• Journal of Life Science
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• v.21 no.3
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• pp.473-479
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• 2011

Adenylyl cyclase (AC) catalyzes the formation of cyclic AMP (cAMP) from ATP. The cAMP produced by AC serves as a secondary messenger in a variety of signal transduction pathways, and controls various cellular functions in many organisms. ACs can be grouped into six classes based on their primary amino acid sequences. Eukaryotes and mycobacteria contain only members of class III AC. The catalytic cyclase domains of class III AC are active as dimers: mammalian ACs, which are composed of a single polypeptide with two catalytic cyclase domains, form the active site as a result of intramolecular dimerization of the catalytic cyclase domains. In contrast, mycobacterial ACs function as homodimers, since their polypeptides contain a single catalytic cyclase domain. Six amino acids are required for the catalytic activity of class III AC - two aspartate residues, a lysine-aspartate pair and an arginine-asparagine pair. 16 ACs belonging to the class III were identified in Mycobacterium tuberculosis H37Rv, and their characteristics are reviewed.

• Journal of Korean Society on Water Environment
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• v.22 no.2
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• pp.328-332
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• 2006

Fe(III)-impregnated activated carbon (Fe-AC) was applied in the treatment of synthetic wastewater containing Cu(II). To investigate the stability of Fe-AC at acidic condition, dissolution of Fe was studied with a variation of solution pH ranging from 2 to 4. Fe-AC was unstable at pH 2, showing a gradual increase of the dissoluted Fe as reaction time increased, while negligible amount of Fe was dissoluted above pH 3. This stability test suggests the applicability of Fe-AC in the treatment of wastewater above pH 3. Adsorption capacity of Cu(II) onto activated carbon (AC) and Fe-AC was investigated in a batch and a column test. In the adsorption kinetics, rapid adsorption of Cu(II) onto AC and Fe-AC was noted at initial reaction time and then reached a near complete equilibrium after 6 hrs. Adsorption trends of Cu(II) onto AC and Fe-AC were similar, showing an increased Cu(II) adsorption at higher pH. Compared with AC, Fe-AC showed a greater Cu(II) adsorption over the entire pH range studied in this research. From the adsorption isotherm obtained with variation of the concentration of Cu(II), the maximum adsorption capacity was identified as 61,700 mg/kg.

• Journal of Electrical Engineering and Technology
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• v.3 no.2
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• pp.152-161
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• 2008

This paper deals with a new wave shaping technique for cost effective harmonic mitigation in ac-dc converter feeding Vector Controlled Induction Motor Drives(VCIMD's) for improving power quality at the point of common coupling(PCC). The proposed harmonic mitigator consists of a polygon connected autotransformer based twelve-pulse ac-dc converter and a small rating passive shunt filter tuned for $11^{th}$ harmonic frequency. This ac-dc converter eliminates the most dominant $5^{th},\;7^{th},\;and\;11^{th}$ harmonics and imposes the reduction of other higher order harmonics from the ac main current, thereby improving the power quality at ac mains. The design of autotransformer is carried out for the proposed ac-dc converter to make it suitable for retrofit applications, where presently a 6-pulse ac-dc converter is used. The effect of load variation on VCIMD is also studied to demonstrate the effectiveness of the proposed ac-dc converter in a wide operating range of the drive. Experimental results obtained on the developed laboratory prototype of the proposed harmonic mitigator are used to validate the model and design of the ac-dc converter.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2004.05b
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• pp.517-520
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• 2004

In this paper, a PWM Cuk AC-AC converter is modelled by using complex circuit DQ transformation whereby the equivalent model is obtained which has the complete information of the Cuk converter. Using the model, the dynamicc characteristics equations such as state equations is analytically obtained. Finally, the PSIM simulation show the validity of the modelling and analysis.

• Korean Journal of Ophthalmology
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• v.32 no.6
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• pp.483-487
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• 2018

Purpose: To compare the characteristics and surgical outcomes in patients with tenacious proximal fusion (TPF) and high accommodative convergence/accommodation ratio (AC/A) types of intermittent exotropia. Methods: This study retrospectively enrolled 40 patients with intermittent exotropia, 23 with TPF and 17 with high AC/A. Binocular function was evaluated by Worth's 4-dot test. Patients underwent lateral rectus recession, and surgical outcomes were compared. Surgical success was defined as less than ${\pm}10$ prism diopters (PD) at 12 months postoperatively. Results: The proportion of diplopia at near, evaluated by Worth's 4-dot test, was significantly higher in patients with high AC/A than in those with TPF (35.3% vs. 4.3%, p = 0.029). The mean preoperative angles of deviation in TPF and high AC/A types were $28.3{\pm}4.4$ and $28.8{\pm}4.5PD$ at distances, and $14.7{\pm}4.2$ and $15.1{\pm}4.1PD$ at near. Twelve months after surgery, the mean angles of deviation in TPF and high AC/A types were $2.9{\pm}9.8$ and $1.2{\pm}9.6PD$, respectively, at distance and $1.7{\pm}7.7$ and $-1.3{\pm}11.3PD$ at near. The surgical success rates were similar in the TPF and high AC/A types (74.0% vs. 64.7%). Five (21.7%) patients with TPF and 2 (11.8%) with high AC/A type experienced recurrence, with consecutive esotropia occurring in 1 (4.3%) patient with TPF and 4 (23.5%) patients with high AC/A. Conclusions: The proportion of diplopia at near was higher in patients with high AC/A type than in those with TPF intermittent exotropia. However, the surgical success rates were not significantly different between the types.

• Biomedical Science Letters
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• v.28 no.2
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• pp.109-119
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• 2022

Histone proteins can be modified by the addition of acetyl group or methyl group to specific amino acids. The modifications have different distribution patterns in chromatin. Recently, histone modifications are studied based on ChIP-seq data, which requires reasonable analysis of sequencing data depending on their distribution patterns. Here we have analyzed histone H3K27ac and H3K27me3 ChIP-seq data and it showed that the H3K27ac is enriched at narrow regions while H3K27me3 distributes broadly. To properly analyze the ChIP-seq data, we called peaks for H3K27ac and H3K27me3 using MACS2 (narrow option and broad option) and SICER methods, and compared propriety of the peaks using signal-to-background ratio. As results, H3K27ac-enriched regions were well identified by both methods while H3K27me3 peaks were properly identified by SICER, which indicates that peak calling method is more critical for histone modifications distributed broadly. When ChIP-seq data were compared in different sequencing depth (15, 30, 60, 120 M), high sequencing depth caused high false-positive rate in H3K27ac peak calling, but it reflected more properly the broad distribution pattern of H3K27me3. These results suggest that sequencing depth affects peak calling from ChIP-seq data and high sequencing depth is required for H3K27me3. Taken together, peak calling tool and sequencing depth should be chosen depending on the distribution pattern of histone modification in ChIP-seq analysis.

• Journal of Korea Foundry Society
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• v.20 no.1
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• pp.21-28
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• 2000

Ni and Ni-Cr porous metals which are estimated to be easy to fabricate by squeeze casting are used as strengtheners for composite materials. As a matrix material, Al-7%wtSi-0.3 wt%Mg(AC4C) has been used. In case of Ni/AC4C and Ni-Cr/AC4C composite, $750^{\circ}C$ melt temperature and minimum 25 MPa squeezing pressure are needed to produce sound composite materials. The observation of interfacial reaction zone at various heat treatment condition showed that solutionizing temperature of above 520^{\circ}C$, the interfacial reaction zone increased proportionally with increasing heat treatment tim and reaction products formed by interfacial reaction are mainly composed of $Al_3Ni$ and $Al_3Ni_2$ phases. The tensile strength of Ni/AC4C and Ni-Cr/AC4C composite is lower than the matrix metal and this can be explained by the brittle intermetallic compounds formed at the interface of Ni and Ni-Cr reinforcements. But the properies of hardness, wear resistance and thermal expansion are better than the matrix due to the strengthening effect of Ni-Cr porous metals.

• The Transactions of the Korean Institute of Power Electronics
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• v.15 no.3
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• pp.207-217
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• 2010

Recently, the use of DC power increased due to the increased use of digital load. Power factor of input current decrease and input current harmonics increase, and conversion loss which is occurred in the AC / DC converter is a problem to provide the proper DC voltage to the device equipped with an internal AC / DC converter. Hybrid system supplies the AC power and DC power to AC load (motor load and the transformer load) and DC loads (computers, TV, LED fluorescent light) at the same time it supplies the renewable energy and utility energy taken power from Utility to user for improving the efficiency and renewable energy improvements in ease of use. This paper studies DC characteristics of traditional AC load for Hybrid distributions.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.15 no.4
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• pp.223-229
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• 2022

In this paper, the ignition trans used in boilers was studied. Regardless of the change in the ignition rod length and the ignition rod gap, the output frequency was measured between 59.5 and 61.3 Hz, and it was found that the low frequency circuit operated normally. When the ignition rod gap changed by 2 to 10 mm, the ignition rod length was measured from 2.8A to 3.45A at 30cm. The ignition rod length was measured from 9.37 A to 14.5 A at 500 cm and from 13.2 A to 32.6 A at 1000 cm. As the ignition rod length and the ignition rod gap increased, the current increased. As a result of measuring the secondary coil output voltage. The ignition rod length was measured from AC 0.84 kV to AC 1.75 kV at 30 cm, AC 1.17 kV to AC 1.944 at 500 cm, and AC 1.4 kV to AC 7.18 kV at 1000 cm. As the ignition rod length and the ignition rod gap increased, the output voltage of the secondary coil also increased. As a result of measuring the output voltage of the ignition trans, the ignition rod length was measured from DC 1.11 kV to DC 1.57 kV at 30cm, DC 2.49 kV to DC 3.72 kV at 500cm, and DC 3.78 kV to DC 9.42 kV at 1000cm, and the power voltage increased as the ignition rod length and interval increased.

• Journal of Electrical Engineering and Technology
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• v.10 no.1
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• pp.165-175
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• 2015

Energy storage system has been widely applied in power distribution sectors as well as in renewable energy sources to ensure uninterruptible power supply. This paper presents a model predictive algorithm to control a bidirectional AC-DC converter, which is used in an energy storage system for power transferring between the three-phase AC voltage supply and energy storage devices. This model predictive control (MPC) algorithm utilizes the discrete behavior of the converter and predicts the future variables of the system by defining cost functions for all possible switching states. Subsequently, the switching state that corresponds to the minimum cost function is selected for the next sampling period for firing the switches of the AC-DC converter. The proposed model predictive control scheme of the AC-DC converter allows bidirectional power flow with instantaneous mode change capability and fast dynamic response. The performance of the MPC controlled bidirectional AC-DC converter is simulated with MATLAB/Simulink(R) and further verified with 3.0kW experimental prototypes. Both the simulation and experimental results show that, the AC-DC converter is operated with unity power factor, acceptable THD (3.3% during rectifier mode and 3.5% during inverter mode) level of AC current and very low DC voltage ripple. Moreover, an efficiency comparison is performed between the proposed MPC and conventional VOC-based PWM controller of the bidirectional AC-DC converter which ensures the effectiveness of MPC controller.