• Journal of Korean Neurosurgical Society
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• v.58 no.5
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• pp.487-490
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• 2015

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a relapsing-remitting disorder for which steroid administration is a key to control the progression. CLIPPERS can exhibit radiological features similar to malignant lymphoma, whose diagnosis is confounded by prior steroid administration. We report a case of CLIPPERS accompanied by abnormal elevation of ${\beta}-2$ microglobulin in the cerebrospinal fluid (CSF). A 62-year-old man started to experience numbness in all fingers of his left hand one year ago, which gradually extended to his body trunk and legs on both sides. Magnetic resonance imaging demonstrated numerous small enhancing spots scattered in his brain and spinal cord. CSF levels of ${\beta}-2$ microglobulin were elevated; although this often indicates central nervous system involvement in leukemia and lymphoma, the lesions were diagnosed as CLIPPERS based on the pathological findings from a biopsy specimen. We emphasize the importance of biopsy to differentiate between CLIPPERS and malignant lymphoma because the temporary radiological response to steroid might be the same in both diseases but the treatment strategies regarding the use of steroid are quite different.

• Food Science of Animal Resources
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• v.36 no.4
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• pp.487-493
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• 2016

The antimicrobial activity of bovine lactoferrin hydrolysates (bLFH) was measured against Pseudomonas strains (P. syringae and P. fluorescens) in vitro. To compare susceptibility to bLFH, minimal inhibitory concentration (MIC) values were determined using chemiluminescence assays and paper disc plate assays. Antimicrobial effect against P. fluorescens was not observed by either assay, suggesting that bLFH did not exhibit antimicrobial activity against P. fluorescens. However, a significant inhibition of P. syringae growth was observed in the presence of bLFH. The addition of bLFH in liquid or solid medium inhibited growth of P. syringae in a dose-dependent manner. Furthermore, a bLFH peptide with antimicrobial activity toward P. syringae was isolated and identified. The N-terminal amino acid sequences of thus obtained antimicrobial bLFH peptides were analyzed by a protein sequencer and were found to be Leu-Arg-Ile-Pro-Ser-Lys-Val-Asp-Ser-Ala and Phe-Lys-Cys-Arg-Arg-Trp-Gln-Trp-Arg-Met. The latter peptide sequence is known to be characteristic of lactoferricin. Therefore, in the present study, we identified a new antimicrobial peptide against P. syringae, present within the N-terminus and possessing the amino acid sequence of Leu-Arg-Ile-Pro-Ser-Lys-Val-Asp-Ser-Ala.

• Journal of Magnetics
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• v.18 no.4
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• pp.487-493
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• 2013

The automotive industry is showing widespread interest in belt-driven electric motor-assisted (e-Assist) systems. A belt-driven assist system (BAS) starts and assists the combustion engine in place of the conventional generator. In this study, a water-cooled wound rotor synchronous motor (WRSM) for the e-Assist system was designed and analyzed. The performance of the WRSM was compared with that of an interior permanent magnet synchronous motor (IPMSM). The WRSM efficiency can be improved for the BAS by adjusting the field flux at high speeds. The field current map to obtain the maximum efficiency based on the speed and torque was developed. To control the field flux via field current control in the WRSM, a general H-bridge circuit was added to the WRSM inverter to get the rapid current response in the high-speed region; the characteristics were compared with the chopper circuit. A WRSM developed for the belt-driven e-Assist system and a prototype 115 V power electronic converter to drive the WRSM were tested with a 900 cc combustion engine. The test results showed that the WRSM-type e-Assist system had good characteristics and could successfully start and assist the 900 cc combustion engine.

• Journal of Power Electronics
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• v.13 no.3
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• pp.487-496
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• 2013

The three-phase synchronous reference frame phase-locked loop (SRF-PLL) is widely used for synchronization applications in power systems. In this paper, a new control strategy for three-phase grid-connected LCL inverters without a PLL is presented. According to the new strategy, a current reference can be generated by using the instantaneous power control scheme and the proposed positive-sequence voltage detector. Through theoretical analysis, it is indicated that a high-quality grid current can be produced by introducing the new control strategy. In addition, a kind of independent control for reactive power can be achieved under unbalanced and distorted grid conditions. Finally, the excellent performance of the proposed control strategy is validated by means of simulation and experimental results.

• Journal of the Society of Naval Architects of Korea
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• v.42 no.5 s.143
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• pp.487-492
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• 2005

The structural intensity analysis, which calculates vibration energy flow from vibratory velocity and internal force of a structure, can give information on sources' power, dominant transmission path and sink of vibration energy. In this study, we present a system for structural intensity analysis and visualization to apply for anti-vibration design of ship structures. The system calculates structural intensity from the results of forced vibration analysis and visualize the intensity using a general purpose finite element analysis program MSC/Nastran and its pre- and post-processor program. To demonstrate the analysis and visualization capability of the presented system, we show and discuss the results of structural intensity analysis for a cross-stiffened plate and a 70,500 OW crude oil tanker

• The Korean Journal of Applied Statistics
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• v.18 no.2
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• pp.487-497
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• 2005

The instruction assessment, which can be a tool to realize a class of high quality, evaluates instruction system and process. The result data of the instruction assessment is analysed and used to reorganize lecture contents or to improve teaching method. It enhances qualitative level of university education. The goal of the instruction assessment is to be a tool that provides high qualitative education to raise students' satisfaction. It is important to improve education service quality through instruction assessment as a useful tool for measuring service quality. The suggestion of valid tool for improving instruction service quality is described in this paper.

• The Korean Journal of Applied Statistics
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• v.23 no.3
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• pp.487-495
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• 2010

This paper develops a goodness of fit test statistic to test if the progressively Type II censored sample comes from an exponential distribution with origin known. The test is based on normalizing spacings and Stephens (1978)' modified Shapiro and Wilk (1972) test for exponentiality. The modification is for the case where the origin is known. We applied the same modification to Kim (2001a)'s statistic, which is based on the ratio of two asymptotically efficient estimates of scale. The simulation results show that Kim (2001a)'s statistic has higher power than Stephens' modified Shapiro and Wilk statistic for almost all cases.

• Journal of the Korean Institute of Intelligent Systems
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• v.22 no.4
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• pp.487-493
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• 2012

SLAM(Simultaneous Localization And Mapping) is a technique used by robots and autonomous vehicles to build up a map within an unknown environment and estimate a place of robot. FastSLAM(A Factored Solution to the SLAM) is one of representative method of SLAM, which is based on particle filter and extended Kalman filter. However it is suffered from loss of particle diversity. In this paper, new approach using fitness sharing is proposed to supplement loss of particle diversity, compared and analyzed with existing methods.

• BMB Reports
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• v.48 no.9
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• pp.487-488
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• 2015

The ubiquitin-proteasome system and the autophagy lysosome system are the two major protein degradation machineries in eukaryotic cells. These two systems coordinate the removal of unwanted intracellular materials, but the mechanism by which they achieve this synchronization is largely unknown. The ubiquitination of substrates serves as a universal degradation signal for both systems. Our study revealed that the amino-terminal Arg, a canonical N-degron in the ubiquitin-proteasome system, also acts as a degradation signal in autophagy. We showed that many ER residents, such as BiP, contain evolutionally conserved arginylation permissive pro-N-degrons, and that certain inducers like dsDNA or proteasome inhibitors cause their translocation into the cytoplasm where they bind misfolded proteins and undergo amino-terminal arginylation by arginyl transferase 1 (ATE1). The amino-terminal Arg of BiP binds p62, which triggers p62 oligomerization and enhances p62-LC3 interaction, thereby stimulating autophagic delivery and degradation of misfolded proteins, promoting cell survival. This study reveals a novel ubiquitin-independent mechanism for the selective autophagy pathway, and provides an insight into how these two major protein degradation pathways communicate in cells to dispose the unwanted proteins. [BMB Reports 2015; 48(9): 487-488]

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.3
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• pp.487-492
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• 2016

In this paper, a device for analyzing the pressure distribution during walking was produced by using the pressure sensor on the heel. This device was limited to a frequency band by using the 1st low-pass filter. And an algorithm to analyze the value of the quantity to pressure using a analog to digital converter. It is used by using the threshold voltage of pressure sensor, it is suggested the algorithm. The algorithm is detected the peak which is exceeded the threshold voltage. and thus in accordance, it is detected the number of steps. And the calorie consumption were detected by using it. Also it used an MCU and Bluetooth. And by confirming the data at the LCD of the other MCU, it was to reduce the size of the device. According to this algorithm, it has the advantage that there is no restriction on the activity than when using an imaging device and it is inexpensive than other sensors such as an acceleration sensor or a gyro and it is easy to handle.