• Title/Summary/Keyword: A.I 4D cycle

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Study on Sensory Papillae of Metagonimus yokogawai Cercaria (Metagonimus yokogawai 세르카리아의 감각유두에 관한 연구)

  • 김재진;민득영소진탁
    • Parasites, Hosts and Diseases
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    • v.22 no.1
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    • pp.11-20
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    • 1984
  • A number of studies on the papillae of cercariae of trematodes reported that the papillar patterns (or chaetotaxy) of cercariae might be an excellent method to attain better understanding of the digenetic trematodes (Richard, 1971 ; Short and Cartrett, 1973; Bayssade-Dufour, 1979) . The present study was aimed to determine the number, distribution pattern and structure of the sensory papillae of Metagonimus yokogawai cercariae, and to elucidate the chaetotaxy of this digenetic trematode. M. yokogawai cercariae were pipetted from a vial in which infected snails (Semisulcospira libertina) had been kept for 3 hours. The snails were collected from an endemic area of M. yokogawai, Boseong river in west-southern part of Korea. Observations of papillae were based on light microscopy of those stained with silver nitrate, and on scanning electron microscopy The results are summarized as follows: 1, All papillae observed were uniciliated. 2. Cilia in anterior tip were shorter than the others in other portions. 3. The body papillae were arranged in essentially symmetrical patterns, Total number of the papillae was 126(63 pairs) in average; anterior tip 40(20 pairs), ventral 20(10 pairs), lateral 42(21 pairs), and caudal 8(4 pairs). 4. The chaetotany of M. yokogawai cercaria was: Ci cycle ($3+3C_{I}V,{\;}2+2C_{I}L,{\;}2+3C_{I}D),{\;}C_{II}{\;}cycle(2C_{II}V,{\;}1C_{II}L,{\;}2C_{II}D),{\;}C_{lll}{\;}cycle{\;}(1+lC_{III}V,{\;}1C_{IlI}L),{\;}C_{IV}{\;}cycle{\;}(1C_{IV}V,{\;}IC_{lV}L){\;}in{\;}cephalic{\;}region:{\;}A_I(1A_{IV}V,{\;}1+2A_{I}L,{\;}1A_{I}D),{\;}A_{II}(1A_{II}V,{\;}1+3A_{II}L,{\;}1A_{II}D),{\;}A_{III}(1A_{III}V,{\;}1+1A_{III}L,{\;}1A_{III}D){\;}and{\;}A_{IV}(1A_{IV}V,{\;}2A_{IV}L)$ in antacetabular region: $1M_{I}V{\;}and{\;}2M_{I}L$ in median: $1+1P_{I}L,{\;}1P_{II}L,{\;}1P_{II}D,{\;}1P_{III}L,{\;}1P_{IV}L{\;}and{\;}1P_{IV}D$ in postacetabular region: 2-2-2-2 in caudal region.

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Faith Community Education for Shalom in Conflict Society : Focusing on ABCD, A.I 4D, and Dialogue (갈등사회의 샬롬을 위한 신앙공동체 교육 : ABCD, A.I 4D, 대화를 중심으로)

  • Ha Eun Chung
    • Journal of Christian Education in Korea
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    • v.75
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    • pp.153-170
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    • 2023
  • Purpose of study: This study seeks practical ways to resolve conflicts between church and religious community members in modern society living in an age of division and conflict. Research content and method: First, the phenomenon and causes of a society of division and conflict were examined. Second shalom was studied to restore division and conflict. Third values were discovered along with the ABCD theory for the development of an asset-based community in order to solve a society of conflict with shalom. 4D cycle strategy of A.I. Fourth in order to restore the conflicts of the faith community to shalom, the ABCD theory and the 4D of A.I. were presented with ways to manage conflicts, minimize division, and restore shalom through dialogue and storytelling tools. Conclusions and Suggestions: The various conflicts in our society can be restored when all Christians discover their vocation and talent through the method of dialogue for shalom, solidarity as a community of faith, and achieve shalom. Therefore it is necessary to educate the Shalom faith community through dialogue for Shalom.

LMI-Based Robust Controllers for DC-DC Cascade Boost Converters

  • Torres-Pinzon, Carlos Andres;Giral, Roberto;Leyva, Ramon
    • Journal of Power Electronics
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    • v.12 no.4
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    • pp.538-547
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    • 2012
  • This paper presents two different robust controllers for boost converters with two stages in a cascade. The first robust controller is monovariable; that is, the duty-cycle is the same for the two switches. The monovariable controller ensures that some prescribed constraints on pole placement and control effort are met, and optimizes the load disturbance rejection, while takes into account the uncertainty in certain parameters. The first controller is then compared with a multivariable robust controller; that is, with independent duty cycles in each switch. The multivariable controller takes into account the same uncertainty, constraints and optimization function. The comparison shows that the multivariable controller performs better at the expense of a slightly more complex implementation; that is, the multivariable controller provides a better rejection of the load disturbance. The paper also describes simulations and experimental results that are in perfect agreement with theoretical derivations.

Nitrification/Denitrification Rate and Classification of Output Nitrogen according to COD Loads in SBR (연속회분식 공정에서 COD부하에 따른 질산화/탈질율 및 유출질소 분휴)

  • Lee, Jaekune;Yim, Soobin
    • Journal of Korean Society on Water Environment
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    • v.24 no.1
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    • pp.30-35
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    • 2008
  • In this study, we investigated the nitrification/denitrification rate and classification of output nitrogen of a sequencing batch reactor (SBR) system with the variation of COD loads ; COD loads of 0.3, 0.4, 0.6, 0.7, 0.8, 1.0 and $1.2kgCOD/m^3{\cdot}d$ were tested to determine the optimum conditions for the operation of the SBR and increase its nitrogen removal efficiency. As the COD loads increased, the nitrification rate at aerobic(I) period and the denitrification rate at anoxic(I) period were decreased. With the variation of COD loads, the amounts of nitrogen removed in the clarified water effluent were 63.9, 54.2, 34.7, 22.5, 13.7, 12.5 and 26.5 mg/cycle, respectively. The amounts of nitrogen removed during the sludge waste process were 19.5, 26.6, 41.0, 47.3, 58.1, 72.4 and 88.1 mg/cycle, respectively. The amounts of nitrogen removed by denitrification were 66.8, 69.3, 68.9, 56.5, 39.5, 7.3 and 0.0 mg/cycle, respectively, indicating that COD load more than $0.7kgCOD/m^3{\cdot}d$ decreases the amounts of denitrified nitrogen. The nitrogen mass balances were calculated as the percentages of nitrogen removed in the clarified water effluent or by denitrification and sludge waste processing in each cycle of SBR operation and were 99.0, 98.5, 95.4, 82.1, 73.0, 60.5 and 74.8% for COD loads of 0.3, 0.4, 0.6, 0.7, 0.8, 1.0 and $1.2kgCOD/m^3{\cdot}d$, respectively.

Remineralization effect according to application cycle of fluoride varnish: QLF-D analysis (불소바니쉬 도포주기에 따른 재광화 평가: QLF-D의 활용)

  • Jeon, Eun-Young;Lee, Su-Young
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.4
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    • pp.525-530
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    • 2016
  • Objectives: The purpose of the study is to investigate remineralization effect according to application cycle of fluoride varnish in preschool children. Methods: The study subjects were fifty six children (92 teeth) having one or more early dental caries lesion. Fluoride varnish was applied to the primary area of maxillary and anterior mandibular teeth with the interval of one month, three months, and six months. Results: Dft index was 3.54 in male and 3.44 in female. The fluorescence loss(${\Delta}F$) value due to early caries lesions showed a significant difference in experiment groups I and II after the application of fluoride varnish, but there was no significant difference in experiment group III. After fluoride varnish application, there was a significant change in experimental group I and III. The maximum fluorescence loss(${\Delta}Fmax$) from early caries lesions showed a significant difference after application of the fluoride varnish in all three experiment groups of I, II, and III(p<0.001). Conclusions: Fluoride varnish should be recommended and applied to the children of high risk caries group in every three months.

Ethanol extract of Innotus obliquus (Chaga mushroom) induces $G_1$ cell cycle arrest in HT-29 human colon cancer cells

  • Lee, Hyun Sook;Kim, Eun Ji;Kim, Sun Hyo
    • Nutrition Research and Practice
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    • v.9 no.2
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    • pp.111-116
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    • 2015
  • BACKGROUND/OBJECTIVES: Inonotus obliquus (I. obliquus, Chaga mushroom) has long been used as a folk medicine to treat cancer. In the present study, we examined whether or not ethanol extract of I. obliquus (EEIO) inhibits cell cycle progression in HT-29 human colon cancer cells, in addition to its mechanism of action. MATERIALS/METHODS: To examine the effects of Inonotus obliquus on the cell cycle progression and the molecular mechanism in colon cancer cells, HT-29 human colon cancer cells were cultured in the presence of $2.5-10{\mu}g/mL$ of EEIO, and analyzed the cell cycle arrest by flow cytometry and the cell cycle controlling protein expression by Western blotting. RESULTS: Treatment cells with $2.5-10{\mu}g/mL$ of EEIO reduced viable HT-29 cell numbers and DNA synthesis, increased the percentage of cells in $G_1$ phase, decreased protein expression of CDK2, CDK4, and cyclin D1, increased expression of p21, p27, and p53, and inhibited phosphorylation of Rb and E2F1 expression. Among I. obliquus fractions, fraction 2 (fractionated by dichloromethane from EEIO) showed the same effect as EEIO treatment on cell proliferation and cell cycle-related protein levels. CONCLUSIONS: These results demonstrate that fraction 2 is the major fraction that induces $G_1$ arrest and inhibits cell proliferation, suggesting I. obliquus could be used as a natural anti-cancer ingredient in the food and/or pharmaceutical industry.

Inhibitory Mechanisms of Cell Cycle Regulation Induced by Indole-3-carbinol in Hepatocellular Carci-noma HepG2 Cells. (간암 세포주에서의 Indole-3-Carbinol에 의해 유도되는 세포주기 억제 기전)

  • 김동우;이광수;김민경;조율희;이철훈
    • Microbiology and Biotechnology Letters
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    • v.29 no.3
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    • pp.181-185
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    • 2001
  • The naturally occurring chemical indole-3-carbinol (13C), found in vegetables of the Brassica genus, is a promising anticancer agent that was shown previ- ously to induce a Gl cell cycle arrest of human breast cancer cell lines, independent of estrogen receptor signaling. The anticancer activity of 13C and the possible mechanisms of its action were explored in a human hepatocellular carcinoma cell line, HepG2. Treatment of HepG2 cells with 13C suppressed the growth of the cells. The growth sup- pression caused by 13C ($IC_{50}$/: 444$\mu$M) was found to be partially due to its ability to stop the cell cycle in HepG2 cells. Western blot analysis for the Gl phase artiest demonstrated that the expression-levels of cyclin-dependent kinase (Cdk4, Cdk6) and cyclic D were reduced strongly after treatment of Hep72 cells with 13C (4007M) for 24- 72 hrs. Furthermore, I3C selectively abolished the expression of Cdk6 in a dose- and time-dependent manner, and accordingly, inhibited the phosphorylation of retinoblastoma. Interestingly, after the HepG2 cells reached their max- imal growth arrest, the level of the p21, a well-known Cdk inhibitor, increased significantly. Therefore, it could be considered that the Gl arrest of HepG2 cells treated with 13C was due to the indirect inhibition of Cdk4/6 activities by p21 Western blot analysis for G2/M phase arrest of demonstrated the levels of Cdc2 and cyclin Bl werer reduced dramatically after the treatment of HepG2 cells with 13C ($40\mu$M) for 24-72 hrs. flow cytometry of propidium iodide-stained HepG2 cells revealed that 13C induces a Gl (53%,72hr incubation) and G2 (25%,24hr incubation) cell cycle arrest. Thus, our observations have uncovered a previously undefined antiproliferative pathway for r3C that implicates Cdk4/6 and Cdc2 as a target for cell cycle control in human HepG2 cells. However, the 13C-medi- ated cell cycle arrest and repression of Cdk4/6 production did not affect the apoptotic induction of HepG2 cell.

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A Study on Typical Rates of Water-use for Primary School, Middle School and High School Facilities (초.중.고등학교 시설의 급수 사용량에 대한 연구)

  • Kim, Kyu-Saeng
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.20 no.12
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    • pp.802-807
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    • 2008
  • A Study on Typical Rates of Water-use for School Facilities has been carried out in this work. Water supply system is given much weight in school facilities. Therefore, it set up a basis efficiency using of water sources to calculate typical rates of water use. The results are summarized as follows; 1) On the whole, typical rates of water-use was founded out 15 L/stu. d in pirmary school, 10 L/stu. d in middle school and 30 L/stu. d in high school smaller than the existing it. It was rate of water-use change as season and Max. Rates of water-use was July. 2) I deem that school hours are 5 hour's in primary school, 7 hour's in middle school and 8 hour's in high school. It the concept of 1 hour that is lesson time 40 minutes and resting time 10 minutes in primary school, lesson time 45 minutes and resting time 10 minutes in middle school and lesson time 50 minutes and resting time 10 minutes in high school. 3) It is desired that we calculate the volume of pump and water tank throughout this concept and the size of water tank should be 1.5 times with taking peak load into consideration by this study on typical rate of water-use. 4) The amount of using water increases in gradually and I consider the life cycle of facilities is more than 10 years. As a result, I can forecast that the size will be insufficiency but I deem that if we devise a plan about parallel pumping on water tank space, we can cope with it. Also, it is expected that we can cut back the transport energy by controlling pump volume.

Fe3O4 Nanoparticles on MWCNTs Backbone for Lithium Ion Batteries

  • Lee, Kangsoo;Shin, Seo Yoon;Yoon, Young Soo
    • Journal of the Korean Ceramic Society
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    • v.53 no.3
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    • pp.376-380
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    • 2016
  • A composite electrode made of iron oxide nanoparticles/multi-wall carbon nanotube (iNPs/M) delivers high specific capacity and cycle durability. At a rate of $200mAg^{-1}$, the electrode shows a high discharge capacity of ${\sim}664mAhg^{-1}$ after 100 cycles, which is ~ 70% of the theoretical capacity of $Fe_3O_4$. Carbon black, carbon nanotube, and graphene as anode materials have been explored to improve the electrical conductivity and cycle stability in Li ion batteries. Herein, iron oxide nanoparticles on acid treated MWCNTs as a conductive platform are combined to enhance the drawbacks of $Fe_3O_4$ such as low electrical conductivity and volume expansion during the alloying/dealloying process. Enhanced performance was achieved due to a synergistic effect between electrically 3D networks of conductive MWCNTs and the high Li ion storage ability of $Fe_3O_4$ nanoparticles (iNPs).

Influence of Filling Density in the Positive Active-material on the Cycle-life Performance of the Tubular Type Gelled Valve Regulated Lead Acid Batteries (튜브식 겔형 납축전지에 있어서 활물질 밀도에 따른 싸이클 수명 특성)

  • Yoon, Youn-Saup;Kim, Byung-Kwan;Lee, Soo;Kim, Kyu-Tea
    • Applied Chemistry for Engineering
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    • v.10 no.3
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    • pp.415-418
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    • 1999
  • The characteristics of VRLA (valve regulated Iead-acid) battery with the tubular positive plate and gel type electrolyte were examined as a function of active material filling density. The filling density of positive plate was 3.2 g/mL, 3.4 g/mL, and 3.6 g/mL, respectively. These VRLA batteries were cycled with 100% DOD (depth of discharge) at the $C_5/5$ rate, followed by IU-type recharge with $I_{max}=0.2C_{10}/10$ and a final voltage V=2.40 V/cell. The test was performed in a thermostatic room at $25{\pm}1^{\circ}C$. The result indicated that the initial capacity was independent of active material filling density, i.e., the highest initial capacity was 3.4 g/mL of filling density and the lowest was 3.6 g/mL. On aspect of the cycle-life performance of the VRLA battery, the filling density of 3.6 g/mL was similar to that of 3.4 g/mL in the positive plate, and both were higher than that of 3.2 g/mL. Water-loss and degradation of the VRLA battery were decreased according to an increase of the filling density in the positive plate. The optimum filling density of the active material was 3.4~3.6 g/mL.

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