental Study for the Mechanical Properties of Model Ice Grown in a Cold Room (Cold Room을 이용한 모형빙의 재료특성에 관한 실험적 연구)

  • Kim, Jung-Hyun;Choi, Kyung-Sik;Jeong, Seong-Yeob;Seo, Young-Kyo;Cho, Seong-Rak;Lee, Chun-Ju
    • Journal of Ocean Engineering and Technology
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    • v.22 no.3
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    • pp.64-70
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    • 2008
  • A full-scale field experiment is an important part in the design of ships and offshore structures. Full-scale tests in the ice-covered sea, however, are usually very expensive and difficult tasks. Model tests in a refrigerated ice tank may substitute this difficulty of full-scale field tests. One of the major tasks to perform proper model tests in an ice towing tank is to select a realistic material for model ice which shows correct similitude with natural sea ice. This study focuses on the testing material properties and the selection of model ice material which will be used in an ice model basin. The first Korean ice model basin will be constructed at the Maritime & Ocean Engineering Research Institute (MOERI) in 2009. With an application to the MOERI ice model basin, in this study the material properties of EG/AD/S model ice of IOT (Institute for Ocean Technology) Canada, were tested. Through comprehensive bending tests, the elastic modulus and the flexural strength of EG/AD/S model ice were evaluated and the results were compared with published test results from Canada. Instead of using an ice model basin, a cold room facility was used for making a model ice specimen. Since the cold room adopts a different freezing procedure to make model ice, the strength of the model ice specimen differs from the published test results. The reason for this difference is discussed and the future development for a making model ice is recommended.