• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.487-488
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• 2005

• Journal of Korean Neurosurgical Society
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• 제58권5호
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• pp.487-490
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• 2015

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a relapsing-remitting disorder for which steroid administration is a key to control the progression. CLIPPERS can exhibit radiological features similar to malignant lymphoma, whose diagnosis is confounded by prior steroid administration. We report a case of CLIPPERS accompanied by abnormal elevation of ${\beta}-2$ microglobulin in the cerebrospinal fluid (CSF). A 62-year-old man started to experience numbness in all fingers of his left hand one year ago, which gradually extended to his body trunk and legs on both sides. Magnetic resonance imaging demonstrated numerous small enhancing spots scattered in his brain and spinal cord. CSF levels of ${\beta}-2$ microglobulin were elevated; although this often indicates central nervous system involvement in leukemia and lymphoma, the lesions were diagnosed as CLIPPERS based on the pathological findings from a biopsy specimen. We emphasize the importance of biopsy to differentiate between CLIPPERS and malignant lymphoma because the temporary radiological response to steroid might be the same in both diseases but the treatment strategies regarding the use of steroid are quite different.

• 한국축산식품학회지
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• 제36권4호
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• pp.487-493
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• 2016

The antimicrobial activity of bovine lactoferrin hydrolysates (bLFH) was measured against Pseudomonas strains (P. syringae and P. fluorescens) in vitro. To compare susceptibility to bLFH, minimal inhibitory concentration (MIC) values were determined using chemiluminescence assays and paper disc plate assays. Antimicrobial effect against P. fluorescens was not observed by either assay, suggesting that bLFH did not exhibit antimicrobial activity against P. fluorescens. However, a significant inhibition of P. syringae growth was observed in the presence of bLFH. The addition of bLFH in liquid or solid medium inhibited growth of P. syringae in a dose-dependent manner. Furthermore, a bLFH peptide with antimicrobial activity toward P. syringae was isolated and identified. The N-terminal amino acid sequences of thus obtained antimicrobial bLFH peptides were analyzed by a protein sequencer and were found to be Leu-Arg-Ile-Pro-Ser-Lys-Val-Asp-Ser-Ala and Phe-Lys-Cys-Arg-Arg-Trp-Gln-Trp-Arg-Met. The latter peptide sequence is known to be characteristic of lactoferricin. Therefore, in the present study, we identified a new antimicrobial peptide against P. syringae, present within the N-terminus and possessing the amino acid sequence of Leu-Arg-Ile-Pro-Ser-Lys-Val-Asp-Ser-Ala.

• Journal of Magnetics
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• 제18권4호
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• pp.487-493
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• 2013

The automotive industry is showing widespread interest in belt-driven electric motor-assisted (e-Assist) systems. A belt-driven assist system (BAS) starts and assists the combustion engine in place of the conventional generator. In this study, a water-cooled wound rotor synchronous motor (WRSM) for the e-Assist system was designed and analyzed. The performance of the WRSM was compared with that of an interior permanent magnet synchronous motor (IPMSM). The WRSM efficiency can be improved for the BAS by adjusting the field flux at high speeds. The field current map to obtain the maximum efficiency based on the speed and torque was developed. To control the field flux via field current control in the WRSM, a general H-bridge circuit was added to the WRSM inverter to get the rapid current response in the high-speed region; the characteristics were compared with the chopper circuit. A WRSM developed for the belt-driven e-Assist system and a prototype 115 V power electronic converter to drive the WRSM were tested with a 900 cc combustion engine. The test results showed that the WRSM-type e-Assist system had good characteristics and could successfully start and assist the 900 cc combustion engine.

• Journal of Power Electronics
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• 제13권3호
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• pp.487-496
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• 2013

The three-phase synchronous reference frame phase-locked loop (SRF-PLL) is widely used for synchronization applications in power systems. In this paper, a new control strategy for three-phase grid-connected LCL inverters without a PLL is presented. According to the new strategy, a current reference can be generated by using the instantaneous power control scheme and the proposed positive-sequence voltage detector. Through theoretical analysis, it is indicated that a high-quality grid current can be produced by introducing the new control strategy. In addition, a kind of independent control for reactive power can be achieved under unbalanced and distorted grid conditions. Finally, the excellent performance of the proposed control strategy is validated by means of simulation and experimental results.

• 대한조선학회논문집
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• 제42권5호
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• pp.487-492
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• 2005

The structural intensity analysis, which calculates vibration energy flow from vibratory velocity and internal force of a structure, can give information on sources' power, dominant transmission path and sink of vibration energy. In this study, we present a system for structural intensity analysis and visualization to apply for anti-vibration design of ship structures. The system calculates structural intensity from the results of forced vibration analysis and visualize the intensity using a general purpose finite element analysis program MSC/Nastran and its pre- and post-processor program. To demonstrate the analysis and visualization capability of the presented system, we show and discuss the results of structural intensity analysis for a cross-stiffened plate and a 70,500 OW crude oil tanker

• 응용통계연구
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• 제18권2호
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• pp.487-497
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• 2005

강의평가는 질 높은 수업을 실현하고 개선${\cdot}$발전시키기 위해서 일련의 수업체계 및 과정을 평가하고, 분석한 결과를 이용하여 강의 내용을 재조직하거나 강의방법을 개선하여 대학교육의 질적 수준을 높이며, 더 나아가 양질의 교육을 제공함으로써 교육 소비자인 학생들의 만족도를 제고시키는데 그 목적이 있다. 즉 강의평가는 교육현장에서 수행되는 강의에 대한 평가를 통하여 교육 소비자인 학생들의 만족도를 제고시키기 위한 서비스품질 측정 도구라 할 수 있다. 본 논문에서는 강의평가를 통한 교육 서비스품질 향상이 중요한 만큼 강의 서비스품질 측정을 위한 타당한 측정도구를 제안하였다.

• 응용통계연구
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• 제23권3호
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• pp.487-495
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• 2010

본 논문에서는 지수분포의 검정에 자주 쓰이는 Shapiro와 Wilk (1972) 통계량과 이의 단점을 보완한 Kim (2001a)의 통계량을 위치모수가 주어지고 척도모수가 미지인 지수분포에서의 전진 제 2종 중도절단자료에 적용하였다. 이를 위하여 각각의 통계량을 Stephens (1978)을 이용하여 위치모수가 주어진 경우의 검정통계량으로 수정하고, 자료를 정규화 간격(normalized spacings)을 이용하여 변환하는 방법을 사용하였다. 모의실험을 통하여 검정력을 비교한 결과 Shapiro-Wilk 통계량보다 Kim (2001a)의 통계량을 이용할 때 고려한 거의 모든 경우 더 우수한 검정력을 나타내었다.

• 한국지능시스템학회논문지
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• 제22권4호
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• pp.487-493
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• 2012

SLAM(Simultaneous Localization And Mapping)은 주변 환경에 대한 지도 작성과 자신의 위치를 인식하는 기법으로 주행 로봇 분야에서 널리 사용되고 있다. FastSLAM(A Factored Solution to the SLAM)은 파티클 필터와 확장형 칼만 필터를 기반으로 한 대표적인 SLAM 기법중의 하나이나, 재추출 단계에서 입자들의 다양성이 상실되는 문제가 제기되고 있다. 본 논문에서는 적합도 공유기법을 사용하여 입자들의 다양성 상실에 관한 문제를 보완하는 방법을 제시하고, 기존의 기법들과 성능을 비교 및 분석한다.

• BMB Reports
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• 제48권9호
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• pp.487-488
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• 2015

The ubiquitin-proteasome system and the autophagy lysosome system are the two major protein degradation machineries in eukaryotic cells. These two systems coordinate the removal of unwanted intracellular materials, but the mechanism by which they achieve this synchronization is largely unknown. The ubiquitination of substrates serves as a universal degradation signal for both systems. Our study revealed that the amino-terminal Arg, a canonical N-degron in the ubiquitin-proteasome system, also acts as a degradation signal in autophagy. We showed that many ER residents, such as BiP, contain evolutionally conserved arginylation permissive pro-N-degrons, and that certain inducers like dsDNA or proteasome inhibitors cause their translocation into the cytoplasm where they bind misfolded proteins and undergo amino-terminal arginylation by arginyl transferase 1 (ATE1). The amino-terminal Arg of BiP binds p62, which triggers p62 oligomerization and enhances p62-LC3 interaction, thereby stimulating autophagic delivery and degradation of misfolded proteins, promoting cell survival. This study reveals a novel ubiquitin-independent mechanism for the selective autophagy pathway, and provides an insight into how these two major protein degradation pathways communicate in cells to dispose the unwanted proteins. [BMB Reports 2015; 48(9): 487-488]