• 제목/요약/키워드: A375-S2

검색결과 385건 처리시간 0.024초

Theoretical Design for the Production of Quinoa (Chenopodium quinoa Willd.) in a Closed Plant Factory

  • Bae, Jong Hyang;Austin, Jirapa;Jeon, Yoon-A;Cha, Mi-Kyung;Cho, Young-Yeol
    • 원예과학기술지
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    • 제34권6호
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    • pp.840-844
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    • 2016
  • Quinoa (Chenopodium quinoa Willd.) is a grain crop with high nutritional value. The leaves and sprouts of quinoa can also be consumed either raw or cooked, providing considerably nutritional value as well as high antioxidant and anticancer activities. This study was carried out to obtain basic data to assist in the practical design of a plant factory with artificial lighting for the cultivation of quinoa as a leafy vegetable. We estimated the energy content of the quinoa and the electrical energy required to produce this crop. The yield was 1,000 plants per day, with a planting density and light intensity of $0.015m^2$ ($15{\times}10cm$) and $200{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$, respectively. The total number of plants, cultivation area, and electricity consumption were estimated to be 25,000, $375m^2$, and $93,750{\mu}mol{\cdot}s^{-1}$, respectively. White fluorescent lamps were used at a power of 20.4 kW from 1,857 fluorescent lamps (FL, 55 W), and the cost for electricity was approximately 1,820 dollars (exchange rate of $1 = 1,200 won) per month. For a daily harvest of 1,000 plants per day in a closed plant factory, the estimated light installation cost, total installation cost, and total production cost would be 15,473, 46,421, and 55,704 dollars, respectively. The calculated production cost per plant, including labor costs, would be 27 cents for the 25-day cultivation period, with a marketable ratio of 80%. Considering the annual total expenses, income, and depreciation costs, the selling price per plant was estimated to be approximately 56 cents.

A Numerical Design and Feasibility Study of Self-Wastage Experiment Using Simulant Material in a Sodium Fast Reactor

  • Jang, Sunghyon;Takata, Takashi;Yamaguchi, Akira
    • Nuclear Engineering and Technology
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    • 제48권2호
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    • pp.368-375
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    • 2016
  • A sodiume-water reaction takes place when high-pressured water vapor leaks into sodium through a tiny defect on the surface of the heat transfer tube in a steam generator of the sodium-cooled fast reactor. The sodiume-water reaction brings deterioration of the mechanical strength of the heat transfer tube at the initial leakage site. As a result, it damages the crack itself, which may eventually enlarge into a larger opening. This self-enlargement is called "self-wastage phenomenon." In this study, a simulant experiment was proposed to reproduce the self-enlargement of a crack and to evaluate the mechanism of the self-wastage. The damage on the surface of the crack was simulated by making the neutralization reaction with hydrochloric acid solution and sodium hydroxide solution. A numerical investigation was carried out to validate the feasibility of the approach and to determine experimental conditions. From the computation results, it is observed that when 5M HCl is injected into 5M of NaOH with 0.05 m/s inlet velocity, the temperature at the surface near the crack increased over 319.26 K. The computational results show that the self-wastage phenomenon is capable of being reproduced by the simulant experiment.

Proteomic Analysis of Protein Expression in Streptococcus pneumoniae in Response to Temperature Shift

  • Lee Myoung-Ro;Bae Song-Mee;Kim Tong-Soo;Lee Kwang-Jun
    • Journal of Microbiology
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    • 제44권4호
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    • pp.375-382
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    • 2006
  • From its initial colonization to causation of disease, Streptococcus pneumoniae has evolved strategies to cope with a number of stressful in vivo environmental conditions. In order to analyze a global view of this organism's response to heat shock, we established a 2-D electrophoresis proteome map of the S. pneumoniae D39 soluble proteins under in vitro culture conditions and performed the comparative proteome analysis to a 37 to $42^{\circ}C$ temperature up-shift in S. pneumoniae. When the temperature of an exponentially growing S. pneumoniae D39 culture was raised to $42^{\circ}C$, the expression level of 25 proteins showed changes when compared to the control. Among these 25 proteins, 12 were identified by MALDI-TOF and LC-coupled ESI MS/MS. The identified proteins were shown to be involved in the general stress response, energy metabolism, nucleotide biosynthesis pathways, and purine metabolism. These results provide clues for understanding the mechanism of adaptation to heat shock by S. pneumoniae and may facilitate the assessment of a possible role for these proteins in the physiology and pathogenesis of this pathogen.

청소년기의 열량영양소 섭취양상과 혈압 (Macronutrient Intake and Blood Pressure of Adolescents in Rural Korea)

  • 김영옥;서일;남정모;김석일;박임수;안홍석
    • 대한지역사회영양학회지
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    • 제1권3호
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    • pp.366-375
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    • 1996
  • The effect of carbohydrates, fat and protein consumption on the blood pressure of adolescents was investigated from the cross sectional data. The two major areas of inquiry were : 1)measuring the variation of blood pressure at various levels of macronutient intake. 2)measuring the relative importance between the factor of nutrient intake and physical growth. A total of 726 students(341 boys and 385 girls) in the first grade of middle school in Kangwha country were studied for their dietary consumption and physical growth as well as blood pressure. Multiple regression analysis was used as the analytical method to identify the relative importance between the factors. Besides the macronutrient consumption, other nutrients such as vitamin and mineral intakes were included in the regression model. The results showed a variation of blood pressure by macronutrient intake level was in consistant both in blood pressure and by gender. Systolic and diastolic blood pressure decreased with increasing protein intake for girls(p<0.05). However, it was not observed in the case of boys. The systolic blood pressure of boys showed a tendency to decrease with fat intake increase, while their diastolic blood pressure showed the opposite trend. Results of the regression analysis showed that physical growth was a more influential factor than nutrition on blood pressure for both sexes. This could imply that the dietary hypertension factors observed in adults may not be operative generally in a population with normotensive blood pressure during growth.

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인간 대장암 세포 HT-29에서 Aloin에 의한 Apoptosis 유도 (Induction of Apoptosis in HT-29 Human Colorectal Cancer by Aloin)

  • 유은선;우중석;김성현;이재한;한소희;정수현;박영석;김병수;김상기;박병권;정지윤
    • 한국식품위생안전성학회지
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    • 제34권5호
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    • pp.495-501
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    • 2019
  • Aloin [1,8-Dihydroxy-10-(${\beta}$-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone]은 알로에에서 추출한 천연 안트라퀴논이다. 다양한 유형의 인간 암세포에서 항산화, 항암 효과가 있는 것으로 밝혀졌지만 인간 대장암 세포 HT-29에서 aloin의 항암 효과는 밝혀지지 않았다. 본 연구에서는 aloin이 인간 대장암 HT-29 세포에서 세포 사멸 작용을 발휘할 수 있는 메커니즘을 조사하였다. Aloin이 세포 생존율에 영향을 미치는지 알아보기 위해 대장암 세포 HT-29, 흑색종 세포 A375SM, 위암 세포 AGS를 aloin(0, 100, 200, 300 및 $400{\mu}M$)으로 처리하였을 때, HT29에서는 농도 의존적으로 세포 생존율을 감소시켰고, A375SM과 AGS 세포에서는 암세포 생존율의 감소가 보이지 않았다. 이러한 HT-29에서의 세포 생존율 감소가 세포자멸사로 인한 감소인지 확인하기 위해 DAPI stain과 flow cytometry를 실시한 결과 apoptotic body가 유의적으로 증가하고 세포 자멸사가 증가한 것을 확인할 수 있었다. 이와 같은 결과를 바탕으로 aloin이 대장암 세포 HT-29에서 세포 사멸 관련 단백질 발현 양상에 미치는 영향을 확인하기 위해 western blotting을 실시하였다. Aloin은 Bax, PARP의 분절을 농도 의존적으로 증가시켰고, caspase3, -8을 활성화시켰지만, Bcl-2는 대조군에 비해 변화가 없었다. Aloin에 의해 유도된 세포자멸사 기전을 확인하기 위해 MAPK pathway 중 p-p38과 p-ERK의 발현을 확인한 결과, p-p38을 up-regulation시키고 p-ERK의 down-regulation을 유도했다. 따라서, aloin은 인간 대장암에서 암세포 성장 억제 효과 및 암세포 사멸 유도로 암예방 약제로서의 개발 가능성이 있다고 사료된다.

수직형 폴리머 마이크로링 공진기 기반의 글루코스 바이오 센서 (Refractometric Glucose Biosensor Incorporating a Vertically Coupled Microring Resonator in Polymeric Waveguides)

  • 김건덕;손근식;이학순;김기도;이상신
    • 한국광학회지
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    • 제19권2호
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    • pp.127-131
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    • 2008
  • 본 논문에서는 굴절률 감지 방식의 수직 결합형 폴리머 마이크로링 공진기 기반 글루코스 바이오 센서를 제안하고 구현하였다. 이 센서에서 상부 클래딩 역할을 하는 글루코스 분석 대상물의 농도 변화는 링 공진기의 공진파장 이동을 측정함으로써 얻어진다. 특히, 센서의 감도를 향상시키기 위해 다음과 같은 방법을 사용하였다. 첫째로, 분석 대상물에 근접한 유효굴절률을 갖는 폴리머 도파로 구조를 공진기 센서에 도입하였다. 둘째로, 분석 물질의 접촉면적을 확대하기 위해 측면 클래딩층이 충분히 식각된 pedestal 링 도파로 구조를 사용하였다. 제안된 공진기 센서는 빔전파 방법을 사용하여 설계하고 분석하였다. 사용된 코어 및 클래딩용 폴리머의 굴절률은 각각 1.430과 1.375였으며, 링 반경은 $400\;{\mu}m$였다. 이 때 얻어진 도파로의 유효굴절률은 ${\sim}1.390$였으며 글루코스 수용액의 굴절률 1.333와 매우 근접하였다. 제작된 소자의 기본적인 전달특성은 FSR(free spectral range) 0.66 nm, 대역폭 ${\sim}0.15\;nm$, Q 값 10,000 이었다. 1550 nm 광파장 대역에서 얻어진 측정 결과를 살펴보면, 센서 감도는 ${\sim}0.28\;pm$/(mg/dL)였으며, 이에 따른 굴절률 변화 감도는 ${\sim}200\;nm/RIU$였다.

Breast Density and Risk of Breast Cancer in Asian Women: A Meta-analysis of Observational Studies

  • Bae, Jong-Myon;Kim, Eun Hee
    • Journal of Preventive Medicine and Public Health
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    • 제49권6호
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    • pp.367-375
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    • 2016
  • Objectives: The established theory that breast density is an independent predictor of breast cancer risk is based on studies targeting white women in the West. More Asian women than Western women have dense breasts, but the incidence of breast cancer is lower among Asian women. This meta-analysis investigated the association between breast density in mammography and breast cancer risk in Asian women. Methods: PubMed and Scopus were searched, and the final date of publication was set as December 31, 2015. The effect size in each article was calculated using the interval-collapse method. Summary effect sizes (sESs) and 95% confidence intervals (CIs) were calculated by conducting a meta-analysis applying a random effect model. To investigate the dose-response relationship, random effect dose-response meta-regression (RE-DRMR) was conducted. Results: Six analytical epidemiology studies in total were selected, including one cohort study and five case-control studies. A total of 17 datasets were constructed by type of breast density index and menopausal status. In analyzing the subgroups of premenopausal vs. postmenopausal women, the percent density (PD) index was confirmed to be associated with a significantly elevated risk for breast cancer (sES, 2.21; 95% CI, 1.52 to 3.21; $I^2=50.0%$). The RE-DRMR results showed that the risk of breast cancer increased 1.73 times for each 25% increase in PD in postmenopausal women (95% CI, 1.20 to 2.47). Conclusions: In Asian women, breast cancer risk increased with breast density measured using the PD index, regardless of menopausal status. We propose the further development of a breast cancer risk prediction model based on the application of PD in Asian women.

Evacuation Safety Evaluation of Tourist Hotels with the Fire Alarm Method

  • Moon, Sung-Chun;Kong, Ha-Sung
    • International Journal of Advanced Culture Technology
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    • 제9권4호
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    • pp.363-375
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    • 2021
  • The purpose of this study is to analyze the safety of evacuation using the Pathfinder program for the alert at once, the priority alarm method, the priority alarm method for the four floors above, and the sequential priority alarm method, which is a modification of the priority alarm method specified in the tourist hotel building. Currently, in Korea's National Fire Safety Codes (NFSC), fire alarm methods are compulsorily applied differently depending on the number of floors and total floor area of a building. Although the growth rate is getting faster due to the diversification of building structures, it is still an obstacle to improving evacuation safety to comply with the standardized fire alarm method in NFSC. As a result of the experiment, the evacuation time was found to be faster with the priority alarm method for the four floors above than the priority alarm method applied to the specific firefighting object. Compared to the priority alarm method applied to the tourist hotel, which is a specific firefighting target with 5 or more floors and a total floor area of more than 3,000m2, the time was shortened by 3.7 seconds when measured by applying the priority alarm method for the four floors directly above. This indicates that it is necessary to take measures to select a fire alarm method suitable for the structure and environmental conditions of the building rather than applying the uniform NFSC regulations.

이중 변환 UPS의 병렬 운전 시 외란 저감 성능 향상을 위한 정지 좌표계 상의 전향 보상 기법 (Feed-Forward Compensation Technique in Stationary Reference Frame for the Enhanced Disturbance Rejection Performance in Parallel Operation of Double-Conversion UPSs)

  • 류효준;윤영두;모재성;최승철;우태겸
    • 전력전자학회논문지
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    • 제27권5호
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    • pp.367-375
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    • 2022
  • Generally, a proportional-resonant controller is used to eliminate steady-state errors during the voltage-current control of a double-conversion uninterruptible power supply (UPS) in a stationary reference frame. Additionally, the feed-forward control compensating for the load current, which can be considered a disturbance of the voltage controller, can be used to improve the disturbance rejection performance. However, during the parallel operation of UPSs, circulating current can occur between UPS modules when performing both feed-forward control and droop control because feed-forward control reduces the circulating current impedance. This study proposes a feed-forward compensation technique that considers the impedance of circulating current. An additional feed-forward compensation technique is developed to enhance the disturbance rejection performance. The validity of the proposed feed-forward compensation technique is verified by the experiment results of the parallel operation of a 500 W double-conversion UPS module.

Xenopus laevis 초기 배의 동물극 분리배양에서 bFGF와 HGF 혼합처리에 의한 기관유도 (Organ Induction by Combined Dose of bFGF and HGF in Animal Cap Assay of Early Xenopus laevis Embryos.)

  • 진정효;윤춘식;이호선;박용욱;정선우
    • 생명과학회지
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    • 제14권3호
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    • pp.375-384
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    • 2004
  • FGFs는 Xenopus의 초기 배발생에서 중배엽 형성, 전후축패턴형성, scatter factor로서 낭배기의 기관형성에 관여하는 등 다양한 기능을 가지고 있는 것으로 알려져 있다 그 중 bFGF는 배양 분리편으로부터 다양한 기관을 유도해낼 수 있으며 그 효과는 처리시간 및 농도 의존적이라고 알려져 왔다. 본 연구는 Xenopus의 예정표피역을 분리하여 bFGF와 HGF을 단독 및 복합처리 하였을 때 기관분화 및 유도효과를 검토하기 위하여 실시하였다. 단독처리 및 복합 처리된 배양액에 동물극 분리편을 정상배가 st. 43에 이를 때까지 2$0^{\circ}C$에서 3일간 배양하여 조직학적 및 면역조직화학적 방법으로 조직의 분화양상을 확인하였다. 성장인자는 bFGF를 0, 0.5, 1. 10. 50 ng/ml의 농도와 HGF를 0, 1, 10, 50, 100ng/ml의 농도로 조합하여 처리한 결과 bFGF 단독처리 때보다 HGF와의 혼합처리에서 기관분화율의 상승효과가 관찰되었다. 분화된 기관은 1 ng/ml의 bFGF 와 10ng/ml의 HGF, 10ng/ml의 bFGF와 1ng/ml의 HGF의 농도에서 매우 다양한 것으로 나타났다. 눈은 1과 10ng/ml의 bFGF ,그리고 1과 10 ng/ml의 HGF 농도조합에서 높은 비율로 분화하였다. 또한 분리편 배양에 의해 유도된 눈과 정상 배의 눈에서 RPE65를 인식하는 단일클론 항체 40All, 25F5를 사용하여 AP 반응이 강하게 나타나 눈의 유도를 확인할 수 있었다.