• Korean Journal of Food Science and Technology
• /
• v.46 no.5
• /
• pp.616-621
• /
• 2014

This study was conducted to investigate the detoxification effect of extract from soy-sprout grown using high concentrated oxygen water extract (SE) against alcohol-induced hangover in male Sprague-Dawley (SD) rats. The rats were orally administered with different concentrations of SE beverage [26, 260 and 2,000 mg/kg body weight (b.w.)] and, after 30 min, with alcohol at a dose of 3 g/kg b.w. After 1 and 3 h of alcohol administration, blood was collected from the retro-orbital plexus, while after 5 h, blood was collected from the heart. In the 2,000 mg/kg b.w. SE group, the concentration of blood alcohol was significantly reduced after 1-5 h of alcohol loading as compared with that in the other groups. In addition, the blood acetaldehyde concentration was reduced by SE (2,000 mg/kg b.w.). These results suggest that SE beverage can alleviate alcohol hangover symptoms by stimulating the activities related to hepatic alcohol-metabolizing enzymes.

• Korean Journal of Clinical Laboratory Science
• /
• v.51 no.4
• /
• pp.514-520
• /
• 2019

This study investigated the improved lipid metabolism effect of 3T3-L1 cells induced by adipocytes using the dichloromethane (DCM) fraction in the organic solvent extract of Wassong (Orostachys japonicus). To confirm the cell cytotoxicity, each of 6 fractions of organic solvent extracts (EtOH, Hexane, DCM, EtOAc, BuOH, and H₂O) was examined using MTS assay. As a result, it was confirmed that the DCM extract was stable over the whole range of concentrations, and a DCM fraction was used to confirm the improved lipid metabolism effect. Lipid excretion was measured to confirm the change of lipid metabolism. 3T3-L1 cells induced by adipocytes were treated with DCM extract and stained with oil-red O to evaluate lipid accumulation. As a result, it was confirmed that the lipid efflux was significantly improved. In order to confirm the mechanism of lipid efflux, the mRNA expressions of ABCA1 and ABCG1, which are lipid transport proteins, were confirmed by real-time PCR. Therefore, the present study confirmed that the DCM extract from Orostachys japonicus has the effect of improving the lipid metabolism on 3T3-L1 adipocytes. In addition, the results of this study will be used as the basis for the development of functional foods using Orostachys japonicus and also for conducting research on the detailed mechanisms.

• Food Science of Animal Resources
• /
• v.30 no.2
• /
• pp.286-290
• /
• 2010

Angiotensin-converting enzyme (ACE) inhibitory activity and production optimization of ovotransferrin hydrolysates were studied. Ovotransferrin was hydrolyzed by several enzymes (protamex, alcalase, trypsin, pepsin, neutrase, and flavorzyme) and acid (0.03 N HCl). Ovotransferrin hydrolysate reduced ACE activity by 60.2%, 55.8%, and 42.6% when treated with trypsin, acid, and pepsin, respectively. Trypsin was selected for production of peptide having maximum AC inhibitory effect, which was greatest with 7 h hydrolysis. Central composite design determined that optimum composition of ACE inhibitory substances using substrate concentration of 20-35%, temperature of $35-55^{\circ}C$, and pH of 6.0-8.0. The optimum composition was 1% trypsin, substrate concentration of 26.32%, $51.29^{\circ}C$, and pH 6.32. Under this conditions, a maximum ACE inhibitory effect of 69.1% was evident, similar to the predicted value.

• Proceedings of the KWS Conference
• /
• 2009.11a
• /
• pp.119-119
• /
• 2009

인버터 DC 저항용접의 적용성 증대 : 인버터 DC 저항용접 공법이 SPOT, PROJECTON, SEAM, BUTT 등의 공정에 다양하게 적용되어 저항용접 현장에서 고효율, 친환경적 용접 환경을 만드는데 일조 하고 있다. 특히 자동차의 경량화, 충돌내성 증대, 진동 및 내구성 증대, 공간활용 극대화, 새로운 Design 개념 적용 등의 산업전반에 걸쳐 나타나는 신 Trends로 고 장력 철재의 적용 범위가 확대되고 HSS(High Strength Steel), EHSS(Extra High Strength Steel), UHSS (Ultra High strength Steel ; Hot - Formed Steel )등 다양한 철판의 SPOT 저항용접이 필요하게 되었다. 기존의 AC 단상용접의 전력 특성 상 통전 중 무 통전 시간 과 높은 PEAK 전력, 단상 대 전력 소모로 인한 전력 DROP 등의 문제로 인하여 신소재의 용접 시 매우 많은 Spatter가 발생하고, 높은 용접품질의 확보가 어려워 지므로 이를 대체하기 위한 공법으로 MFDC ( 인버터 DC 저항용접공법 )이 적용되고 있다. 인버터 DC 저항용접의 적응제어 : MFDC라는 높은 효율의 용접 전력원이 확보 됨에도 불구하고 용접현장에서는 원 자재, 도금 등의 품질 산포, 프레스 물의 가공산포, 공기압 산포, 전극 과열 및 마모 등의 요인에 의하여 저항용접 산포가 발생하고 있다. 이는 인위적인 조작이 어렵고 불규칙적이며, 어디서나 산재하고 있는 문제이다. 이를 용접전력 제어 법으로 개선하여 일정한 용접성을 확보하기 위한 노력이 적응제어 기법이다. 정 전류, 정 전력 제어는 정량 제어로 용접 물을 비롯한 용접부의 변화와는 관계없이 설정된 일정량의 전력을 공급하기만 하는데 반하여 적응제어는 적절한 용접 작업 시의 용접 물의 상태, 전극의 가압, 표면 상태 등에 따른 변화 페턴을 기억하고 이후 진행되는 용접에 대하여 정상 페턴과의 차이를 감지 이를 보상하므로 고품질의 용접성을 보장하는 제어기법이다. 따라서 다양한 용접 산포 유발 요인에 의해 용접부의 변화가 발생한다 하여도 그 변화를 감지 하고 적절한 용접전력을 공급한다면 고품질의 용접성을 확보하는데 유용한 공법이 될 수 있다. 인버터 DC 저항용접의 SPC 관리 : SPOT 용접 시 획득할 수 있는 다양한 파라메터에 대하여 모니터링 하고 이 자료를 data 화 하여 품질 관리에 응용하게 되면 양산라인에서 반복적으로 발생되는 문제점을 확인 할 수 있고 이를 통계적 방법으로 추적 개선해 나간다면 용접 불량 감소 및 생산성 향상에 도움이 되며 작업자의 공정 능력 향상 및 기업의 기술축적에도 높은 기여를 할 수 있을 것이다. 용접 적응제어와 다양한 파라메터 모니터링이 한 system에서 이루어 질 때 높은 용접성 확보와 불량률 감소, 원가절감, 생산성 향상 등의 효과가 극대화 될 것이다.

• Korean Journal of Breeding Science
• /
• v.41 no.4
• /
• pp.564-567
• /
• 2009

"Boseog" is a new japonica rice cultivar developed from the three way cross of Kinuhikari//HR19621AC6/Sobibyeo and registered by the rice breeding team of Department of Rice and Winter Cereal Crop, NICS, RDA in 2008. This cultivar has about 110 days of growth duration from transplanting to harvesting in northern plain, northern and southern mid-mountainous area of Korea. This cultivar is about 72 cm in culm length and tolerant to lodging. In the reaction to biotic and abiotic stresses, it shows resistance to leaf blast, but susceptibility to bacterial blight, virus diseases and insect pests. The milled rice of "Boseog" exhibits translucent, relatively clear non-glutinous endosperm and midium short grain. It has similar amylose content(18.0%), lower protein content(6.3%), and similar palatability of cooked rice compared to Odaebyeo. The milled rice yield of this variety is about 5.03 MT/ha in local adaptability test. "Boseog" would be adaptable for ordinary transplanting in northern plain, mid-mountainous and southern mountainous area of Korea.

• Bulletin of the Korean Chemical Society
• /
• v.21 no.11
• /
• pp.1125-1132
• /
• 2000

The pH effect of the precursor solution on the preparation of $LiCoO_2$ by a solution phase reaction containing malonic acid was carried out. Layered $LiCoO_2$ powders were obtained with the precursors prepared at the different pHs (4, 7, and 9) and heat-treated at $700^{\circ}C(LiCoO_2-700)$ or $850^{\circ}C(LiCoO_2-850)$ in air. pHs of the media for precursor synthesis affects the charge/discharge and electrochemical properties of the $LiCoO_2electrodes.$ Upon irrespective of pH of the precursor media, X-ray diffraction spectra recorded for $LiCoO_2-850$ powder showed higher peak intensity ratio of I(003)/I(104) than that of $LiCoO_2-700$, since the better crystallization of the former crystallized better. However, $LiCoO_2$ synthesized at pH 4 displayed an abnormal higher intensity ratio of I(003)/I(104) than those synthesized at pH 7 and 9. The surface morphology of the $LiCoO_2-850$ powders was rougher and more irregular than that of $LiCoO_2-700$ made from the precursor synthesized at pH 7 and 9. The $LiCoO_2electrodes$ prepared with the precursors synthesized at pH 7 and 9 showed a better electrochemical and charge/discharge characteristics. From the AC impedance spectroscopic experiments for the electrode made from the precursor prepared in pH 7, the chemical diffusivity of Li ions (DLi+) in $Li0.58CoO_2determined$ was 2.7 ${\times}$10-8 $cm^2s-1$. A cell composed of the $LiCoO_2-700$ cathode prepared in pH 7 with Lithium metal anode reveals an initial discharge specific capacity of 119.8 mAhg-1 at a current density of 10.0 mAg-1 between 3.5 V and 4.3 V. The full-cell composed with $LiCoO_2-700$ cathode prepared in pH 7 and the Mesocarbon Pitch-based Carbon Fiber (MPCF) anode separated by a Cellgard 2400 membrane showed a good cycleability. In addition, it was operated over 100 charge/discharge cycles and displayed an average reversible capacity of nearly 130 mAhg-1.

• Ceramist
• /
• v.21 no.4
• /
• pp.378-387
• /
• 2018

The optimal fabrication conditions for $Gd_{0.1}Ce_{0.9}O_{2-{\delta}}$(GDC) buffer layer and $La_{0.6}Sr_{0.4}Co_{0.2}Fe_{0.8}O_{3-{\delta}}$ (LSCF) cathode on 1mol% $CeO_2-10mol%\;Sc_2O_3$ stabilized $ZrO_2$ (CeScSZ) electrolyte were investigated for application of IT-SOFCs. GDC buffer layer was used in order to prevent undesired chemical reactions between LSCF and CeScSZ. These experiments were carried out with $5{\times}5cm^2$ anode supported unit cells to investigate the tendencies of electrochemical performance, Microstructure development and interface reaction between LSCF/GDC/CeScSZ along with the variations of GDC buffer layer thickness, sintering temperatures of GDC and LSCF were checked, respectively. Electrochemical performance was analyzed by DC current-voltage measurement and AC impedance spectroscopy. Microstructure and interface reaction were investigated by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Although the interfacial reaction between these materials could not be perfectly inhibited, We found that the cell, in which $6{\mu}m$ GDC interlayer sintered at $1200^{\circ}C$ and LSCF sintered at $1000^{\circ}C$ were applied, showed good interfacial adhesions and effective suppression of Sr, thereby resulting in fairly good performance with power density of $0.71W/cm^2$ at $800^{\circ}C$ and 0.7V.

• Clinical and Experimental Reproductive Medicine
• /
• v.32 no.3
• /
• pp.279-286
• /
• 2005

Objective: Although several genetic factors have been associated with defects in human spermatogenesis, the unambiguous causative genes have not been elucidated. The male infertility by haploinsufficiency of PRM1 or PRM2 has been reported in mouse model. The aim of this study was to identify the single nucleotide polymorphisms (SNPs) of PRM1 and PRM2, related to the genotype of Korean infertile men. Methods: Genomic DNAs were extracted from peripheral bloods of infertile men with oligozoospermia or azoospermia, and analyzed using polymerase chain reaction (PCR) and direct sequencing. We carried out the direct sequencing analysis of amplified fragments in PRM1 (557 nucleotides from -42 to 515) and PRM2 (599 nucleotides from 49 to 648) genes, respectively. Results: Three SNPs of coding region in the PRM1 gene was found in the analysis of 130 infertile men. However, the SNPs at a133g (aa 96.9%, ag 3.1% and gg 0.0%), c160a (cc 99.2%, ca 0.8% and aa 0.0%) and c321a (cc 56.9%, ca 35.4% and aa 7.7%) coded the same amino acids, in terms of silence phenotypes. On the other hand, as results of the PRM2 gene sequencing in 164 infertile men, only two SNPs, g398c (gg 62.2%, gc 31.1% and ga 6.7%) and a473c (aa 63.4%, ac 29.9% and cc 6.7%), were identified in the intron of the PRM2 gene. Conclusions: There was no mutation and significant SNPs on PRM1 and PRM2 gene in Korean infertile men. These results suggest that the PRM1 and PRM2 genes are highly conserved and essential for normal fertility of men.

• Elastomers and Composites
• /
• v.38 no.3
• /
• pp.227-234
• /
• 2003

Silicone composites for high voltage insulator (HVI SC) were prepared by adding aluminum trihydrate(ATH) treated by surface treatment agent to base silicone compound at the ratio oi 100:20, 100:40, 100:60, 100:80, and 100:100, respectively And also, ATH was treated by various surface treatment agents, such as stearic arid, acryl silane, and vinyl silane under compounding process. Mechanical properties and electrical properties were investigated for the various contents of ATH and surface-treatment agents. Mechanical properties such as tensile strength, elongation, and tear strength decreased as the load of ATH increased. Volume resistivity, AC break down strength, and tracking resistance for HVI SC containing ATH treated by vinyl silane were better than those for HVI SC containing ATH treated by other surface treatment agents, such as stearic acid and acryl silane. Polymer-filler interaction of silicone composites according to surface treatment agents was studied by measuring bound rubber contend(BR). From the experimental results, BR of silicone composite containing ATH treated with vinyl silane was higher than that of the others. The degree of rule for silicone composite was investigated using Rheometer. Maximum torque of silicone composites contaning ATH treated with vinyl silane was higher than that of silicone composite contaning ATH treated with other surface agents.

• Korean Journal of Soil Science and Fertilizer
• /
• v.18 no.4
• /
• pp.336-347
• /
• 1985

Soils and rice plants subject to smoke from the Jang-hang Smelter were samples at two depths to assess the nature and extend of Cd, Cu, Pb, and Zn contamination, particularly with respect to distance from pollution source. Soils at east site within 1km of the center of the smelter were highly contaminated with Cd, Cu, Pb, and Zn. Metal levels in the smoke-polluted area were higher in surface soil than in subsurface soil, and decreased rapidly with distance reaching nearly background levels at 5km from pollution source. A position correlation was found between contents of total and 0.1 N HCl-extractable, or 1.0N $CH_3COONH_4$- extractable heavy metals in surface soils of pollution. Contents of heavy metals in soils were positively correlated with soil organic matter and cation exchange capacity. The contents of heavy metals in brown rice collected from the paddy field around the Jang-hang Smelter were in the range of 0.23-1.33 ppm for Cd, 2.39-6.25 for Cu, 0.95-8.32 ppm for Pb and 14.60-27.31 for Zn. The contents of Cd, Cu, and Zn in rice straw were positively correlated with those in the brown rice. Negative correlation was found between the contents of Cd, Cu, Pb, and Zn in brown rice and the distance from the source.